{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,5]],"date-time":"2026-01-05T22:13:26Z","timestamp":1767651206941},"reference-count":31,"publisher":"American Chemical Society (ACS)","issue":"19","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Med. Chem."],"published-print":{"date-parts":[[2000,9,1]]},"DOI":"10.1021\/jm000087z","type":"journal-article","created":{"date-parts":[[2002,7,26]],"date-time":"2002-07-26T05:59:58Z","timestamp":1027663198000},"page":"3549-3557","source":"Crossref","is-referenced-by-count":28,"title":["Thiazoloindans and Thiazolobenzopyrans:\u2009 A Novel Class of Orally Active Central Dopamine (Partial) Agonists"],"prefix":"10.1021","volume":"43","author":[{"given":"L. Alexander","family":"van Vliet","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nienke","family":"Rodenhuis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H\u00e5kan","family":"Wikstr\u00f6m","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas A.","family":"Pugsley","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kevin A.","family":"Serpa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leonard T.","family":"Meltzer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas G.","family":"Heffner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lawrence D.","family":"Wise","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mary E.","family":"Lajiness","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rita M.","family":"Huff","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kjell","family":"Svensson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guido R. M. M.","family":"Haenen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aalt","family":"Bast","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"316","published-online":{"date-parts":[[2000,8,26]]},"reference":[{"key":"jm000087zb00001\/jm000087zb00001_1","first-page":"33","volume":"126","author":"Halliwell B","year":"1989","journal-title":"Acta Neurol. Scand. Suppl."},{"key":"jm000087zb00002\/jm000087zb00002_1","doi-asserted-by":"crossref","first-page":"1623","DOI":"10.1111\/j.1471-4159.1992.tb10990.x","volume":"59","author":"Halliwell B","year":"1992","journal-title":"J. Neurochem."},{"key":"jm000087zb00003\/jm000087zb00003_1","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1016\/S0891-5849(99)00075-1","volume":"27","author":"Martignoni E.","year":"1999","journal-title":"Free Radical Biol. Med."},{"key":"jm000087zb00004\/jm000087zb00004_1","first-page":"210","volume":"56","author":"Gassen M.","year":"1999","journal-title":"J. Neural Transm. Suppl."},{"key":"jm000087zb00005\/jm000087zb00005_1","doi-asserted-by":"crossref","first-page":"S38","DOI":"10.1212\/WNL.49.1_Suppl_1.S34","volume":"49","author":"Watts R. L","year":"1997","journal-title":"Neurology"},{"key":"jm000087zb00006\/jm000087zb00006_1","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1111\/j.1600-0773.1983.tb01075.x","volume":"52","author":"And\u00e9n N. E.","year":"1983","journal-title":"Acta Pharmacol. Toxicol. Copenh."},{"key":"jm000087zb00007\/jm000087zb00007_1","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1021\/jm00163a052","volume":"33","author":"Jaen J. C.","year":"1990","journal-title":"J. Med. Chem."},{"key":"jm000087zb00008\/jm000087zb00008_1","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/0922-4106(95)90013-6","volume":"290","author":"Mierau J.","year":"1995","journal-title":"Eur. J. Pharmacol."},{"key":"jm000087zb00009\/jm000087zb00009_1","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1021\/jm00386a009","volume":"30","author":"Schneider C. S.","year":"1987","journal-title":"J. Med. Chem."},{"key":"jm000087zb00010\/jm000087zb00010_1","first-page":"1250","volume":"39","author":"Bonne C.","year":"1989","journal-title":"Arzneimittelforschung"},{"key":"jm000087zb00011\/jm000087zb00011_1","first-page":"88","volume":"742","author":"Hall E. D.","year":"1996","journal-title":"Brain Res."},{"key":"jm000087zb00012\/jm000087zb00012_1","first-page":"5816","volume":"73","author":"Maggiolo A","year":"1951","journal-title":"J. Am. Chem. Soc."},{"key":"jm000087zb00013\/jm000087zb00013_1","first-page":"866","volume":"25","author":"Sugihara H.","year":"1977","journal-title":"Chem. Pharm. Bull."},{"key":"jm000087zb00014\/jm000087zb00014_1","first-page":"2216","volume":"38","author":"Stjernl\u00f6f P.","year":"1995","journal-title":"J. Med. Chem."},{"key":"jm000087zb00015\/jm000087zb00015_1","first-page":"749","volume":"23","author":"Cannon J. G.","year":"1980","journal-title":"J. Med. Chem."},{"key":"jm000087zb00016\/jm000087zb00016_1","first-page":"28","volume":"159","author":"Haenen G. R. M. M.","year":"1983","journal-title":"FEBS Lett."},{"key":"jm000087zb00017\/jm000087zb00017_1","first-page":"1581","volume":"267","author":"Lajiness M. E.","year":"1993","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"jm000087zb00018\/jm000087zb00018_1","first-page":"60","volume":"45","author":"Chio C. L.","year":"1994","journal-title":"Mol. Pharmacol."},{"key":"jm000087zb00019\/jm000087zb00019_1","first-page":"93","volume":"367","author":"Ungerstedt U","year":"1971","journal-title":"Acta Physiol. Scand. Suppl."},{"key":"jm000087zb00020\/jm000087zb00020_1","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1016\/0006-8993(70)90187-3","volume":"24","author":"Ungerstedt U.","year":"1970","journal-title":"Brain Res."},{"key":"jm000087zb00021\/jm000087zb00021_1","first-page":"691","volume":"31","author":"Wise L. D.","year":"1988","journal-title":"J. Med. Chem."},{"key":"jm000087zb00022\/jm000087zb00022_1","first-page":"434","volume":"24","author":"Hacksell U.","year":"1981","journal-title":"J. Med. Chem."},{"key":"jm000087zb00023\/jm000087zb00023_1","doi-asserted-by":"crossref","first-page":"4237","DOI":"10.1021\/jm960345l","volume":"39","author":"van Vliet L. A.","year":"1996","journal-title":"J. Med. Chem."},{"key":"jm000087zb00024\/jm000087zb00024_1","unstructured":"Pallas version 1.2 is commercially available software of CompuDrug Chemistry Ltd., 1994."},{"key":"jm000087zb00025\/jm000087zb00025_1","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1007\/BF01249001","volume":"57","author":"Carlsson A.","year":"1983","journal-title":"J. Neural Transm."},{"key":"jm000087zb00026\/jm000087zb00026_1","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1007\/BF00428999","volume":"81","author":"Hjorth S.","year":"1983","journal-title":"Psychopharmacology (Berl.)"},{"key":"jm000087zb00027\/jm000087zb00027_1","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1007\/BF01244979","volume":"94","author":"Waters N.","year":"1993","journal-title":"J. Neural Transm. Gen. Sect."},{"key":"jm000087zb00028\/jm000087zb00028_1","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1007\/BF01283032","volume":"95","author":"Svensson K.","year":"1994","journal-title":"J. Neural Transm. Gen. Sect."},{"key":"jm000087zb00029\/jm000087zb00029_1","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1016\/0014-2999(93)90674-7","volume":"249","author":"Meller E.","year":"1993","journal-title":"Eur. J. Pharmacol."},{"key":"jm000087zb00030\/jm000087zb00030_1","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1016\/0014-2999(88)90715-7","volume":"152","author":"Hjorth S.","year":"1988","journal-title":"Eur. J. Pharmacol."},{"key":"jm000087zb00031\/jm000087zb00031_1","author":"van Vliet L. A.","year":"2000","journal-title":"J. Med. Chem."}],"container-title":["Journal of Medicinal Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/jm000087z","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,3]],"date-time":"2024-01-03T07:08:41Z","timestamp":1704265721000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/jm000087z"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2000,8,26]]},"references-count":31,"journal-issue":{"issue":"19","published-print":{"date-parts":[[2000,9,1]]}},"alternative-id":["10.1021\/jm000087z"],"URL":"https:\/\/doi.org\/10.1021\/jm000087z","relation":{},"ISSN":["0022-2623","1520-4804"],"issn-type":[{"value":"0022-2623","type":"print"},{"value":"1520-4804","type":"electronic"}],"subject":[],"published":{"date-parts":[[2000,8,26]]}}}