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Here we report the multiple accumulation of cationic porphyrins in water using a polyaromatic capsule formed from bent amphiphiles. Simple stirring of the aqueous capsule with cationic Au(III)-tetraphenylporphyrins in water leads to the efficient formation of new host\u2013guest composites, much more efficiently than that with nonionic Zn(II) derivatives under the same conditions. The detailed UV\u2013visible, NMR, DLS, AFM, TEM, and molecular modeling studies reveal that the accumulated multication composite is a \u223c2 nm-sized spherical particle, consisting of stacked, three porphyrin cations in the capsule as a major product, through effective host\u2013guest \u03c0\u2013\u03c0 and CH\u2212\u03c0 interactions. The theoretical analysis indicates the importance of large dispersion force-based stabilization between the cationic porphyrins. Notably, the cationic Au(III)-porphyrins and nonionic polyaromatic compounds such as Cu(II)-phthalocyanine and fullerene are co-accumulated efficiently in the cavity through a stepwise grinding-stirring protocol. Otherwise unstable multicationic accumulation as well as unusual cationic-nonionic co-accumulation are demonstrated in the adaptable cavity of the polyaromatic capsule even under hydratable aqueous conditions.<\/jats:p>","DOI":"10.1021\/jacsau.6c00880","type":"journal-article","created":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T10:48:47Z","timestamp":1788259727000},"page":"5225-5231","source":"Crossref","is-referenced-by-count":2,"title":["Aqueous Accumulation\nand Co-Accumulation of Multiple\nCationic Porphyrins within a Polyaromatic Capsule"],"prefix":"10.1021","volume":"6","author":[{"given":"Kazuki","family":"Toyama","sequence":"first","affiliation":[{"name":"Institute of Science Tokyo , , 4259 Nagatsuta , Midori-ku, ,","place":["Yokohama, Japan, 226-8501"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0674-660X","authenticated-orcid":true,"given":"Yuya","family":"Tanaka","sequence":"additional","affiliation":[{"name":"Institute of Science Tokyo , , 4259 Nagatsuta , Midori-ku, ,","place":["Yokohama, Japan, 226-8501"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yohei","family":"Haketa","sequence":"additional","affiliation":[{"name":"Ritsumeikan University , , 1-1-1 Nojihigashi , ,","place":["Kusatsu, Japan, 525-8577"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroki","family":"Horita","sequence":"additional","affiliation":[{"name":"Ritsumeikan University , , 1-1-1 Nojihigashi , ,","place":["Kusatsu, Japan, 525-8577"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9928-1655","authenticated-orcid":true,"given":"Hiromitsu","family":"Maeda","sequence":"additional","affiliation":[{"name":"Ritsumeikan University , , 1-1-1 Nojihigashi , ,","place":["Kusatsu, Japan, 525-8577"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0543-3943","authenticated-orcid":true,"given":"Michito","family":"Yoshizawa","sequence":"additional","affiliation":[{"name":"Institute of Science Tokyo , , 4259 Nagatsuta , Midori-ku, ,","place":["Yokohama, Japan, 226-8501"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2026,8,26]]},"reference":[{"key":"2026092808085381700_cit1","doi-asserted-by":"crossref","DOI":"10.1002\/3527607439","volume-title":"Supramolecular\nChemistry: Concepts and Perspectives","author":"Lehn","year":"1995"},{"key":"2026092808085381700_cit1b","volume-title":"Molecular\nSelf-Assembly: Organic Versus Inorganic Approaches","author":"Fujita","year":"2000"},{"key":"2026092808085381700_cit2","doi-asserted-by":"publisher","first-page":"4585","DOI":"10.1021\/cr040087x","article-title":"Ion Pairing","volume":"106","author":"Marcus","year":"2006","journal-title":"Chem. 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