{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T04:36:50Z","timestamp":1791175010037,"version":"4.1.0"},"reference-count":245,"publisher":"American Chemical Society (ACS)","issue":"11","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Med. Chem."],"published-print":{"date-parts":[[2010,6,10]]},"DOI":"10.1021\/jm901024b","type":"journal-article","created":{"date-parts":[[2010,1,26]],"date-time":"2010-01-26T14:10:26Z","timestamp":1264515026000},"page":"4305-4331","source":"Crossref","is-referenced-by-count":35,"title":["Current and Future Medical Approaches To Combat the Anthrax Threat"],"prefix":"10.1021","volume":"53","author":[{"given":"Dimitrios G.","family":"Bouzianas","sequence":"first","affiliation":[{"name":"Laboratory of Molecular Endocrinology, Division of Endocrinology and Metabolism, AHEPA University Hospital, 1 S. Kyriakidi Street, P.C. 54636, Thessaloniki, Macedonia, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2010,1,26]]},"reference":[{"issue":"8","key":"ref1\/cit1","doi-asserted-by":"crossref","first-page":"667","DOI":"10.7326\/0003-4819-142-8-200504190-00016","volume":"142","author":"Webb G. F.","year":"2005","journal-title":"Ann. Intern. Med."},{"issue":"17","key":"ref2\/cit2","doi-asserted-by":"crossref","first-page":"2236","DOI":"10.1001\/jama.287.17.2236","volume":"287","author":"Inglesby T. V.","year":"2002","journal-title":"JAMA, J. Am. Med. Assoc."},{"key":"ref3\/cit3","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1016\/S0076-6879(07)38025-7","volume":"438","author":"Bromberg-White J. L.","year":"2008","journal-title":"Methods Enzymol."},{"issue":"5","key":"ref4\/cit4","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1002\/pds.1547","volume":"17","author":"Meropol S. B.","year":"2008","journal-title":"Pharmacoepidemiol. Drug Saf."},{"issue":"9","key":"ref5\/cit5","doi-asserted-by":"crossref","first-page":"1266","DOI":"10.1016\/j.addr.2005.01.028","volume":"57","author":"Brey R. N.","year":"2005","journal-title":"Adv. Drug Delivery Rev."},{"issue":"8","key":"ref6\/cit6","doi-asserted-by":"crossref","first-page":"1584","DOI":"10.1002\/elps.200500747","volume":"27","author":"Kuhn J. F.","year":"2006","journal-title":"Electrophoresis"},{"issue":"3","key":"ref7\/cit7","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1080\/08998280.2005.11928074","volume":"18","author":"Riedel S.","year":"2005","journal-title":"Baylor Univ. Med. Cent. Proc."},{"issue":"1","key":"ref8\/cit8","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1086\/523578","volume":"46","author":"Grabenstein J. D.","year":"2008","journal-title":"Clin. Infect. Dis."},{"issue":"1","key":"ref9\/cit9","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1186\/1476-9433-4-4","volume":"4","author":"Wang J. Y.","year":"2005","journal-title":"Med. Immunol."},{"key":"ref10\/cit10","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1586\/14787210.5.4.665","volume":"5","author":"Bouzianas D. G.","year":"2007","journal-title":"Expert Rev. Anti-Infect. Ther."},{"key":"ref11\/cit11","first-page":"409","volume":"5","author":"Lew D.","year":"2003","journal-title":"Curr. Treat. Treat. Options Infect. Dis."},{"issue":"1","key":"ref12\/cit12","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1038\/nrmicro1818","volume":"6","author":"Cegelski L.","year":"2008","journal-title":"Nat. Rev. Microbiol."},{"key":"ref13\/cit13","doi-asserted-by":"crossref","first-page":"1202","DOI":"10.1126\/science.7973702","volume":"266","author":"Meselson M.","year":"1994","journal-title":"Science"},{"issue":"3","key":"ref14\/cit14","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1136\/jcp.56.3.182","volume":"56","author":"Spencer R. C.","year":"2003","journal-title":"J. Clin. Pathol."},{"issue":"1","key":"ref15\/cit15","doi-asserted-by":"crossref","first-page":"67","DOI":"10.3390\/ijerph2006030008","volume":"3","author":"Bennett R. L.","year":"2006","journal-title":"Int. J. Environ. Res. Public Health"},{"issue":"11","key":"ref16\/cit16","doi-asserted-by":"crossref","first-page":"1945","DOI":"10.2105\/AJPH.2006.102749","volume":"97","author":"Weiss M. M.","year":"2007","journal-title":"Am. J. Public Health"},{"issue":"4","key":"ref17\/cit17","doi-asserted-by":"crossref","first-page":"924","DOI":"10.1111\/j.1462-5822.2006.00840.x","volume":"9","author":"Rossi Paccani S.","year":"2007","journal-title":"Cell. Microbiol."},{"issue":"3","key":"ref18\/cit18","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1042\/BJ20061891","volume":"402","author":"Turk B. E.","year":"2007","journal-title":"Biochem. J."},{"issue":"9","key":"ref19\/cit19","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1016\/j.it.2006.07.002","volume":"27","author":"Baldari C. T.","year":"2006","journal-title":"Trends Immunol."},{"issue":"7","key":"ref20\/cit20","doi-asserted-by":"crossref","first-page":"3434","DOI":"10.1128\/IAI.01345-06","volume":"75","author":"Bergman N. H.","year":"2007","journal-title":"Infect. Immun."},{"issue":"6","key":"ref21\/cit21","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1517\/14712598.7.6.843","volume":"7","author":"Li Y.","year":"2007","journal-title":"Expert Opin. Biol. Ther."},{"issue":"30","key":"ref22\/cit22","doi-asserted-by":"crossref","first-page":"30945","DOI":"10.1074\/jbc.M401613200","volume":"279","author":"Daubenspeck J. M.","year":"2004","journal-title":"J. Biol. Chem."},{"key":"ref23\/cit23","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1146\/annurev.biochem.75.103004.142728","volume":"76","author":"Young J. A.","year":"2007","journal-title":"Annu. Rev. Biochem."},{"issue":"6860","key":"ref24\/cit24","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1038\/n35101998","volume":"414","author":"Pannifer A. D.","year":"2001","journal-title":"Nature"},{"issue":"10","key":"ref25\/cit25","doi-asserted-by":"crossref","first-page":"3162","DOI":"10.1073\/pnas.79.10.3162","volume":"79","author":"Leppla S. H.","year":"1982","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"issue":"6870","key":"ref26\/cit26","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1038\/415396a","volume":"415","author":"Drum C. L.","year":"2002","journal-title":"Nature"},{"issue":"22","key":"ref27\/cit27","doi-asserted-by":"crossref","first-page":"7765","DOI":"10.1128\/JB.187.22.7765-7772.2005","volume":"187","author":"Candela T.","year":"2005","journal-title":"J. Bacteriol."},{"key":"ref28\/cit28","doi-asserted-by":"crossref","first-page":"397","DOI":"10.2217\/17460913.1.4.397","volume":"1","author":"Passalacqua K. D.","year":"2006","journal-title":"Future Microbiol."},{"issue":"10","key":"ref29\/cit29","doi-asserted-by":"crossref","first-page":"4754","DOI":"10.1128\/IAI.00575-07","volume":"75","author":"Glomski I. J.","year":"2007","journal-title":"Infect. Immun."},{"issue":"2","key":"ref30\/cit30","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1128\/IAI.00764-08","volume":"77","author":"Ezzell J. W.","year":"2009","journal-title":"Infect. Immun."},{"key":"ref31\/cit31","first-page":"3","volume":"4","author":"Bakhteeva I. V.","year":"2005","journal-title":"Mol. Gen. Mikrobiol. Virusol."},{"key":"ref32\/cit32","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1038\/n35101999","volume":"414","author":"Bradley K. A.","year":"2001","journal-title":"Nature"},{"issue":"7002","key":"ref33\/cit33","doi-asserted-by":"crossref","first-page":"905","DOI":"10.1038\/nature02763","volume":"430","author":"Santelli E.","year":"2004","journal-title":"Nature"},{"issue":"3","key":"ref34\/cit34","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1164\/rccm.200608-1239CP","volume":"175","author":"Sherer K.","year":"2007","journal-title":"Am. J. Respir. Crit. Care Med."},{"key":"ref35\/cit35","doi-asserted-by":"crossref","first-page":"1871","DOI":"10.1016\/S0002-9440(10)62496-0","volume":"166","author":"Warfel J. M.","year":"2005","journal-title":"Am. J. Pathol."},{"issue":"8","key":"ref36\/cit36","doi-asserted-by":"crossref","first-page":"4430","DOI":"10.1128\/IAI.00446-06","volume":"74","author":"Chakrabarty K.","year":"2006","journal-title":"Infect. Immun."},{"issue":"8","key":"ref37\/cit37","doi-asserted-by":"crossref","first-page":"3729","DOI":"10.1128\/IAI.00046-07","volume":"75","author":"Chakrabarty K.","year":"2007","journal-title":"Infect. Immun."},{"issue":"12","key":"ref38\/cit38","doi-asserted-by":"crossref","first-page":"7994","DOI":"10.4049\/jimmunol.178.12.7994","volume":"178","author":"Cleret A.","year":"2007","journal-title":"J. Immunol."},{"issue":"4","key":"ref39\/cit39","doi-asserted-by":"crossref","first-page":"572","DOI":"10.1086\/510856","volume":"195","author":"Cui X.","year":"2007","journal-title":"J. Infect. Dis."},{"issue":"5","key":"ref40\/cit40","doi-asserted-by":"crossref","first-page":"2120","DOI":"10.1128\/IAI.01781-06","volume":"75","author":"Firoved A. M.","year":"2007","journal-title":"Infect. Immun."},{"issue":"1","key":"ref41\/cit41","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1128\/IAI.00633-08","volume":"77","author":"Loving C. L.","year":"2009","journal-title":"Infect. Immun."},{"issue":"10","key":"ref42\/cit42","doi-asserted-by":"crossref","first-page":"6155","DOI":"10.4049\/jimmunol.176.10.6155","volume":"176","author":"Fang H.","year":"2006","journal-title":"J. Immunol."},{"issue":"12","key":"ref43\/cit43","doi-asserted-by":"crossref","first-page":"8275","DOI":"10.1128\/IAI.73.12.8275-8281.2005","volume":"73","author":"Comer J. E.","year":"2005","journal-title":"Infect. Immun."},{"issue":"9","key":"ref44\/cit44","doi-asserted-by":"crossref","first-page":"2240","DOI":"10.1038\/sj.emboj.7601687","volume":"26","author":"During R. L.","year":"2007","journal-title":"EMBO J."},{"issue":"3","key":"ref45\/cit45","doi-asserted-by":"crossref","first-page":"1262","DOI":"10.1128\/IAI.01032-08","volume":"77","author":"Nour A. M.","year":"2009","journal-title":"Infect. Immun."},{"issue":"1","key":"ref46\/cit46","doi-asserted-by":"crossref","first-page":"e736","DOI":"10.1371\/journal.pone.0000736","volume":"2","author":"Gold J. A.","year":"2007","journal-title":"PLoS One"},{"issue":"3","key":"ref47\/cit47","doi-asserted-by":"crossref","first-page":"594","DOI":"10.1111\/j.1365-2672.2006.03112.x","volume":"101","author":"Baillie L. W.","year":"2006","journal-title":"J. Appl. Microbiol."},{"key":"ref48\/cit48","doi-asserted-by":"crossref","first-page":"2335","DOI":"10.2741\/3382","volume":"14","author":"Golden H. B.","year":"2009","journal-title":"Front. Biosci."},{"issue":"4","key":"ref49\/cit49","doi-asserted-by":"crossref","first-page":"1348","DOI":"10.1097\/CCM.0b013e31819cee38","volume":"37","author":"Li Y.","year":"2009","journal-title":"Crit. Care Med."},{"issue":"6","key":"ref50\/cit50","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1016\/j.micpath.2007.12.001","volume":"44","author":"Kuo S. R.","year":"2008","journal-title":"Microb. Pathog."},{"issue":"8","key":"ref51\/cit51","doi-asserted-by":"crossref","first-page":"4744","DOI":"10.1128\/IAI.00315-06","volume":"74","author":"Kubler-Kielb J.","year":"2006","journal-title":"Infect. Immun."},{"issue":"8","key":"ref52\/cit52","doi-asserted-by":"crossref","first-page":"4831","DOI":"10.1074\/jbc.M509432200","volume":"281","author":"Joyce J.","year":"2006","journal-title":"J. Biol. Chem."},{"issue":"19","key":"ref53\/cit53","doi-asserted-by":"crossref","first-page":"10925","DOI":"10.1073\/pnas.1834478100","volume":"100","author":"Rhie G. E.","year":"2003","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"issue":"6","key":"ref54\/cit54","doi-asserted-by":"crossref","first-page":"3408","DOI":"10.1128\/IAI.73.6.3408-3414.2005","volume":"73","author":"Aulinger B. A.","year":"2005","journal-title":"Infect. Immun."},{"issue":"18","key":"ref55\/cit55","doi-asserted-by":"crossref","first-page":"3953","DOI":"10.1016\/j.vaccine.2006.02.024","volume":"24","author":"Wimer-Mackin S.","year":"2006","journal-title":"Vaccine"},{"issue":"1","key":"ref56\/cit56","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/j.vaccine.2004.05.029","volume":"23","author":"Chabot D. J.","year":"2004","journal-title":"Vaccine"},{"issue":"2","key":"ref57\/cit57","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1089\/bsp.2005.3.102","volume":"3","author":"Borio L. L.","year":"2005","journal-title":"Biosecur. Bioterrorism"},{"issue":"1","key":"ref58\/cit58","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1128\/CVI.00321-07","volume":"15","author":"Taft S. C.","year":"2008","journal-title":"Clin. Vaccine Immunol."},{"issue":"17","key":"ref59\/cit59","doi-asserted-by":"crossref","first-page":"3654","DOI":"10.1016\/j.vaccine.2006.01.054","volume":"24","author":"Pittman P. R.","year":"2006","journal-title":"Vaccine"},{"issue":"18","key":"ref60\/cit60","doi-asserted-by":"crossref","first-page":"3679","DOI":"10.1016\/j.vaccine.2007.01.056","volume":"25","author":"Grunow R.","year":"2007","journal-title":"Vaccine"},{"issue":"33","key":"ref61\/cit61","doi-asserted-by":"crossref","first-page":"4262","DOI":"10.1016\/j.vaccine.2008.05.068","volume":"26","author":"Hewetson J. F.","year":"2008","journal-title":"Vaccine"},{"issue":"32","key":"ref62\/cit62","doi-asserted-by":"crossref","first-page":"5978","DOI":"10.1016\/j.vaccine.2007.05.043","volume":"25","author":"Bienek D. R.","year":"2007","journal-title":"Vaccine"},{"issue":"3","key":"ref63\/cit63","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1097\/01.jom.0000058345.05741.6b","volume":"45","author":"Wasserman G. M.","year":"2003","journal-title":"J. Occup. Environ. Med."},{"issue":"7","key":"ref64\/cit64","doi-asserted-by":"crossref","first-page":"1115","DOI":"10.1128\/CVI.00015-08","volume":"15","author":"Abboud N.","year":"2008","journal-title":"Clin. Vaccine Immunol."},{"issue":"13","key":"ref65\/cit65","doi-asserted-by":"crossref","first-page":"1532","DOI":"10.1001\/jama.300.13.1532","volume":"300","author":"Marano N.","year":"2008","journal-title":"JAMA, J. Am. Med. Assoc."},{"key":"ref66\/cit66","unstructured":"HHS Awards BioShield Contract for AVA Anthrax Vaccine News. News Release. Department of Health and Human Resources. May 6, 2005.http:\/\/www.os.dhhs.gov\/news\/press\/2005pres\/20050506.html(accessed Oct 7, 2005)."},{"issue":"2","key":"ref67\/cit67","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1586\/14787210.7.2.219","volume":"7","author":"Tournier J. N.","year":"2009","journal-title":"Expert Rev. Anti-Infect. Ther."},{"issue":"10","key":"ref68\/cit68","doi-asserted-by":"crossref","first-page":"1501","DOI":"10.1016\/j.vaccine.2005.10.018","volume":"24","author":"Hepler R. W.","year":"2006","journal-title":"Vaccine"},{"issue":"2","key":"ref69\/cit69","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1016\/j.vaccine.2006.07.037","volume":"25","author":"Duc le H.","year":"2007","journal-title":"Vaccine"},{"issue":"9","key":"ref70\/cit70","doi-asserted-by":"crossref","first-page":"5978","DOI":"10.1128\/IAI.73.9.5978-5987.2005","volume":"73","author":"Williamson E. D.","year":"2005","journal-title":"Infect. Immun."},{"issue":"33","key":"ref71\/cit71","doi-asserted-by":"crossref","first-page":"5950","DOI":"10.1016\/j.vaccine.2006.05.044","volume":"24","author":"Gorse G. J.","year":"2006","journal-title":"Vaccine"},{"issue":"20","key":"ref72\/cit72","first-page":"A23","author":"Lipton E.","year":"2006","journal-title":"N. Y. Times"},{"issue":"45","key":"ref73\/cit73","doi-asserted-by":"crossref","first-page":"5684","DOI":"10.1016\/j.vaccine.2008.08.026","volume":"26","author":"Fasanella A.","year":"2008","journal-title":"Vaccine"},{"issue":"1","key":"ref74\/cit74","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/j.pep.2004.08.007","volume":"38","author":"Laird M. W.","year":"2004","journal-title":"Protein Expression Purif."},{"issue":"5","key":"ref75\/cit75","doi-asserted-by":"crossref","first-page":"1952","DOI":"10.1128\/IAI.01722-07","volume":"76","author":"Park Y. S.","year":"2008","journal-title":"Infect. Immun."},{"issue":"4","key":"ref76\/cit76","doi-asserted-by":"crossref","first-page":"1827","DOI":"10.1128\/IAI.01242-06","volume":"75","author":"Stokes M. G.","year":"2007","journal-title":"Infect. Immun."},{"issue":"48","key":"ref77\/cit77","doi-asserted-by":"crossref","first-page":"6083","DOI":"10.1016\/j.vaccine.2008.09.010","volume":"26","author":"Baillie L. W.","year":"2008","journal-title":"Vaccine"},{"issue":"4","key":"ref78\/cit78","doi-asserted-by":"crossref","first-page":"1475","DOI":"10.1128\/IAI.00828-08","volume":"77","author":"Osorio M.","year":"2009","journal-title":"Infect. Immun."},{"issue":"8","key":"ref79\/cit79","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1016\/j.tibtech.2006.06.006","volume":"24","author":"Streatfield S. J.","year":"2006","journal-title":"Trends Biotechnol"},{"issue":"17","key":"ref80\/cit80","doi-asserted-by":"crossref","first-page":"2082","DOI":"10.1016\/j.vaccine.2005.01.013","volume":"23","author":"Hull A. K.","year":"2005","journal-title":"Vaccine"},{"issue":"6","key":"ref81\/cit81","doi-asserted-by":"crossref","first-page":"1217","DOI":"10.1007\/s11095-006-0206-9","volume":"23","author":"Sloat B. R.","year":"2006","journal-title":"Pharm. Res."},{"issue":"3","key":"ref82\/cit82","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1086\/596066","volume":"199","author":"Galen J. E.","year":"2009","journal-title":"J. Infect. Dis."},{"issue":"2","key":"ref83\/cit83","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1111\/j.1574-695X.2007.00347.x","volume":"52","author":"Sloat B. R.","year":"2008","journal-title":"FEMS Immunol. Med. Microbiol."},{"issue":"2","key":"ref84\/cit84","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1007\/s11095-005-9078-7","volume":"23","author":"Sloat B. R.","year":"2006","journal-title":"Pharm. Res."},{"issue":"1","key":"ref85\/cit85","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1002\/jps.20484","volume":"95","author":"Jiang G.","year":"2006","journal-title":"J. Pharm. Sci."},{"issue":"2","key":"ref86\/cit86","doi-asserted-by":"crossref","first-page":"1181","DOI":"10.1128\/IAI.72.2.1181-1183.2004","volume":"72","author":"Matyas G. R.","year":"2004","journal-title":"Infect. Immun."},{"issue":"1","key":"ref87\/cit87","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1038\/sj.mt.6300034","volume":"15","author":"McConnell M. J.","year":"2007","journal-title":"Mol. Ther."},{"issue":"8","key":"ref88\/cit88","doi-asserted-by":"crossref","first-page":"536","DOI":"10.4161\/hv.5.8.8725","volume":"5","author":"Keitel W. A.","year":"2009","journal-title":"Hum. Vaccines"},{"issue":"2","key":"ref89\/cit89","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1016\/j.virol.2006.05.010","volume":"353","author":"Smith M. E.","year":"2006","journal-title":"Virology"},{"issue":"2","key":"ref90\/cit90","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1038\/mt.2008.242","volume":"17","author":"Liu T. H.","year":"2009","journal-title":"Mol. Ther."},{"issue":"7","key":"ref91\/cit91","doi-asserted-by":"crossref","first-page":"1225","DOI":"10.1016\/j.vaccine.2006.10.010","volume":"25","author":"Shivachandra S. B.","year":"2007","journal-title":"Vaccine"},{"issue":"10","key":"ref92\/cit92","doi-asserted-by":"crossref","first-page":"1422","DOI":"10.1371\/journal.ppat.0030142","volume":"3","author":"Manayani D. J.","year":"2007","journal-title":"PLoS Pathog."},{"issue":"10","key":"ref93\/cit93","doi-asserted-by":"crossref","first-page":"6547","DOI":"10.1128\/IAI.73.10.6547-6551.2005","volume":"73","author":"Lim N. K.","year":"2005","journal-title":"Infect. Immun."},{"issue":"1","key":"ref94\/cit94","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1128\/IAI.00788-08","volume":"77","author":"Nguyen M. L.","year":"2009","journal-title":"Infect. Immun."},{"issue":"10","key":"ref95\/cit95","doi-asserted-by":"crossref","first-page":"3472","DOI":"10.1128\/iai.59.10.3472-3477.1991","volume":"59","author":"Pezard C.","year":"1991","journal-title":"Infect. Immun."},{"issue":"3","key":"ref96\/cit96","doi-asserted-by":"crossref","first-page":"1776","DOI":"10.4049\/jimmunol.176.3.1776","volume":"176","author":"Duverger A.","year":"2006","journal-title":"J. Immunol."},{"issue":"6","key":"ref97\/cit97","doi-asserted-by":"crossref","first-page":"1651","DOI":"10.1021\/bp049725n","volume":"20","author":"Cooksey B. A.","year":"2004","journal-title":"Biotechnol. Prog."},{"issue":"5","key":"ref98\/cit98","doi-asserted-by":"crossref","first-page":"662","DOI":"10.1016\/j.vaccine.2005.08.056","volume":"24","author":"Zeng M.","year":"2006","journal-title":"Vaccine"},{"issue":"4","key":"ref99\/cit99","doi-asserted-by":"crossref","first-page":"964","DOI":"10.1016\/j.bmcl.2005.10.088","volume":"16","author":"Xiong Y.","year":"2006","journal-title":"Bioorg. Med. Chem. Lett."},{"issue":"9","key":"ref100\/cit100","doi-asserted-by":"crossref","first-page":"3902","DOI":"10.1128\/IAI.00200-09","volume":"77","author":"Chen Z.","year":"2009","journal-title":"Infect. Immun."},{"issue":"1","key":"ref101\/cit101","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1128\/IAI.01133-06","volume":"75","author":"Kozel T. R.","year":"2007","journal-title":"Infect. Immun."},{"issue":"3","key":"ref102\/cit102","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/S0928-8244(03)00366-3","volume":"40","author":"Wang T. T.","year":"2004","journal-title":"FEMS Immunol. Med. Microbiol."},{"issue":"11","key":"ref103\/cit103","doi-asserted-by":"crossref","first-page":"5425","DOI":"10.1128\/IAI.00261-07","volume":"75","author":"Albrecht M. T.","year":"2007","journal-title":"Infect. Immun."},{"issue":"4","key":"ref104\/cit104","doi-asserted-by":"crossref","first-page":"129","DOI":"10.3233\/HAB-2003-12404","volume":"12","author":"Zhao P.","year":"2003","journal-title":"Hum. Antibodies"},{"issue":"12","key":"ref105\/cit105","doi-asserted-by":"crossref","first-page":"5790","DOI":"10.1128\/IAI.00520-08","volume":"76","author":"Rossi C. A.","year":"2008","journal-title":"Infect. Immun."},{"issue":"5","key":"ref106\/cit106","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1086\/500148","volume":"193","author":"Chen Z.","year":"2006","journal-title":"J. Infect. Dis."},{"issue":"3","key":"ref107\/cit107","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1086\/427189","volume":"191","author":"Cui X.","year":"2005","journal-title":"J. Infect. Dis."},{"issue":"2","key":"ref108\/cit108","doi-asserted-by":"crossref","first-page":"1016","DOI":"10.1128\/IAI.74.2.1016-1024.2006","volume":"74","author":"Peterson J. W.","year":"2006","journal-title":"Infect. Immun."},{"issue":"10","key":"ref109\/cit109","doi-asserted-by":"crossref","first-page":"2749","DOI":"10.1016\/j.molimm.2006.11.011","volume":"44","author":"Steiniger S. C.","year":"2007","journal-title":"Mol. Immunol."},{"issue":"7","key":"ref110\/cit110","doi-asserted-by":"crossref","first-page":"968","DOI":"10.1086\/512372","volume":"44","author":"Walsh J. J.","year":"2007","journal-title":"Clin. Infect. Dis."},{"issue":"4","key":"ref111\/cit111","doi-asserted-by":"crossref","first-page":"270","DOI":"10.7326\/0003-4819-144-4-200602210-00009","volume":"144","author":"Holty J. E.","year":"2006","journal-title":"Ann. Intern. Med."},{"issue":"1","key":"ref112\/cit112","doi-asserted-by":"crossref","first-page":"24","DOI":"10.2174\/138920108783497604","volume":"9","author":"Turk B. E.","year":"2008","journal-title":"Curr. Pharm. Biotechnol."},{"key":"ref113\/cit113","doi-asserted-by":"crossref","first-page":"1239","DOI":"10.1093\/infdis\/167.5.1239","volume":"167","author":"Friedlander A. M.","year":"1993","journal-title":"J. Infect. Dis."},{"issue":"3","key":"ref114\/cit114","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1086\/596063","volume":"199","author":"Vietri N. J.","year":"2009","journal-title":"J. Infect. Dis."},{"issue":"20","key":"ref115\/cit115","doi-asserted-by":"crossref","first-page":"7813","DOI":"10.1073\/pnas.0602748103","volume":"103","author":"Vietri N. J.","year":"2006","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"issue":"8","key":"ref116\/cit116","doi-asserted-by":"crossref","first-page":"1250","DOI":"10.1002\/cmdc.200800047","volume":"3","author":"Tipparaju S. K.","year":"2008","journal-title":"ChemMedChem"},{"issue":"2","key":"ref117\/cit117","doi-asserted-by":"crossref","first-page":"424","DOI":"10.1093\/jac\/dkh258","volume":"54","author":"Athamna A.","year":"2004","journal-title":"J. Antimicrob. Chemother."},{"issue":"9","key":"ref118\/cit118","doi-asserted-by":"crossref","first-page":"3350","DOI":"10.1128\/AAC.00360-08","volume":"52","author":"Heine H. S.","year":"2008","journal-title":"Antimicrob. Agents Chemother."},{"issue":"20","key":"ref119\/cit119","first-page":"A23","author":"Lipton E.","year":"2006","journal-title":"N. Y. Times"},{"issue":"7","key":"ref120\/cit120","doi-asserted-by":"crossref","first-page":"2711","DOI":"10.1128\/JB.188.7.2711-2714.2006","volume":"188","author":"Yoong P.","year":"2006","journal-title":"J. Bacteriol."},{"issue":"2","key":"ref121\/cit121","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1016\/j.jmb.2006.11.056","volume":"366","author":"Porter C. J.","year":"2007","journal-title":"J. Mol. Biol."},{"issue":"3","key":"ref122\/cit122","doi-asserted-by":"crossref","first-page":"626","DOI":"10.1111\/j.1365-2958.2006.05556.x","volume":"63","author":"St\u00fclke J.","year":"2007","journal-title":"Mol. Microbiol."},{"issue":"1","key":"ref123\/cit123","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1186\/1471-2334-5-25","volume":"5","author":"Popov S. G.","year":"2005","journal-title":"BMC Infect. Dis."},{"issue":"7","key":"ref124\/cit124","doi-asserted-by":"crossref","first-page":"2316","DOI":"10.1128\/AAC.01488-05","volume":"50","author":"Thwaite J. E.","year":"2006","journal-title":"Antimicrob. Agents Chemother."},{"issue":"3","key":"ref125\/cit125","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1080\/15257770701845238","volume":"27","author":"Byun Y.","year":"2008","journal-title":"Nucleosides, Nucleotides Nucleic Acids"},{"issue":"23","key":"ref126\/cit126","doi-asserted-by":"crossref","first-page":"7532","DOI":"10.1021\/jm800776a","volume":"51","author":"Beierlein J. M.","year":"2008","journal-title":"J. Med. Chem."},{"issue":"12","key":"ref127\/cit127","doi-asserted-by":"crossref","first-page":"e187","DOI":"10.1371\/journal.ppat.0030187","volume":"3","author":"Raymond B.","year":"2007","journal-title":"PLoS Pathog."},{"issue":"10","key":"ref128\/cit128","doi-asserted-by":"crossref","first-page":"6786","DOI":"10.4049\/jimmunol.175.10.6786","volume":"175","author":"Piris-Gimenez A.","year":"2005","journal-title":"J. Immunol."},{"issue":"16","key":"ref129\/cit129","doi-asserted-by":"crossref","first-page":"12112","DOI":"10.1074\/jbc.M611432200","volume":"282","author":"Akoachere M.","year":"2007","journal-title":"J. Biol. Chem."},{"issue":"1","key":"ref130\/cit130","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1016\/j.bioorg.2006.07.004","volume":"35","author":"Hanna M. L.","year":"2007","journal-title":"Bioorg. Chem."},{"issue":"9","key":"ref131\/cit131","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1038\/nchembio.2007.24","volume":"3","author":"Clatworthy A. E.","year":"2007","journal-title":"Nat. Chem. Biol."},{"issue":"1","key":"ref132\/cit132","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/j.pep.2006.04.011","volume":"49","author":"Ding Z.","year":"2006","journal-title":"Protein Expression Purif."},{"issue":"6","key":"ref133\/cit133","doi-asserted-by":"crossref","first-page":"1119","DOI":"10.1016\/j.cell.2006.03.007","volume":"124","author":"Bann J. G.","year":"2006","journal-title":"Cell"},{"issue":"5","key":"ref134\/cit134","doi-asserted-by":"crossref","first-page":"582","DOI":"10.1038\/nbt1204","volume":"24","author":"Rai P.","year":"2006","journal-title":"Nat. Biotechnol."},{"issue":"11","key":"ref135\/cit135","doi-asserted-by":"crossref","first-page":"5443","DOI":"10.1128\/IAI.00529-07","volume":"75","author":"Staats H. F.","year":"2007","journal-title":"Infect. Immun."},{"key":"ref136\/cit136","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1086\/430708","volume":"41","author":"Subramanian G. M.","year":"2005","journal-title":"Clin. Infect. Dis."},{"issue":"11","key":"ref137\/cit137","doi-asserted-by":"crossref","first-page":"6313","DOI":"10.1128\/IAI.72.11.6313-6317.2004","volume":"72","author":"Brossier F.","year":"2004","journal-title":"Infect. Immun."},{"issue":"6","key":"ref138\/cit138","doi-asserted-by":"crossref","first-page":"1047","DOI":"10.1086\/432731","volume":"192","author":"Scobie H. M.","year":"2005","journal-title":"J. Infect. Dis."},{"issue":"1","key":"ref139\/cit139","doi-asserted-by":"crossref","first-page":"602","DOI":"10.1128\/IAI.72.1.602-605.2004","volume":"72","author":"Sarac M. S.","year":"2004","journal-title":"Infect. Immun."},{"issue":"52","key":"ref140\/cit140","doi-asserted-by":"crossref","first-page":"19707","DOI":"10.1073\/pnas.0606555104","volume":"103","author":"Jiao G. S.","year":"2006","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"issue":"8","key":"ref141\/cit141","doi-asserted-by":"crossref","first-page":"5101","DOI":"10.1128\/IAI.73.8.5101-5105.2005","volume":"73","author":"Opal S. M.","year":"2005","journal-title":"Infect. Immun."},{"issue":"35","key":"ref142\/cit142","doi-asserted-by":"crossref","first-page":"36788","DOI":"10.1074\/jbc.M400484200","volume":"279","author":"Kacprzak M. M.","year":"2004","journal-title":"J. Biol. Chem."},{"issue":"9","key":"ref143\/cit143","doi-asserted-by":"crossref","first-page":"3875","DOI":"10.1128\/AAC.49.9.3875-3882.2005","volume":"49","author":"Komiyama T.","year":"2005","journal-title":"Antimicrob. Agents Chemother."},{"issue":"3","key":"ref144\/cit144","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1016\/j.bbrc.2004.07.012","volume":"321","author":"Peinado J. R.","year":"2004","journal-title":"Biochem. Biophys. Res. Commun."},{"issue":"29","key":"ref145\/cit145","doi-asserted-by":"crossref","first-page":"20847","DOI":"10.1074\/jbc.M703847200","volume":"282","author":"Shiryaev S. A.","year":"2007","journal-title":"J. Biol. Chem."},{"issue":"8","key":"ref146\/cit146","doi-asserted-by":"crossref","first-page":"2658","DOI":"10.1128\/AAC.01412-05","volume":"50","author":"Moayeri M.","year":"2006","journal-title":"Antimicrob. Agents Chemother."},{"issue":"5735","key":"ref147\/cit147","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1126\/science.1113380","volume":"309","author":"Krantz B. A.","year":"2005","journal-title":"Science"},{"issue":"5","key":"ref148\/cit148","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1021\/mp050040f","volume":"2","author":"Gujraty K.","year":"2005","journal-title":"Mol. Pharmaceutics"},{"issue":"2","key":"ref149\/cit149","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1002\/pro.35","volume":"18","author":"Janowiak B. E.","year":"2009","journal-title":"Protein Sci."},{"issue":"2","key":"ref150\/cit150","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1083\/jcb.200507067","volume":"172","author":"Abrami L.","year":"2006","journal-title":"J. Cell Biol."},{"issue":"2","key":"ref151\/cit151","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1038\/labinvest.3700505","volume":"87","author":"Hirsh M. I.","year":"2007","journal-title":"Lab. Invest."},{"issue":"7","key":"ref152\/cit152","doi-asserted-by":"crossref","first-page":"1003","DOI":"10.1086\/507311","volume":"194","author":"Hirsh M. I.","year":"2006","journal-title":"J. Infect. Dis."},{"issue":"7","key":"ref153\/cit153","doi-asserted-by":"crossref","first-page":"3707","DOI":"10.1128\/IAI.00051-06","volume":"74","author":"Moayeri M.","year":"2006","journal-title":"Infect. Immun."},{"issue":"7","key":"ref154\/cit154","doi-asserted-by":"crossref","first-page":"2403","DOI":"10.1128\/AAC.01184-06","volume":"51","author":"Sanchez A. M.","year":"2007","journal-title":"Antimicrob. Agents Chemother."},{"issue":"16","key":"ref155\/cit155","doi-asserted-by":"crossref","first-page":"5424","DOI":"10.1016\/j.bmc.2007.05.058","volume":"15","author":"Karginov V. A.","year":"2007","journal-title":"Bioorg. Med. Chem."},{"issue":"1","key":"ref156\/cit156","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.bmc.2005.07.054","volume":"14","author":"Karginov V. A.","year":"2006","journal-title":"Bioorg. Med. Chem."},{"issue":"11","key":"ref157\/cit157","doi-asserted-by":"crossref","first-page":"3740","DOI":"10.1128\/AAC.00693-06","volume":"50","author":"Karginov V. A.","year":"2006","journal-title":"Antimicrob. Agents Chemother."},{"issue":"1","key":"ref158\/cit158","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1128\/AAC.00983-06","volume":"51","author":"Backer M. V.","year":"2007","journal-title":"Antimicrob. Agents Chemother."},{"issue":"1","key":"ref159\/cit159","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1016\/j.bioorg.2006.07.004","volume":"35","author":"Hanna M. L.","year":"2007","journal-title":"Bioorg. Chem."},{"issue":"16","key":"ref160\/cit160","doi-asserted-by":"crossref","first-page":"4575","DOI":"10.1016\/j.bmcl.2007.05.089","volume":"17","author":"Gaddis B. D.","year":"2007","journal-title":"Bioorg. Med. Chem. Lett."},{"issue":"1","key":"ref161\/cit161","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1038\/nsmb708","volume":"11","author":"Turk B. E.","year":"2004","journal-title":"Nat. Struct. Mol. Biol."},{"issue":"4","key":"ref162\/cit162","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1016\/j.bioorg.2006.12.005","volume":"35","author":"Johnson S. L.","year":"2007","journal-title":"Bioorg. Chem."},{"issue":"5","key":"ref163\/cit163","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1021\/mp8000149","volume":"5","author":"Verma R. P.","year":"2008","journal-title":"Mol. Pharmaceutics"},{"issue":"3","key":"ref164\/cit164","doi-asserted-by":"crossref","first-page":"290","DOI":"10.2174\/138955708783744083","volume":"8","author":"Dalkas G. A.","year":"2008","journal-title":"Mini-Rev. Med. Chem."},{"issue":"13","key":"ref165\/cit165","doi-asserted-by":"crossref","first-page":"3054","DOI":"10.1111\/j.1742-4658.2006.05316.x","volume":"273","author":"Kuzmic P.","year":"2006","journal-title":"FEBS J."},{"key":"ref166\/cit166","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1186\/1471-2210-6-8","volume":"6","author":"Goldman M. E.","year":"2006","journal-title":"BMC Pharmacol."},{"issue":"2","key":"ref167\/cit167","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1111\/j.1747-0285.2007.00617.x","volume":"71","author":"Johnson S. L.","year":"2008","journal-title":"Chem. Biol. Drug Des."},{"issue":"4","key":"ref168\/cit168","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1038\/sj.embor.7400118","volume":"5","author":"Dell'Aica I.","year":"2004","journal-title":"EMBO Rep."},{"issue":"22","key":"ref169\/cit169","doi-asserted-by":"crossref","first-page":"7958","DOI":"10.1073\/pnas.0502159102","volume":"102","author":"Shoop W. L.","year":"2005","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"issue":"50","key":"ref170\/cit170","doi-asserted-by":"crossref","first-page":"8410","DOI":"10.1016\/j.vaccine.2007.09.063","volume":"25","author":"Gupta M.","year":"2007","journal-title":"Vaccine"},{"issue":"17","key":"ref171\/cit171","doi-asserted-by":"crossref","first-page":"5232","DOI":"10.1021\/jm0605132","volume":"49","author":"Schepetkin I. A.","year":"2006","journal-title":"J. Med. Chem."},{"issue":"4","key":"ref172\/cit172","doi-asserted-by":"crossref","first-page":"1063","DOI":"10.1021\/jm8013212","volume":"52","author":"Agrawal A.","year":"2009","journal-title":"J. Med. Chem."},{"issue":"8","key":"ref173\/cit173","doi-asserted-by":"crossref","first-page":"2758","DOI":"10.1128\/AAC.01528-06","volume":"51","author":"Pelat T.","year":"2007","journal-title":"Antimicrob. Agents Chemother."},{"issue":"5","key":"ref174\/cit174","doi-asserted-by":"crossref","first-page":"e1000456","DOI":"10.1371\/journal.ppat.1000456","volume":"5","author":"Moayeri M.","year":"2009","journal-title":"PLoS Pathog."},{"issue":"3","key":"ref175\/cit175","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1002\/prot.21249","volume":"67","author":"Chen D.","year":"2007","journal-title":"Proteins"},{"issue":"28","key":"ref176\/cit176","doi-asserted-by":"crossref","first-page":"25990","DOI":"10.1074\/jbc.M301232200","volume":"278","author":"Soelaiman S.","year":"2003","journal-title":"J. Biol. Chem."},{"issue":"9","key":"ref177\/cit177","doi-asserted-by":"crossref","first-page":"3242","DOI":"10.1073\/pnas.0306552101","volume":"101","author":"Shen Y.","year":"2004","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"issue":"3","key":"ref178\/cit178","first-page":"459","volume":"45","author":"Dong D. Y.","year":"2005","journal-title":"Weishengwu Xuebao"},{"issue":"15","key":"ref179\/cit179","doi-asserted-by":"crossref","first-page":"7225","DOI":"10.1016\/j.bmc.2008.06.036","volume":"16","author":"Chen D.","year":"2008","journal-title":"Bioorg. Med. Chem."},{"issue":"2","key":"ref180\/cit180","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1002\/prot.22241","volume":"75","author":"Joshi M.","year":"2009","journal-title":"Proteins"},{"key":"ref181\/cit181","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1134\/S1607672908010043","volume":"418","author":"Zakharova M. Y.","year":"2008","journal-title":"Dokl. Biochem. Biophys."},{"issue":"27","key":"ref182\/cit182","doi-asserted-by":"crossref","first-page":"17902","DOI":"10.1074\/jbc.M807510200","volume":"284","author":"Zakharova M. Y.","year":"2009","journal-title":"J. Biol. Chem."},{"issue":"9","key":"ref183\/cit183","doi-asserted-by":"crossref","first-page":"e3130","DOI":"10.1371\/journal.pone.0003130","volume":"3","author":"Gupta P. K.","year":"2008","journal-title":"PLoS One"},{"issue":"6","key":"ref184\/cit184","doi-asserted-by":"crossref","first-page":"1352","DOI":"10.1111\/j.1462-5822.2008.01131.x","volume":"10","author":"Wickliffe K. E.","year":"2008","journal-title":"Cell. Microbiol."},{"issue":"1","key":"ref185\/cit185","doi-asserted-by":"crossref","first-page":"e1421","DOI":"10.1371\/journal.pone.0001421","volume":"3","author":"Chapelsky S.","year":"2008","journal-title":"PLoS One"},{"issue":"13","key":"ref186\/cit186","doi-asserted-by":"crossref","first-page":"4830","DOI":"10.1073\/pnas.0500508102","volume":"102","author":"Kim C.","year":"2005","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"issue":"43","key":"ref187\/cit187","doi-asserted-by":"crossref","first-page":"32755","DOI":"10.1074\/jbc.M603614200","volume":"281","author":"Wang W.","year":"2006","journal-title":"J. Biol. Chem."},{"issue":"6","key":"ref188\/cit188","doi-asserted-by":"crossref","first-page":"758","DOI":"10.4161\/cc.6.6.3991","volume":"6","author":"Muehlbauer S. M.","year":"2007","journal-title":"Cell Cycle"},{"issue":"2","key":"ref189\/cit189","first-page":"332","volume":"10","author":"Wickliffe K. E.","year":"2008","journal-title":"Cell. Microbiol."},{"issue":"8","key":"ref190\/cit190","doi-asserted-by":"crossref","first-page":"1139","DOI":"10.1016\/j.chembiol.2004.05.020","volume":"11","author":"Lee Y. S.","year":"2004","journal-title":"Chem. Biol."},{"issue":"4","key":"ref191\/cit191","doi-asserted-by":"crossref","first-page":"1895","DOI":"10.1128\/IAI.01632-06","volume":"75","author":"Tessier J.","year":"2007","journal-title":"Infect. Immun."},{"issue":"7","key":"ref192\/cit192","doi-asserted-by":"crossref","first-page":"3987","DOI":"10.1128\/IAI.00174-06","volume":"74","author":"Gat O.","year":"2006","journal-title":"Infect. Immun."},{"issue":"6935","key":"ref193\/cit193","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1038\/nature01586","volume":"423","author":"Read T. D.","year":"2003","journal-title":"Nature"},{"issue":"17","key":"ref194\/cit194","doi-asserted-by":"crossref","first-page":"6425","DOI":"10.1128\/JB.00702-07","volume":"189","author":"Marraffini L. A.","year":"2007","journal-title":"J. Bacteriol."},{"key":"ref195\/cit195","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1186\/1471-2180-6-56","volume":"6","author":"Mosser E. M.","year":"2006","journal-title":"BMC Microbiol."},{"issue":"41","key":"ref196\/cit196","doi-asserted-by":"crossref","first-page":"7197","DOI":"10.1016\/j.vaccine.2007.07.040","volume":"25","author":"Cowan G. J.","year":"2007","journal-title":"Vaccine"},{"issue":"5","key":"ref197\/cit197","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1107\/S174430910501095X","volume":"61","author":"Grenha R.","year":"2005","journal-title":"Acta Crystallogr., Sect. F: Struct. Biol. Cryst. Commun."},{"issue":"8","key":"ref198\/cit198","doi-asserted-by":"crossref","first-page":"2829","DOI":"10.1128\/JB.188.8.2829-2835.2006","volume":"188","author":"Tinsley E.","year":"2006","journal-title":"J. Bacteriol."},{"key":"ref199\/cit199","first-page":"29","volume":"1","author":"Mikshis N. I.","year":"2006","journal-title":"Zh. Mikrobiol., Epidemiol. Immunobiol."},{"issue":"42","key":"ref200\/cit200","first-page":"31408","volume":"281","author":"Chung M. C.","year":"2006","journal-title":"J. Biol. Chem."},{"issue":"2","key":"ref201\/cit201","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1586\/14789450.2.2.187","volume":"2","author":"Zhang C. G.","year":"2005","journal-title":"Expert Rev. Proteomics"},{"issue":"50","key":"ref202\/cit202","doi-asserted-by":"crossref","first-page":"17946","DOI":"10.1073\/pnas.0506410102","volume":"102","author":"Torrents E.","year":"2005","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"issue":"3","key":"ref203\/cit203","doi-asserted-by":"crossref","first-page":"1009","DOI":"10.1073\/pnas.0710950105","volume":"105","author":"Shatalin K.","year":"2008","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"issue":"1","key":"ref204\/cit204","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1111\/j.1574-6968.2007.00713.x","volume":"271","author":"Heffernan B. J.","year":"2007","journal-title":"FEMS Microbiol. Lett."},{"issue":"13","key":"ref205\/cit205","doi-asserted-by":"crossref","first-page":"4147","DOI":"10.1021\/bi6023995","volume":"46","author":"Pfleger B. F.","year":"2007","journal-title":"Biochemistry"},{"issue":"5","key":"ref206\/cit206","doi-asserted-by":"crossref","first-page":"1698","DOI":"10.1128\/JB.01526-06","volume":"189","author":"Lee J. Y.","year":"2007","journal-title":"J. Bacteriol."},{"issue":"49","key":"ref207\/cit207","doi-asserted-by":"crossref","first-page":"18499","DOI":"10.1073\/pnas.0607055103","volume":"103","author":"Abergel R. J.","year":"2006","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"issue":"2","key":"ref208\/cit208","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1099\/mic.0.2007\/008292-0","volume":"154","author":"Cote C. K.","year":"2008","journal-title":"Microbiology"},{"issue":"3","key":"ref209\/cit209","doi-asserted-by":"crossref","first-page":"1197","DOI":"10.1128\/IAI.01217-08","volume":"77","author":"Gauthier Y. P.","year":"2009","journal-title":"Infect. Immun."},{"issue":"9","key":"ref210\/cit210","doi-asserted-by":"crossref","first-page":"6355","DOI":"10.1128\/AEM.00455-06","volume":"72","author":"Delvecchio V. G.","year":"2006","journal-title":"Appl. Environ. Microbiol."},{"issue":"21","key":"ref211\/cit211","doi-asserted-by":"crossref","first-page":"4569","DOI":"10.1016\/j.vaccine.2005.08.031","volume":"24","author":"Hahn U. K.","year":"2006","journal-title":"Vaccine"},{"issue":"36","key":"ref212\/cit212","doi-asserted-by":"crossref","first-page":"9136","DOI":"10.1002\/chem.200601245","volume":"12","author":"Mehta A. S.","year":"2006","journal-title":"Chemistry"},{"issue":"2","key":"ref213\/cit213","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1099\/mic.0.26681-0","volume":"150","author":"Redmond C.","year":"2004","journal-title":"Microbiology"},{"issue":"8","key":"ref214\/cit214","doi-asserted-by":"crossref","first-page":"2413","DOI":"10.1128\/JB.186.8.2413-2417.2004","volume":"186","author":"Kim H. S.","year":"2004","journal-title":"J. Bacteriol."},{"issue":"6","key":"ref215\/cit215","doi-asserted-by":"crossref","first-page":"2841","DOI":"10.1128\/IAI.02029-06","volume":"75","author":"Chitlaru T.","year":"2007","journal-title":"Infect. Immun."},{"issue":"2","key":"ref216\/cit216","doi-asserted-by":"crossref","first-page":"404","DOI":"10.1111\/j.1365-2958.2008.06533.x","volume":"71","author":"Richter S.","year":"2009","journal-title":"Mol. Microbiol."},{"issue":"1","key":"ref217\/cit217","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1128\/AAC.00706-06","volume":"51","author":"Scorpio A.","year":"2007","journal-title":"Antimicrob. Agents Chemother."},{"issue":"3","key":"ref218\/cit218","doi-asserted-by":"crossref","first-page":"1014","DOI":"10.1128\/AAC.00741-07","volume":"52","author":"Scorpio A.","year":"2008","journal-title":"Antimicrob. Agents Chemother."},{"issue":"5","key":"ref219\/cit219","doi-asserted-by":"crossref","first-page":"1265","DOI":"10.1021\/bc060042y","volume":"17","author":"Joshi A.","year":"2006","journal-title":"Bioconjugate Chem."},{"issue":"6","key":"ref220\/cit220","doi-asserted-by":"crossref","first-page":"2291","DOI":"10.1073\/pnas.90.6.2291","volume":"90","author":"Abramova F. A.","year":"1993","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"issue":"2","key":"ref221\/cit221","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1007\/BF03160961","volume":"4","author":"Wills B.","year":"2008","journal-title":"J. Med. Toxicol."},{"issue":"7","key":"ref222\/cit222","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1001\/archinte.167.7.655","volume":"167","author":"Schmitt B.","year":"2007","journal-title":"Arch. Intern. Med."},{"issue":"1","key":"ref223\/cit223","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1097\/SHK.0b013e318067dcfe","volume":"29","author":"Kumar R.","year":"2008","journal-title":"Shock"},{"issue":"1","key":"ref224\/cit224","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1089\/bsp.2006.0001","volume":"5","author":"Baccam P.","year":"2007","journal-title":"Biosecur. Bioterrorism"},{"key":"ref225\/cit225","unstructured":"Centers for Disease Control and Prevention. Emergency Preparedness and Response, Anthrax Q & A: Preventive Therapy. Updated March 25, 2005.http:\/\/www.bt.cdc.gov\/agent\/anthrax\/faq\/preventive.asp(accessed May 10, 2005)."},{"issue":"3","key":"ref226\/cit226","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1089\/bsp.2006.4.244","volume":"4","author":"Bravata D. M.","year":"2006","journal-title":"Biosecur. Bioterrorism"},{"issue":"3","key":"ref227\/cit227","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1177\/0272989X07312721","volume":"28","author":"Zaric G. S.","year":"2008","journal-title":"Med. Decis. Making"},{"issue":"8","key":"ref228\/cit228","doi-asserted-by":"crossref","first-page":"601","DOI":"10.7326\/0003-4819-142-8-200504190-00008","volume":"142","author":"Fowler R. A.","year":"2005","journal-title":"Ann. Intern. Med."},{"issue":"11","key":"ref229\/cit229","doi-asserted-by":"crossref","first-page":"522","DOI":"10.1016\/j.tim.2009.08.006","volume":"17","author":"Bouzianas D. G.","year":"2009","journal-title":"Trends Microbiol."},{"issue":"2","key":"ref230\/cit230","doi-asserted-by":"crossref","first-page":"433","DOI":"10.2353\/ajpath.2006.051330","volume":"169","author":"Stearns-Kurosawa D. J.","year":"2006","journal-title":"Am. J. Pathol."},{"issue":"2","key":"ref231\/cit231","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1111\/j.0959-9673.2006.00473.x","volume":"87","author":"Duong S.","year":"2006","journal-title":"Int. J. Exp. Pathol."},{"issue":"8","key":"ref232\/cit232","doi-asserted-by":"crossref","first-page":"4801","DOI":"10.1128\/IAI.72.8.4801-4809.2004","volume":"72","author":"Lyons C. R.","year":"2004","journal-title":"Infect. Immun."},{"issue":"18","key":"ref233\/cit233","doi-asserted-by":"crossref","first-page":"3679","DOI":"10.1016\/j.vaccine.2007.01.056","volume":"25","author":"Grunow R.","year":"2007","journal-title":"Vaccine"},{"issue":"4","key":"ref234\/cit234","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1128\/MMBR.68.4.617-629.2004","volume":"68","author":"Phipps A. J.","year":"2004","journal-title":"Microbiol. Mol. Biol. Rev."},{"issue":"1","key":"ref235\/cit235","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1128\/IAI.74.1.394-398.2006","volume":"74","author":"Weiss S.","year":"2006","journal-title":"Infect. Immun."},{"issue":"4","key":"ref236\/cit236","doi-asserted-by":"crossref","first-page":"1649","DOI":"10.1128\/IAI.00530-08","volume":"77","author":"Skoble J.","year":"2009","journal-title":"Infect. Immun."},{"issue":"3","key":"ref237\/cit237","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1016\/j.vaccine.2003.07.004","volume":"22","author":"Little S. F.","year":"2004","journal-title":"Vaccine"},{"key":"ref238\/cit238","unstructured":"New Drug and Biological Drug Products. Evidence Needed To Demonstrate Effectiveness of New Drugs When Human Efficacy Studies Are Not Ethical or Feasible1; 21CFR 314 and 601;U.S. Food and Drug Administration and U.S. Department of Health and Human Services:Rockville, MD, 2002."},{"issue":"5","key":"ref239\/cit239","doi-asserted-by":"crossref","first-page":"716","DOI":"10.1354\/vp.44-5-716","volume":"44","author":"Twenhafel N. A.","year":"2007","journal-title":"Vet. Pathol."},{"issue":"12","key":"ref240\/cit240","doi-asserted-by":"crossref","first-page":"5790","DOI":"10.1128\/IAI.00520-08","volume":"76","author":"Rossi C. A.","year":"2008","journal-title":"Infect. Immun."},{"issue":"6","key":"ref241\/cit241","doi-asserted-by":"crossref","first-page":"2689","DOI":"10.1128\/IAI.01875-06","volume":"75","author":"Loving C. L.","year":"2007","journal-title":"Infect. Immun."},{"issue":"7","key":"ref242\/cit242","doi-asserted-by":"crossref","first-page":"947","DOI":"10.1016\/j.vaccine.2007.11.087","volume":"26","author":"Yan M.","year":"2008","journal-title":"Vaccine"},{"issue":"11","key":"ref243\/cit243","doi-asserted-by":"crossref","first-page":"3973","DOI":"10.1128\/AAC.00453-08","volume":"52","author":"Drusano G. L.","year":"2008","journal-title":"Antimicrob. Agents Chemother."},{"key":"ref244\/cit244","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1186\/1471-2334-8-124","volume":"8","author":"Hammamieh R.","year":"2008","journal-title":"BMC Infect. Dis."},{"issue":"3","key":"ref245\/cit245","doi-asserted-by":"crossref","first-page":"1157","DOI":"10.1529\/biophysj.107.121715","volume":"95","author":"Nablo B. J.","year":"2008","journal-title":"Biophys. J."}],"container-title":["Journal of Medicinal Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/jm901024b","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,5]],"date-time":"2023-04-05T05:34:41Z","timestamp":1680672881000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/jm901024b"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,1,26]]},"references-count":245,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2010,6,10]]}},"alternative-id":["10.1021\/jm901024b"],"URL":"https:\/\/doi.org\/10.1021\/jm901024b","relation":{},"ISSN":["0022-2623","1520-4804"],"issn-type":[{"value":"0022-2623","type":"print"},{"value":"1520-4804","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,1,26]]}}}