{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,25]],"date-time":"2026-03-25T21:35:24Z","timestamp":1774474524335,"version":"3.50.1"},"reference-count":0,"publisher":"American Chemical Society (ACS)","issue":"8","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Med. Chem."],"published-print":{"date-parts":[[1986,8]]},"DOI":"10.1021\/jm00158a028","type":"journal-article","created":{"date-parts":[[2005,3,18]],"date-time":"2005-03-18T10:50:23Z","timestamp":1111143023000},"page":"1488-1494","source":"Crossref","is-referenced-by-count":42,"title":["N-Substituted sulfonamide carbonic anhydrase inhibitors with topical effects on intraocular pressure"],"prefix":"10.1021","volume":"29","author":[{"given":"Michael W.","family":"Duffel","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"I. Silwai","family":"Ing","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tyrone M.","family":"Segarra","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John A.","family":"Dixson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Charles F.","family":"Barfknecht","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ronald D.","family":"Schoenwald","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"316","published-online":{"date-parts":[[2002,5,1]]},"container-title":["Journal of Medicinal Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/jm00158a028","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,3,24]],"date-time":"2023-03-24T09:32:01Z","timestamp":1679650321000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/abs\/10.1021\/jm00158a028"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1986,8]]},"references-count":0,"journal-issue":{"issue":"8","published-print":{"date-parts":[[1986,8,1]]}},"alternative-id":["10.1021\/jm00158a028"],"URL":"https:\/\/doi.org\/10.1021\/jm00158a028","relation":{},"ISSN":["0022-2623","1520-4804"],"issn-type":[{"value":"0022-2623","type":"print"},{"value":"1520-4804","type":"electronic"}],"subject":[],"published":{"date-parts":[[1986,8]]}}}