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Res."},{"key":"ref49\/cit49","doi-asserted-by":"crossref","first-page":"e43313","DOI":"10.1371\/journal.pone.0043313","volume":"7","author":"Zgheib C.","year":"2012","journal-title":"PLoS One"},{"key":"ref50\/cit50","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1021\/tx900034r","volume":"22","author":"Callan H. E.","year":"2009","journal-title":"Chem. Res. Toxicol."},{"key":"ref51\/cit51","doi-asserted-by":"crossref","first-page":"2129","DOI":"10.1016\/0006-2952(93)90026-S","volume":"45","author":"Nagasawa H. T.","year":"1993","journal-title":"Biochem. Pharmacol."},{"key":"ref52\/cit52","doi-asserted-by":"crossref","first-page":"1274","DOI":"10.1016\/j.freeradbiomed.2011.02.008","volume":"50","author":"Cline M. R.","year":"2011","journal-title":"Free Radical Biol. Med."},{"key":"ref53\/cit53","doi-asserted-by":"crossref","first-page":"13349","DOI":"10.1021\/bi9713658","volume":"36","author":"Ellis H. 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