{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,17]],"date-time":"2026-04-17T12:35:27Z","timestamp":1776429327951,"version":"3.51.2"},"reference-count":41,"publisher":"American Chemical Society (ACS)","issue":"22","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Med. Chem."],"published-print":{"date-parts":[[2004,10,1]]},"DOI":"10.1021\/jm040139a","type":"journal-article","created":{"date-parts":[[2004,10,14]],"date-time":"2004-10-14T04:37:24Z","timestamp":1097728644000},"page":"5347-5355","source":"Crossref","is-referenced-by-count":5,"title":["The Anthrax Protective Antigen (PA<sub>63<\/sub>) Bound Conformation of a Peptide Inhibitor of the Binding of Lethal Factor to PA<sub>63<\/sub>:\u2009 As Determined by trNOESY NMR and Molecular Modeling"],"prefix":"10.1021","volume":"47","author":[{"given":"Rickey P.","family":"Hicks","sequence":"first","affiliation":[{"name":"Department of Medicinal Chemistry, Division of Experimental Therapeutics, Walter Reed Army Institute of Research, 503 Robert Grant Avenue, Silver Spring, Maryland 20910, and Naval Academy Preparatory School, Newport, Rhode Island"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Apurba K.","family":"Bhattacharjee","sequence":"additional","affiliation":[{"name":"Department of Medicinal Chemistry, Division of Experimental Therapeutics, Walter Reed Army Institute of Research, 503 Robert Grant Avenue, Silver Spring, Maryland 20910, and Naval Academy Preparatory School, Newport, Rhode Island"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brandon W.","family":"Koser","sequence":"additional","affiliation":[{"name":"Department of Medicinal Chemistry, Division of Experimental Therapeutics, Walter Reed Army Institute of Research, 503 Robert Grant Avenue, Silver Spring, Maryland 20910, and Naval Academy Preparatory School, Newport, Rhode Island"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel D.","family":"Traficante","sequence":"additional","affiliation":[{"name":"Department of Medicinal Chemistry, Division of Experimental Therapeutics, Walter Reed Army Institute of Research, 503 Robert Grant Avenue, Silver Spring, Maryland 20910, and Naval Academy Preparatory School, Newport, Rhode Island"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"316","published-online":{"date-parts":[[2004,9,18]]},"reference":[{"key":"jm040139ab00001\/jm040139ab00001_1","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1016\/S0014-5793(02)03609-8","volume":"531","author":"Ascenzi P.","year":"2002","journal-title":"FEBS Lett."},{"key":"jm040139ab00002\/jm040139ab00002_1","doi-asserted-by":"crossref","first-page":"958","DOI":"10.1038\/nbt1001-958","author":"Mourez M.","year":"2001","journal-title":"Nat. Biotechnol."},{"key":"jm040139ab00003\/jm040139ab00003_1","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1016\/S0300-9084(00)00216-9","volume":"82","author":"Humeau Y.","year":"2000","journal-title":"Biochimie"},{"key":"jm040139ab00004\/jm040139ab00004_1","doi-asserted-by":"crossref","first-page":"699","DOI":"10.1038\/78005","volume":"7","author":"Swaminathan S.","year":"2000","journal-title":"Nat. Struct. Biol."},{"key":"jm040139ab00005\/jm040139ab00005_1","doi-asserted-by":"crossref","first-page":"15746","DOI":"10.1021\/bi981436i","volume":"37","author":"Wesche J.","year":"1998","journal-title":"Biochemistry"},{"key":"jm040139ab00006\/jm040139ab00006_1","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1016\/S0165-6147(02)02127-2","volume":"23","author":"Stubbs M. T.","year":"2002","journal-title":"TRENDS Pharmacol. Sci."},{"key":"jm040139ab00007\/jm040139ab00007_1","doi-asserted-by":"crossref","first-page":"826","DOI":"10.1056\/NEJM199909093411107","volume":"341","author":"Dixon T. C.","year":"1999","journal-title":"Engl. J. Med."},{"key":"jm040139ab00008\/jm040139ab00008_1","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1016\/S0966-842X(02)02369-7","volume":"10","author":"Mourez M.","year":"2002","journal-title":"Trends Microbiol."},{"key":"jm040139ab00009\/jm040139ab00009_1","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1046\/j.1365-2672.1999.00893.x","volume":"87","author":"Vitale G.","year":"1998","journal-title":"J. Appl. Microbiol."},{"key":"jm040139ab00010\/jm040139ab00010_1","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1126\/science.280.5364.734","volume":"280","author":"Duesbery N. S.","year":"1998","journal-title":"Science"},{"key":"jm040139ab00011\/jm040139ab00011_1","doi-asserted-by":"crossref","first-page":"838","DOI":"10.1038\/385833a0","volume":"385","author":"Petosa C.","year":"1997","journal-title":"Nature"},{"key":"jm040139ab00012\/jm040139ab00012_1","first-page":"20612","volume":"269","author":"Milne J. C.","year":"1994","journal-title":"J. Biol. Chem."},{"key":"jm040139ab00013\/jm040139ab00013_1","first-page":"606","volume":"26","author":"Ni F","year":"1994","journal-title":"Prog. Nucl. Magn. Reson. Spectrosc."},{"key":"jm040139ab00014\/jm040139ab00014_1","first-page":"2099","volume":"43","author":"Mayer M.","year":"2000","journal-title":"J. Med. Chem."},{"key":"jm040139ab00015\/jm040139ab00015_1","doi-asserted-by":"crossref","unstructured":"Feeney, J.; Birdsall, B. NMR studies of protein\u2212ligand interactions.NMR of Macromolecules. A practical Approach; IRL Press (Oxford University Press):\u2009 Oxford, 1993; pp 183\u2212212.","DOI":"10.1093\/oso\/9780199632251.003.0007"},{"key":"jm040139ab00016\/jm040139ab00016_1","first-page":"232","volume":"60","author":"Craik D. J.","year":"1997","journal-title":"Methods Mol. Biol."},{"key":"jm040139ab00017\/jm040139ab00017_1","doi-asserted-by":"crossref","first-page":"6791","DOI":"10.1021\/bi00188a006","volume":"33","author":"Jarori G. K.","year":"1994","journal-title":"Biochemistry"},{"key":"jm040139ab00018\/jm040139ab00018_1","doi-asserted-by":"crossref","first-page":"12948","DOI":"10.1021\/bi00210a049","volume":"32","author":"Murali N.","year":"1993","journal-title":"Biochemistry"},{"key":"jm040139ab00019\/jm040139ab00019_1","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1111\/j.1432-1033.1997.00242.x","volume":"244","author":"Casset F.","year":"1997","journal-title":"Eur. J. Biochem."},{"key":"jm040139ab00020\/jm040139ab00020_1","first-page":"168","volume":"176","author":"Bax A","year":"1989","journal-title":"Methods Enzymol."},{"key":"jm040139ab00021\/jm040139ab00021_1","first-page":"355","volume":"65","author":"Bax A.","year":"1985","journal-title":"J. Magn. Reson."},{"key":"jm040139ab00022\/jm040139ab00022_1","doi-asserted-by":"crossref","first-page":"3731","DOI":"10.1021\/ja00377a036","volume":"104","author":"Eich G.","year":"1982","journal-title":"J. Am. Chem. Soc."},{"key":"jm040139ab00023\/jm040139ab00023_1","first-page":"286","volume":"48","author":"States D. J.","year":"1982","journal-title":"J. Magn. Reson."},{"key":"jm040139ab00024\/jm040139ab00024_1","doi-asserted-by":"crossref","first-page":"740","DOI":"10.1016\/0022-2836(84)90034-2","volume":"180","author":"Wuthrich K.","year":"1984","journal-title":"J. Mol. Biol."},{"key":"jm040139ab00025\/jm040139ab00025_1","first-page":"623","volume":"34","author":"Young J. K.","year":"1994","journal-title":"Biopolymers"},{"key":"jm040139ab00026\/jm040139ab00026_1","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1038\/nbt0202-118","volume":"20","author":"Glick M.","year":"2002","journal-title":"Nature Biotechnol."},{"key":"jm040139ab00027\/jm040139ab00027_1","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1016\/0014-5793(95)01192-H","volume":"375","author":"Anglister J.","year":"1995","journal-title":"FEBS Lett."},{"key":"jm040139ab00028\/jm040139ab00028_1","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1016\/0022-2836(91)90219-V","volume":"222","author":"Campbell A. P.","year":"1991","journal-title":"J. Mol. Biol."},{"key":"jm040139ab00029\/jm040139ab00029_1","first-page":"402","volume":"48","author":"Clore G. M.","year":"1982","journal-title":"J. Magn. Reson."},{"key":"jm040139ab00030\/jm040139ab00030_1","doi-asserted-by":"crossref","first-page":"9423","DOI":"10.1021\/bi00087a022","volume":"32","author":"Lippens G.","year":"1993","journal-title":"Biochemistry"},{"key":"jm040139ab00031\/jm040139ab00031_1","doi-asserted-by":"crossref","first-page":"13681","DOI":"10.1021\/bi00041a049","volume":"34","author":"Weimar T.","year":"1995","journal-title":"Biochemistry"},{"key":"jm040139ab00032\/jm040139ab00032_1","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1006\/jmra.1993.1098","volume":"102","author":"Sklenar M.","year":"1993","journal-title":"J. Magn. Reson., Ser. A"},{"key":"jm040139ab00033\/jm040139ab00033_1","unstructured":"Accelrys, I. 9685 Scranton Road, San Diego, CA 92121-3752."},{"key":"jm040139ab00034\/jm040139ab00034_1","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1146\/annurev.bb.20.060191.000333","volume":"20","author":"Clore G. M.","year":"1991","journal-title":"Annu. Rev. Biophys. Biophys. Chem."},{"key":"jm040139ab00035\/jm040139ab00035_1","doi-asserted-by":"crossref","first-page":"1506","DOI":"10.1021\/jm970789x","volume":"41","author":"Whitehead T. L.","year":"1998","journal-title":"J. Med. Chem."},{"key":"jm040139ab00036\/jm040139ab00036_1","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1021\/ac00200a003","volume":"62","author":"Gronenborn A. M.","year":"1990","journal-title":"Anal. Chem."},{"key":"jm040139ab00037\/jm040139ab00037_1","doi-asserted-by":"crossref","first-page":"1101","DOI":"10.1021\/j100108a002","volume":"97","author":"Honig B.","year":"1993","journal-title":"J. Phys. Chem."},{"key":"jm040139ab00038\/jm040139ab00038_1","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1002\/prot.340040104","volume":"4","author":"Gilson M.","year":"1988","journal-title":"Protiens"},{"key":"jm040139ab00039\/jm040139ab00039_1","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1080\/08927029408021998","volume":"13","author":"Schmidt A. B.","year":"1994","journal-title":"Mol. Simul."},{"key":"jm040139ab00040\/jm040139ab00040_1","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1002\/jcc.540120405","volume":"12","author":"Nicholls A.","year":"1991","journal-title":"J. Comput. Chem."},{"key":"jm040139ab00041\/jm040139ab00041_1","doi-asserted-by":"crossref","first-page":"954","DOI":"10.1016\/S0006-3495(88)83175-8","volume":"53","author":"Behling R. W.","year":"1988","journal-title":"Biophys. J."}],"container-title":["Journal of Medicinal Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/jm040139a","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,14]],"date-time":"2024-01-14T16:56:47Z","timestamp":1705251407000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/jm040139a"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,9,18]]},"references-count":41,"journal-issue":{"issue":"22","published-print":{"date-parts":[[2004,10,1]]}},"alternative-id":["10.1021\/jm040139a"],"URL":"https:\/\/doi.org\/10.1021\/jm040139a","relation":{},"ISSN":["0022-2623","1520-4804"],"issn-type":[{"value":"0022-2623","type":"print"},{"value":"1520-4804","type":"electronic"}],"subject":[],"published":{"date-parts":[[2004,9,18]]}}}