{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,14]],"date-time":"2026-04-14T23:34:48Z","timestamp":1776209688702,"version":"3.50.1"},"reference-count":24,"publisher":"American Chemical Society (ACS)","issue":"20","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Med. Chem."],"published-print":{"date-parts":[[2006,10,1]]},"DOI":"10.1021\/jm050054p","type":"journal-article","created":{"date-parts":[[2006,6,10]],"date-time":"2006-06-10T17:32:46Z","timestamp":1149960766000},"page":"5869-5879","source":"Crossref","is-referenced-by-count":44,"title":["Molecular Complexity Analysis of de Novo Designed Ligands"],"prefix":"10.1021","volume":"49","author":[{"given":"Krisztina","family":"Boda","sequence":"first","affiliation":[{"name":"ICAMS, School of Chemistry, University of Leeds, LS2 9JT, U.K."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A. Peter","family":"Johnson","sequence":"additional","affiliation":[{"name":"ICAMS, School of Chemistry, University of Leeds, LS2 9JT, U.K."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"316","published-online":{"date-parts":[[2006,1,26]]},"reference":[{"key":"jm050054pb00001\/jm050054pb00001_1","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1002\/med.10041","volume":"23","author":"Muegge I","year":"2003","journal-title":"Med. Res. Rev."},{"key":"jm050054pb00002\/jm050054pb00002_1","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/S0169-409X(02)00003-0","volume":"54","author":"Walters W. P.","year":"2002","journal-title":"Adv. Drug Delivery Rev."},{"key":"jm050054pb00003\/jm050054pb00003_1","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1016\/S1359-6446(97)01163-X","volume":"3","author":"Walters W. P.","year":"1998","journal-title":"Drug Discovery Today"},{"key":"jm050054pb00004\/jm050054pb00004_1","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/S0169-409X(00)00129-0","volume":"46","author":"Lipinski C. A.","year":"2001","journal-title":"Adv. Drug Delivery Rev."},{"key":"jm050054pb00005\/jm050054pb00005_1","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1002\/(SICI)1098-1128(199805)18:3<149::AID-MED2>3.0.CO;2-X","volume":"18","author":"Fecik R. A.","year":"1998","journal-title":"Med. Res. Rev."},{"key":"jm050054pb00006\/jm050054pb00006_1","first-page":"1187","volume":"40","author":"Xu J.","year":"2000","journal-title":"J. Chem. Inf. Comput. Sci."},{"key":"jm050054pb00007\/jm050054pb00007_1","doi-asserted-by":"crossref","first-page":"1846","DOI":"10.1021\/jm015507e","volume":"44","author":"Muegge I.","year":"2001","journal-title":"J. Med. Chem."},{"key":"jm050054pb00008\/jm050054pb00008_1","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1016\/S1359-6446(97)01083-0","volume":"2","author":"Rishton G. M","year":"1997","journal-title":"Drug Discovery Today"},{"key":"jm050054pb00009\/jm050054pb00009_1","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1021\/ci990266t","volume":"40","author":"Wagener M.","year":"2000","journal-title":"J. Chem. Inf. Comput. Sci."},{"key":"jm050054pb00010\/jm050054pb00010_1","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1021\/ci970431+","volume":"38","author":"Gillet V. J.","year":"1998","journal-title":"J. Chem. Inf. Comput. Sci."},{"key":"jm050054pb00011\/jm050054pb00011_1","doi-asserted-by":"crossref","first-page":"3324","DOI":"10.1021\/jm970666c","volume":"41","author":"Ajay","year":"1998","journal-title":"J. Med. Chem."},{"key":"jm050054pb00012\/jm050054pb00012_1","doi-asserted-by":"crossref","first-page":"3329","DOI":"10.1021\/jm9706776","volume":"41","author":"Sadowski J.","year":"1998","journal-title":"J. Med. Chem."},{"key":"jm050054pb00013\/jm050054pb00013_1","doi-asserted-by":"crossref","first-page":"2893","DOI":"10.1021\/jm9602928","volume":"39","author":"Bemis G. W.","year":"1996","journal-title":"J. Med. Chem."},{"key":"jm050054pb00014\/jm050054pb00014_1","doi-asserted-by":"crossref","first-page":"5099","DOI":"10.1021\/jm9903996","volume":"42","author":"Bemis G. W.","year":"1999","journal-title":"J. Med. Chem."},{"key":"jm050054pb00015\/jm050054pb00015_1","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1021\/cc9800071","volume":"1","author":"Ghose A. K.","year":"1999","journal-title":"J. Comb. Chem."},{"key":"jm050054pb00016\/jm050054pb00016_1","doi-asserted-by":"crossref","first-page":"522","DOI":"10.1021\/ci970429i","volume":"38","author":"Lewell X. Q.","year":"1998","journal-title":"J. Chem. Inf. Comput. Sci."},{"key":"jm050054pb00017\/jm050054pb00017_1","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1021\/ci0100806","volume":"42","author":"Sheridan R. P","year":"2002","journal-title":"J. Chem. Inf. Comput. Sci."},{"key":"jm050054pb00018\/jm050054pb00018_1","first-page":"533","volume":"1","author":"Wang J.","year":"1999","journal-title":"J. Comb. Chem."},{"key":"jm050054pb00019\/jm050054pb00019_1","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1007\/BF02174466","volume":"3","author":"Gillet V. J.","year":"1995","journal-title":"Perspect. Drug Discovery Des."},{"key":"jm050054pb00020\/jm050054pb00020_1","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1021\/ci00017a027","volume":"34","author":"Gillet V. J.","year":"1994","journal-title":"J. Chem. Inf. Comput. Sci."},{"key":"jm050054pb00021\/jm050054pb00021_1","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1021\/c160017a018","volume":"5","author":"Morgan H. L","year":"1965","journal-title":"J. Chem. Doc."},{"key":"jm050054pb00022\/jm050054pb00022_1","first-page":"4842","volume":"96","author":"Wipke W. T.","year":"1974","journal-title":"J. Am. Chem. Soc."},{"key":"jm050054pb00023\/jm050054pb00023_1","unstructured":"RxList LLC, The Top 200 Prescriptions for 2003 by Number of US Prescriptions Dispensed. url:\u2009http:\/\/www.rxlist.com\/top200.html."},{"key":"jm050054pb00024\/jm050054pb00024_1","first-page":"41834","volume":"277","author":"Baldwin J.","year":"2002","journal-title":"J. Biol. Chem."}],"container-title":["Journal of Medicinal Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/jm050054p","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,9,22]],"date-time":"2021-09-22T20:54:58Z","timestamp":1632344098000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/jm050054p"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,1,26]]},"references-count":24,"journal-issue":{"issue":"20","published-print":{"date-parts":[[2006,10,1]]}},"alternative-id":["10.1021\/jm050054p"],"URL":"https:\/\/doi.org\/10.1021\/jm050054p","relation":{},"ISSN":["0022-2623","1520-4804"],"issn-type":[{"value":"0022-2623","type":"print"},{"value":"1520-4804","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,1,26]]}}}