{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T18:49:00Z","timestamp":1792003740169,"version":"4.4.0"},"reference-count":69,"publisher":"American Chemical Society (ACS)","issue":"40","license":[{"start":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T00:00:00Z","timestamp":1790899200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004189","name":"Max-Planck-Gesellschaft","doi-asserted-by":"publisher","award":["NA"],"award-info":[{"award-number":["NA"]}],"id":[{"id":"10.13039\/501100004189","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,10,14]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Inorganic polyphosphate (polyP) is a ubiquitous phosphate biopolymer involved in diverse cellular processes. Despite its significance, selective detection of polyP remains challenging because of its simple and highly charged structure. Here, we report a far-red fluorogenic turn-on chemosensor for selective polyP detection and imaging, SiX-DPA-Zn. It integrates a silicon-xanthene fluorophore with a Zn(II)-coordinated 2,2\u2019-dipicolylamine recognition unit. Replacing the bridging oxygen in the xanthene scaffold with silicon shifts fluorescence into the far-red region and confers up to 100-fold selectivity for inorganic polyP over other phosphate-containing biomolecules, including nucleic acids and nucleoside di(tri)phosphates. SiX-DPA-Zn enables quantitative detection of polyP at micromolar concentrations in microplate assays and stains a broad range of polyP species, starting from tripolyphosphate, in polyacrylamide gels. In HEK293 cells expressing Escherichia coli polyphosphate kinase 1, the probe visualizes intracellular polyP and enables quantitative analysis of its distribution relative to nuclear proteins\u2500fibrillarin and nucleolin. Stimulated emission depletion (STED) microscopy further resolves subdiffraction-sized polyP granules within nuclear polyP aggregates. Together, these results establish SiX-DPA-Zn as a versatile chemical tool for quantitative polyP detection across biochemical assays and advanced fluorescence imaging.<\/jats:p>","DOI":"10.1021\/jacs.6c14037","type":"journal-article","created":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T04:01:45Z","timestamp":1791000105000},"page":"43649-43660","source":"Crossref","is-referenced-by-count":0,"title":["Far-Red Turn-On Fluorogenic\nProbe for Versatile Detection\nof Inorganic Polyphosphates"],"prefix":"10.1021","volume":"148","author":[{"given":"Kenji","family":"Torii","sequence":"first","affiliation":[{"name":"Max Planck Institute for Multidisciplinary Sciences , , Am Fassberg 11 , ,","place":["Go\u0308ttingen, Germany, 37077"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4898-1496","authenticated-orcid":true,"given":"Ru\u0305ta","family":"Gerasimaite\u0307","sequence":"additional","affiliation":[{"name":"Max Planck Institute for Multidisciplinary Sciences , , Am Fassberg 11 , ,","place":["Go\u0308ttingen, Germany, 37077"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7176-1793","authenticated-orcid":true,"given":"Graz\u030cvydas","family":"Lukinavic\u030cius","sequence":"additional","affiliation":[{"name":"Max Planck Institute for Multidisciplinary Sciences , , Am Fassberg 11 , ,","place":["Go\u0308ttingen, Germany, 37077"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2026,10,2]]},"reference":[{"issue":"3","key":"2026101414092839100_cit1","doi-asserted-by":"publisher","first-page":"491","DOI":"10.1128\/jb.177.3.491-496.1995","article-title":"Inorganic\nPolyphosphate: Toward Making a Forgotten Polymer Unforgettable","volume":"177","author":"Kornberg","year":"1995","journal-title":"J. Bacteriol."},{"key":"2026101414092839100_cit2","doi-asserted-by":"publisher","first-page":"89","DOI":"10.1146\/annurev.biochem.68.1.89","article-title":"Inorganic\nPolyphosphate: A Molecule\nof Many Functions","volume":"68","author":"Kornberg","year":"1999","journal-title":"Annu. Rev. Biochem."},{"issue":"46","key":"2026101414092839100_cit3","doi-asserted-by":"publisher","first-page":"16085","DOI":"10.1073\/pnas.0406909101","article-title":"Inorganic Polyphosphate\nin the Origin and Survival\nof Species","volume":"101","author":"Brown","year":"2004","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"2026101414092839100_cit4","doi-asserted-by":"publisher","first-page":"103303","DOI":"10.1016\/j.copbio.2025.103303","article-title":"Polyphosphate:\nA Cellular Swiss Army Knife","volume":"93","author":"Rai","year":"2025","journal-title":"Curr. Opin. Biotechnol."},{"issue":"5","key":"2026101414092839100_cit5","doi-asserted-by":"publisher","first-page":"367","DOI":"10.1016\/0006-291X(63)90124-4","article-title":"Synthesis of Polyphosphate\nby Rat Liver Mitochondria","volume":"11","author":"Lynn","year":"1963","journal-title":"Biochem. Biophys.\nRes. Commun."},{"issue":"9","key":"2026101414092839100_cit6","doi-asserted-by":"publisher","first-page":"1089","DOI":"10.1016\/0300-9084(89)90115-6","article-title":"Polyphosphate\nas a Source of Phosphoryl Group in Protein Modification in the Archaebacterium\nSulfolobus Acidocaldarius","volume":"71","author":"Skorko","year":"1989","journal-title":"Biochimie"},{"issue":"8","key":"2026101414092839100_cit7","doi-asserted-by":"publisher","first-page":"1515","DOI":"10.1042\/BCJ20200042","article-title":"Inorganic Polyphosphate Is Produced\nand Hydrolyzed in F0F1-ATP Synthase of Mammalian Mitochondria","volume":"477","author":"Baev","year":"2020","journal-title":"Biochem. J."},{"issue":"5","key":"2026101414092839100_cit8","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0005634","article-title":"Control of Vertebrate\nSkeletal Mineralization by Polyphosphates","volume":"4","author":"Omelon","year":"2009","journal-title":"PLoS\nOne"},{"issue":"5","key":"2026101414092839100_cit9","doi-asserted-by":"publisher","first-page":"463","DOI":"10.1111\/1567-1364.12049","article-title":"Adaptation of Saccharomyces Cerevisiae to Toxic Manganese\nConcentration Triggers Changes in Inorganic Polyphosphates","volume":"13","author":"Andreeva","year":"2013","journal-title":"FEMS Yeast Res."},{"issue":"3","key":"2026101414092839100_cit10","doi-asserted-by":"publisher","first-page":"1234","DOI":"10.1104\/pp.97.3.1234","article-title":"Polyphosphate Hydrolysis\nwithin Acidic Vacuoles in Response to Amine-Induced\nAlkaline Stress in the Halotolerant Alga Dunaliella Salina","volume":"97","author":"Pick","year":"1991","journal-title":"Plant Physiol."},{"issue":"5","key":"2026101414092839100_cit11","doi-asserted-by":"publisher","first-page":"689","DOI":"10.1016\/j.molcel.2014.01.012","article-title":"Polyphosphate\nIs a Primordial Chaperone","volume":"53","author":"Gray","year":"2014","journal-title":"Mol. Cell"},{"issue":"21","key":"2026101414092839100_cit12","doi-asserted-by":"publisher","first-page":"4195","DOI":"10.1016\/j.jmb.2018.08.016","article-title":"Polyphosphate\nStabilizes Protein Unfolding Intermediates as Soluble Amyloid-like\nOligomers","volume":"430","author":"Yoo","year":"2018","journal-title":"J. Mol. Biol."},{"issue":"14","key":"2026101414092839100_cit13","doi-asserted-by":"publisher","first-page":"168504","DOI":"10.1016\/j.jmb.2024.168504","article-title":"The Protein Scaffolding\nFunctions of Polyphosphate","volume":"436","author":"Guan","year":"2024","journal-title":"J. Mol. Biol."},{"issue":"4","key":"2026101414092839100_cit14","doi-asserted-by":"publisher","first-page":"108318","DOI":"10.1016\/j.celrep.2020.108318","article-title":"A Broad Response to Intracellular Long-Chain Polyphosphate\nin Human Cells","volume":"33","author":"Bondy-Chorney","year":"2020","journal-title":"Cell Rep."},{"key":"2026101414092839100_cit15","doi-asserted-by":"publisher","first-page":"171","DOI":"10.1016\/j.dnarep.2017.08.001","article-title":"Polyphosphate Is a\nKey Factor for Cell Survival after DNA Damage in Eukaryotic Cells","volume":"57","author":"Bru","year":"2017","journal-title":"DNA Repair"},{"issue":"4","key":"2026101414092839100_cit16","doi-asserted-by":"publisher","first-page":"903","DOI":"10.1073\/pnas.0507195103","article-title":"Polyphosphate Modulates Blood Coagulation\nand Fibrinolysis","volume":"103","author":"Smith","year":"2006","journal-title":"Proc. Natl. Acad. Sci. U.\nS. A."},{"issue":"6","key":"2026101414092839100_cit17","doi-asserted-by":"publisher","first-page":"1143","DOI":"10.1016\/j.cell.2009.11.001","article-title":"Platelet Polyphosphates Are Proinflammatory and Procoagulant\nMediators In Vivo","volume":"139","author":"Mu\u0308ller","year":"2009","journal-title":"Cell"},{"issue":"5","key":"2026101414092839100_cit18","doi-asserted-by":"publisher","first-page":"860","DOI":"10.1111\/jth.12899","article-title":"Inorganic Polyphosphate\nElicits Pro-inflammatory Responses through Activation of the Mammalian\nTarget of Rapamycin Complexes 1 and 2 in Vascular Endothelial Cells","volume":"13","author":"Hassanian","year":"2015","journal-title":"J. Thromb. Haemostasis"},{"issue":"10","key":"2026101414092839100_cit19","doi-asserted-by":"publisher","first-page":"1656","DOI":"10.1016\/j.neuron.2022.02.010","article-title":"Excessive Release of Inorganic Polyphosphate by ALS\/FTD\nAstrocytes Causes Non-Cell-Autonomous Toxicity to Motoneurons","volume":"110","author":"Arredondo","year":"2022","journal-title":"Neuron"},{"issue":"1","key":"2026101414092839100_cit20","doi-asserted-by":"publisher","first-page":"123","DOI":"10.1042\/BST20230257","article-title":"Inorganic\nPolyphosphate: From Basic Research to Diagnostic and Therapeutic Opportunities\nin ALS\/FTD","volume":"52","author":"Garce\u0301s","year":"2024","journal-title":"Biochem. Soc. Trans."},{"issue":"6","key":"2026101414092839100_cit21","doi-asserted-by":"publisher","first-page":"4167","DOI":"10.1021\/acs.analchem.9b05144","article-title":"Methods\nfor the Analysis of Polyphosphate\nin the Life Sciences","volume":"92","author":"Christ","year":"2020","journal-title":"Anal. Chem."},{"issue":"4","key":"2026101414092839100_cit22","doi-asserted-by":"publisher","DOI":"10.4081\/ejh.2013.e34","article-title":"New insights into the\nin situ microscopic visualization and quantification of inorganic\npolyphosphate stores by 4\u2019,6-diamidino-2-phenylindole (DAPI)-staining","volume":"57","author":"Gomes","year":"2013","journal-title":"Eur. J. Histochem."},{"issue":"5","key":"2026101414092839100_cit23","doi-asserted-by":"publisher","first-page":"859","DOI":"10.1007\/s10895-008-0315-4","article-title":"High Sensitivity, Quantitative Measurements\nof Polyphosphate Using a New DAPI-Based Approach","volume":"18","author":"Aschar-Sobbi","year":"2008","journal-title":"J. Fluoresc."},{"issue":"1","key":"2026101414092839100_cit24","doi-asserted-by":"publisher","first-page":"46","DOI":"10.1042\/BST20150231","article-title":"A Cautionary (Spectral)\nTail: Red-Shifted\nFluorescence by DAPI\u2013DAPI Interactions","volume":"44","author":"Omelon","year":"2016","journal-title":"Biochem. Soc. Trans."},{"issue":"9","key":"2026101414092839100_cit25","doi-asserted-by":"publisher","first-page":"1323","DOI":"10.1177\/38.9.1696951","article-title":"Interactions\nof Nucleic Acids with Fluorescent Dyes: Spectral Properties of Condensed\nComplexes","volume":"38","author":"Kapuscinski","year":"1990","journal-title":"J. Histochem. Cytochem."},{"issue":"3","key":"2026101414092839100_cit26","doi-asserted-by":"publisher","first-page":"377","DOI":"10.1042\/BJ20140237","article-title":"Inositol Phosphates Induce DAPI Fluorescence\nShift","volume":"460","author":"Kolozsvari","year":"2014","journal-title":"Biochem. J."},{"issue":"9","key":"2026101414092839100_cit27","doi-asserted-by":"publisher","first-page":"2101","DOI":"10.1021\/cb5000696","article-title":"In Situ Investigation\nof Mammalian Inorganic Polyphosphate Localization Using Novel Selective\nFluorescent Probes JC-D7 and JC-D8","volume":"9","author":"Angelova","year":"2014","journal-title":"ACS Chem.\nBiol."},{"issue":"6","key":"2026101414092839100_cit28","doi-asserted-by":"publisher","first-page":"1373","DOI":"10.1039\/D4OB01926A","article-title":"ESIPT Fluorescence Turn-on Sensors for Detection of\nShort Chain Inorganic Polyphosphate in Water","volume":"23","author":"Roy","year":"2025","journal-title":"Org. Biomol. Chem."},{"issue":"10","key":"2026101414092839100_cit29","doi-asserted-by":"publisher","first-page":"5692","DOI":"10.1128\/AEM.71.10.5692-5701.2005","article-title":"Direct Labeling\nof Polyphosphate at the Ultrastructural Level in Saccharomyces Cerevisiae\nby Using the Affinity of the Polyphosphate Binding Domain of Escherichia\nColi Exopolyphosphatase","volume":"71","author":"Saito","year":"2005","journal-title":"Appl. Environ. Microbiol."},{"issue":"7","key":"2026101414092839100_cit30","doi-asserted-by":"publisher","first-page":"110004","DOI":"10.1016\/j.celrep.2021.110004","article-title":"Polyphosphate Degradation by Nudt3-Zn2+ Mediates Oxidative Stress\nResponse","volume":"37","author":"Samper-Marti\u0301n","year":"2021","journal-title":"Cell Rep."},{"issue":"2","key":"2026101414092839100_cit31","doi-asserted-by":"publisher","first-page":"101363","DOI":"10.1016\/j.xpro.2022.101363","article-title":"Protocol to Quantify Polyphosphate\nin Human Cell Lines Using a Tagged PPBD Peptide","volume":"3","author":"Jime\u0301nez","year":"2022","journal-title":"STAR Protoc."},{"issue":"7","key":"2026101414092839100_cit32","doi-asserted-by":"publisher","first-page":"100814","DOI":"10.1016\/j.crmeth.2024.100814","article-title":"A Mammalian\nModel Reveals Inorganic Polyphosphate Channeling into the Nucleolus\nand Induction of a Hyper-Condensate State","volume":"4","author":"Borghi","year":"2024","journal-title":"Cell\nRep. Methods"},{"issue":"3\u20134","key":"2026101414092839100_cit33","doi-asserted-by":"publisher","first-page":"169","DOI":"10.1002\/ijch.202000087","article-title":"Fluorescent\nSensors of Phosphate Containing Biomolecules","volume":"61","author":"Nag","year":"2021","journal-title":"Isr. J. Chem."},{"key":"2026101414092839100_cit34","doi-asserted-by":"publisher","first-page":"30","DOI":"10.1007\/s41061-017-0120-0.","article-title":"Fluorescence\nSensing of Inorganic\nPhosphate and Pyrophosphate Using Small Molecular Sensors and Their\nApplications","volume":"375","author":"Wongkongkatep","year":"2017","journal-title":"Top Curr. Chem."},{"key":"2026101414092839100_cit35","doi-asserted-by":"publisher","first-page":"169","DOI":"10.1016\/j.dyepig.2014.04.009","article-title":"Zinc(II)-Based Fluorescent\nDyes: Luminescence Modulation by Phosphate Anion Binding","volume":"110","author":"Bencini","year":"2014","journal-title":"Dyes Pigm."},{"issue":"2","key":"2026101414092839100_cit36","doi-asserted-by":"publisher","first-page":"141","DOI":"10.1039\/B812374H","article-title":"Molecular Recognition,\nFluorescence\nSensing, and Biological Assay of Phosphate Anion Derivatives Using\nArtificial Zn(II)\u2013Dpa Complexes","author":"Sakamoto","year":"2009","journal-title":"Chem.\nCommun."},{"issue":"14","key":"2026101414092839100_cit37","doi-asserted-by":"publisher","first-page":"4928","DOI":"10.1039\/C2CS35087D","article-title":"Anion Recognition and Sensing with\nZn(II)\u2013Dipicolylamine Complexes","volume":"41","author":"Tien Ngo","year":"2012","journal-title":"Chem.\nSoc. Rev."},{"issue":"49","key":"2026101414092839100_cit38","doi-asserted-by":"publisher","first-page":"8683","DOI":"10.1016\/j.tetlet.2007.10.022","article-title":"Fluorescent\nSensing of Pyrophosphate\nand ATP in 100% Aqueous Solution Using a Fluorescein Derivative and\nMn2+","volume":"48","author":"Swamy","year":"2007","journal-title":"Tetrahedron Lett."},{"issue":"36","key":"2026101414092839100_cit39","doi-asserted-by":"publisher","first-page":"12095","DOI":"10.1021\/ja803262w","article-title":"Turn-on Fluorescence\nSensing of Nucleoside Polyphosphates Using a Xanthene-Based Zn(II)\nComplex Chemosensor","volume":"130","author":"Ojida","year":"2008","journal-title":"J. Am. Chem. Soc."},{"issue":"45","key":"2026101414092839100_cit40","doi-asserted-by":"publisher","first-page":"18779","DOI":"10.1021\/ja308754g","article-title":"Organelle-Localizable\nFluorescent Chemosensors for Site-Specific Multicolor Imaging of Nucleoside\nPolyphosphate Dynamics in Living Cells","volume":"134","author":"Kurishita","year":"2012","journal-title":"J. Am.\nChem. Soc."},{"issue":"38","key":"2026101414092839100_cit41","doi-asserted-by":"publisher","first-page":"6634","DOI":"10.1039\/C4TB01109K","article-title":"A Benzothiazole-Based Sensor for Pyrophosphate (PPi)\nand ATP: Mechanistic Insight for Anion-Induced ESIPT Turn-On","volume":"2","author":"Wang","year":"2014","journal-title":"J. Mater. Chem. B"},{"key":"2026101414092839100_cit42","doi-asserted-by":"publisher","first-page":"657","DOI":"10.1016\/j.saa.2018.06.094","article-title":"Dual-Functional Probe\nBased on Rhodamine for Sequential Cu2+ and ATP Detection in Vivo","volume":"204","author":"Jin","year":"2018","journal-title":"Spectrochim. Acta, Part A"},{"issue":"7","key":"2026101414092839100_cit43","doi-asserted-by":"publisher","first-page":"417","DOI":"10.3390\/chemosensors11070417","article-title":"Recent Advances\nin Design Strategies and Imaging Applications of\nFluorescent Probes for ATP","volume":"11","author":"Gu","year":"2023","journal-title":"Chemosensors"},{"issue":"1","key":"2026101414092839100_cit44","doi-asserted-by":"publisher","first-page":"471","DOI":"10.3390\/s23010471","article-title":"A Near InfraRed\nEmissive Chemosensor for Zn2+ and Phosphate Derivatives Based on a\nDi-(2-Picolyl)Amine-Styrylflavylium Push-Pull Fluorophore","volume":"23","author":"Gomes","year":"2023","journal-title":"Sensors"},{"issue":"11","key":"2026101414092839100_cit45","doi-asserted-by":"publisher","first-page":"7199","DOI":"10.1021\/acs.cgd.8b01409","article-title":"A Fluorescent Chemodosimeter\nfor Organelle-Specific Imaging of Nucleoside Polyphosphate Dynamics\nin Living Cells","volume":"18","author":"Singh","year":"2018","journal-title":"Cryst. Growth Des."},{"issue":"23","key":"2026101414092839100_cit46","doi-asserted-by":"publisher","first-page":"9603","DOI":"10.1021\/jo0509657","article-title":"Highly Effective Fluorescent and Colorimetric Sensors for Pyrophosphate\nover H2PO4- in 100% Aqueous Solution","volume":"70","author":"Jang","year":"2005","journal-title":"J. Org.\nChem."},{"issue":"46","key":"2026101414092839100_cit47","doi-asserted-by":"publisher","first-page":"7215","DOI":"10.1039\/b913809a","article-title":"Pyrophosphate Selective\nFluorescent Chemosensors Based on Coumarin\u2013DPA\u2013Cu(II)\nComplexes","author":"Kim","year":"2009","journal-title":"Chem. Commun."},{"issue":"6","key":"2026101414092839100_cit48","doi-asserted-by":"publisher","first-page":"1362","DOI":"10.1021\/ol200054w","article-title":"A Highly Selective\nPyrophosphate\nSensor Based on ESIPT Turn-On in Water","volume":"13","author":"Chen","year":"2011","journal-title":"Org.\nLett."},{"issue":"19","key":"2026101414092839100_cit49","doi-asserted-by":"publisher","first-page":"5294","DOI":"10.1021\/ol202159x","article-title":"Pyrophosphate-Selective\nFluorescent Chemosensor Based on 1,8-Naphthalimide\u2013DPA\u2013Zn(II)\nComplex and Its Application for Cell Imaging","volume":"13","author":"Zhang","year":"2011","journal-title":"Org. Lett."},{"issue":"52","key":"2026101414092839100_cit50","doi-asserted-by":"publisher","first-page":"4574","DOI":"10.1016\/j.tetlet.2018.11.031","article-title":"Quest for Novel Fluorogenic Xanthene\nDyes: Synthesis, Spectral Properties and Stability of 3-Imino-3H-Xanthen-6-Amine\n(Pyronin) and Its Silicon Analog","volume":"59","author":"Romieu","year":"2018","journal-title":"Tetrahedron\nLett."},{"issue":"8","key":"2026101414092839100_cit51","doi-asserted-by":"publisher","first-page":"3374","DOI":"10.1021\/jo500140y","article-title":"Near-Infrared Fluorescent 9-Phenylethynylpyronin\nAnalogues\nfor Bioimaging","volume":"79","author":"Pastierik","year":"2014","journal-title":"J. Org. Chem."},{"issue":"1","key":"2026101414092839100_cit52","doi-asserted-by":"publisher","first-page":"32","DOI":"10.1021\/acssensors.5b00022","article-title":"Reaction-Based Probes\nfor Imaging Mobile Zinc in Live Cells and Tissues","volume":"1","author":"Zastrow","year":"2016","journal-title":"ACS Sens."},{"issue":"1","key":"2026101414092839100_cit53","doi-asserted-by":"publisher","first-page":"143","DOI":"10.1073\/pnas.1310583110","article-title":"Reaction-Based\nFluorescent\nSensor for Investigating Mobile Zn2+ in Mitochondria of Healthy versus\nCancerous Prostate Cells","volume":"111","author":"Chyan","year":"2014","journal-title":"Proc. Natl. Acad.\nSci. U. S. A."},{"key":"2026101414092839100_cit54","doi-asserted-by":"publisher","first-page":"14249","DOI":"10.1021\/acs.est.4c04545","article-title":"Quantification\nof Polyphosphate in Environmental Planktonic Samples Using a Novel\nFluorescence Dye JC-D7","volume":"58","author":"Yang","year":"2024","journal-title":"Environ. Sci. Technol."},{"issue":"11","key":"2026101414092839100_cit55","doi-asserted-by":"publisher","first-page":"2104","DOI":"10.1007\/s10953-013-0099-2","article-title":"Stabilities of the\nDivalent Metal Ion Complexes of\na Short-Chain Polyphosphate Anion and Its Imino Derivative","volume":"42","author":"Maki","year":"2013","journal-title":"J. Solut. Chem."},{"issue":"20","key":"2026101414092839100_cit56","doi-asserted-by":"publisher","first-page":"14185","DOI":"10.1021\/acs.est.1c04782","article-title":"Molecular\nCoordination, Structure, and Stability of Metal-Polyphosphate Complexes\nResolved by Molecular Modeling and X-Ray Scattering: Structural Insights\non the Biological Fate of Polyphosphate","volume":"55","author":"Park","year":"2021","journal-title":"Environ.\nSci. Technol."},{"key":"2026101414092839100_cit57","doi-asserted-by":"publisher","first-page":"254","DOI":"10.1016\/S0167-4838(01)00193-5","article-title":"Mammalian Intestinal Alkaline Phosphatase Acts as Highly\nActive Exopolyphosphatase","volume":"2","author":"Lorenz","year":"2001","journal-title":"Biochim. Biophys.\nActa"},{"issue":"1","key":"2026101414092839100_cit58","doi-asserted-by":"publisher","first-page":"112","DOI":"10.1016\/0003-2697(91)90194-X","article-title":"A Malachite Green Colorimetric Assay\nfor Protein Phosphatase Activity","volume":"192","author":"Geladopoulos","year":"1991","journal-title":"Anal. Biochem."},{"issue":"5926","key":"2026101414092839100_cit59","doi-asserted-by":"publisher","first-page":"513","DOI":"10.1126\/science.1168120","article-title":"Catalytic Core of a Membrane-Associated\nEukaryotic Polyphosphate Polymerase","volume":"324","author":"Hothorn","year":"2009","journal-title":"Science"},{"key":"2026101414092839100_cit60","doi-asserted-by":"publisher","first-page":"71","DOI":"10.1016\/j.ab.2018.09.021","article-title":"Analytical Polyphosphate Extraction from Saccharomyces\nCerevisiae","volume":"563","author":"Christ","year":"2018","journal-title":"Anal. Biochem."},{"issue":"3","key":"2026101414092839100_cit61","doi-asserted-by":"publisher","first-page":"foz011","DOI":"10.1093\/femsyr\/foz011","article-title":"Saccharomyces Cerevisiae\nContaining 28% Polyphosphate\nand Production of a Polyphosphate-Rich Yeast Extract Thereof","volume":"19","author":"Christ","year":"2019","journal-title":"FEMS Yeast Res."},{"issue":"12","key":"2026101414092839100_cit62","doi-asserted-by":"publisher","first-page":"4665","DOI":"10.1021\/es100191h","article-title":"Fluorometric Quantification of Natural Inorganic Polyphosphate","volume":"44","author":"Diaz","year":"2010","journal-title":"Environ. Sci. Technol."},{"issue":"1","key":"2026101414092839100_cit63","doi-asserted-by":"publisher","first-page":"273","DOI":"10.1128\/AEM.02592-12","article-title":"Fluorometric\nQuantification of Polyphosphate in Environmental\nPlankton Samples: Extraction Protocols, Matrix Effects, and Nucleic\nAcid Interference","volume":"79","author":"Martin","year":"2013","journal-title":"Appl. Environ. Microbiol."},{"issue":"2","key":"2026101414092839100_cit64","doi-asserted-by":"publisher","first-page":"280","DOI":"10.1016\/0003-2697(87)90452-0","article-title":"Preparation of Standards and Determination of Sizes\nof Long-Chain Polyphosphates by Gel Electrophoresis","volume":"161","author":"Clark","year":"1987","journal-title":"Anal. Biochem."},{"issue":"15\u201316","key":"2026101414092839100_cit65","doi-asserted-by":"publisher","first-page":"1197","DOI":"10.1002\/elps.202300055","article-title":"Short-Chain\nPolyphosphates: Extraction Effects on Migration and Size Estimation\nof Saccharomyces Cerevisiae Extracts with Polyacrylamide Gel Electrophoresis","volume":"44","author":"Manoukian","year":"2023","journal-title":"Electrophoresis"},{"issue":"22","key":"2026101414092839100_cit66","doi-asserted-by":"publisher","first-page":"5635","DOI":"10.1039\/C4AN01179A","article-title":"Polymer\nSieving Matrices in Microanalytical Electrophoresis","volume":"139","author":"Chung","year":"2014","journal-title":"Analyst"},{"issue":"3","key":"2026101414092839100_cit67","doi-asserted-by":"publisher","first-page":"421","DOI":"10.1002\/elps.200390052","article-title":"Sieving\nMechanisms in Polymeric Matrices","volume":"24","author":"Sartori","year":"2003","journal-title":"Electrophoresis"},{"issue":"10","key":"2026101414092839100_cit68","doi-asserted-by":"publisher","first-page":"3732","DOI":"10.1039\/C9AN02553G","article-title":"Ferguson\nAnalysis of Protein Electromigration during\nSingle-Cell Electrophoresis in an Open Microfluidic Device","volume":"145","author":"Tan","year":"2020","journal-title":"Analyst"},{"issue":"1","key":"2026101414092839100_cit69","doi-asserted-by":"publisher","first-page":"215","DOI":"10.1016\/0003-9861(89)90366-4","article-title":"Nuclear Polyphosphate\nas a Possible\nSource of Energy during the Sporulation of Physarum Polycephalum","volume":"275","author":"Pilatus","year":"1989","journal-title":"Arch. Biochem. Biophys."}],"container-title":["Journal of the American\nChemical Society"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/jacs.6c14037","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/jacsat\/article-pdf\/148\/40\/43649\/68738867\/jacs.6c14037.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/pubs.acs.org\/jacsat\/article-pdf\/148\/40\/43649\/68738867\/jacs.6c14037.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T18:13:53Z","timestamp":1792001633000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/jacsat\/article\/148\/40\/43649\/5444162\/Far-Red-Turn-On-Fluorogenic-Probe-for-Versatile"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10,2]]},"references-count":69,"journal-issue":{"issue":"40","published-online":{"date-parts":[[2026,10,2]]},"published-print":{"date-parts":[[2026,10,14]]}},"URL":"https:\/\/doi.org\/10.1021\/jacs.6c14037","relation":{},"ISSN":["0002-7863","1520-5126"],"issn-type":[{"value":"0002-7863","type":"print"},{"value":"1520-5126","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,10,2]]}}}