{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T17:17:21Z","timestamp":1788455841745,"version":"build-2803163510"},"reference-count":45,"publisher":"American Chemical Society (ACS)","issue":"34","license":[{"start":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T00:00:00Z","timestamp":1787184000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T00:00:00Z","timestamp":1787184000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T00:00:00Z","timestamp":1787184000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/100006151","name":"Basic Energy Sciences","doi-asserted-by":"publisher","award":["DE-SC0024991"],"award-info":[{"award-number":["DE-SC0024991"]}],"id":[{"id":"10.13039\/100006151","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,9,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Bridging atomically precise materials design with scalable membrane manufacturing remains a central challenge in separation science. Two-dimensional covalent organic frameworks (2D COFs) offer tunable porosity and chemistry, but poor crystallinity and processability have limited their performance in membranes. Here we demonstrate that incorporating single-crystalline 2D COFs into anodic aluminum oxide supports and scalable mixed-matrix membrane enables exceptional separation performance, achieving ultrahigh permeance (MMM-SC-0.6: 8764 and 4531 L m\u20132 h\u20131 bar\u20131 for hexane and methanol, respectively) and near-quantitative rejection of nanoscale solutes. Reactive force field simulations through a multilayer COF model reveal the origins of rapid solvent transport and size selectivity through steric gating. These results establish highly crystalline COFs as practical, high-performance membrane materials and point to new routes for energy-efficient separations across chemical, environmental, and industrial technologies.<\/jats:p>","DOI":"10.1021\/jacs.6c10184","type":"journal-article","created":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T15:03:14Z","timestamp":1787238194000},"page":"36997-37006","source":"Crossref","is-referenced-by-count":0,"title":["Membranes Incorporating\n2D Single-Crystalline COFs\nfor Superior Separation Performance: 3D Image-Informed Reactive Force\nField Modeling and Scalable Mixed-Matrix Systems"],"prefix":"10.1021","volume":"148","author":[{"given":"Jasasmita","family":"Das","sequence":"first","affiliation":[{"name":"University of Wyoming , , , ,","place":["Laramie, Wyoming, United States, 82071"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8198-001X","authenticated-orcid":true,"given":"Yun Kyung","family":"Shin","sequence":"additional","affiliation":[{"name":"Pennsylvania State University , , , ,","place":["University Park, Pennsylvania, United States, 16802"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beatrice","family":"Bartolomei","sequence":"additional","affiliation":[{"name":"Northwestern University , , , ,","place":["Evanston, Illinois, United States, 60208"]},{"name":"Max Planck Institute for Solid State Research , , ,","place":["Stuttgart, Germany, 70569"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caleb","family":"Johannesmeyer","sequence":"additional","affiliation":[{"name":"University of Wyoming , , , ,","place":["Laramie, Wyoming, United States, 82071"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3415-4732","authenticated-orcid":true,"given":"Gabriel T.","family":"dos Santos","sequence":"additional","affiliation":[{"name":"Northwestern University , , , ,","place":["Evanston, Illinois, United States, 60208"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1161-764X","authenticated-orcid":true,"given":"Michael L.","family":"Barsoum","sequence":"additional","affiliation":[{"name":"Northwestern University , , , ,","place":["Evanston, Illinois, United States, 60208"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6011-6078","authenticated-orcid":true,"given":"Roberto","family":"dos Reis","sequence":"additional","affiliation":[{"name":"Northwestern University , , , ,","place":["Evanston, Illinois, United States, 60208"]},{"name":"Northwestern University , , , ,","place":["Evanston, Illinois, United States, 60208"]},{"name":"Northwestern University , , , ,","place":["Evanston, Illinois, United States, 60208"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6007-3063","authenticated-orcid":true,"given":"Vinayak P.","family":"Dravid","sequence":"additional","affiliation":[{"name":"Northwestern University , , , ,","place":["Evanston, Illinois, United States, 60208"]},{"name":"Northwestern University , , , ,","place":["Evanston, Illinois, United States, 60208"]},{"name":"Northwestern University , , , ,","place":["Evanston, Illinois, United States, 60208"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3478-4945","authenticated-orcid":true,"given":"Adri C. 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Ed."}],"container-title":["Journal of the American\nChemical Society"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/jacs.6c10184","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/jacsat\/article-pdf\/148\/34\/36997\/66911894\/jacs.6c10184.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/pubs.acs.org\/jacsat\/article-pdf\/148\/34\/36997\/66911894\/jacs.6c10184.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T16:24:55Z","timestamp":1788452695000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/jacsat\/article\/148\/34\/36997\/5278443\/Membranes-Incorporating-2D-Single-Crystalline-COFs"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8,20]]},"references-count":45,"journal-issue":{"issue":"34","published-online":{"date-parts":[[2026,8,20]]},"published-print":{"date-parts":[[2026,9,2]]}},"URL":"https:\/\/doi.org\/10.1021\/jacs.6c10184","relation":{},"ISSN":["0002-7863","1520-5126"],"issn-type":[{"value":"0002-7863","type":"print"},{"value":"1520-5126","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,8,20]]}}}