{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T06:11:08Z","timestamp":1791180668496,"version":"4.1.0"},"reference-count":20,"publisher":"American Chemical Society (ACS)","issue":"13","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Med. Chem."],"published-print":{"date-parts":[[2012,7,12]]},"DOI":"10.1021\/jm300282c","type":"journal-article","created":{"date-parts":[[2012,6,12]],"date-time":"2012-06-12T17:09:26Z","timestamp":1339520966000},"page":"6076-6086","source":"Crossref","is-referenced-by-count":115,"title":["Anticancer Activity and Cellular Repression of c-MYC by the G-Quadruplex-Stabilizing 11-Piperazinylquindoline Is Not Dependent on Direct Targeting of the G-Quadruplex in the c-MYC Promoter"],"prefix":"10.1021","volume":"55","author":[{"given":"Peda V. L.","family":"Boddupally","sequence":"first","affiliation":[{"name":"College of Pharmacy, The University of Arizona, 1703 E. Mabel Street, Tucson,\rArizona 85721, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seongmin","family":"Hahn","sequence":"additional","affiliation":[{"name":"College of Pharmacy, The University of Arizona, 1703 E. Mabel Street, Tucson,\rArizona 85721, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cristina","family":"Beman","sequence":"additional","affiliation":[{"name":"College of Pharmacy, The University of Arizona, 1703 E. Mabel Street, Tucson,\rArizona 85721, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Biswanath","family":"De","sequence":"additional","affiliation":[{"name":"College of Pharmacy, The University of Arizona, 1703 E. Mabel Street, Tucson,\rArizona 85721, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tracy A.","family":"Brooks","sequence":"additional","affiliation":[{"name":"College of Pharmacy, The University of Arizona, 1703 E. Mabel Street, Tucson,\rArizona 85721, United States"},{"name":"BIO5 Institute, The University of Arizona, 1657 E. Helen Street, Tucson,\rArizona 85721, United States"},{"name":"Arizona Cancer Center, The University of Arizona, 1515 N. Campbell Avenue,\rTucson, Arizona 85724, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vijay","family":"Gokhale","sequence":"additional","affiliation":[{"name":"College of Pharmacy, The University of Arizona, 1703 E. Mabel Street, Tucson,\rArizona 85721, United States"},{"name":"BIO5 Institute, The University of Arizona, 1657 E. Helen Street, Tucson,\rArizona 85721, United States"},{"name":"Arizona Cancer Center, The University of Arizona, 1515 N. Campbell Avenue,\rTucson, Arizona 85724, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laurence H.","family":"Hurley","sequence":"additional","affiliation":[{"name":"College of Pharmacy, The University of Arizona, 1703 E. Mabel Street, Tucson,\rArizona 85721, United States"},{"name":"BIO5 Institute, The University of Arizona, 1657 E. Helen Street, Tucson,\rArizona 85721, United States"},{"name":"Arizona Cancer Center, The University of Arizona, 1515 N. Campbell Avenue,\rTucson, Arizona 85724, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2012,6,25]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"crossref","first-page":"2023","DOI":"10.1101\/gad928101","volume":"15","author":"Eisenman R. N.","year":"2001","journal-title":"Genes Dev."},{"key":"ref2\/cit2","doi-asserted-by":"crossref","first-page":"764","DOI":"10.1038\/nrc904","volume":"2","author":"Pelengaris S.","year":"2002","journal-title":"Nat. Rev. Cancer"},{"key":"ref3\/cit3","doi-asserted-by":"crossref","first-page":"3217","DOI":"10.1038\/sj.onc.1207548","volume":"23","author":"Schmidt E. V.","year":"2004","journal-title":"Oncogene"},{"key":"ref4\/cit4","doi-asserted-by":"crossref","first-page":"3004","DOI":"10.1038\/sj.onc.1202746","volume":"18","author":"Nesbit C. E.","year":"1999","journal-title":"Oncogene"},{"key":"ref5\/cit5","doi-asserted-by":"crossref","first-page":"9007","DOI":"10.1038\/sj.onc.1207261","volume":"22","author":"Nilsson J. A.","year":"2003","journal-title":"Oncogene"},{"key":"ref6\/cit6","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1126\/science.6538699","volume":"224","author":"Slamon D. J.","year":"1984","journal-title":"Science"},{"key":"ref7\/cit7","doi-asserted-by":"crossref","first-page":"8702","DOI":"10.1021\/ja040022b","volume":"126","author":"Seenisamy J.","year":"2004","journal-title":"J. Am. Chem. Soc."},{"key":"ref8\/cit8","doi-asserted-by":"crossref","first-page":"11593","DOI":"10.1073\/pnas.182256799","volume":"99","author":"Siddiqui-Jain A.","year":"2002","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"ref9\/cit9","doi-asserted-by":"crossref","first-page":"1055","DOI":"10.1016\/j.biochi.2011.02.013","volume":"93","author":"Chan D.-S.","year":"2011","journal-title":"Biochimie"},{"key":"ref10\/cit10","doi-asserted-by":"crossref","first-page":"1906","DOI":"10.1016\/j.ejmech.2011.02.020","volume":"46","author":"Ma Y.","year":"2011","journal-title":"Eur. J. Med. Chem."},{"key":"ref11\/cit11","doi-asserted-by":"crossref","first-page":"1465","DOI":"10.1021\/jm0610088","volume":"50","author":"Ou T. M.","year":"2007","journal-title":"J. Med. Chem."},{"key":"ref12\/cit12","doi-asserted-by":"crossref","first-page":"8235","DOI":"10.1016\/j.bmc.2010.10.021","volume":"18","author":"Peng D.","year":"2010","journal-title":"Bioorg. Med. Chem."},{"key":"ref13\/cit13","doi-asserted-by":"crossref","first-page":"981","DOI":"10.1039\/b316055f","volume":"2","author":"Guyen B.","year":"2004","journal-title":"Org. Biomol. Chem."},{"key":"ref14\/cit14","doi-asserted-by":"crossref","first-page":"41018","DOI":"10.1074\/jbc.M111.274720","volume":"286","author":"Brown R. V.","year":"2011","journal-title":"J. Biol. Chem."},{"key":"ref15\/cit15","first-page":"8.3.1","volume-title":"Current Protocols in Nucleic Acid Chemistry","volume":"1","author":"Chaires J. B.","year":"2003"},{"key":"ref16\/cit16","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1289\/ehp.8353155","volume":"53","author":"Mossman B. T.","year":"1983","journal-title":"Environ. Health Perspect."},{"key":"ref17\/cit17","doi-asserted-by":"crossref","first-page":"2754","DOI":"10.1021\/jm970735n","volume":"41","author":"Bierer D. E.","year":"1998","journal-title":"J. Med. Chem."},{"key":"ref18\/cit18","doi-asserted-by":"crossref","first-page":"2096","DOI":"10.1248\/cpb.45.2096","volume":"45","author":"Takeuchi Y.","year":"1997","journal-title":"Chem. Pharm. Bull. (Tokyo)"},{"key":"ref19\/cit19","doi-asserted-by":"crossref","first-page":"3055","DOI":"10.1039\/b806042h","author":"Dash J.","year":"2008","journal-title":"Chem. Commun. (Cambridge, U. K.)"},{"key":"ref20\/cit20","doi-asserted-by":"crossref","first-page":"3434","DOI":"10.1016\/j.bmcl.2009.05.025","volume":"19","author":"El Bakali J.","year":"2009","journal-title":"Bioorg. Med. Chem. Lett."}],"container-title":["Journal of Medicinal Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/jm300282c","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,3]],"date-time":"2023-04-03T03:48:19Z","timestamp":1680493699000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/jm300282c"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,6,25]]},"references-count":20,"journal-issue":{"issue":"13","published-print":{"date-parts":[[2012,7,12]]}},"alternative-id":["10.1021\/jm300282c"],"URL":"https:\/\/doi.org\/10.1021\/jm300282c","relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.717948805.793453906","asserted-by":"object"}]},"ISSN":["0022-2623","1520-4804"],"issn-type":[{"value":"0022-2623","type":"print"},{"value":"1520-4804","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,6,25]]}}}