{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T21:10:47Z","timestamp":1789679447183,"version":"4.0.1"},"reference-count":26,"publisher":"American Chemical Society (ACS)","issue":"2","license":[{"start":{"date-parts":[[2025,1,17]],"date-time":"2025-01-17T00:00:00Z","timestamp":1737072000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100020979","name":"Provincie Limburg","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100020979","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100008897","name":"Janssen Pharmaceutica","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008897","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Am. Soc. Mass Spectrom."],"published-print":{"date-parts":[[2025,2,5]]},"DOI":"10.1021\/jasms.4c00313","type":"journal-article","created":{"date-parts":[[2025,1,17]],"date-time":"2025-01-17T22:23:19Z","timestamp":1737152599000},"page":"265-276","source":"Crossref","is-referenced-by-count":8,"title":["Investigation into Drug-Induced Liver Damage Using Multimodal Mass Spectrometry Imaging"],"prefix":"10.1021","volume":"36","author":[{"given":"Bryn","family":"Flinders","sequence":"first","affiliation":[{"name":"Maastricht MultiModal Molecular Imaging Institute (M4i), Division of Imaging Mass Spectrometry, Maastricht University, Universiteitssingel 50, 6229 ER Maastricht, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lennart","family":"Huizing","sequence":"additional","affiliation":[{"name":"Maastricht MultiModal Molecular Imaging Institute (M4i), Division of Imaging Mass Spectrometry, Maastricht University, Universiteitssingel 50, 6229 ER Maastricht, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bhanu","family":"Singh","sequence":"additional","affiliation":[{"name":"Janssen Research & Development, 1400 McKean Rd, Spring House, Pennsylvania 19477, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heng-Keang","family":"Lim","sequence":"additional","affiliation":[{"name":"Janssen Research & Development, 1400 McKean Rd, Spring House, Pennsylvania 19477, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marjolein","family":"van Heerden","sequence":"additional","affiliation":[{"name":"Janssen Research & Development, Turnhoutseweg 30, 2340 Beerse, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4956-1418","authenticated-orcid":true,"given":"Filip","family":"Cuyckens","sequence":"additional","affiliation":[{"name":"Janssen Research & Development, Turnhoutseweg 30, 2340 Beerse, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6533-7179","authenticated-orcid":true,"given":"Ron M. A.","family":"Heeren","sequence":"additional","affiliation":[{"name":"Maastricht MultiModal Molecular Imaging Institute (M4i), Division of Imaging Mass Spectrometry, Maastricht University, Universiteitssingel 50, 6229 ER Maastricht, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3568-1371","authenticated-orcid":true,"given":"Rob J.","family":"Vreeken","sequence":"additional","affiliation":[{"name":"Maastricht MultiModal Molecular Imaging Institute (M4i), Division of Imaging Mass Spectrometry, Maastricht University, Universiteitssingel 50, 6229 ER Maastricht, The Netherlands"},{"name":"Janssen Research & Development, Turnhoutseweg 30, 2340 Beerse, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2025,1,17]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhealeco.2016.01.012"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.2133\/dmpk.DMPK-10-RV-062"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1208\/s12248-009-9158-4"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1021\/ac8015467"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1021\/ac1029049"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijms.2018.02.007"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijms.2014.05.012"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0047353"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1007\/s13361-015-1254-3"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1177\/0192623315617033"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1007\/s13361-015-1103-4"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1016\/j.taap.2021.115578"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1002\/rcm.7379"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1002\/rcm.4230"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1021\/acs.analchem.7b01168"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1021\/acs.analchem.8b01378"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1021\/ac100818g"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0188394"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1007\/s13361-017-1886-6"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1021\/acs.analchem.8b02910"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-4159.2010.06836.x"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1021\/acs.analchem.2c03745"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1002\/rcm.1737"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1021\/acs.analchem.6b04047"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1002\/cld.148"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinre.2015.12.017"}],"container-title":["Journal of the American Society for Mass Spectrometry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/jasms.4c00313","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/jasms.4c00313","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,6]],"date-time":"2025-02-06T10:23:58Z","timestamp":1738837438000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/jasms.4c00313"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1,17]]},"references-count":26,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2025,2,5]]}},"alternative-id":["10.1021\/jasms.4c00313"],"URL":"https:\/\/doi.org\/10.1021\/jasms.4c00313","relation":{},"ISSN":["1044-0305","1879-1123"],"issn-type":[{"value":"1044-0305","type":"print"},{"value":"1879-1123","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,1,17]]}}}