{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T11:08:31Z","timestamp":1790420911029,"version":"4.1.0"},"reference-count":53,"publisher":"American Chemical Society (ACS)","issue":"30","license":[{"start":{"date-parts":[[2026,7,20]],"date-time":"2026-07-20T00:00:00Z","timestamp":1784505600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100005946","name":"Hokkaido University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005946","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000781","name":"European Research Council","doi-asserted-by":"publisher","award":["694228"],"award-info":[{"award-number":["694228"]}],"id":[{"id":"10.13039\/501100000781","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001700","name":"Ministry of Education, Culture, Sports, Science and Technology","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001700","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004189","name":"Max-Planck-Gesellschaft","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004189","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100018992","name":"Fonds der Chemischen Industrie","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100018992","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010661","name":"Horizon 2020 Framework Programme","doi-asserted-by":"publisher","award":["101055472"],"award-info":[{"award-number":["101055472"]}],"id":[{"id":"10.13039\/100010661","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100025019","name":"Support for Pioneering Research Initiated by the Next Generation","doi-asserted-by":"publisher","award":["JPMJSP2119"],"award-info":[{"award-number":["JPMJSP2119"]}],"id":[{"id":"10.13039\/501100025019","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100005156","name":"Alexander von Humboldt-Stiftung","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100005156","id-type":"DOI","asserted-by":"publisher"}]},{"name":"German Research Council (DFG)","award":["EXC2033 390677874RESOLV"],"award-info":[{"award-number":["EXC2033 390677874RESOLV"]}]},{"name":"Research Center for Computational Science, Okazaki, Japan","award":["24-IMS-C114"],"award-info":[{"award-number":["24-IMS-C114"]}]},{"name":"Research Center for Computational Science, Okazaki, Japan","award":["25-IMSC115"],"award-info":[{"award-number":["25-IMSC115"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,8,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Cyclogeranyl motifs are important in natural products and terpene synthesis, yet their asymmetric formation from acyclic dienes remains challenging. Here, we report a general catalytic asymmetric cyclization of geranyl derivatives using confined chiral imidodiphosphorimidate (IDPi) Br\u00f8nsted acids. In combination with fluorinated alcohol additives, the reaction proceeds under mild conditions with high efficiency and excellent regio- and enantioselectivity. The method accommodates diverse substrates, enabling access to fragrance-relevant scaffolds, retinal precursors, complex polycyclic terpenes, and even selective squalene cyclization. Mechanistic studies support a cooperative catalyst\u2013additive hydrogen-bonding network and an asynchronous concerted, enzyme-like transition state within a confined chiral environment. This work provides a general solution for asymmetric geranyl cyclizations and expands the utility of confined Br\u00f8nsted acid catalysis in biomimetic terpene synthesis.<\/jats:p>","DOI":"10.1021\/jacs.6c08353","type":"journal-article","created":{"date-parts":[[2026,7,20]],"date-time":"2026-07-20T18:33:26Z","timestamp":1784572406000},"page":"31649-31655","source":"Crossref","is-referenced-by-count":1,"title":["Catalytic Asymmetric\nCationic Geranyl Cyclizations"],"prefix":"10.1021","volume":"148","author":[{"given":"Na","family":"Luo","sequence":"first","affiliation":[{"name":"Max-Planck-Institut fu\u0308r Kohlenforschung , ,","place":["Mu\u0308lheim an der Ruhr, Germany, 45470"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mathias","family":"Turberg","sequence":"additional","affiliation":[{"name":"Max-Planck-Institut fu\u0308r Kohlenforschung , ,","place":["Mu\u0308lheim an der Ruhr, Germany, 45470"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3226-6201","authenticated-orcid":true,"given":"Nobuya","family":"Tsuji","sequence":"additional","affiliation":[{"name":"Hokkaido University , , ,","place":["Sapporo, Japan, 001-0021"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8171-9399","authenticated-orcid":true,"given":"Markus","family":"Leutzsch","sequence":"additional","affiliation":[{"name":"Max-Planck-Institut fu\u0308r Kohlenforschung , ,","place":["Mu\u0308lheim an der Ruhr, Germany, 45470"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sebastian","family":"Brunen","sequence":"additional","affiliation":[{"name":"Max-Planck-Institut fu\u0308r Kohlenforschung , ,","place":["Mu\u0308lheim an der Ruhr, Germany, 45470"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9804-599X","authenticated-orcid":true,"given":"Benjamin","family":"List","sequence":"additional","affiliation":[{"name":"Max-Planck-Institut fu\u0308r Kohlenforschung , ,","place":["Mu\u0308lheim an der Ruhr, Germany, 45470"]},{"name":"Hokkaido University , , ,","place":["Sapporo, Japan, 001-0021"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2026,7,20]]},"reference":[{"key":"2026080511082313200_cit1","doi-asserted-by":"publisher","first-page":"1226","DOI":"10.1039\/c3np70047j","article-title":"Natural\nSesquiterpenoids","volume":"30","author":"Fraga","year":"2013","journal-title":"Nat. Prod. Rep."},{"key":"2026080511082313200_cit2","doi-asserted-by":"publisher","first-page":"408","DOI":"10.1038\/nchembio.2007.5","article-title":"The Function of Terpene\nNatural Products in the Natural\nWorld","volume":"3","author":"Gershenzon","year":"2007","journal-title":"Nat. Chem. Biol."},{"key":"2026080511082313200_cit3","doi-asserted-by":"publisher","first-page":"5068","DOI":"10.1021\/ja01624a038","article-title":"The Stereochemistry\nof Polyene Cyclization","volume":"77","author":"Stork","year":"1955","journal-title":"J. Am. Chem. Soc."},{"key":"2026080511082313200_cit4","doi-asserted-by":"publisher","first-page":"1890","DOI":"10.1002\/hlca.19550380728","article-title":"Zur Kenntnis der Triterpene.\n190. Mitteilung. Eine Stereochemische Interpretation der Biogenetischen\nIsoprenregel bei den Triterpenen","volume":"38","author":"Eschenmoser","year":"1955","journal-title":"Helv. Chim.\nActa"},{"key":"2026080511082313200_cit5","doi-asserted-by":"publisher","first-page":"3011","DOI":"10.1002\/hlca.200590245","article-title":"Revisited after 50 Years: The \u201cStereochemical\nInterpretation of the Biogenetic Isoprene Rule for the Triterpenes\u201d","volume":"88","author":"Eschenmoser","year":"2005","journal-title":"Helv. Chim. Acta"},{"key":"2026080511082313200_cit6","doi-asserted-by":"publisher","first-page":"4730","DOI":"10.1021\/cr040623l","article-title":"A Case Study in Biomimetic Total Synthesis: Polyolefin\nCarbocyclizations to Terpenes and Steroids","volume":"105","author":"Yoder","year":"2005","journal-title":"Chem. Rev."},{"key":"2026080511082313200_cit7","doi-asserted-by":"publisher","first-page":"1619","DOI":"10.1039\/C9NP00003H","article-title":"En Route to\nTerpene Natural Products Utilizing Supramolecular Cyclase Mimetics","volume":"36","author":"Zhang","year":"2019","journal-title":"Nat. Prod. Rep."},{"key":"2026080511082313200_cit8","doi-asserted-by":"publisher","first-page":"1557","DOI":"10.1039\/C5CS00105F","article-title":"Cascade polycyclizations in natural product synthesis","volume":"45","author":"Ardkhean","year":"2016","journal-title":"Chem. Soc. Rev."},{"key":"2026080511082313200_cit9","doi-asserted-by":"publisher","first-page":"5454","DOI":"10.1039\/C6OB00375C","article-title":"Enantioselective polyene cyclization","volume":"14","author":"Ungarean","year":"2016","journal-title":"Org. Biomol. Chem."},{"key":"2026080511082313200_cit10","doi-asserted-by":"publisher","first-page":"5822","DOI":"10.3390\/molecules25245822","article-title":"Ionone Is\nMore than a Violet\u2019s Fragrance: A Review","volume":"25","author":"Aloum","year":"2020","journal-title":"Molecules"},{"key":"2026080511082313200_cit11","doi-asserted-by":"publisher","first-page":"39011","DOI":"10.1021\/jacs.5c13725","article-title":"Catalytic Enantioselective\nDiels-Alder Reaction of Dienes with Acyclic and \u03b1,\u03b2- and\n\u03b2,\u03b2-Disubstituted Enones","volume":"147","author":"Samsonowicz-Gorski","year":"2025","journal-title":"J. Am.\nChem. Soc."},{"key":"2026080511082313200_cit12","doi-asserted-by":"publisher","first-page":"19643","DOI":"10.1038\/s41598-020-76624-y","article-title":"Construction of an Artificial System\nfor Ambrein Biosynthesis and Investigation of Some Biological Activities\nof Ambrein","volume":"10","author":"Yamabe","year":"2020","journal-title":"Sci. Rep."},{"key":"2026080511082313200_cit13","unstructured":"Vediyappan, G.; Hua, D. H.\n          Sesquiterpenes\nfor Antifungal Applications. WO Patent WO2013013178A1, 2013."},{"key":"2026080511082313200_cit14","doi-asserted-by":"publisher","first-page":"112","DOI":"10.1039\/C2MD20127E","article-title":"Inhibitors\nof Bacterial Tubulin Target Bacterial Membranes in Vivo","volume":"4","author":"Foss","year":"2013","journal-title":"MedChemComm."},{"key":"2026080511082313200_cit15","doi-asserted-by":"publisher","first-page":"962","DOI":"10.1248\/bpb.19.962","article-title":"Anti-Tumor-Promoting Activities of\nTriterpenoids from Ferns. I","volume":"19","author":"Konoshima","year":"1996","journal-title":"Biol. Pharm. Bull."},{"key":"2026080511082313200_cit16","doi-asserted-by":"publisher","first-page":"14100","DOI":"10.1002\/chem.201202260","article-title":"Synthesis\nof 11-cis-Retinoids by Hydrosilylation-Protodesilylation of an 11,12-Didehydro\nPrecursor: Easy Access to 11- and 12-Mono- and 11,12-Dideuteroretinoids","volume":"18","author":"Bergueiro","year":"2012","journal-title":"Chem. Eur. J."},{"key":"2026080511082313200_cit17","doi-asserted-by":"publisher","first-page":"26080","DOI":"10.1002\/anie.202108037","article-title":"Asymmetric Cation-Olefin Monocyclization\nby Engineered Squalene-Hopene Cyclases","volume":"60","author":"Eichenberger","year":"2021","journal-title":"Angew.\nChem., Int. Ed."},{"key":"2026080511082313200_cit18","doi-asserted-by":"publisher","first-page":"5073","DOI":"10.1021\/acscatal.2c05949","article-title":"Alternative Active Site Confinement in Squalene-Hopene Cyclase Enforces\nSubstrate Preorganization for Cyclization","volume":"13","author":"Schell","year":"2023","journal-title":"ACS\nCatal."},{"key":"2026080511082313200_cit19","doi-asserted-by":"publisher","first-page":"6269","DOI":"10.1038\/s41467-022-34030-0","article-title":"Spheroplast\nPreparation Boosts the Catalytic Potential of a Squalene-hopene Cyclase","volume":"13","author":"Beni\u0301tez-Mateos","year":"2022","journal-title":"Nat. Commun."},{"key":"2026080511082313200_cit20","doi-asserted-by":"publisher","first-page":"13251","DOI":"10.1002\/anie.202101228","article-title":"Stereoselective\nDirected Cationic\nCascades Enabled by Molecular Anchoring in Terpene Cyclases","volume":"60","author":"Schneider","year":"2021","journal-title":"Angew. Chem., Int. Ed."},{"key":"2026080511082313200_cit21","doi-asserted-by":"publisher","first-page":"1501","DOI":"10.1126\/science.aaq0445","article-title":"Activation of Olefins via Asymmetric Br\u00f8nsted Acid Catalysis","volume":"359","author":"Tsuji","year":"2018","journal-title":"Science"},{"key":"2026080511082313200_cit22","doi-asserted-by":"publisher","first-page":"675","DOI":"10.1021\/jacs.0c12042","article-title":"Strong and Confined\nAcids Catalyze Asymmetric Intramolecular Hydroarylations of Unactivated\nOlefins with Indoles","volume":"143","author":"Zhang","year":"2021","journal-title":"J. Am. Chem. Soc."},{"key":"2026080511082313200_cit23","doi-asserted-by":"publisher","first-page":"8788","DOI":"10.1021\/jacs.3c01404","article-title":"A Catalytic\nAsymmetric Hydrolactonization","volume":"145","author":"Maji","year":"2023","journal-title":"J. Am. Chem.\nSoc."},{"key":"2026080511082313200_cit24","doi-asserted-by":"publisher","first-page":"1174","DOI":"10.1038\/s41557-020-00558-1","article-title":"Catalytic Enantiocontrol over a Nonclassical Carbocation","volume":"12","author":"Properzi","year":"2020","journal-title":"Nat. Chem."},{"key":"2026080511082313200_cit25","doi-asserted-by":"publisher","first-page":"287","DOI":"10.1038\/s41586-023-06826-7","article-title":"Catalytic Asymmetric\nCationic Shifts\nof Aliphatic Hydrocarbons","volume":"625","author":"Wakchaure","year":"2024","journal-title":"Nature"},{"key":"2026080511082313200_cit26","doi-asserted-by":"publisher","first-page":"795","DOI":"10.1038\/s41586-024-07757-7","article-title":"The Catalytic\nAsymmetric Polyene\nCyclization of Homofarnesol to Ambrox","volume":"632","author":"Luo","year":"2024","journal-title":"Nature"},{"key":"2026080511082313200_cit27","doi-asserted-by":"publisher","first-page":"813","DOI":"10.1038\/s41467-023-36157-0","article-title":"Enzyme-Like\nPolyene Cyclizations Catalyzed by Dynamic,\nSelf-Assembled, Supramolecular Fluoro Alcohol-Amine Clusters","volume":"14","author":"Arnold","year":"2023","journal-title":"Nat. Commun."},{"key":"2026080511082313200_cit28","doi-asserted-by":"publisher","first-page":"268","DOI":"10.1021\/acs.orglett.5b03438","article-title":"Tetraphenylphosphonium Tetrafluoroborate\/1,1,1,3,3,3-Hexafluoroisopropanol\n(Ph4PBF4\/HFIP) Effecting Epoxide-Initiated Cation-Olefin\nPolycyclizations","volume":"18","author":"Tian","year":"2016","journal-title":"Org. Lett."},{"key":"2026080511082313200_cit29","doi-asserted-by":"publisher","first-page":"8421","DOI":"10.1021\/ja0545463","article-title":"Unveiling\nthe \u201cBooster Effect\u201d of Fluorinated Alcohol Solvents:\nAggregation-Induced Conformational Changes and Cooperatively Enhanced\nH-Bonding","volume":"128","author":"Berkessel","year":"2006","journal-title":"J. Am. Chem. Soc."},{"key":"2026080511082313200_cit30","doi-asserted-by":"publisher","first-page":"0088","DOI":"10.1038\/s41570-017-0088","article-title":"Hexafluoroisopropanol\nas a Highly Versatile Solvent","volume":"1","author":"Colomer","year":"2017","journal-title":"Nat. Rev. Chem."},{"key":"2026080511082313200_cit31","doi-asserted-by":"publisher","first-page":"12544","DOI":"10.1021\/acs.chemrev.1c00749","article-title":"HFIP in Organic\nSynthesis","volume":"122","author":"Motiwala","year":"2022","journal-title":"Chem. Rev."},{"key":"2026080511082313200_cit32","doi-asserted-by":"publisher","first-page":"10125","DOI":"10.1021\/acs.orglett.9b04133","article-title":"Relative\nand Absolute Structure Assignments of Alkenes Using Crystalline Osmate\nDerivatives for X-ray Analysis","volume":"21","author":"Burns","year":"2019","journal-title":"Org. Lett."},{"key":"2026080511082313200_cit33","unstructured":"Schelwies, M.; Brunner, B.; Pelzer, R.; List, B.; Turberg, M.; Mitschke, B.; Das, S.; De, C. K.\n          Process for the Preparation\nof Cyclohomogeranates. WO Patent WO2023247609A1, 2023."},{"key":"2026080511082313200_cit34","doi-asserted-by":"publisher","first-page":"967","DOI":"10.1002\/1099-0690(200203)2002:6&lt;967::AID-EJOC967&gt;3.0.CO;2-E","article-title":"Optically Active Ionones\nand Derivatives: Preparation and Olfactory Properties","volume":"2002","author":"Brenna","year":"2002","journal-title":"Eur. J. Org. Chem."},{"key":"2026080511082313200_cit35","doi-asserted-by":"publisher","first-page":"2551","DOI":"10.1021\/ol049126h","article-title":"Tin(IV) Chloride-Chiral\nPyrogallol\nDerivatives as New Lewis Acid-Assisted Chiral Br\u00f8nsted Acids\nfor Enantioselective Polyene Cyclization","volume":"6","author":"Kumazawa","year":"2004","journal-title":"Org.\nLett."},{"key":"2026080511082313200_cit36","doi-asserted-by":"publisher","first-page":"11992","DOI":"10.1021\/ja305851h","article-title":"Highly Enantioselective\nProton-Initiated Polycyclization\nof Polyenes","volume":"134","author":"Surendra","year":"2012","journal-title":"J. Am. Chem. Soc."},{"key":"2026080511082313200_cit37","doi-asserted-by":"publisher","first-page":"1505","DOI":"10.1021\/ja003541x","article-title":"Enantioselective Biomimetic Cyclization\nof Homo(polyprenyl)arenes: A New Entry to (+)-Podocarpa-8,11,13-triene\nDiterpenoids and (\u2212)-Tetracyclic Polyprenoid of Sedimentary\nOrigin","volume":"123","author":"Ishihara","year":"2001","journal-title":"J. Am. Chem. Soc."},{"key":"2026080511082313200_cit38","doi-asserted-by":"publisher","first-page":"3414","DOI":"10.1021\/jacs.8b13899","article-title":"Strong and Confined Acids Enable\na Catalytic Asymmetric Nazarov Cyclization\nof Simple Divinyl Ketones","volume":"141","author":"Ouyang","year":"2019","journal-title":"J. Am. Chem. Soc."},{"key":"2026080511082313200_cit39","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202117366","article-title":"Hydrogen Bonding\nNetworks Enable Br\u00f8nsted Acid-Catalyzed Carbonyl-Olefin Metathesis","volume":"61","author":"Anh To","year":"2022","journal-title":"Angew. Chem., Int. Ed."},{"key":"2026080511082313200_cit40","doi-asserted-by":"publisher","first-page":"2028","DOI":"10.1002\/anie.201508983","article-title":"A Simple Graphical\nMethod to Determine the Order in Catalyst","volume":"55","author":"Bures","year":"2016","journal-title":"Angew.\nChem., Int. Ed."},{"key":"2026080511082313200_cit41","doi-asserted-by":"publisher","first-page":"348","DOI":"10.1039\/C8SC04698K","article-title":"Visual Kinetic Analysis","volume":"10","author":"Nielsen","year":"2019","journal-title":"Chem. Sci."},{"key":"2026080511082313200_cit42","doi-asserted-by":"publisher","first-page":"23481","DOI":"10.1021\/jacs.6c06916","article-title":"Catalytic Asymmetric\nHydration of\nAlkenes","volume":"148","author":"Hatano","year":"2026","journal-title":"J. Am. Chem. Soc."},{"key":"2026080511082313200_cit43","doi-asserted-by":"publisher","first-page":"10330","DOI":"10.1021\/ja073679g","article-title":"A Simple Method\nto Determine Kinetic Deuterium Isotope\nEffects Provides Evidence That Proton Transfer to Carbon Proceeds\nover and Not through the Reaction Barrier","volume":"129","author":"Tsang","year":"2007","journal-title":"J.\nAm. Chem. Soc."},{"key":"2026080511082313200_cit44","doi-asserted-by":"publisher","first-page":"855","DOI":"10.1021\/cs401190c","article-title":"Enantioselective Cascade Cyclization\/Protodemetalation\nof Polyenes with N3Pt2+ Catalysts","volume":"4","author":"Nguyen","year":"2014","journal-title":"ACS Catal."},{"key":"2026080511082313200_cit45","doi-asserted-by":"publisher","first-page":"11918","DOI":"10.1002\/chem.200901563","article-title":"Acid-Catalyzed\nCyclization of Terpenes under Homogeneous and Heterogeneous Conditions\nas Probed through Stereoisotopic Studies: A Concerted Process with\nCompeting Preorganized Chair and Boat Transition States","volume":"15","author":"Raptis","year":"2009","journal-title":"Chem. Eur. J."},{"key":"2026080511082313200_cit46","doi-asserted-by":"publisher","first-page":"10070","DOI":"10.1002\/anie.201701486","article-title":"Analyzing Reaction Rates with the Distortion\/Interaction-Activation\nStrain Model","volume":"56","author":"Bickelhaupt","year":"2017","journal-title":"Angew. Chem., Int. Ed."},{"key":"2026080511082313200_cit47","doi-asserted-by":"publisher","first-page":"539","DOI":"10.1002\/jcc.26812","article-title":"Independent Gradient\nModel Based on Hirshfeld Partition: A New Method\nfor Visual Study of Interactions in Chemical Systems","volume":"43","author":"Lu","year":"2022","journal-title":"J. Comput. Chem."},{"key":"2026080511082313200_cit48","doi-asserted-by":"publisher","first-page":"580","DOI":"10.1002\/jcc.22885","article-title":"Multiwfn: A Multifunctional Wavefunction Analyzer","volume":"33","author":"Lu","year":"2012","journal-title":"J. Comput. Chem."},{"key":"2026080511082313200_cit49","doi-asserted-by":"publisher","first-page":"082503","DOI":"10.1063\/5.0216272","article-title":"A Comprehensive\nElectron Wavefunction Analysis Toolbox for Chemists, Multiwfn","volume":"161","author":"Lu","year":"2024","journal-title":"J. Chem. Phys."},{"key":"2026080511082313200_cit50","doi-asserted-by":"publisher","first-page":"2512","DOI":"10.1039\/c3sc50571e","article-title":"C-H\u00b7\u00b7\u00b7\u03c0\nInteractions as Modulators\nof Carbocation Structure - Implications for Terpene Biosynthesis","volume":"4","author":"Hong","year":"2013","journal-title":"Chem. Sci."},{"key":"2026080511082313200_cit52","doi-asserted-by":"publisher","first-page":"13265","DOI":"10.1021\/ja074937c","article-title":"7,8-Dihydro\nRetinals Outperform the Native Retinals in Conferring Photosensitivity\nto Visual Opsin","volume":"129","author":"DeGrip","year":"2007","journal-title":"J. Am. Chem. Soc."},{"key":"2026080511082313200_cit53","doi-asserted-by":"publisher","first-page":"975","DOI":"10.1021\/np300230t","article-title":"Stereoselective\nSynthesis by Olefin\nMetathesis and Characterization of \u03b7-Carotene (7,8,7\u2019,8\u2019-Tetrahydro-\u03b2,\u03b2-Carotene)","volume":"75","author":"Fontan","year":"2012","journal-title":"J. Nat. Prod."},{"key":"2026080511082313200_cit54","unstructured":"Mueller, M. A.; Bonrath, W.; Wuestenberg, B.; Zimmermann, V.\n          New Process for\nthe Production of Retinal. WO Patent WO2020212164A1, 2020."}],"container-title":["Journal of\nthe American\nChemical Society"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/jacs.6c08353","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/jacsat\/article-pdf\/148\/30\/31649\/66067405\/jacs.6c08353.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/pubs.acs.org\/jacsat\/article-pdf\/148\/30\/31649\/66067405\/jacs.6c08353.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,5]],"date-time":"2026-08-05T15:23:24Z","timestamp":1785943404000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/jacsat\/article\/148\/30\/31649\/5222556\/Catalytic-Asymmetric-Cationic-Geranyl-Cyclizations"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7,20]]},"references-count":53,"journal-issue":{"issue":"30","published-online":{"date-parts":[[2026,7,20]]},"published-print":{"date-parts":[[2026,8,5]]}},"URL":"https:\/\/doi.org\/10.1021\/jacs.6c08353","relation":{},"ISSN":["0002-7863","1520-5126"],"issn-type":[{"value":"0002-7863","type":"print"},{"value":"1520-5126","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,7,20]]}}}