{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T15:21:10Z","timestamp":1789917670187,"version":"4.0.1"},"reference-count":81,"publisher":"American Chemical Society (ACS)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Med. Chem."],"published-print":{"date-parts":[[2013,2,28]]},"DOI":"10.1021\/jm4000616","type":"journal-article","created":{"date-parts":[[2013,2,7]],"date-time":"2013-02-07T18:19:20Z","timestamp":1360261160000},"page":"1761-1771","source":"Crossref","is-referenced-by-count":101,"title":["Cloning, Characterization, and Sulfonamide and Thiol Inhibition Studies of an \u03b1-Carbonic Anhydrase from <i>Trypanosoma cruzi<\/i>, the Causative Agent of Chagas Disease"],"prefix":"10.1021","volume":"56","author":[{"given":"Peiwen","family":"Pan","sequence":"first","affiliation":[{"name":"Institute of Biomedical Technology,\rFimlab Ltd., School of Medicine and BioMediTech, University of Tampere and Tampere University Hospital, Medisiinarinkatu\r3, 33520 Tampere, Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alane Beatriz","family":"Vermelho","sequence":"additional","affiliation":[{"name":"Laborat\u00f3rio Proteases\rde Microrganismos, Instituto de Microbiologia Paulo de G\u00f3es, Universidade Federal do Rio de Janeiro, UFRJ, CCS,\rBloco I, Sala 32, Cidade Universit\u00e1ria, Av. Carlos Chagas Filho,\r373, Ilha do Fund\u00e3o, Rio de Janeiro R.J., Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giseli","family":"Capaci Rodrigues","sequence":"additional","affiliation":[{"name":"Laborat\u00f3rio Proteases\rde Microrganismos, Instituto de Microbiologia Paulo de G\u00f3es, Universidade Federal do Rio de Janeiro, UFRJ, CCS,\rBloco I, Sala 32, Cidade Universit\u00e1ria, Av. Carlos Chagas Filho,\r373, Ilha do Fund\u00e3o, Rio de Janeiro R.J., Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Scozzafava","sequence":"additional","affiliation":[{"name":"Laboratorio di Chimica Bioinorganica,\rRm. 188, Polo Scientifico, Universit\u00e0 degli Studi di Firenze, Via della Lastruccia 3, 50019 Sesto Fiorentino,\rFlorence, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martti E. E.","family":"Tolvanen","sequence":"additional","affiliation":[{"name":"Institute of Biomedical Technology,\rFimlab Ltd., School of Medicine and BioMediTech, University of Tampere and Tampere University Hospital, Medisiinarinkatu\r3, 33520 Tampere, Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seppo","family":"Parkkila","sequence":"additional","affiliation":[{"name":"Institute of Biomedical Technology,\rFimlab Ltd., School of Medicine and BioMediTech, University of Tampere and Tampere University Hospital, Medisiinarinkatu\r3, 33520 Tampere, Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clemente","family":"Capasso","sequence":"additional","affiliation":[{"name":"Istituto di Biochimica delle Proteine, CNR, Via P. Castellino 111, 80131 Napoli,\rItaly"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudiu T.","family":"Supuran","sequence":"additional","affiliation":[{"name":"Laboratorio di Chimica Bioinorganica,\rRm. 188, Polo Scientifico, Universit\u00e0 degli Studi di Firenze, Via della Lastruccia 3, 50019 Sesto Fiorentino,\rFlorence, Italy"},{"name":"Dipartimento di Scienze\rFarmaceutiche, Universit\u00e0 degli Studi di Firenze, Via Ugo Schiff\r6, 50019 Sesto Fiorentino, Florence, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2013,2,19]]},"reference":[{"key":"ref1\/cit1a","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1590\/S0037-86822012000300002","volume":"45","author":"Coura J. R.","year":"2012","journal-title":"Rev. Soc. Bras. Med. Trop."},{"key":"ref1\/cit1b","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1016\/j.idc.2012.03.002","volume":"26","author":"Rassi A.","year":"2012","journal-title":"Infect. Dis. Clin. North Am."},{"key":"ref2\/cit2a","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1111\/j.1365-4632.2011.05380.x","volume":"51","author":"Hemmige V.","year":"2012","journal-title":"Int. J. Dermatol."},{"key":"ref2\/cit2b","doi-asserted-by":"crossref","first-page":"734","DOI":"10.1111\/j.1574-6976.2012.00333.x","volume":"36","author":"Fernandes M. C.","year":"2012","journal-title":"FEMS Microbiol. Rev."},{"key":"ref3\/cit3a","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1016\/j.pt.2006.09.011","volume":"22","author":"Schofield C. J.","year":"2006","journal-title":"Trends Parasitol."},{"key":"ref3\/cit3b","doi-asserted-by":"crossref","first-page":"361","DOI":"10.3389\/fimmu.2012.00361","volume":"3","author":"Maeda F. Y.","year":"2012","journal-title":"Front. Immunol."},{"key":"ref4\/cit4","doi-asserted-by":"crossref","first-page":"1390","DOI":"10.1016\/j.micinf.2012.09.003","volume":"14","author":"Osorio L.","year":"2012","journal-title":"Microbes Infect."},{"key":"ref5\/cit5","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1590\/S1415-47572012005000008","volume":"35","author":"Teixeira S. M.","year":"2012","journal-title":"Genet. Mol. Biol."},{"key":"ref6\/cit6","first-page":"1","volume":"25","author":"S\u00e1nchez L. V.","year":"2012","journal-title":"Parasitology"},{"key":"ref7\/cit7a","doi-asserted-by":"crossref","first-page":"888","DOI":"10.1002\/jps.23010","volume":"101","author":"Salomon C. J.","year":"2012","journal-title":"J. Pharm. Sci."},{"key":"ref7\/cit7b","doi-asserted-by":"crossref","first-page":"1057","DOI":"10.1111\/j.1365-3156.2012.03025.x","volume":"17","author":"Matta Guedes P. M.","year":"2012","journal-title":"Trop. Med. Int. Health"},{"key":"ref8\/cit8a","doi-asserted-by":"crossref","first-page":"1355","DOI":"10.2174\/138955708786369528","volume":"8","author":"Cerecetto H.","year":"2008","journal-title":"Mini-Rev. Med. Chem."},{"key":"ref8\/cit8b","doi-asserted-by":"publisher","DOI":"10.3109\/14756366.2012.700928"},{"key":"ref9\/cit9","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1038\/35020000","volume":"406","author":"Heidelberg J. F.","year":"2000","journal-title":"Nature"},{"key":"ref10\/cit10a","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1073\/pnas.221575398","volume":"99","author":"DelVecchio V. G.","year":"2002","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"ref10\/cit10b","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1038\/41483","volume":"388","author":"Tomb J. F.","year":"1997","journal-title":"Nature"},{"key":"ref11\/cit11","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1038\/31159","volume":"393","author":"Cole S. T.","year":"1998","journal-title":"Nature"},{"key":"ref12\/cit12a","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1038\/nrd2467","volume":"7","author":"Supuran C. T.","year":"2008","journal-title":"Nat. Rev. Drug Discovery"},{"key":"ref12\/cit12b","doi-asserted-by":"crossref","first-page":"3467","DOI":"10.1016\/j.bmcl.2010.05.009","volume":"20","author":"Supuran C. T.","year":"2010","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"ref12\/cit12c","doi-asserted-by":"crossref","first-page":"759","DOI":"10.3109\/14756366.2012.672983","volume":"27","author":"Supuran C. T.","year":"2012","journal-title":"J. Enzyme Inhib. Med. Chem."},{"key":"ref13\/cit13a","doi-asserted-by":"crossref","first-page":"34","DOI":"10.3389\/fphar.2011.00034","volume":"2","author":"Supuran C. T.","year":"2011","journal-title":"Front. Pharmacol."},{"key":"ref13\/cit13b","doi-asserted-by":"crossref","first-page":"1165","DOI":"10.4155\/fmc.11.69","volume":"3","author":"Supuran C. T.","year":"2011","journal-title":"Future Med. Chem."},{"key":"ref14\/cit14a","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1080\/14756360410001689540","volume":"19","author":"Pastorekova S.","year":"2004","journal-title":"J. Enzyme Inhib. Med. Chem."},{"key":"ref14\/cit14b","doi-asserted-by":"crossref","first-page":"4421","DOI":"10.1021\/cr200176r","volume":"112","author":"Alterio V.","year":"2012","journal-title":"Chem. Rev."},{"key":"ref15\/cit15a","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1038\/nrd3554","volume":"10","author":"Neri D.","year":"2011","journal-title":"Nat. Rev. Drug Discovery"},{"key":"ref15\/cit15b","doi-asserted-by":"crossref","first-page":"16233","DOI":"10.1073\/pnas.0908301106","volume":"106","author":"Alterio V.","year":"2009","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"ref16\/cit16a","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1002\/med.10025","volume":"23","author":"Supuran C. T.","year":"2003","journal-title":"Med. Res. Rev."},{"key":"ref16\/cit16b","doi-asserted-by":"crossref","first-page":"4884","DOI":"10.1021\/jm001051+","volume":"43","author":"Casini A.","year":"2000","journal-title":"J. Med. Chem."},{"key":"ref17\/cit17a","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1111\/j.1574-6976.2000.tb00546.x","volume":"24","author":"Smith K. S.","year":"2000","journal-title":"FEMS Microbiol. Rev."},{"key":"ref17\/cit17b","doi-asserted-by":"crossref","first-page":"392","DOI":"10.3109\/14756366.2011.650168","volume":"28","author":"Maresca A.","year":"2013","journal-title":"J. Enzyme Inhib. Med. Chem."},{"key":"ref18\/cit18a","doi-asserted-by":"crossref","first-page":"1172","DOI":"10.1016\/j.bmc.2010.12.048","volume":"19","author":"Joseph P.","year":"2011","journal-title":"Bioorg. Med. Chem."},{"key":"ref18\/cit18b","doi-asserted-by":"crossref","first-page":"2277","DOI":"10.1021\/jm901855h","volume":"53","author":"Joseph P.","year":"2010","journal-title":"J. Med. Chem."},{"key":"ref19\/cit19a","doi-asserted-by":"crossref","first-page":"18782","DOI":"10.1074\/jbc.M414348200","volume":"280","author":"Suarez Covarrubias A.","year":"2005","journal-title":"J. Biol. Chem."},{"key":"ref19\/cit19b","doi-asserted-by":"crossref","first-page":"3116","DOI":"10.1021\/jm9003126","volume":"52","author":"Nishimori I.","year":"2009","journal-title":"J. Med. Chem."},{"key":"ref19\/cit19c","doi-asserted-by":"crossref","first-page":"4063","DOI":"10.1021\/jm9004016","volume":"52","author":"G\u00fczel \u00d6.","year":"2009","journal-title":"J. Med. Chem."},{"key":"ref19\/cit19d","doi-asserted-by":"crossref","first-page":"6649","DOI":"10.1016\/j.bmcl.2009.10.009","volume":"19","author":"Carta F.","year":"2009","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"ref20\/cit20a","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1016\/j.bmc.2010.11.031","volume":"19","author":"Burghout P.","year":"2011","journal-title":"Bioorg. Med. Chem."},{"key":"ref20\/cit20b","doi-asserted-by":"crossref","first-page":"3233","DOI":"10.2174\/138161210793429797","volume":"16","author":"Supuran C. T.","year":"2010","journal-title":"Curr. Pharm. Des."},{"key":"ref20\/cit20c","doi-asserted-by":"crossref","first-page":"3591","DOI":"10.1016\/j.bmcl.2011.04.105","volume":"21","author":"Vullo D.","year":"2011","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"ref20\/cit20d","doi-asserted-by":"crossref","first-page":"407","DOI":"10.3109\/14756366.2011.641015","volume":"28","author":"Maresca A.","year":"2013","journal-title":"J. Enzyme Inhib. Med. Chem."},{"key":"ref21\/cit21a","doi-asserted-by":"crossref","first-page":"10742","DOI":"10.1021\/jm301611m","volume":"55","author":"Del Prete S.","year":"2012","journal-title":"J. Med. Chem."},{"key":"ref21\/cit21b","doi-asserted-by":"crossref","first-page":"2117","DOI":"10.1021\/jm0512600","volume":"49","author":"Nishimori I.","year":"2006","journal-title":"J. Med. Chem."},{"key":"ref21\/cit21c","doi-asserted-by":"crossref","first-page":"622","DOI":"10.2174\/138161208783877875","volume":"14","author":"Nishimori I.","year":"2008","journal-title":"Curr. Pharm. Des."},{"key":"ref21\/cit21d","doi-asserted-by":"crossref","first-page":"3585","DOI":"10.1016\/j.bmcl.2007.04.063","volume":"17","author":"Nishimori I.","year":"2007","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"ref21\/cit21e","doi-asserted-by":"crossref","first-page":"384","DOI":"10.3109\/14756366.2011.645539","volume":"28","author":"Maresca A.","year":"2013","journal-title":"J. Enzyme Inhib. Med. Chem."},{"key":"ref21\/cit21f","doi-asserted-by":"crossref","first-page":"388","DOI":"10.3109\/14756366.2011.649268","volume":"28","author":"Maresca A.","year":"2013","journal-title":"J. Enzyme Inhib. Med. Chem."},{"key":"ref22\/cit22a","doi-asserted-by":"crossref","first-page":"2021","DOI":"10.1016\/j.cub.2005.10.040","volume":"15","author":"Klengel T.","year":"2005","journal-title":"Curr. Biol."},{"key":"ref22\/cit22b","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1128\/EC.5.1.103-111.2006","volume":"5","author":"Mogensen E. G.","year":"2006","journal-title":"Eukaryotic Cell"},{"key":"ref22\/cit22c","doi-asserted-by":"crossref","first-page":"1207","DOI":"10.1016\/j.jmb.2008.11.037","volume":"385","author":"Schlicker C.","year":"2009","journal-title":"J. Mol. Biol."},{"key":"ref23\/cit23a","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1016\/j.bmc.2004.10.015","volume":"13","author":"Krungkrai J.","year":"2005","journal-title":"Bioorg. Med. Chem."},{"key":"ref23\/cit23b","doi-asserted-by":"crossref","first-page":"909","DOI":"10.2174\/156802607780636744","volume":"7","author":"Krungkrai J.","year":"2007","journal-title":"Curr. Top. Med. Chem."},{"key":"ref23\/cit23c","doi-asserted-by":"crossref","first-page":"631","DOI":"10.2174\/138161208783877901","volume":"14","author":"Krungkrai J.","year":"2008","journal-title":"Curr. Pharm. Des."},{"key":"ref23\/cit23d","doi-asserted-by":"crossref","first-page":"5466","DOI":"10.1016\/j.bmcl.2008.09.030","volume":"18","author":"Krungkrai J.","year":"2008","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"ref24\/cit24","doi-asserted-by":"crossref","first-page":"27799","DOI":"10.1074\/jbc.M800938200","volume":"283","author":"Hilvo M.","year":"2008","journal-title":"J. Biol. Chem."},{"key":"ref25\/cit25a","doi-asserted-by":"crossref","first-page":"2561","DOI":"10.1016\/S0021-9258(18)62326-9","volume":"246","author":"Khalifah R. G.","year":"1971","journal-title":"J. Biol. Chem."},{"key":"ref25\/cit25b","doi-asserted-by":"crossref","first-page":"14726","DOI":"10.1021\/ja3068098","volume":"134","author":"Fisher S. Z.","year":"2012","journal-title":"J. Am. Chem. Soc."},{"key":"ref25\/cit25c","doi-asserted-by":"crossref","first-page":"1322","DOI":"10.1021\/bi802035f","volume":"48","author":"Genis C.","year":"2009","journal-title":"Biochemistry"},{"key":"ref25\/cit25d","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1021\/bi301099k","volume":"52","author":"Mikulski R.","year":"2013","journal-title":"Biochemistry"},{"key":"ref25\/cit25e","doi-asserted-by":"crossref","first-page":"1403","DOI":"10.1016\/j.bmc.2012.01.007","volume":"20","author":"Ohradanova A.","year":"2012","journal-title":"Bioorg. Med. Chem."},{"key":"ref26\/cit26a","doi-asserted-by":"crossref","first-page":"7142","DOI":"10.1016\/j.bmcl.2012.09.065","volume":"22","author":"Vullo D.","year":"2012","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"ref26\/cit26b","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmc.2012.09.047"},{"key":"ref26\/cit26c","doi-asserted-by":"crossref","first-page":"892","DOI":"10.3109\/14756366.2012.703185","volume":"27","author":"Capasso C.","year":"2012","journal-title":"J. Enzyme Inhib. Med. Chem."},{"key":"ref27\/cit27","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1517\/13543776.2012.698264","volume":"22","author":"Carta F.","year":"2012","journal-title":"Expert Opin. Ther. Pat."},{"key":"ref28\/cit28","doi-asserted-by":"crossref","first-page":"6975","DOI":"10.1016\/j.bmc.2007.07.044","volume":"15","author":"Abdel-Hamid M. K.","year":"2007","journal-title":"Bioorg. Med. Chem."},{"key":"ref29\/cit29a","doi-asserted-by":"crossref","first-page":"1868","DOI":"10.1039\/c2cc16395k","volume":"48","author":"Carta F.","year":"2012","journal-title":"Chem. Commun. (Cambridge, U. K.)"},{"key":"ref29\/cit29b","doi-asserted-by":"crossref","first-page":"895","DOI":"10.3109\/14756366.2011.554415","volume":"26","author":"Kolayli S.","year":"2011","journal-title":"J. Enzyme Inhib. Med. Chem."},{"key":"ref29\/cit29c","doi-asserted-by":"crossref","first-page":"407","DOI":"10.3109\/14756366.2011.641015","volume":"28","author":"Maresca A.","year":"2013","journal-title":"J. Enzyme Inhib. Med. Chem."},{"key":"ref29\/cit29d","doi-asserted-by":"crossref","first-page":"1721","DOI":"10.1021\/jm300031j","volume":"55","author":"Carta F.","year":"2012","journal-title":"J. Med. Chem."},{"key":"ref30\/cit30a","doi-asserted-by":"crossref","first-page":"3057","DOI":"10.1021\/ja809683v","volume":"131","author":"Maresca A.","year":"2009","journal-title":"J. Am. Chem. Soc."},{"key":"ref30\/cit30b","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1021\/jm901287j","volume":"53","author":"Maresca A.","year":"2010","journal-title":"J. Med. Chem."},{"key":"ref30\/cit30c","doi-asserted-by":"crossref","first-page":"4511","DOI":"10.1016\/j.bmcl.2010.06.040","volume":"20","author":"Maresca A.","year":"2010","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"ref31\/cit31","doi-asserted-by":"crossref","first-page":"5511","DOI":"10.1021\/jm1003667","volume":"53","author":"Carta F.","year":"2010","journal-title":"J. Med. Chem."},{"key":"ref32\/cit32","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1111\/j.1747-0285.2009.00857.x","volume":"74","author":"De Simone G.","year":"2009","journal-title":"Chem. Biol. Drug Des."},{"key":"ref33\/cit33a","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1517\/13543776.14.5.667","volume":"14","author":"Scozzafava A.","year":"2004","journal-title":"Expert Opin. Ther. Pat."},{"key":"ref33\/cit33b","doi-asserted-by":"crossref","first-page":"67","DOI":"10.4324\/9780203475300","volume-title":"Carbonic Anhydrase: Its Inhibitors and Activators","author":"Supuran C. T.","year":"2004"},{"key":"ref33\/cit33c","doi-asserted-by":"crossref","first-page":"886","DOI":"10.3109\/14756366.2011.638921","volume":"27","author":"Liu F.","year":"2012","journal-title":"J. Enzyme Inhib. Med. Chem."},{"key":"ref33\/cit33d","doi-asserted-by":"crossref","first-page":"749","DOI":"10.3109\/14756366.2011.570759","volume":"26","author":"Ozensoy O.","year":"2011","journal-title":"J. Enzyme Inhib. Med. Chem."},{"key":"ref33\/cit33e","doi-asserted-by":"crossref","first-page":"862","DOI":"10.3109\/14756366.2011.588227","volume":"26","author":"Bootorabi F.","year":"2011","journal-title":"J. Enzyme Inhib. Med. Chem."},{"key":"ref34\/cit34","doi-asserted-by":"crossref","first-page":"3174","DOI":"10.1021\/bi702385k","volume":"47","author":"Barrese A. A.","year":"2008","journal-title":"Biochemistry"},{"key":"ref35\/cit35","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1002\/9781118098141.ch23","volume-title":"Polypharmacology in Drug Discovery","author":"Supuran C. T.","year":"2012"},{"key":"ref36\/cit36","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1007\/s00436-006-0126-y","volume":"99","author":"Rolon M.","year":"2006","journal-title":"Parasitol. Res."}],"container-title":["Journal of Medicinal Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/jm4000616","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,15]],"date-time":"2023-04-15T05:32:05Z","timestamp":1681536725000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/jm4000616"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,2,19]]},"references-count":81,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2013,2,28]]}},"alternative-id":["10.1021\/jm4000616"],"URL":"https:\/\/doi.org\/10.1021\/jm4000616","relation":{},"ISSN":["0022-2623","1520-4804"],"issn-type":[{"value":"0022-2623","type":"print"},{"value":"1520-4804","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,2,19]]}}}