{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,18]],"date-time":"2026-03-18T22:16:22Z","timestamp":1773872182161,"version":"3.50.1"},"reference-count":47,"publisher":"American Chemical Society (ACS)","issue":"2","license":[{"start":{"date-parts":[[2020,12,31]],"date-time":"2020-12-31T00:00:00Z","timestamp":1609372800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2020,12,31]],"date-time":"2020-12-31T00:00:00Z","timestamp":1609372800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2020,12,31]],"date-time":"2020-12-31T00:00:00Z","timestamp":1609372800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/501100002855","name":"Ministry of Science and Technology of the People's Republic of China","doi-asserted-by":"publisher","award":["2018ZX09711001-002-003"],"award-info":[{"award-number":["2018ZX09711001-002-003"]}],"id":[{"id":"10.13039\/501100002855","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002855","name":"Ministry of Science and Technology of the People's Republic of China","doi-asserted-by":"publisher","award":["2018ZX09711002-001-004"],"award-info":[{"award-number":["2018ZX09711002-001-004"]}],"id":[{"id":"10.13039\/501100002855","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002857","name":"China Pharmaceutical University","doi-asserted-by":"publisher","award":["CPU2018GF09"],"award-info":[{"award-number":["CPU2018GF09"]}],"id":[{"id":"10.13039\/501100002857","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002857","name":"China Pharmaceutical University","doi-asserted-by":"publisher","award":["CPU2018GY09"],"award-info":[{"award-number":["CPU2018GY09"]}],"id":[{"id":"10.13039\/501100002857","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004608","name":"Natural Science Foundation of Jiangsu Province","doi-asserted-by":"publisher","award":["BK20180079"],"award-info":[{"award-number":["BK20180079"]}],"id":[{"id":"10.13039\/501100004608","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81720108032"],"award-info":[{"award-number":["81720108032"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81872838"],"award-info":[{"award-number":["81872838"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81930109"],"award-info":[{"award-number":["81930109"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100013313","name":"Overseas Expertise Introduction Project for Discipline Innovation","doi-asserted-by":"crossref","award":["G20582017001"],"award-info":[{"award-number":["G20582017001"]}],"id":[{"id":"10.13039\/501100013313","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Am. Soc. Mass Spectrom."],"published-print":{"date-parts":[[2021,2,3]]},"DOI":"10.1021\/jasms.0c00382","type":"journal-article","created":{"date-parts":[[2020,12,31]],"date-time":"2020-12-31T17:13:18Z","timestamp":1609434798000},"page":"519-530","source":"Crossref","is-referenced-by-count":3,"title":["Time-Resolved Acetaldehyde-Based Accessibility Profiling Maps Ligand\u2013Target Interactions"],"prefix":"10.1021","volume":"32","author":[{"given":"Yang","family":"Tian","sequence":"first","affiliation":[{"name":"Department of Pharmacology, School of Pharmacy, China Pharmaceutical University, Tongjiaxiang #24, Nanjing, Jiangsu 210009, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qiuyu","family":"Bao","sequence":"additional","affiliation":[{"name":"Jiangsu Provincial Key Laboratory of Drug Metabolism and Pharmacokinetics, State Key Laboratory of Natural Medicines, China Pharmaceutical University, Tongjiaxiang #24, Nanjing, Jiangsu 210009, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nian","family":"Wang","sequence":"additional","affiliation":[{"name":"Jiangsu Provincial Key Laboratory of Drug Metabolism and Pharmacokinetics, State Key Laboratory of Natural Medicines, China Pharmaceutical University, Tongjiaxiang #24, Nanjing, Jiangsu 210009, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ning","family":"Wan","sequence":"additional","affiliation":[{"name":"Jiangsu Provincial Key Laboratory of Drug Metabolism and Pharmacokinetics, State Key Laboratory of Natural Medicines, China Pharmaceutical University, Tongjiaxiang #24, Nanjing, Jiangsu 210009, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Langlang","family":"Lv","sequence":"additional","affiliation":[{"name":"Jiangsu Provincial Key Laboratory of Drug Metabolism and Pharmacokinetics, State Key Laboratory of Natural Medicines, China Pharmaceutical University, Tongjiaxiang #24, Nanjing, Jiangsu 210009, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haiping","family":"Hao","sequence":"additional","affiliation":[{"name":"Jiangsu Provincial Key Laboratory of Drug Metabolism and Pharmacokinetics, State Key Laboratory of Natural Medicines, China Pharmaceutical University, Tongjiaxiang #24, Nanjing, Jiangsu 210009, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chaoyong","family":"He","sequence":"additional","affiliation":[{"name":"Department of Pharmacology, School of Pharmacy, China Pharmaceutical University, Tongjiaxiang #24, Nanjing, Jiangsu 210009, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7416-1558","authenticated-orcid":true,"given":"Hui","family":"Ye","sequence":"additional","affiliation":[{"name":"Jiangsu Provincial Key Laboratory of Drug Metabolism and Pharmacokinetics, State Key Laboratory of Natural Medicines, China Pharmaceutical University, Tongjiaxiang #24, Nanjing, Jiangsu 210009, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"316","published-online":{"date-parts":[[2020,12,31]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijbiomac.2017.07.185"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jmedchem.7b01408"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1002\/prot.10567"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.3390\/ph5101064"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1042\/bst0310973"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1002\/cbic.200500100"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1038\/s41596-019-0281-0"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1007\/s13361-016-1451-8"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1007\/s13361-011-0311-9"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1007\/s13361-014-0964-2"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1002\/mas.21462"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1021\/acs.analchem.5b02478"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1002\/mas.21565"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1002\/mas.20064"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1080\/17460441.2017.1363734"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-019-11917-z"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1002\/mas.20082"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1007\/s13361-016-1356-6"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1021\/jasms.0c00131"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1021\/acs.analchem.8b04951"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms13288"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1021\/acs.analchem.9b03827"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-biophys-070317-033123"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1021\/acs.analchem.5b01888"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1002\/mas.20203"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrev.9b00815"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.89.12.5630"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.8b05098"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1016\/S0040-4039(98)02695-1"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1016\/j.trac.2019.07.009"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1021\/acs.analchem.6b02502"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1021\/acs.analchem.7b00320"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1039\/C9CC00520J"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jproteome.9b00787"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1007\/s00216-012-6070-z"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1021\/bc050340f"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M310752200"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1021\/acs.analchem.0c01604"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1038\/nchem.2826"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1021\/ja054686c"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1016\/j.aca.2016.11.073"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1021\/ac402906d"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1016\/j.jasms.2008.05.012"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1107\/S090744499300719X"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1016\/0167-4838(95)00138-K"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1111\/j.1432-1033.1983.tb07329.x"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.1101\/2020.11.18.387670"}],"container-title":["Journal of the American Society for Mass Spectrometry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/jasms.0c00382","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,26]],"date-time":"2023-04-26T08:37:40Z","timestamp":1682498260000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/jasms.0c00382"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,12,31]]},"references-count":47,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2021,2,3]]}},"alternative-id":["10.1021\/jasms.0c00382"],"URL":"https:\/\/doi.org\/10.1021\/jasms.0c00382","relation":{},"ISSN":["1044-0305","1879-1123"],"issn-type":[{"value":"1044-0305","type":"print"},{"value":"1879-1123","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,12,31]]}}}