{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,11]],"date-time":"2026-03-11T01:30:02Z","timestamp":1773192602774,"version":"3.50.1"},"reference-count":28,"publisher":"American Chemical Society (ACS)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Med. Chem."],"published-print":{"date-parts":[[2006,1,1]]},"DOI":"10.1021\/jm050892j","type":"journal-article","created":{"date-parts":[[2006,1,5]],"date-time":"2006-01-05T05:24:37Z","timestamp":1136438677000},"page":"27-30","source":"Crossref","is-referenced-by-count":51,"title":["Anthrax Lethal Factor Protease Inhibitors:\u2009 Synthesis, SAR, and Structure-Based 3D QSAR Studies"],"prefix":"10.1021","volume":"49","author":[{"given":"Sherida L.","family":"Johnson","sequence":"first","affiliation":[{"name":"Cancer Research Center and Infectious and Inflammatory Disease Center, Burnham Institute for Medical Research, 10901 North Torrey Pines Road, La Jolla, California 92037"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dawoon","family":"Jung","sequence":"additional","affiliation":[{"name":"Cancer Research Center and Infectious and Inflammatory Disease Center, Burnham Institute for Medical Research, 10901 North Torrey Pines Road, La Jolla, California 92037"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martino","family":"Forino","sequence":"additional","affiliation":[{"name":"Cancer Research Center and Infectious and Inflammatory Disease Center, Burnham Institute for Medical Research, 10901 North Torrey Pines Road, La Jolla, California 92037"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ya","family":"Chen","sequence":"additional","affiliation":[{"name":"Cancer Research Center and Infectious and Inflammatory Disease Center, Burnham Institute for Medical Research, 10901 North Torrey Pines Road, La Jolla, California 92037"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arnold","family":"Satterthwait","sequence":"additional","affiliation":[{"name":"Cancer Research Center and Infectious and Inflammatory Disease Center, Burnham Institute for Medical Research, 10901 North Torrey Pines Road, La Jolla, California 92037"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dmitry V.","family":"Rozanov","sequence":"additional","affiliation":[{"name":"Cancer Research Center and Infectious and Inflammatory Disease Center, Burnham Institute for Medical Research, 10901 North Torrey Pines Road, La Jolla, California 92037"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alex Y.","family":"Strongin","sequence":"additional","affiliation":[{"name":"Cancer Research Center and Infectious and Inflammatory Disease Center, Burnham Institute for Medical Research, 10901 North Torrey Pines Road, La Jolla, California 92037"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maurizio","family":"Pellecchia","sequence":"additional","affiliation":[{"name":"Cancer Research Center and Infectious and Inflammatory Disease Center, Burnham Institute for Medical Research, 10901 North Torrey Pines Road, La Jolla, California 92037"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"316","published-online":{"date-parts":[[2005,12,1]]},"reference":[{"key":"jm050892jb00001\/jm050892jb00001_1","doi-asserted-by":"crossref","first-page":"870","DOI":"10.1038\/173870a0","volume":"173","author":"Smith H.","year":"1954","journal-title":"Nature"},{"key":"jm050892jb00002\/jm050892jb00002_1","first-page":"35","volume":"225","author":"Hanna P","year":"1998","journal-title":"Curr. Top. Microbiol. Immunol."},{"key":"jm050892jb00003\/jm050892jb00003_1","doi-asserted-by":"crossref","first-page":"10201","DOI":"10.1073\/pnas.90.21.10198","volume":"90","author":"Hanna P.","year":"1993","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"jm050892jb00004\/jm050892jb00004_1","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1016\/S0165-6147(02)02127-2","volume":"23","author":"Stubbs M. T.","year":"2002","journal-title":"Trends Pharmacol. Sci."},{"key":"jm050892jb00005\/jm050892jb00005_1","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1038\/n35101999","volume":"414","author":"Bradley K. A.","year":"2001","journal-title":"Nature"},{"key":"jm050892jb00006\/jm050892jb00006_1","doi-asserted-by":"crossref","first-page":"838","DOI":"10.1038\/385833a0","volume":"385","author":"Petosa C.","year":"1997","journal-title":"Nature"},{"key":"jm050892jb00007\/jm050892jb00007_1","doi-asserted-by":"crossref","first-page":"5174","DOI":"10.1073\/pnas.0431098100","volume":"100","author":"Scobie H. M.","year":"2003","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"jm050892jb00008\/jm050892jb00008_1","doi-asserted-by":"crossref","first-page":"3166","DOI":"10.1073\/pnas.79.10.3162","volume":"79","author":"Leppla S. H","year":"1982","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"jm050892jb00009\/jm050892jb00009_1","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1006\/bbrc.1998.9040","volume":"248","author":"Vitale G.","year":"1998","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"jm050892jb00010\/jm050892jb00010_1","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1126\/science.280.5364.734","volume":"280","author":"Duesbery N. S.","year":"1998","journal-title":"Science"},{"key":"jm050892jb00011\/jm050892jb00011_1","doi-asserted-by":"crossref","first-page":"2051","DOI":"10.1126\/science.1074340","volume":"297","author":"Park J. M.","year":"2002","journal-title":"Science"},{"key":"jm050892jb00012\/jm050892jb00012_1","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1073\/pnas.0502733102","volume":"102","author":"Forino M.","year":"2005","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"jm050892jb00013\/jm050892jb00013_1","first-page":"8","volume":"5","author":"Wang G.-W.","year":"2004","journal-title":"Arkivoc"},{"key":"jm050892jb00014\/jm050892jb00014_1","first-page":"755","volume":"5","author":"Madkhur H. M. F.","year":"2000","journal-title":"Molecules"},{"key":"jm050892jb00015\/jm050892jb00015_1","first-page":"2680","volume":"10","author":"Madhavan G. R.","year":"2000","journal-title":"Bioorg. Med. Chem."},{"key":"jm050892jb00016\/jm050892jb00016_1","doi-asserted-by":"crossref","first-page":"178","DOI":"10.3390\/50200167","volume":"5","author":"Lacova M.","year":"2000","journal-title":"Molecules"},{"key":"jm050892jb00017\/jm050892jb00017_1","doi-asserted-by":"crossref","first-page":"5967","DOI":"10.1021\/ja00226a005","volume":"110","author":"Cramer R. D.","year":"1988","journal-title":"J. Am. Chem. Soc."},{"key":"jm050892jb00018\/jm050892jb00018_1","doi-asserted-by":"crossref","first-page":"852","DOI":"10.1021\/jm010399h","volume":"45","author":"Buolamwini J. K.","year":"2002","journal-title":"J. Med. Chem."},{"key":"jm050892jb00019\/jm050892jb00019_1","doi-asserted-by":"crossref","first-page":"2178","DOI":"10.1021\/ci049893v","volume":"44","author":"Zhou Z.","year":"2004","journal-title":"J. Chem. Inf. Comput. Sci."},{"key":"jm050892jb00020\/jm050892jb00020_1","doi-asserted-by":"crossref","first-page":"10152","DOI":"10.1073\/pnas.0501980102","volume":"102","author":"Schymkowitz J. W.","year":"2005","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"jm050892jb00021\/jm050892jb00021_1","doi-asserted-by":"crossref","first-page":"748","DOI":"10.1006\/jmbi.1996.0897","volume":"267","author":"Jones G.","year":"1997","journal-title":"J. Mol. Biol."},{"key":"jm050892jb00022\/jm050892jb00022_1","volume-title":"version 6.9","author":"SYBYL"},{"key":"jm050892jb00023\/jm050892jb00023_1","doi-asserted-by":"crossref","first-page":"2309","DOI":"10.1021\/ja955032e","volume":"118","author":"Cornell W. D.","year":"1996","journal-title":"J. Am. Chem. Soc."},{"key":"jm050892jb00024\/jm050892jb00024_1","first-page":"220","volume":"10","author":"Stewart J. J. P","year":"1989","journal-title":"J. Comput. Chem."},{"key":"jm050892jb00025\/jm050892jb00025_1","first-page":"619","volume":"7","author":"Bush B. L.","year":"1993","journal-title":"J. Comput.-Aided Mol. Des."},{"key":"jm050892jb00026\/jm050892jb00026_1","doi-asserted-by":"crossref","first-page":"558","DOI":"10.1107\/S0021889883010985","volume":"16","author":"Connolly M. L","year":"1983","journal-title":"J. Appl. Crystallogr."},{"key":"jm050892jb00027\/jm050892jb00027_1","doi-asserted-by":"crossref","first-page":"4146","DOI":"10.1021\/jm00050a010","volume":"37","author":"Klebe G.","year":"1994","journal-title":"J. Med. Chem."},{"key":"jm050892jb00028\/jm050892jb00028_1","doi-asserted-by":"crossref","first-page":"7963","DOI":"10.1073\/pnas.0502159102","volume":"102","author":"Shoop W. L.","year":"2005","journal-title":"Proc. Natl. Acad. Sci. U.S.A."}],"container-title":["Journal of Medicinal Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/jm050892j","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,8]],"date-time":"2023-04-08T03:47:38Z","timestamp":1680925658000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/jm050892j"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,12,1]]},"references-count":28,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2006,1,1]]}},"alternative-id":["10.1021\/jm050892j"],"URL":"https:\/\/doi.org\/10.1021\/jm050892j","relation":{},"ISSN":["0022-2623","1520-4804"],"issn-type":[{"value":"0022-2623","type":"print"},{"value":"1520-4804","type":"electronic"}],"subject":[],"published":{"date-parts":[[2005,12,1]]}}}