{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T20:00:23Z","timestamp":1789070423465,"version":"build-2803163510"},"reference-count":63,"publisher":"American Chemical Society (ACS)","issue":"30","license":[{"start":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T00:00:00Z","timestamp":1784764800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T00:00:00Z","timestamp":1784764800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T00:00:00Z","timestamp":1784764800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["22501274"],"award-info":[{"award-number":["22501274"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["51988102"],"award-info":[{"award-number":["51988102"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,8,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Enzyme-mimetic catalysis is widely recognized as an effective approach to developing high-performance catalysts. However, in many reactions conducted under conditions far from physiological, designs based on conventional enzymes often limit both activity and robustness. Inspired by hyperthermophilic enzymes that maintain high activity at temperatures nearing 100 \u00b0C, we propose an \u201cextremozymes-inspired\u201d design strategy and construct a hexameric aluminum porphyrin catalyst featuring a dimer-of-trimers architecture. By leveraging the geometric constraints imposed by covalent and noncovalent interactions between porphyrins, the catalyst forms two trigonal-pyramidal cavities, thereby replicating both the stable spatial arrangement and the confined multisite catalytic microenvironment characteristic of extremozymes. In propylene oxide (PO) homopolymerization and its copolymerizations with phthalic anhydride (PA) and carbon dioxide (CO2), respectively, the extremozymes-mimetic catalyst achieves record-high turnover frequencies (TOFs) while producing polymers with high number-average molecular weights (Mn) at ppm-level loadings: PO homopolymerization (TOF = 8.1 \u00d7 105 h\u20131, Mn = 1210 kg\/mol); PO\/PA copolymerization (TOF = 1.4 \u00d7 104 h\u20131, Mn = 140.8 kg\/mol); and PO\/CO2 copolymerization (TOF = 1.2 \u00d7 105 h\u20131, Mn = 802.3 kg\/mol). This study demonstrates the potential of using extremozymes as templates to develop high-performance catalysts and offers new insights into the design of biomimetic catalysts.<\/jats:p>","DOI":"10.1021\/jacs.6c11991","type":"journal-article","created":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T05:52:42Z","timestamp":1784785962000},"page":"32881-32893","source":"Crossref","is-referenced-by-count":1,"title":["Extremozymes-Inspired\nCatalyst for Epoxide-Based Polymerization"],"prefix":"10.1021","volume":"148","author":[{"given":"Liehang","family":"Yang","sequence":"first","affiliation":[{"name":"Chinese Academy of Sciences , , No.5625, Renmin Street , , ,","place":["Changchun, Jilin, P. R. China, 130022"]},{"name":"University of Science and Technology of China , , No.96, JinZhai Road , , ,","place":["Hefei, Anhui, P. R. China, 230026"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5514-0738","authenticated-orcid":true,"given":"Shunjie","family":"Liu","sequence":"additional","affiliation":[{"name":"Chinese Academy of Sciences , , No.5625, Renmin Street , , ,","place":["Changchun, Jilin, P. R. China, 130022"]},{"name":"University of Science and Technology of China , , No.96, JinZhai Road , , ,","place":["Hefei, Anhui, P. R. China, 230026"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hong","family":"Chen","sequence":"additional","affiliation":[{"name":"Chinese Academy of Sciences , , No.5625, Renmin Street , , ,","place":["Changchun, Jilin, P. R. China, 130022"]},{"name":"University of Science and Technology of China , , No.96, JinZhai Road , , ,","place":["Hefei, Anhui, P. R. China, 230026"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruoyu","family":"Zhang","sequence":"additional","affiliation":[{"name":"Chinese Academy of Sciences , , No.5625, Renmin Street , , ,","place":["Changchun, Jilin, P. R. China, 130022"]},{"name":"University of Science and Technology of China , , No.96, JinZhai Road , , ,","place":["Hefei, Anhui, P. R. China, 230026"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chunwei","family":"Zhuo","sequence":"additional","affiliation":[{"name":"Chinese Academy of Sciences , , No.5625, Renmin Street , , ,","place":["Changchun, Jilin, P. R. China, 130022"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3542-9256","authenticated-orcid":true,"given":"Xuesi","family":"Chen","sequence":"additional","affiliation":[{"name":"Chinese Academy of Sciences , , No.5625, Renmin Street , , ,","place":["Changchun, Jilin, P. R. China, 130022"]},{"name":"University of Science and Technology of China , , No.96, JinZhai Road , , ,","place":["Hefei, Anhui, P. R. China, 230026"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4228-705X","authenticated-orcid":true,"given":"Xianhong","family":"Wang","sequence":"additional","affiliation":[{"name":"Chinese Academy of Sciences , , No.5625, Renmin Street , , ,","place":["Changchun, Jilin, P. R. China, 130022"]},{"name":"University of Science and Technology of China , , No.96, JinZhai Road , , ,","place":["Hefei, Anhui, P. R. China, 230026"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2026,7,23]]},"reference":[{"issue":"1","key":"2026080511144821900_cit1","doi-asserted-by":"publisher","DOI":"10.1038\/s41570-018-0147","article-title":"Homogeneous\nCatalysis: Synthetic Models Close in on Enzymes","volume":"2","author":"Schilter","year":"2018","journal-title":"Nat. Rev. Chem."},{"issue":"18","key":"2026080511144821900_cit2","doi-asserted-by":"publisher","first-page":"11883","DOI":"10.1021\/acscatal.3c00320","article-title":"Bioinspired Catalyst\nDesign Principles: Progress in Emulating Properties of Enzymes in\nSynthetic Catalysts","volume":"13","author":"Ginovska","year":"2023","journal-title":"ACS Catal."},{"issue":"3","key":"2026080511144821900_cit3","doi-asserted-by":"publisher","first-page":"184","DOI":"10.1038\/s41929-020-0435-z","article-title":"Synergistic\nCatalysis in an Artificial Enzyme","volume":"3","author":"Ren","year":"2020","journal-title":"Nat. Catal."},{"issue":"8","key":"2026080511144821900_cit4","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202214665","article-title":"Bio-Inspired Bimetallic Cooperativity\nThrough a Hydrogen Bonding Spacer in CO2 Reduction","volume":"62","author":"Zhang","year":"2023","journal-title":"Angew. Chem., Int. Ed."},{"issue":"1","key":"2026080511144821900_cit5","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-020-16714-7","article-title":"A Host\u2013Guest\nApproach to Combining Enzymatic and Artificial Catalysis for Catalyzing\nBiomimetic Monooxygenation","volume":"11","author":"Zhao","year":"2020","journal-title":"Nat. Commun."},{"issue":"40","key":"2026080511144821900_cit6","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.add5678","article-title":"Creating Enzyme-Mimicking\nNanopockets in Metal-Organic Frameworks for Catalysis","volume":"8","author":"Zhang","year":"2022","journal-title":"Sci. Adv."},{"issue":"2","key":"2026080511144821900_cit7","doi-asserted-by":"publisher","first-page":"433","DOI":"10.1039\/C4CS00192C","article-title":"Transition\nMetal Catalysis in Confined Spaces","volume":"44","author":"Leenders","year":"2015","journal-title":"Chem. Soc.\nRev."},{"issue":"1","key":"2026080511144821900_cit8","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-022-32454-2","article-title":"Hydrogen-Bonded Organic Framework Biomimetic Entrapment\nAllowing Non-Native Biocatalytic Activity in Enzyme","volume":"13","author":"Chen","year":"2022","journal-title":"Nat. Commun."},{"issue":"5","key":"2026080511144821900_cit9","doi-asserted-by":"publisher","first-page":"537","DOI":"10.1038\/s44160-025-00799-3","article-title":"Allosteric Regulation in Metal\u2013Organic\nCages","volume":"4","author":"Yang","year":"2025","journal-title":"Nat. Synth."},{"issue":"15","key":"2026080511144821900_cit10","doi-asserted-by":"publisher","first-page":"13008","DOI":"10.1021\/jacs.5c03074","article-title":"Asymmetric\nCascade Photocycloaddition-Acyloin Rearrangement Enabled by Cage-Confined\nVisible-Light Catalysis","volume":"147","author":"Chen","year":"2025","journal-title":"J. Am. Chem. Soc."},{"issue":"46","key":"2026080511144821900_cit11","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202410881","article-title":"A Dual-Focus\nWorkflow for Simultaneously Engineering High Activity and Thermal\nStability in Methyl Parathion Hydrolase","volume":"63","author":"Li","year":"2024","journal-title":"Angew.\nChem., Int. Ed."},{"issue":"11","key":"2026080511144821900_cit12","doi-asserted-by":"publisher","first-page":"1173","DOI":"10.1016\/j.tibtech.2021.01.002","article-title":"Enzyme Catalyst Engineering toward the Integration\nof Biocatalysis and Chemocatalysis","volume":"39","author":"Cao","year":"2021","journal-title":"Trends Biotechnol."},{"issue":"2","key":"2026080511144821900_cit13","doi-asserted-by":"publisher","first-page":"144","DOI":"10.1016\/S1367-5931(00)00183-6","article-title":"Enzymes from Extremophiles","volume":"5","author":"Demirjian","year":"2001","journal-title":"Curr. Opin. Chem. Biol."},{"issue":"7","key":"2026080511144821900_cit14","doi-asserted-by":"publisher","first-page":"662","DOI":"10.1038\/nbt0795-662","article-title":"Extremozymes: Expanding\nthe Limits\nof Biocatalysis","volume":"13","author":"Adams","year":"1995","journal-title":"Bio\/Technology"},{"issue":"3","key":"2026080511144821900_cit15","doi-asserted-by":"publisher","first-page":"915","DOI":"10.1007\/s43393-025-00352-5","article-title":"Extremozymes: Unlocking\nPotential of Extreme Environments\nfor Sustainable Biotechnology","volume":"5","author":"Kour","year":"2025","journal-title":"Syst. Microbiol.\nBiomanuf."},{"key":"2026080511144821900_cit16","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1007\/BFb0102289","article-title":"Proteins\nfrom Hyperthermophiles: Stability and Enzymatic Catalysis Close to\nthe Boiling Point of Water","volume-title":"Biotechnology\nof Extremophiles","author":"Ladenstein","year":"1998"},{"issue":"2","key":"2026080511144821900_cit17","doi-asserted-by":"publisher","DOI":"10.1007\/s00792-025-01395-1","article-title":"Structural Insight into the Unique\nSubstrate Specificity of Glutamate Dehydrogenase from Saccharolobus\nsolfataricus","volume":"29","author":"Okabe","year":"2025","journal-title":"Extremophiles"},{"issue":"6","key":"2026080511144821900_cit18","doi-asserted-by":"publisher","first-page":"279","DOI":"10.1089\/ind.2024.0029","article-title":"Extremophiles and Related\nExtremozymes:\nTheir Structure-Function Relationship in Industrial Applications","volume":"20","author":"Kumari","year":"2024","journal-title":"Ind. Biotechnol."},{"issue":"2","key":"2026080511144821900_cit19","doi-asserted-by":"publisher","first-page":"325","DOI":"10.1016\/j.jmb.2004.10.063","article-title":"The First Crystal Structure\nof Hyperthermostable NAD-Dependent Glutamate\nDehydrogenase from Pyrobaculum islandicum","volume":"345","author":"Bhuiya","year":"2005","journal-title":"J.\nMol. Biol."},{"issue":"8","key":"2026080511144821900_cit20","doi-asserted-by":"publisher","first-page":"4031","DOI":"10.1021\/cg300503p","article-title":"A Series of Polymorphs\nof Hexakis(4-fluorophenoxy)cyclotriphosphazene","volume":"12","author":"Wahl","year":"2012","journal-title":"Cryst. Growth Des."},{"issue":"5","key":"2026080511144821900_cit21","doi-asserted-by":"publisher","first-page":"1377","DOI":"10.1002\/macp.1978.021790529","article-title":"Polymerization of 1,2-Epoxypropane\nand Copolymerization with Carbon\nDioxide Catalyzed by Metalloporphyrins","volume":"179","author":"Takeda","year":"1978","journal-title":"Makromol.\nChem."},{"issue":"2","key":"2026080511144821900_cit22","doi-asserted-by":"publisher","first-page":"376","DOI":"10.1016\/j.chemphys.2005.11.015","article-title":"The J- and H-Bands of Organic Dye\nAggregates","volume":"324","author":"Eisfeld","year":"2006","journal-title":"Chem. Phys."},{"issue":"35","key":"2026080511144821900_cit23","doi-asserted-by":"publisher","DOI":"10.1002\/chem.202401284","article-title":"A Bis-Porphyrin Cavitand Breathing-In\nto Constrict\nBucky Balls","volume":"30","author":"Kumari","year":"2024","journal-title":"Chem. -Eur. J."},{"issue":"1","key":"2026080511144821900_cit24","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1128\/MMBR.65.1.1-43.2001","article-title":"Hyperthermophilic Enzymes: Sources,\nUses, and Molecular\nMechanisms for Thermostability","volume":"65","author":"Vieille","year":"2001","journal-title":"Microbiol. Mol.\nBiol. Rev."},{"issue":"43","key":"2026080511144821900_cit25","doi-asserted-by":"publisher","first-page":"11054","DOI":"10.1021\/ja9815632","article-title":"Hexakis Porphyrinato\nBenzenes. A New Class of Porphyrin\nArrays","volume":"120","author":"Biemans","year":"1998","journal-title":"J. Am. Chem. Soc."},{"issue":"14","key":"2026080511144821900_cit26","doi-asserted-by":"publisher","first-page":"7907","DOI":"10.1021\/acs.inorgchem.7b00612","article-title":"Mixed-Substituent Cyclophosphazenes\nwith Calamitic and Polycatenar\nMesogens","volume":"56","author":"Jime\u0301nez","year":"2017","journal-title":"Inorg. Chem."},{"issue":"1","key":"2026080511144821900_cit27","doi-asserted-by":"publisher","first-page":"18","DOI":"10.1073\/pnas.74.1.18","article-title":"Synthesis and Characterization\nof \u201cFace-to-Face\u201d Porphyrins","volume":"74","author":"Collman","year":"1977","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"issue":"2","key":"2026080511144821900_cit28","doi-asserted-by":"publisher","first-page":"145","DOI":"10.1080\/00268976100100191","article-title":"The Proton\nMagnetic Resonance Spectra of Porphyrins","volume":"4","author":"Abraham","year":"1961","journal-title":"Mol.\nPhys."},{"issue":"3502","key":"2026080511144821900_cit29","doi-asserted-by":"publisher","first-page":"1009","DOI":"10.1038\/1381009a0","article-title":"Spectral\nAbsorption and Fluorescence of Dyes in the Molecular State","volume":"138","author":"Jelley","year":"1936","journal-title":"Nature"},{"issue":"31","key":"2026080511144821900_cit30","doi-asserted-by":"publisher","first-page":"7494","DOI":"10.1021\/ja000738g","article-title":"Factors Influencing Self-Aggregation\nTendencies of\nCationic Porphyrins in Aqueous Solution","volume":"122","author":"Kano","year":"2000","journal-title":"J.\nAm. Chem. Soc."},{"issue":"1","key":"2026080511144821900_cit31","doi-asserted-by":"publisher","first-page":"245","DOI":"10.1021\/ja510267c","article-title":"Multiporphyrin Arrays\nwith \u03c0\u2013\u03c0 Interchromophore Interactions","volume":"137","author":"Terazono","year":"2015","journal-title":"J. Am. Chem. Soc."},{"issue":"25","key":"2026080511144821900_cit32","doi-asserted-by":"publisher","first-page":"7783","DOI":"10.1021\/ja00311a105","article-title":"Properties\nof Porphyrin Dimers, Formed\nby Pairing Cationic and Anionic Porphyrins","volume":"107","author":"Ojadi","year":"1985","journal-title":"J. Am. Chem. Soc."},{"key":"2026080511144821900_cit33","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/B978-1-4831-9824-8.50007-4","article-title":"The Molecular\nExciton Model","volume-title":"Physical Processes in Radiation\nBiology","author":"McRae","year":"1964"},{"issue":"13","key":"2026080511144821900_cit34","doi-asserted-by":"publisher","first-page":"5185","DOI":"10.1002\/anie.201914966","article-title":"Living Supramolecular Polymerization\nof an Aza-BODIPY Dye Controlled\nby a Hydrogen-Bond-Accepting Triazole Unit Introduced by Click Chemistry","volume":"59","author":"Wang","year":"2020","journal-title":"Angew. Chem., Int. Ed."},{"issue":"43","key":"2026080511144821900_cit35","doi-asserted-by":"publisher","first-page":"37406","DOI":"10.1074\/jbc.M111.260265","article-title":"Structural\nBasis for Leucine-Induced\nAllosteric Activation of Glutamate Dehydrogenase","volume":"286","author":"Tomita","year":"2011","journal-title":"J. Biol. Chem."},{"issue":"20","key":"2026080511144821900_cit36","doi-asserted-by":"publisher","first-page":"9081","DOI":"10.1021\/acs.macromol.2c01596","article-title":"Rational\nOptimization of Bifunctional Organoboron Catalysts for Versatile\nPolyethers via Ring-Opening Polymerization of Epoxides","volume":"55","author":"Qi","year":"2022","journal-title":"Macromolecules"},{"issue":"39","key":"2026080511144821900_cit37","doi-asserted-by":"publisher","first-page":"16910","DOI":"10.1002\/anie.202002815","article-title":"High-Activity Organocatalysts\nfor Polyether Synthesis via Intramolecular Ammonium Cation Assisted\nSN2 Ring-Opening Polymerization","volume":"59","author":"Yang","year":"2020","journal-title":"Angew. Chem.,\nInt. Ed."},{"issue":"21","key":"2026080511144821900_cit38","doi-asserted-by":"publisher","first-page":"4678","DOI":"10.1021\/ja01075a031","article-title":"A Study of the Polymerization of\nPropylene Oxide Catalyzed by Anhydrous Potassium Hydroxide","volume":"86","author":"Steiner","year":"1964","journal-title":"J. Am. Chem. Soc."},{"issue":"18","key":"2026080511144821900_cit39","doi-asserted-by":"publisher","first-page":"6790","DOI":"10.1021\/acs.macromol.6b01363","article-title":"Sequential DMC\/FAB-Catalyzed\nAlkoxylation toward High\nPrimary Hydroxyl, High Molecular Weight Polyether Polyols","volume":"49","author":"Raghuraman","year":"2016","journal-title":"Macromolecules"},{"issue":"5","key":"2026080511144821900_cit40","doi-asserted-by":"publisher","first-page":"1777","DOI":"10.1021\/acs.macromol.7b02091","article-title":"Demystifying the\nMechanism of Regio- and Isoselective\nEpoxide Polymerization Using the Vandenberg Catalyst","volume":"51","author":"Ferrier","year":"2018","journal-title":"Macromolecules"},{"issue":"30","key":"2026080511144821900_cit41","doi-asserted-by":"publisher","first-page":"6459","DOI":"10.1039\/C4CC10113H","article-title":"Ring-Opening\nCopolymerization (ROCOP): Synthesis and Properties of Polyesters and\nPolycarbonates","volume":"51","author":"Paul","year":"2015","journal-title":"Chem. Commun."},{"issue":"24","key":"2026080511144821900_cit42","doi-asserted-by":"publisher","first-page":"15167","DOI":"10.1021\/acs.chemrev.6b00553","article-title":"Ring-Opening\nCopolymerization of\nEpoxides and Cyclic Anhydrides with Discrete Metal Complexes: Structure\u2013Property\nRelationships","volume":"116","author":"Longo","year":"2016","journal-title":"Chem. Rev."},{"issue":"6","key":"2026080511144821900_cit43","doi-asserted-by":"publisher","first-page":"803","DOI":"10.1002\/pol.20190175","article-title":"Phosphazene\/Lewis Acids\nas Highly Efficient Cooperative Catalyst for Synthesis of High-Molecular-Weight\nPolyesters by Ring-Opening Alternating Copolymerization of Epoxide\nand Anhydride","volume":"58","author":"Zhang","year":"2020","journal-title":"J. Polym. Sci."},{"issue":"14","key":"2026080511144821900_cit44","doi-asserted-by":"publisher","first-page":"12115","DOI":"10.1021\/jacs.5c00426","article-title":"Record-High-Molecular-Weight\nPolyesters from Ring-Opening Copolymerization\nof Epoxides and Cyclic Anhydrides Catalyzed by Hydrogen-Bond-Functionalized\nImidazoles","volume":"147","author":"Xie","year":"2025","journal-title":"J. Am. Chem. Soc."},{"issue":"2","key":"2026080511144821900_cit45","doi-asserted-by":"publisher","first-page":"713","DOI":"10.1021\/acs.macromol.0c02389","article-title":"Alkali Metal Carboxylates: Simple and Versatile Initiators for Ring-Opening\nAlternating Copolymerization of Cyclic Anhydrides\/Epoxides","volume":"54","author":"Chen","year":"2021","journal-title":"Macromolecules"},{"key":"2026080511144821900_cit46","doi-asserted-by":"publisher","first-page":"1787","DOI":"10.3762\/bjoc.10.187","article-title":"Copolymerization\nand Terpolymerization of Carbon Dioxide\/Propylene Oxide\/Phthalic Anhydride\nUsing a (Salen)Co(III) Complex Tethering Four Quaternary Ammonium\nSalts","volume":"10","author":"Jeon","year":"2014","journal-title":"Beilstein J. Org. Chem."},{"key":"2026080511144821900_cit47","doi-asserted-by":"publisher","first-page":"251","DOI":"10.1038\/s44160-025-00923-3","article-title":"Air-Stable\nCovalent Borane\u2013Oxyanion Organocatalysts for Ring-Opening Copolymerization","volume":"5","author":"Feng","year":"2026","journal-title":"Nat. Synth."},{"issue":"44","key":"2026080511144821900_cit48","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202510588","article-title":"Tunable Copolymerization\nof Oxetane and Anhydrides via a Nonsymmetric Three-Center Four-Electron\nIodine Activation Mode","volume":"64","author":"Hong","year":"2025","journal-title":"Angew. Chem., Int. Ed."},{"issue":"48","key":"2026080511144821900_cit49","doi-asserted-by":"publisher","first-page":"6618","DOI":"10.1002\/anie.200460442","article-title":"Discrete Metal-Based\nCatalysts for the Copolymerization\nof CO2 and Epoxides: Discovery, Reactivity, Optimization,\nand Mechanism","volume":"43","author":"Coates","year":"2004","journal-title":"Angew. Chem., Int. Ed."},{"issue":"5","key":"2026080511144821900_cit50","doi-asserted-by":"publisher","first-page":"1759","DOI":"10.1021\/acs.macromol.2c02483","article-title":"Current\nChallenges and Perspectives in CO2-Based Polymers","volume":"56","author":"Liu","year":"2023","journal-title":"Macromolecules"},{"issue":"2","key":"2026080511144821900_cit51","doi-asserted-by":"publisher","first-page":"111","DOI":"10.1016\/j.gce.2021.11.005","article-title":"Environmentally\nBenign Metal Catalyst for the Ring-Opening\nCopolymerization of Epoxide and CO2: State-of-the-Art,\nOpportunities, and Challenges","volume":"3","author":"Cao","year":"2022","journal-title":"Green Chem. Eng."},{"issue":"19","key":"2026080511144821900_cit52","doi-asserted-by":"publisher","first-page":"6519","DOI":"10.1016\/j.polymer.2004.07.044","article-title":"Copolymerization of Carbon Dioxide\nand Propylene Oxide with Highly Effective Zinc Hexacyanocobaltate(III)-Based\nCoordination Catalyst","volume":"45","author":"Chen","year":"2004","journal-title":"Polymer"},{"issue":"24","key":"2026080511144821900_cit53","doi-asserted-by":"publisher","first-page":"5494","DOI":"10.1016\/j.polymer.2011.09.040","article-title":"Selective Copolymerization of Carbon\nDioxide with Propylene Oxide Catalyzed by a Nanolamellar Double Metal\nCyanide Complex Catalyst at Low Polymerization Temperatures","volume":"52","author":"Zhang","year":"2011","journal-title":"Polymer"},{"key":"2026080511144821900_cit54","doi-asserted-by":"publisher","first-page":"192","DOI":"10.1080\/15583720701834240","article-title":"Poly(Propylene\nCarbonate), Old Copolymers of Propylene Oxide and Carbon Dioxide with\nNew Interests: Catalysis and Material Properties","volume":"48","author":"Luinstra","year":"2008","journal-title":"Polym. Rev."},{"issue":"1","key":"2026080511144821900_cit55","doi-asserted-by":"publisher","first-page":"141","DOI":"10.1039\/C0CC02207A","article-title":"Catalysts for CO2\/Epoxide\nCopolymerisation","volume":"47","author":"Kember","year":"2011","journal-title":"Chem. Commun."},{"issue":"1","key":"2026080511144821900_cit56","doi-asserted-by":"publisher","first-page":"150","DOI":"10.1021\/acs.macromol.3c02222","article-title":"Aggregate\nCatalysts: Regulating Multimetal Cooperativity for CO2\/Epoxide\nCopolymerization","volume":"57","author":"Yang","year":"2024","journal-title":"Macromolecules"},{"issue":"21","key":"2026080511144821900_cit57","doi-asserted-by":"publisher","first-page":"2599","DOI":"10.1002\/cjoc.202400398","article-title":"Polymeric Catalyst\nwith Discrete Distributed Active Centers for Regulating Backbone Structure\nof Poly(propylene carbonate)","volume":"42","author":"Zhou","year":"2024","journal-title":"Chin. J. Chem."},{"issue":"9","key":"2026080511144821900_cit58","doi-asserted-by":"publisher","first-page":"8669","DOI":"10.1021\/acscatal.9b02741","article-title":"Homogeneous Metallic\nOligomer Catalyst with Multisite Intramolecular Cooperativity for\nthe Synthesis of CO2-Based Polymers","volume":"9","author":"Cao","year":"2019","journal-title":"ACS Catal."},{"issue":"22","key":"2026080511144821900_cit59","doi-asserted-by":"publisher","first-page":"15116","DOI":"10.1021\/acscatal.3c04274","article-title":"Dynamic Foldamer Catalyst\nEnables Efficient Copolymerization of CO2 and Epoxides","volume":"13","author":"Zhou","year":"2023","journal-title":"ACS Catal."},{"issue":"10","key":"2026080511144821900_cit60","doi-asserted-by":"publisher","DOI":"10.1002\/cssc.202402546","article-title":"Pressure-Sensitive\nAdhesives Based on CO2-Based Polymer: Structure-Regulated\nViscoelasticity","volume":"18","author":"Zhou","year":"2025","journal-title":"ChemSusChem"},{"issue":"12","key":"2026080511144821900_cit61","doi-asserted-by":"publisher","first-page":"5702","DOI":"10.1021\/acs.macromol.4c00887","article-title":"Rigid-Flexible Binuclear\nCatalysts:\nBoosting Activity for Copolymerization of CO2 and Propylene\nOxide","volume":"57","author":"Fan","year":"2024","journal-title":"Macromolecules"},{"issue":"20","key":"2026080511144821900_cit62","doi-asserted-by":"publisher","first-page":"13042","DOI":"10.1021\/acscatal.2c03583","article-title":"Synthesis\nof Trimethylene Carbonates and Polycarbonates from Oxetanes and CO2 Using Bifunctional Aluminum Porphyrin Catalysts","volume":"12","author":"Maeda","year":"2022","journal-title":"ACS Catal."},{"issue":"8","key":"2026080511144821900_cit63","doi-asserted-by":"publisher","first-page":"3730","DOI":"10.1021\/acs.inorgchem.5b02295","article-title":"Crystallographic\nand Spectroscopic Studies of a Host\u2013Guest Complex Consisting\nof a Novel Zinc Trisporphyrinate and a Chiral Monoamine","volume":"55","author":"Han","year":"2016","journal-title":"Inorg. Chem."}],"container-title":["Journal of the American\nChemical Society"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/jacs.6c11991","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/jacsat\/article-pdf\/148\/30\/32881\/66196321\/jacs.6c11991.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/pubs.acs.org\/jacsat\/article-pdf\/148\/30\/32881\/66196321\/jacs.6c11991.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,5]],"date-time":"2026-08-05T15:23:13Z","timestamp":1785943393000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/jacsat\/article\/148\/30\/32881\/5229275\/Extremozymes-Inspired-Catalyst-for-Epoxide-Based"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7,23]]},"references-count":63,"journal-issue":{"issue":"30","published-online":{"date-parts":[[2026,7,23]]},"published-print":{"date-parts":[[2026,8,5]]}},"URL":"https:\/\/doi.org\/10.1021\/jacs.6c11991","relation":{},"ISSN":["0002-7863","1520-5126"],"issn-type":[{"value":"0002-7863","type":"print"},{"value":"1520-5126","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,7,23]]}}}