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Chem."},{"key":"ref27\/cit27","doi-asserted-by":"crossref","first-page":"1611","DOI":"10.1021\/ja1040896","volume":"133","author":"Frullano L.","year":"2011","journal-title":"J. Am. Chem. Soc."},{"key":"ref28\/cit28","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1002\/cmmi.388","volume":"5","author":"Laurent S.","year":"2010","journal-title":"Contrast Media Mol. Imaging"},{"key":"ref29\/cit29","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1097\/00004424-200102000-00008","volume":"36","author":"Laurent S.","year":"2001","journal-title":"Invest. Radiol."},{"key":"ref30\/cit30","doi-asserted-by":"crossref","first-page":"1625","DOI":"10.1016\/S0016-7037(97)00037-9","volume":"61","author":"Liu X.","year":"1997","journal-title":"Geochim. Cosmochim. Acta"},{"key":"ref31\/cit31","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1002\/cmmi.233","volume":"3","author":"de Sousa Paulo L.","year":"2008","journal-title":"Contrast Media Mol. 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