{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T15:56:37Z","timestamp":1792598197646,"version":"4.5.0"},"reference-count":67,"publisher":"American Chemical Society (ACS)","issue":"41","license":[{"start":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T00:00:00Z","timestamp":1787875200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T00:00:00Z","timestamp":1787875200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T00:00:00Z","timestamp":1787875200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/501100012226","name":"Fundamental Research Funds for the Central Universities","doi-asserted-by":"publisher","award":["5X010202131"],"award-info":[{"award-number":["5X010202131"]}],"id":[{"id":"10.13039\/501100012226","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012226","name":"Fundamental Research Funds for the Central Universities","doi-asserted-by":"publisher","award":["AYG2024QNA40"],"award-info":[{"award-number":["AYG2024QNA40"]}],"id":[{"id":"10.13039\/501100012226","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["22301178"],"award-info":[{"award-number":["22301178"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["22301180"],"award-info":[{"award-number":["22301180"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["22577072"],"award-info":[{"award-number":["22577072"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Basic research project of Shanghai Sixth People's Hospital","award":["ynqn202310"],"award-info":[{"award-number":["ynqn202310"]}]},{"name":"Open Grant from the Pingyuan Laboratory","award":["2023PY-OP-0102"],"award-info":[{"award-number":["2023PY-OP-0102"]}]},{"name":"Open Fund from the State Key Laboratory of Antiviral Drugs","award":["SKLAD-2024-0103"],"award-info":[{"award-number":["SKLAD-2024-0103"]}]},{"name":"National Key Research & Development Program of China","award":["2023YFA1508800"],"award-info":[{"award-number":["2023YFA1508800"]}]},{"name":"Jiangsu Province Natural Science Funds for Distinguished Young Scholar","award":["BK20240032"],"award-info":[{"award-number":["BK20240032"]}]},{"name":"LUI Che Woo Talent Development Fund","award":["LCW-ZIAS-2026B06"],"award-info":[{"award-number":["LCW-ZIAS-2026B06"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,10,21]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Metalloids bridge the properties of metals and nonmetals, creating unique opportunities in drug discovery. However, the potential of silicon- and germanium-containing scaffolds in organic synthesis and medicinal chemistry remain underexplored, largely owing to the lack of general stereocontrolled synthetic methods, particularly for value-added chiral \u03b1-silylamines and \u03b1-germylamines. Here, we report a robust nickel-catalyzed enantioselective decarboxylative cross-coupling of amino acid or peptide-derived redox-active esters with silylzinc and germylzinc reagents. The method exhibits a broad substrate scope and delivers excellent performance under mild conditions. Its efficacy is further demonstrated through the late-stage diversification of complex bioactive peptides, and both enantiomers can be accessed with high stereochemical fidelity. Mechanistic investigations delineate the origin of stereocontrol, while preliminary biological evaluations show promising activities, with Ge substitution in several cases surpassing Si and certain clinically marketed boron-containing drugs. Collectively, this work establishes an efficient and enantioselective route to chiral \u03b1-silylamines and \u03b1-germylamines, underscoring their potential to expand peptide chemical space and to enable the development of peptide-based therapeutics and diagnostics.<\/jats:p>","DOI":"10.1021\/jacs.6c12391","type":"journal-article","created":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T05:34:23Z","timestamp":1788327263000},"page":"44505-44519","source":"Crossref","is-referenced-by-count":2,"title":["Enantioselective Decarboxylative\nSynthesis of Chiral\n\u03b1-Silylamines and \u03b1-Germylamines"],"prefix":"10.1021","volume":"148","author":[{"given":"Qiang","family":"Tao","sequence":"first","affiliation":[{"name":"Shanghai Jiao Tong University , , ,","place":["Shanghai, P. R. China, 200240"]},{"name":"Nanjing Normal University , , ,","place":["Nanjing, P. R. China, 210023"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yujuan","family":"Wang","sequence":"additional","affiliation":[{"name":"Shanghai Jiao Tong University , , ,","place":["Shanghai, P. R. China, 200240"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ka","family":"Lu","sequence":"additional","affiliation":[{"name":"Shanghai Jiao Tong University , , ,","place":["Shanghai, P. R. China, 200240"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shiming","family":"Li","sequence":"additional","affiliation":[{"name":"Shanghai Jiao Tong University , , ,","place":["Shanghai, P. R. China, 200240"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meng","family":"Qiao","sequence":"additional","affiliation":[{"name":"Nanjing Normal University , , ,","place":["Nanjing, P. R. China, 210023"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yaoyong","family":"Zeng","sequence":"additional","affiliation":[{"name":"Shanghai Jiao Tong University , , ,","place":["Shanghai, P. R. China, 200240"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanyan","family":"Xu","sequence":"additional","affiliation":[{"name":"Shanghai Jiao Tong University , , ,","place":["Shanghai, P. R. China, 200240"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yang","family":"Han","sequence":"additional","affiliation":[{"name":"Shanghai Jiao Tong University , , ,","place":["Shanghai, P. R. China, 200240"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2699-3448","authenticated-orcid":true,"given":"Xing","family":"Zhang","sequence":"additional","affiliation":[{"name":"Nanjing Normal University , , ,","place":["Nanjing, P. R. China, 210023"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3350-8498","authenticated-orcid":true,"given":"Lingjun","family":"Zheng","sequence":"additional","affiliation":[{"name":"Shanghai Jiao Tong University , , ,","place":["Shanghai, P. R. China, 200240"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0612-5712","authenticated-orcid":true,"given":"Bo","family":"Yang","sequence":"additional","affiliation":[{"name":"Shanghai Jiao Tong University , , ,","place":["Shanghai, P. R. China, 200240"]},{"name":"Henan Normal University , , , ,","place":["Xinxiang, Henan, P. R. China, 453007"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3012-789X","authenticated-orcid":true,"given":"Feng","family":"Zhu","sequence":"additional","affiliation":[{"name":"Shanghai Jiao Tong University , , ,","place":["Shanghai, P. R. China, 200240"]},{"name":"Henan Normal University , , , ,","place":["Xinxiang, Henan, P. R. China, 453007"]},{"name":"Nankai University , , ,","place":["Tianjin, P. R. China, 300071"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2026,8,28]]},"reference":[{"issue":"3","key":"2026102111072825200_cit1","first-page":"145","article-title":"Metalloid\ncompounds as drugs","volume":"8","author":"Sekhon","year":"2013","journal-title":"Res. Pharm. Sci."},{"issue":"5","key":"2026102111072825200_cit2","doi-asserted-by":"publisher","first-page":"452","DOI":"10.1016\/j.tplants.2020.11.003","article-title":"Emerging\nTrends in Metalloid-Dependent\nSignaling in Plants","volume":"26","author":"Sharma","year":"2021","journal-title":"Trends Plant Sci."},{"issue":"5","key":"2026102111072825200_cit3","doi-asserted-by":"publisher","first-page":"2441","DOI":"10.1021\/acs.chemrev.3c00663","article-title":"The Rise of Boron-Containing\nCompounds: Advancements in Synthesis, Medicinal Chemistry, and Emerging\nPharmacology","volume":"124","author":"Grams","year":"2024","journal-title":"Chem. Rev."},{"issue":"11","key":"2026102111072825200_cit4","first-page":"2615","article-title":"Proteasome\ninhibitors: a novel class of potent and\neffective antitumor agents","volume":"59","author":"Adams","year":"1999","journal-title":"Cancer Res."},{"issue":"9","key":"2026102111072825200_cit5","doi-asserted-by":"publisher","first-page":"3779","DOI":"10.1021\/acs.jmedchem.7b00718","article-title":"Quest for Novel\nChemical Entities through Incorporation\nof Silicon in Drug Scaffolds","volume":"61","author":"Ramesh","year":"2018","journal-title":"J. Med. Chem."},{"issue":"2","key":"2026102111072825200_cit6","doi-asserted-by":"publisher","first-page":"388","DOI":"10.1021\/jm3010114","article-title":"Organosilicon Molecules\nwith Medicinal Applications","volume":"56","author":"Franz","year":"2013","journal-title":"J. Med. Chem."},{"issue":"5","key":"2026102111072825200_cit7","doi-asserted-by":"publisher","first-page":"485","DOI":"10.4155\/fmc-2016-0193","article-title":"Progress in\nthe Medicinal Chemistry of Silicon: C\/Si\nExchange and Beyond","volume":"9","author":"Fujii","year":"2017","journal-title":"Future Med. Chem."},{"issue":"1","key":"2026102111072825200_cit8","doi-asserted-by":"publisher","first-page":"160","DOI":"10.1021\/jm3013757","article-title":"Increased\nHydrophobicity and Estrogenic Activity of Simple Phenols with Silicon\nand Germanium-Containing Substituents","volume":"56","author":"Fujii","year":"2013","journal-title":"J. Med.\nChem."},{"issue":"2","key":"2026102111072825200_cit9","doi-asserted-by":"publisher","first-page":"102713","DOI":"10.1016\/j.chempr.2025.102713","article-title":"Stereoselective C(sp3)-Si\/Ge\nbond formation via nickel-catalyzed decarboxylative couplings","volume":"12","author":"Wang","year":"2026","journal-title":"Chem"},{"issue":"5","key":"2026102111072825200_cit10","doi-asserted-by":"publisher","first-page":"1375","DOI":"10.1021\/cr00037a011","article-title":"Uses of Silicon-Containing\nCompounds in the Synthesis\nof Natural Products","volume":"95","author":"Langkopf","year":"1995","journal-title":"Chem. Rev."},{"issue":"6","key":"2026102111072825200_cit11","doi-asserted-by":"publisher","first-page":"2063","DOI":"10.1021\/cr941074u","article-title":"Stereochemical\nControl in Organic\nSynthesis Using Silicon-Containing Compounds","volume":"97","author":"Fleming","year":"1997","journal-title":"Chem. Rev."},{"issue":"1","key":"2026102111072825200_cit12","doi-asserted-by":"publisher","first-page":"631","DOI":"10.1021\/acscatal.6b02374","article-title":"Recent Advances\nin Transition-Metal-Catalyzed\nSynthetic Transformations of Organosilicon Reagents","volume":"7","author":"Komiyama","year":"2017","journal-title":"ACS Catal."},{"issue":"2","key":"2026102111072825200_cit13","doi-asserted-by":"publisher","first-page":"457","DOI":"10.1021\/ar300200h","article-title":"Efficient\nRoutes to Carbon\u2013Silicon\nBond Formation for the Synthesis of Silicon-Containing Peptides and\nAzasilaheterocycles","volume":"46","author":"Min","year":"2013","journal-title":"Acc. Chem. Res."},{"issue":"17","key":"2026102111072825200_cit14","doi-asserted-by":"publisher","first-page":"18265","DOI":"10.1021\/jacs.6c03153","article-title":"Bringing Silicon\nto Drugs: Modular Construction of Sila-Pharmacophores for the Development\nof Target Protein Degraders","volume":"148","author":"Wu","year":"2026","journal-title":"J. Am. Chem. Soc."},{"issue":"17","key":"2026102111072825200_cit15","doi-asserted-by":"publisher","first-page":"8546","DOI":"10.1039\/D4CS00417E","article-title":"Organocatalytic\nenantioselective construction of Si-stereocenters: recent advances\nand perspectives","volume":"53","author":"Ye","year":"2024","journal-title":"Chem. Soc. Rev."},{"issue":"8","key":"2026102111072825200_cit16","doi-asserted-by":"publisher","first-page":"2529","DOI":"10.1021\/jm1013693","article-title":"Synopsis\nof Some Recent Tactical Application of Bioisosteres in Drug Design","volume":"54","author":"Meanwell","year":"2011","journal-title":"J. Med. Chem."},{"issue":"19","key":"2026102111072825200_cit17","doi-asserted-by":"publisher","first-page":"11654","DOI":"10.1021\/acs.chemrev.6b00122","article-title":"Silicon-Containing\nAmino Acids: Synthetic Aspects, Conformational Studies, and Applications\nto Bioactive Peptides","volume":"116","author":"Re\u0301mond","year":"2016","journal-title":"Chem. Rev."},{"issue":"24","key":"2026102111072825200_cit18","doi-asserted-by":"publisher","first-page":"8358","DOI":"10.1002\/chem.201600445","article-title":"Incorporation\nof \u03b2-Silicon-\u03b23-Amino Acids\nin the Antimicrobial Peptide Alamethicin Provides a 20-Fold Increase\nin Membrane Permeabilization","volume":"22","author":"Madsen","year":"2016","journal-title":"Chem.\u2013Eur.\nJ."},{"issue":"2","key":"2026102111072825200_cit19","doi-asserted-by":"publisher","first-page":"311","DOI":"10.1002\/ejoc.200500508","article-title":"Silanediol Protease\nInhibitors: From Conception to\nValidation","volume":"2006","author":"Sieburth","year":"2006","journal-title":"Eur. J. Org. Chem."},{"issue":"8","key":"2026102111072825200_cit20","doi-asserted-by":"publisher","first-page":"1661","DOI":"10.1021\/cs300290j","article-title":"Enantiocontrol with a Hydrogen-bond\nDirecting Pyrrolidinylsilanol Catalyst","volume":"2","author":"Min","year":"2012","journal-title":"ACS\nCatal."},{"issue":"15","key":"2026102111072825200_cit21","doi-asserted-by":"publisher","first-page":"3528","DOI":"10.1021\/ol101379t","article-title":"Stereocontrolled Synthesis of 2-Substituted-1,3-Azasilaheterocycles","volume":"12","author":"Herna\u0301ndez","year":"2010","journal-title":"Org. Lett."},{"issue":"10","key":"2026102111072825200_cit22","doi-asserted-by":"publisher","first-page":"1497","DOI":"10.1055\/a-2006-9754","article-title":"Advances in Enantioconvergent Transition-Metal-Catalyzed\nCross-Coupling Reactions of Racemic \u03b1-Silyl and \u03b1-Boryl\nReagents","volume":"55","author":"Kranidiotis-Hisatomi","year":"2023","journal-title":"Synthesis"},{"issue":"19","key":"2026102111072825200_cit23","doi-asserted-by":"publisher","DOI":"10.1002\/chem.202203475","article-title":"Chiral Silanols: Strategies and Tactics for Their Synthesis","volume":"29","author":"Gao","year":"2023","journal-title":"Chem.\u2013Eur. J."},{"issue":"4","key":"2026102111072825200_cit24","doi-asserted-by":"publisher","first-page":"1157","DOI":"10.31635\/ccschem.024.202404335","article-title":"Cu-Catalyzed Asymmetric\nHydrogermylation Towards C- and Ge-Stereogenic Germanes","volume":"7","author":"Lin","year":"2025","journal-title":"CCS Chem."},{"issue":"3","key":"2026102111072825200_cit25","doi-asserted-by":"publisher","first-page":"375","DOI":"10.1021\/acs.accounts.4c00667","article-title":"Catalytic\nAsymmetric Dehydrogenative Si\u2013H\/X\u2013H\nCoupling toward Si-Stereogenic Silanes","volume":"58","author":"Ge","year":"2025","journal-title":"Acc.\nChem. Res."},{"issue":"23","key":"2026102111072825200_cit26","doi-asserted-by":"publisher","first-page":"14592","DOI":"10.1021\/acscatal.2c04571","article-title":"Cu-Catalyzed Enantioselective Hydrogermylation:\nAsymmetric Synthesis of Unnatural \u03b2-Germyl \u03b1-Amino Acids","volume":"12","author":"Lin","year":"2022","journal-title":"ACS Catal."},{"issue":"3","key":"2026102111072825200_cit27","doi-asserted-by":"publisher","first-page":"1777","DOI":"10.1039\/C0CS00037J","article-title":"The recent\nsynthesis and application\nof silicon-stereogenic silanes: A renewed and significant challenge\nin asymmetric synthesis","volume":"40","author":"Xu","year":"2011","journal-title":"Chem. Soc. Rev."},{"issue":"36","key":"2026102111072825200_cit28","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202205382","article-title":"Silicon-Stereogenic\nMonohydrosilane: Synthesis and Applications","volume":"61","author":"Wu","year":"2022","journal-title":"Angew. Chem., Int. Ed."},{"issue":"12","key":"2026102111072825200_cit29","doi-asserted-by":"publisher","first-page":"3461","DOI":"10.1016\/j.chempr.2023.09.024","article-title":"Catalytic asymmetric\nsynthesis of silicon-stereogenic organosilanes","volume":"9","author":"Wu","year":"2023","journal-title":"Chem"},{"issue":"1","key":"2026102111072825200_cit30","doi-asserted-by":"publisher","first-page":"16","DOI":"10.1021\/acscatal.8b04230","article-title":"C(sp3)\u2013Si Cross-Coupling","volume":"9","author":"Ba\u0308hr","year":"2019","journal-title":"ACS Catal."},{"issue":"19","key":"2026102111072825200_cit31","doi-asserted-by":"publisher","first-page":"6440","DOI":"10.1002\/anie.201901860","article-title":"Mechanistic Dichotomy of Magnesium-\nand Zinc-Based Germanium Nucleophiles in the C(sp3)\u2013Ge\nCross-Coupling with Alkyl Electrophiles","volume":"58","author":"Xue","year":"2019","journal-title":"Angew.\nChem., Int. Ed."},{"issue":"22","key":"2026102111072825200_cit32","doi-asserted-by":"publisher","first-page":"6558","DOI":"10.1039\/D4QO01637H","article-title":"Transition-metal-catalyzed C\u2013Ge coupling reactions","volume":"11","author":"Ke","year":"2024","journal-title":"Org. Chem. Front."},{"issue":"8","key":"2026102111072825200_cit33","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202314709","article-title":"Recent Developments\nwith Organogermanes: their Preparation and Application in Synthesis\nand Catalysis","volume":"63","author":"Rogova","year":"2024","journal-title":"Angew. Chem., Int. Ed."},{"issue":"7","key":"2026102111072825200_cit34","doi-asserted-by":"publisher","first-page":"6198","DOI":"10.1021\/acscatal.6c00700","article-title":"Asymmetric\nTransition-Metal-Catalyzed Hydrofunctionalization\nof Alkenylmetalloids (B, Si, and Ge)","volume":"16","author":"Bro\u0308samlen","year":"2026","journal-title":"ACS Catal."},{"issue":"11","key":"2026102111072825200_cit35","doi-asserted-by":"publisher","first-page":"2715","DOI":"10.1021\/acs.accounts.0c00527","article-title":"Organogermanes\nas Orthogonal Coupling Partners in Synthesis\nand Catalysis","volume":"53","author":"Fricke","year":"2020","journal-title":"Acc. Chem. Res."},{"issue":"2","key":"2026102111072825200_cit36","doi-asserted-by":"publisher","first-page":"452","DOI":"10.1021\/acs.accounts.0c00740","article-title":"The Discovery\nof Multifunctional Chiral P Ligands for\nthe Catalytic Construction of Quaternary Carbon\/Silicon and Multiple\nStereogenic Centers","volume":"54","author":"Ye","year":"2021","journal-title":"Acc. Chem. Res."},{"issue":"1","key":"2026102111072825200_cit37","doi-asserted-by":"publisher","first-page":"12","DOI":"10.1038\/s41929-023-01052-w","article-title":"Enantioconvergent\nand regioselective reductive coupling of propargylic esters with chlorogermanes\nby nickel catalysis","volume":"7","author":"Han","year":"2024","journal-title":"Nat. Catal."},{"issue":"7987","key":"2026102111072825200_cit38","doi-asserted-by":"publisher","first-page":"538","DOI":"10.1038\/s41586-023-06646-9","article-title":"Arenium-ion-catalysed\nhalodealkylation\nof fully alkylated silanes","volume":"623","author":"He","year":"2023","journal-title":"Nature"},{"key":"2026102111072825200_cit39","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1016\/j.ccr.2016.09.011","article-title":"Catalytic\nsynthesis of chiral organoheteroatom compounds\nof silicon, phosphorus, and sulfur via asymmetric transition metal-catalyzed\nC\u2013H functionalization","volume":"330","author":"Cui","year":"2017","journal-title":"Coord. Chem. Rev."},{"issue":"23","key":"2026102111072825200_cit40","doi-asserted-by":"publisher","first-page":"8937","DOI":"10.1002\/anie.202002289","article-title":"Asymmetric\nSynthesis and Application of Chiral Spirosilabiindanes","volume":"59","author":"Chang","year":"2020","journal-title":"Angew. Chem., Int. Ed."},{"issue":"49","key":"2026102111072825200_cit41","doi-asserted-by":"publisher","first-page":"25723","DOI":"10.1002\/anie.202111025","article-title":"Nickel(0)-Catalyzed Asymmetric Ring\nExpansion Toward Enantioenriched Silicon-Stereogenic Benzosiloles","volume":"60","author":"Zhang","year":"2021","journal-title":"Angew. Chem., Int. Ed."},{"issue":"36","key":"2026102111072825200_cit42","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202405520","article-title":"Divergent Synthesis of Enantioenriched Silicon-Stereogenic Benzyl-Vinyl-\nand Borylsilanes via Asymmetric Aryl to Alkyl 1,5-Palladium Migration","volume":"63","author":"Shi","year":"2024","journal-title":"Angew. Chem., Int. Ed."},{"issue":"1","key":"2026102111072825200_cit43","doi-asserted-by":"publisher","first-page":"7093","DOI":"10.1038\/s41467-022-34901-6","article-title":"Regioselective Ni-Catalyzed reductive alkylsilylation of acrylonitrile\nwith unactivated alkyl bromides and chlorosilanes","volume":"13","author":"Sun","year":"2022","journal-title":"Nat. Commun."},{"issue":"33","key":"2026102111072825200_cit44","doi-asserted-by":"publisher","first-page":"23092","DOI":"10.1021\/jacs.4c04390","article-title":"Lewis Base-Catalyzed\nDynamic Kinetic Asymmetric Transformation\nof Racemic Chlorosilanes en Route to Si-Stereogenic Silylethers","volume":"146","author":"Hu","year":"2024","journal-title":"J. Am. Chem. Soc."},{"issue":"48","key":"2026102111072825200_cit45","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202212889","article-title":"Enantioselective Synthesis\nof Spirosilabicyclohexenes by Asymmetric Dual Ring Expansion of Spirosilabicyclobutane\nwith Alkynes","volume":"61","author":"Chen","year":"2022","journal-title":"Angew. Chem., Int. 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