{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,18]],"date-time":"2025-10-18T10:23:04Z","timestamp":1760782984542},"reference-count":22,"publisher":"American Chemical Society (ACS)","issue":"17","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Med. Chem."],"published-print":{"date-parts":[[2007,8,1]]},"DOI":"10.1021\/jm070645a","type":"journal-article","created":{"date-parts":[[2007,8,3]],"date-time":"2007-08-03T12:00:40Z","timestamp":1186142440000},"page":"3980-3983","source":"Crossref","is-referenced-by-count":11,"title":["Targeting Plague Virulence Factors:\u2009 A Combined Machine Learning Method and Multiple Conformational Virtual Screening for the Discovery of <i>Yersinia<\/i> Protein Kinase A Inhibitors"],"prefix":"10.1021","volume":"50","author":[{"given":"Xin","family":"Hu","sequence":"first","affiliation":[{"name":"Laboratory of Structural Microbiology, The Rockefeller University, New York, New York 10021"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gerd","family":"Prehna","sequence":"additional","affiliation":[{"name":"Laboratory of Structural Microbiology, The Rockefeller University, New York, New York 10021"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C. Erec","family":"Stebbins","sequence":"additional","affiliation":[{"name":"Laboratory of Structural Microbiology, The Rockefeller University, New York, New York 10021"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"316","published-online":{"date-parts":[[2007,8,3]]},"reference":[{"key":"jm070645ab00001\/jm070645ab00001_1","doi-asserted-by":"crossref","first-page":"1328","DOI":"10.1126\/science.284.5418.1322","volume":"284","author":"Galan J. E.","year":"1999","journal-title":"Science"},{"key":"jm070645ab00002\/jm070645ab00002_1","doi-asserted-by":"crossref","first-page":"740","DOI":"10.1016\/j.sbi.2004.09.011","volume":"14","author":"Stebbins C. E","year":"2004","journal-title":"Curr. Opin. Struct. Biol."},{"key":"jm070645ab00003\/jm070645ab00003_1","doi-asserted-by":"crossref","first-page":"1282","DOI":"10.1126\/science.283.5406.1279","volume":"283","author":"Henderson D. A","year":"1999","journal-title":"Science"},{"key":"jm070645ab00004\/jm070645ab00004_1","doi-asserted-by":"crossref","first-page":"16","DOI":"10.2165\/00126839-200607010-00001","volume":"7","author":"Marra A","year":"2006","journal-title":"Drugs R&D"},{"key":"jm070645ab00005\/jm070645ab00005_1","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1128\/CMR.10.1.35","volume":"10","author":"Perry R. D.","year":"1997","journal-title":"Clin. Microbiol. Rev."},{"key":"jm070645ab00006\/jm070645ab00006_1","doi-asserted-by":"crossref","first-page":"3233","DOI":"10.1038\/sj.emboj.7601202","volume":"25","author":"Letzelter M.","year":"2006","journal-title":"EMBO J."},{"key":"jm070645ab00007\/jm070645ab00007_1","doi-asserted-by":"crossref","first-page":"9436","DOI":"10.1073\/pnas.170281997","volume":"97","author":"Juris S. J.","year":"2000","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"jm070645ab00008\/jm070645ab00008_1","doi-asserted-by":"crossref","first-page":"880","DOI":"10.1016\/j.cell.2006.06.056","volume":"126","author":"Prehna G.","year":"2006","journal-title":"Cell"},{"key":"jm070645ab00009\/jm070645ab00009_1","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1016\/j.micpath.2006.02.001","volume":"40","author":"Wiley D. J.","year":"2006","journal-title":"Microb. Pathog."},{"key":"jm070645ab00010\/jm070645ab00010_1","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1016\/j.molcel.2007.04.025","volume":"26","author":"Navarro L.","year":"2007","journal-title":"Mol. Cell"},{"key":"jm070645ab00011\/jm070645ab00011_1","doi-asserted-by":"crossref","first-page":"1805","DOI":"10.1126\/science.1095920","volume":"303","author":"Noble M. E.","year":"2004","journal-title":"Science"},{"key":"jm070645ab00012\/jm070645ab00012_1","doi-asserted-by":"crossref","first-page":"1454","DOI":"10.2174\/1389450110607011443","volume":"7","author":"Scapin G","year":"2006","journal-title":"Curr. Drug Targets"},{"key":"jm070645ab00013\/jm070645ab00013_1","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/j.jmb.2004.01.003","volume":"337","author":"Cavasotto C. N.","year":"2004","journal-title":"J. Mol. Biol."},{"key":"jm070645ab00014\/jm070645ab00014_1","doi-asserted-by":"crossref","first-page":"707","DOI":"10.2174\/0929867043455684","volume":"11","author":"Muegge I.","year":"2004","journal-title":"Curr. Med. Chem."},{"key":"jm070645ab00015\/jm070645ab00015_1","doi-asserted-by":"crossref","first-page":"566","DOI":"10.1002\/cbic.200400109","volume":"6","author":"Briem H.","year":"2005","journal-title":"ChemBioChem"},{"key":"jm070645ab00016\/jm070645ab00016_1","first-page":"472","volume":"22","author":"Ford M. G.","year":"2004","journal-title":"J. Mol. Graphics Modell."},{"key":"jm070645ab00017\/jm070645ab00017_1","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1016\/j.molcel.2004.08.024","volume":"15","author":"Nolen B.","year":"2004","journal-title":"Mol. Cell"},{"key":"jm070645ab00018\/jm070645ab00018_1","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1006\/jmbi.2001.4551","volume":"308","author":"Claussen H.","year":"2001","journal-title":"J. Mol. Biol."},{"key":"jm070645ab00019\/jm070645ab00019_1","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1023\/A:1016357811882","volume":"16","author":"Wang R.","year":"2002","journal-title":"J. Comput.-Aided. Mol. Des."},{"key":"jm070645ab00020\/jm070645ab00020_1","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1146\/annurev.pharmtox.42.090601.125940","volume":"42","author":"Hardcastle I. R.","year":"2002","journal-title":"Annu. Rev. Pharmacol. Toxicol."},{"key":"jm070645ab00021\/jm070645ab00021_1","doi-asserted-by":"crossref","first-page":"1836","DOI":"10.1074\/jbc.M209367200","volume":"278","author":"De Moliner E.","year":"2003","journal-title":"J. Biol. Chem."},{"key":"jm070645ab00022\/jm070645ab00022_1","first-page":"1483","volume":"46","author":"McGovern S. L.","year":"2003","journal-title":"J. Med. Chem."}],"container-title":["Journal of Medicinal Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/jm070645a","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,3,24]],"date-time":"2023-03-24T19:25:09Z","timestamp":1679685909000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/jm070645a"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,8,1]]},"references-count":22,"journal-issue":{"issue":"17","published-print":{"date-parts":[[2007,8,1]]}},"alternative-id":["10.1021\/jm070645a"],"URL":"https:\/\/doi.org\/10.1021\/jm070645a","relation":{},"ISSN":["0022-2623","1520-4804"],"issn-type":[{"value":"0022-2623","type":"print"},{"value":"1520-4804","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,8,1]]}}}