{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T15:24:25Z","timestamp":1787153065344,"version":"build-2736575974"},"reference-count":46,"publisher":"American Chemical Society (ACS)","issue":"32","license":[{"start":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T00:00:00Z","timestamp":1785801600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100009024","name":"Exploratory Research for Advanced Technology","doi-asserted-by":"publisher","award":["JPMJER1903"],"award-info":[{"award-number":["JPMJER1903"]}],"id":[{"id":"10.13039\/501100009024","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/na","name":"JSPS Grants-in-Aid for Scientific Research","doi-asserted-by":"publisher","award":["22H02069"],"award-info":[{"award-number":["22H02069"]}],"id":[{"id":"10.13039\/na","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/na","name":"JSPS Grants-in-Aid for Scientific Research","doi-asserted-by":"publisher","award":["23K26647"],"award-info":[{"award-number":["23K26647"]}],"id":[{"id":"10.13039\/na","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/na","name":"JSPS Grants-in-Aid for Transformative Research Areas (A) Digi-TOS","doi-asserted-by":"publisher","award":["24H01045"],"award-info":[{"award-number":["24H01045"]}],"id":[{"id":"10.13039\/na","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/na","name":"JSPS Grants-in-Aid for Transformative Research Areas (A) Transformation of Carbon-Based Resources","doi-asserted-by":"publisher","award":["24H01830"],"award-info":[{"award-number":["24H01830"]}],"id":[{"id":"10.13039\/na","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/na","name":"JSPS Grants-in-Aid for Scientific Research","doi-asserted-by":"publisher","award":["25K08651"],"award-info":[{"award-number":["25K08651"]}],"id":[{"id":"10.13039\/na","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/na","name":"JSPS Grants-in-Aid for Transformative Research Areas (A) Transformation of Carbon-Based Resources","doi-asserted-by":"publisher","award":["26H00858"],"award-info":[{"award-number":["26H00858"]}],"id":[{"id":"10.13039\/na","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/na","name":"JSPS Grants-in-Aid for Scientific Research","doi-asserted-by":"publisher","award":["26K01493"],"award-info":[{"award-number":["26K01493"]}],"id":[{"id":"10.13039\/na","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/na","name":"Chugai Foundation for Innovative Drug Discovery Science","doi-asserted-by":"publisher","award":["NA"],"award-info":[{"award-number":["NA"]}],"id":[{"id":"10.13039\/na","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/na","name":"Institute for Chemical Reaction Design and Discovery (ICReDD), established by the World Premier International Research Initiative (WPI), MEXT, Japan","doi-asserted-by":"publisher","award":["NA"],"award-info":[{"award-number":["NA"]}],"id":[{"id":"10.13039\/na","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/na","name":"Regional R&D Proposal-Based Program from the Northern Advancement Center for Science & Technology of Hokkaido, Japan","doi-asserted-by":"publisher","award":["NA"],"award-info":[{"award-number":["NA"]}],"id":[{"id":"10.13039\/na","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,8,19]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Fluoroform is an ideal trifluoromethyl source in synthetic chemistry due to its low cost, low toxicity, and high potential for greenhouse-gas valorization. However, the use of fluoroform has been largely limited to the generation of trifluoromethyl anions or metal-bound species; direct access to the trifluoromethyl radical remains elusive, despite the broad applicability of radical trifluoromethylation for preparing medicinally important compounds. Here, we report a method for radical trifluoromethylation using fluoroform by leveraging the reactivity of ketones in combination with a Br\u00f8nsted base under photoirradiation. The ketone-mediated photochemical activation provides access to the trifluoromethyl radical from fluoroform via a photoexcited alkoxide intermediate without exogenous redox reagents, enabling radical trifluoromethylation of alkenes and arenes under mild conditions. The developed system is amenable to a photocatalytic protocol, late-stage trifluoromethylation of complex molecules, and upgrading bulk chemicals into high-value trifluoromethylated compounds.<\/jats:p>","DOI":"10.1021\/jacs.6c10939","type":"journal-article","created":{"date-parts":[[2026,8,5]],"date-time":"2026-08-05T00:01:51Z","timestamp":1785888111000},"page":"34907-34915","source":"Crossref","is-referenced-by-count":0,"title":["Photocatalytic Activation\nof Fluoroform for Radical\nTrifluoromethylation"],"prefix":"10.1021","volume":"148","author":[{"given":"Shun","family":"Zhou","sequence":"first","affiliation":[{"name":"Hokkaido University , , Kita 21, Nishi 10 , Kita-ku, , ,","place":["Sapporo, Hokkaido, Japan, 001-0021"]},{"name":"Hokkaido University , , Kita 10, Nishi 8 , Kita-ku, , ,","place":["Sapporo, Hokkaido, Japan, 060-0810"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Song","sequence":"additional","affiliation":[{"name":"Hokkaido University , , Kita 10, Nishi 8 , Kita-ku, , ,","place":["Sapporo, Hokkaido, Japan, 060-0810"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"Harabuchi","sequence":"additional","affiliation":[{"name":"Hokkaido University , , Kita 21, Nishi 10 , Kita-ku, , ,","place":["Sapporo, Hokkaido, Japan, 001-0021"]},{"name":"Hokkaido University , , Kita 10, Nishi 8 , Kita-ku, , ,","place":["Sapporo, Hokkaido, Japan, 060-0810"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2931-6661","authenticated-orcid":true,"given":"Wataru","family":"Kanna","sequence":"additional","affiliation":[{"name":"Hokkaido University , , Kita 10, Nishi 8 , Kita-ku, , ,","place":["Sapporo, Hokkaido, Japan, 060-0810"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hitomi","family":"Katsuyama","sequence":"additional","affiliation":[{"name":"Hokkaido University , , Kita 21, Nishi 10 , Kita-ku, , ,","place":["Sapporo, Hokkaido, Japan, 001-0021"]},{"name":"Hokkaido University , , Kita 10, Nishi 8 , Kita-ku, , ,","place":["Sapporo, Hokkaido, Japan, 060-0810"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1465-5879","authenticated-orcid":true,"given":"Simon J.","family":"Cooper","sequence":"additional","affiliation":[{"name":"Hokkaido University , , Kita 21, Nishi 10 , Kita-ku, , ,","place":["Sapporo, Hokkaido, Japan, 001-0021"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3591-5409","authenticated-orcid":true,"suffix":"III","given":"Kosaku","family":"Tanaka","sequence":"additional","affiliation":[{"name":"Hokkaido University , , Kita 21, Nishi 10 , Kita-ku, , ,","place":["Sapporo, Hokkaido, Japan, 001-0021"]},{"name":"Hokkaido University , , Kita 10, Nishi 8 , Kita-ku, , ,","place":["Sapporo, Hokkaido, Japan, 060-0810"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6655-3439","authenticated-orcid":true,"given":"Tsuyoshi","family":"Mita","sequence":"additional","affiliation":[{"name":"Hokkaido University , , Kita 21, Nishi 10 , Kita-ku, , ,","place":["Sapporo, Hokkaido, Japan, 001-0021"]},{"name":"Hokkaido University , , Kita 10, Nishi 8 , Kita-ku, , ,","place":["Sapporo, Hokkaido, Japan, 060-0810"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8822-1147","authenticated-orcid":true,"given":"Satoshi","family":"Maeda","sequence":"additional","affiliation":[{"name":"Hokkaido University , , Kita 21, Nishi 10 , Kita-ku, , ,","place":["Sapporo, Hokkaido, Japan, 001-0021"]},{"name":"Hokkaido University , , Kita 10, Nishi 8 , Kita-ku, , ,","place":["Sapporo, Hokkaido, Japan, 060-0810"]},{"name":"Hokkaido University , , Kita 10, Nishi 8 , Kita-ku, , ,","place":["Sapporo, Hokkaido, Japan, 060-0810"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2081-6886","authenticated-orcid":true,"given":"Hiroki","family":"Hayashi","sequence":"additional","affiliation":[{"name":"Hokkaido University , , Kita 21, Nishi 10 , Kita-ku, , ,","place":["Sapporo, Hokkaido, Japan, 001-0021"]},{"name":"Hokkaido University , , Kita 10, Nishi 8 , Kita-ku, , ,","place":["Sapporo, Hokkaido, Japan, 060-0810"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2026,8,4]]},"reference":[{"key":"2026081910242569300_cit1","doi-asserted-by":"publisher","first-page":"2","DOI":"10.1021\/jacs.5b08707","article-title":"Evolution\nof C\u2013H bond functionalization from methane to methodology","volume":"138","author":"Hartwig","year":"2016","journal-title":"J. Am. Chem. Soc."},{"key":"2026081910242569300_cit2","doi-asserted-by":"publisher","first-page":"668","DOI":"10.1126\/science.aat9750","article-title":"Selective functionalization\nof methane, ethane, and higher alkanes by cerium photocatalysis","volume":"361","author":"Hu","year":"2018","journal-title":"Science"},{"key":"2026081910242569300_cit3","doi-asserted-by":"publisher","first-page":"92","DOI":"10.1126\/science.abb4688","article-title":"C(sp3)\u2013H functionalizations of light hydrocarbons using decatungstate\nphotocatalysis in flow","volume":"369","author":"Laudadio","year":"2020","journal-title":"Science"},{"key":"2026081910242569300_cit4","doi-asserted-by":"publisher","first-page":"1881","DOI":"10.1126\/science.1131943","article-title":"Fluorine in\npharmaceuticals: Looking\nbeyond intuition","volume":"317","author":"Mu\u0308ller","year":"2007","journal-title":"Science"},{"key":"2026081910242569300_cit5","doi-asserted-by":"publisher","first-page":"8315","DOI":"10.1021\/acs.jmedchem.5b00258","article-title":"Applications\nof fluorine in medicinal chemistry","volume":"58","author":"Gillis","year":"2015","journal-title":"J. Med.\nChem."},{"key":"2026081910242569300_cit6","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1016\/j.jfluchem.2012.04.012","article-title":"Treatment of the potent greenhouse\ngas, CHF3\u2500An overview","volume":"140","author":"Han","year":"2012","journal-title":"J.\nFluor. Chem."},{"key":"2026081910242569300_cit7","unstructured":"United Nations Treaty Collection.\n          \n          United Nations\nEnvironment Programme. Amendment to the Montreal Protocol on substances\nthat deplete the ozone layer; https:\/\/treaties.un.org\/Pages\/ViewDetails.aspx?src=IND&mtdsg_no=XXVII-2-f&chapter=27&clang=_en. Accessed 30 April 2026."},{"key":"2026081910242569300_cit8","unstructured":"U.S. Environmental Protection Agency.\n          \n          Control of\nHFC-23 emissions; https:\/\/www.epa.gov\/climate-hfcs-reduction\/control-hfc-23-emissions. Accessed 30 April 2026."},{"issue":"1","key":"2026081910242569300_cit9","doi-asserted-by":"publisher","first-page":"397","DOI":"10.1038\/s41467-019-13899-4","article-title":"Increase in global emissions of HFC-23 despite near-total expected\nreductions","volume":"11","author":"Stanley","year":"2020","journal-title":"Nat. Commun."},{"key":"2026081910242569300_cit10","doi-asserted-by":"publisher","first-page":"5822","DOI":"10.1021\/acs.jmedchem.7b01788","article-title":"Fluorine\nand fluorinated motifs in the design and application of bioisosteres\nfor drug design","volume":"61","author":"Meanwell","year":"2018","journal-title":"J. Med. Chem."},{"key":"2026081910242569300_cit11","doi-asserted-by":"publisher","first-page":"101467","DOI":"10.1016\/j.isci.2020.101467","article-title":"Current contributions\nof organofluorine compounds to the agrochemical industry","volume":"23","author":"Ogawa","year":"2020","journal-title":"iScience"},{"key":"2026081910242569300_cit12","doi-asserted-by":"publisher","first-page":"110092","DOI":"10.1016\/j.jfluchem.2023.110092","article-title":"Using fluoroform in trifluoromethylation\nreactions","volume":"266","author":"Luo","year":"2023","journal-title":"J. Fluor. Chem."},{"key":"2026081910242569300_cit13","doi-asserted-by":"publisher","first-page":"3127","DOI":"10.1021\/ja00401a034","article-title":"Hydrogen isotope\nexchange between fluoroform (CF3H) and water. 1. Catalysis\nby hydroxide ion","volume":"103","author":"Symons","year":"1981","journal-title":"J. Am. Chem. Soc."},{"key":"2026081910242569300_cit14","doi-asserted-by":"publisher","first-page":"2","DOI":"10.1021\/jo00001a002","article-title":"Electroorganic\nchemistry. 130. A novel trifluoromethylation of aldehydes and ketones\npromoted by an electrogenerated base","volume":"56","author":"Shono","year":"1991","journal-title":"J. Org.\nChem."},{"key":"2026081910242569300_cit15","doi-asserted-by":"publisher","first-page":"1324","DOI":"10.1126\/science.1227859","article-title":"Taming of fluoroform:\nDirect nucleophilic trifluoromethylation of Si, B, S, and C centers","volume":"338","author":"Prakash","year":"2012","journal-title":"Science"},{"key":"2026081910242569300_cit16","doi-asserted-by":"publisher","first-page":"9811","DOI":"10.1021\/jacs.7b05408","article-title":"Recyclable trifluoromethylation reagents from fluoroform","volume":"139","author":"Geri","year":"2017","journal-title":"J. Am. Chem. Soc."},{"key":"2026081910242569300_cit17","doi-asserted-by":"publisher","first-page":"8950","DOI":"10.1002\/anie.201202624","article-title":"A \u201crenaissance\u201d\nin radical trifluoromethylation","volume":"51","author":"Studer","year":"2012","journal-title":"Angew. Chem.,\nInt. Ed."},{"key":"2026081910242569300_cit18","doi-asserted-by":"publisher","first-page":"6308","DOI":"10.1039\/D1CS00200G","article-title":"Radical trifluoromethylation","volume":"50","author":"Xiao","year":"2021","journal-title":"Chem. Soc. Rev."},{"key":"2026081910242569300_cit19","doi-asserted-by":"publisher","first-page":"1683","DOI":"10.1038\/s41557-023-01365-0","article-title":"Photocatalytic hydrofluoroalkylation of alkenes with\ncarboxylic acids","volume":"15","author":"Bian","year":"2023","journal-title":"Nat. Chem."},{"key":"2026081910242569300_cit20","doi-asserted-by":"publisher","first-page":"279","DOI":"10.1126\/science.adk4919","article-title":"Electrophotocatalytic\nperfluoroalkylation\nby LMCT excitation of Ag(II) perfluoroalkyl carboxylates","volume":"383","author":"Campbell","year":"2024","journal-title":"Science"},{"key":"2026081910242569300_cit21","doi-asserted-by":"publisher","first-page":"593","DOI":"10.1021\/j100874a507","article-title":"The C\u2013H bond dissociation\nenergy in fluoroform","volume":"70","author":"Amphlett","year":"1966","journal-title":"J. Phys. Chem."},{"key":"2026081910242569300_cit22","doi-asserted-by":"publisher","first-page":"255","DOI":"10.1021\/ar020230d","article-title":"Bond dissociation\nenergies of organic molecules","volume":"36","author":"Blanksby","year":"2003","journal-title":"Acc. Chem. Res."},{"key":"2026081910242569300_cit23","doi-asserted-by":"publisher","first-page":"968","DOI":"10.1021\/ja01210a017","article-title":"Fluorocarbon\nbromides","volume":"68","author":"Brice","year":"1946","journal-title":"J. Am. Chem. Soc."},{"key":"2026081910242569300_cit24","doi-asserted-by":"publisher","first-page":"147","DOI":"10.1002\/anie.198001471","article-title":"Heterogeneously catalyzed\ngas-phase bromination of trifluoromethane","volume":"19","author":"Bock","year":"1980","journal-title":"Angew.\nChem., Int. Ed."},{"key":"2026081910242569300_cit25","doi-asserted-by":"publisher","first-page":"20901","DOI":"10.1021\/ja2081026","article-title":"Direct cupration of fluoroform","volume":"133","author":"Zanardi","year":"2011","journal-title":"J. Am. Chem. Soc."},{"key":"2026081910242569300_cit26","doi-asserted-by":"publisher","first-page":"2446","DOI":"10.1021\/acs.orglett.7b01085","article-title":"Hydroxytrifluoromethylation of alkenes using fluoroform-derived\nCuCF3","volume":"19","author":"Yang","year":"2017","journal-title":"Org. Lett."},{"key":"2026081910242569300_cit27","doi-asserted-by":"publisher","first-page":"10320","DOI":"10.1002\/anie.201905782","article-title":"Argentination of\nfluoroform: Preparation of a stable AgCF3 solution with\ndiverse reactivities","volume":"58","author":"Xiang","year":"2019","journal-title":"Angew. Chem., Int. Ed."},{"key":"2026081910242569300_cit28","doi-asserted-by":"publisher","first-page":"577","DOI":"10.6023\/A23040127","article-title":"Hydrotrifluoromethylation\nof alkenes\nwith a fluoroform-derived trifluoromethylboron Complex","volume":"81","author":"Li","year":"2023","journal-title":"Acta Chim. Sinica"},{"key":"2026081910242569300_cit29","doi-asserted-by":"publisher","first-page":"13582","DOI":"10.1021\/acs.joc.9b01858","article-title":"Triplet-state\nstructures, energies, and antiaromaticity of BN analogues of benzene\nand their benzo-fused derivatives","volume":"84","author":"Baranac-Stojanovic\u0301","year":"2019","journal-title":"J. Org. Chem."},{"key":"2026081910242569300_cit30","doi-asserted-by":"publisher","first-page":"253","DOI":"10.1016\/1010-6030(89)80012-7","article-title":"Light-induced polymer\nand polymerization reactions\nXXXIII: Direct photoinitiation of methyl methacrylate polymerization\nby excited states of ketones","volume":"46","author":"Timpe","year":"1989","journal-title":"J. Photochem.\nPhotobiol., A"},{"key":"2026081910242569300_cit31","doi-asserted-by":"publisher","first-page":"7764","DOI":"10.1021\/ja00311a091","article-title":"Oxidation and reduction potentials of transient free\nradicals","volume":"107","author":"Wayner","year":"1985","journal-title":"J. Am. Chem. Soc."},{"key":"2026081910242569300_cit32","doi-asserted-by":"publisher","first-page":"224","DOI":"10.1038\/nature10647","article-title":"Trifluoromethylation\nof arenes and heteroarenes by\nmeans of photoredox catalysis","volume":"480","author":"Nagib","year":"2011","journal-title":"Nature"},{"key":"2026081910242569300_cit33","doi-asserted-by":"publisher","first-page":"14411","DOI":"10.1073\/pnas.1109059108","article-title":"Innate C\u2013H trifluoromethylation\nof heterocycles","volume":"108","author":"Ji","year":"2011","journal-title":"Proc. Natl. Acad. Sci. U. S.\nA."},{"issue":"20","key":"2026081910242569300_cit34","doi-asserted-by":"publisher","first-page":"7703","DOI":"10.1039\/C8CS00117K","article-title":"Catalysis for the synthesis of methacrylic acid and\nmethyl methacrylate","volume":"47","author":"Darabi Mahboub","year":"2018","journal-title":"Chem. Soc. Rev."},{"key":"2026081910242569300_cit35","doi-asserted-by":"publisher","first-page":"757","DOI":"10.1002\/chir.22209","article-title":"Design and synthesis\nof fluoroacylshikonin as an anticancer agent","volume":"25","author":"Kong","year":"2013","journal-title":"Chirality"},{"key":"2026081910242569300_cit36","doi-asserted-by":"publisher","first-page":"248","DOI":"10.1016\/j.canlet.2019.04.033","article-title":"Shikonin derivatives\nfor cancer prevention and therapy","volume":"459","author":"Boulos","year":"2019","journal-title":"Cancer Lett."},{"key":"2026081910242569300_cit37","unstructured":"Jacobs, R. T.; Yee, Y. K.; Bernstain, P. R.; Brewster, A. G.; Sependa, G. J.\n          A process for the\npreparation of 2(R)-methyl-4,4,4-trifluorobutylamine, intermediates,\nand a process for the preparation of a derivative thereof; EP 0,489,548\nA1, 1992."},{"key":"2026081910242569300_cit38","doi-asserted-by":"publisher","first-page":"1282","DOI":"10.1021\/jm00035a008","article-title":"Synthesis, structure-activity\nrelationships, and pharmacological evaluation of a series of fluorinated\n3-benzyl-5-indolecarboxamides: Identification of 4-[[5-[((2R)-2-methyl-4,4,4-trifluorobutyl)carbamoyl]-1-methylindol-3-yl]methyl]-3-methoxy-N-[(2-methylphenyl)sulfonyl]benzamide, a potent, orally\nactive antagonist of leukotrienes D4 and E4","volume":"37","author":"Jacobs","year":"1994","journal-title":"J. Med. Chem."},{"key":"2026081910242569300_cit39","unstructured":"Kreft, A.; Resnick, L.; Mayer, S.; Diamantidis, G.; Cole, D.; Harrison, B.; Zhang, M.; Hoke, M.; Wang, T.; Galante, R.\n          Fluoro- and\ntrifluoroalkyl-containing heterocyclic sulfonamide inhibitors of beta\namyloid production and derivatives thereof; US 2,004,019,8778\nA1, 2004."},{"key":"2026081910242569300_cit40","doi-asserted-by":"publisher","first-page":"6440","DOI":"10.1016\/j.tet.2008.04.072","article-title":"Practical asymmetric synthesis of a novel \u03b3-secretase\ninhibitor","volume":"64","author":"Wang","year":"2008","journal-title":"Tetrahedron"},{"key":"2026081910242569300_cit41","doi-asserted-by":"publisher","first-page":"2873","DOI":"10.1021\/jo982494c","article-title":"Cesium fluoride\ncatalyzed trifluoromethylation of esters, aldehydes, and ketones with\n(trifluoromethyl)trimethylsilane","volume":"64","author":"Singh","year":"1999","journal-title":"J. Org. Chem."},{"key":"2026081910242569300_cit42","doi-asserted-by":"publisher","first-page":"5237","DOI":"10.1039\/D1OB00221J","article-title":"Thioxanthone:\nA powerful photocatalyst\nfor organic reactions","volume":"19","author":"Nikitas","year":"2021","journal-title":"Org. Biomol. Chem."},{"key":"2026081910242569300_cit43","doi-asserted-by":"publisher","first-page":"1345","DOI":"10.1021\/ja01084a033","article-title":"Methylsulfinyl\ncarbanion (CH3\u2013SO\u2013CH2\u2013). Formation and applications to organic\nsynthesis","volume":"87","author":"Corey","year":"1965","journal-title":"J. Am. Chem. Soc."},{"key":"2026081910242569300_cit44","doi-asserted-by":"publisher","first-page":"8325","DOI":"10.1021\/acs.joc.7b00822","article-title":"Initiation in photoredox\nC\u2013H functionalization feactions. Is dimsyl anion a key ingredient?","volume":"82","author":"Bude\u0301n","year":"2017","journal-title":"J. Org. Chem."},{"key":"2026081910242569300_cit45","doi-asserted-by":"publisher","first-page":"20661","DOI":"10.1021\/jacs.0c08532","article-title":"Electroreductive carbofunctionalization of alkenes with alkyl bromides\nvia a radical-polar crossover mechanism","volume":"142","author":"Zhang","year":"2020","journal-title":"J.\nAm. Chem. Soc."},{"key":"2026081910242569300_cit46","doi-asserted-by":"publisher","first-page":"1278","DOI":"10.1126\/science.ady2969","article-title":"Trifluoromethylation of alkyl electrophiles with 11C-\nor 18F-labeled fluoroform for PET applications","volume":"390","author":"Wang","year":"2025","journal-title":"Science"}],"container-title":["Journal of the American\nChemical Society"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/jacs.6c10939","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/jacsat\/article-pdf\/148\/32\/34907\/66394518\/jacs.6c10939.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/pubs.acs.org\/jacsat\/article-pdf\/148\/32\/34907\/66394518\/jacs.6c10939.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T14:25:24Z","timestamp":1787149524000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/jacsat\/article\/148\/32\/34907\/5243706\/Photocatalytic-Activation-of-Fluoroform-for"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8,4]]},"references-count":46,"journal-issue":{"issue":"32","published-online":{"date-parts":[[2026,8,4]]},"published-print":{"date-parts":[[2026,8,19]]}},"URL":"https:\/\/doi.org\/10.1021\/jacs.6c10939","relation":{"has-preprint":[{"id-type":"doi","id":"10.26434\/chemrxiv.15000072\/v1","asserted-by":"object"}]},"ISSN":["0002-7863","1520-5126"],"issn-type":[{"value":"0002-7863","type":"print"},{"value":"1520-5126","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,8,4]]}}}