{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T05:45:55Z","timestamp":1760852755344},"reference-count":29,"publisher":"American Chemical Society (ACS)","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Med. Chem."],"published-print":{"date-parts":[[2000,3,1]]},"DOI":"10.1021\/jm9905561","type":"journal-article","created":{"date-parts":[[2002,7,26]],"date-time":"2002-07-26T05:59:58Z","timestamp":1027663198000},"page":"1215-1222","source":"Crossref","is-referenced-by-count":43,"title":["Further SAR Studies of Piperidine-Based Analogues of Cocaine. 2. Potent Dopamine and Serotonin Reuptake Inhibitors"],"prefix":"10.1021","volume":"43","author":[{"given":"Amir P.","family":"Tamiz","sequence":"first","affiliation":[{"name":"Drug Discovery Program, Institute of Cognitive and Computational Science, Georgetown University Medical Center, 3970 Reservoir Road, NW, Washington, DC 20007-2197, Department of Pharmacology and Toxicology, University of Texas Medical Branch, Galveston, Texas 77555-1031, and Laboratory for the Structure of Matter, Code 6030, Naval Research Laboratory, 4555 Overlook, SW, Washington, DC 20275-5000."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jianrong","family":"Zhang","sequence":"additional","affiliation":[{"name":"Drug Discovery Program, Institute of Cognitive and Computational Science, Georgetown University Medical Center, 3970 Reservoir Road, NW, Washington, DC 20007-2197, Department of Pharmacology and Toxicology, University of Texas Medical Branch, Galveston, Texas 77555-1031, and Laboratory for the Structure of Matter, Code 6030, Naval Research Laboratory, 4555 Overlook, SW, Washington, DC 20275-5000."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Judith L.","family":"Flippen-Anderson","sequence":"additional","affiliation":[{"name":"Drug Discovery Program, Institute of Cognitive and Computational Science, Georgetown University Medical Center, 3970 Reservoir Road, NW, Washington, DC 20007-2197, Department of Pharmacology and Toxicology, University of Texas Medical Branch, Galveston, Texas 77555-1031, and Laboratory for the Structure of Matter, Code 6030, Naval Research Laboratory, 4555 Overlook, SW, Washington, DC 20275-5000."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mei","family":"Zhang","sequence":"additional","affiliation":[{"name":"Drug Discovery Program, Institute of Cognitive and Computational Science, Georgetown University Medical Center, 3970 Reservoir Road, NW, Washington, DC 20007-2197, Department of Pharmacology and Toxicology, University of Texas Medical Branch, Galveston, Texas 77555-1031, and Laboratory for the Structure of Matter, Code 6030, Naval Research Laboratory, 4555 Overlook, SW, Washington, DC 20275-5000."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kenneth M.","family":"Johnson","sequence":"additional","affiliation":[{"name":"Drug Discovery Program, Institute of Cognitive and Computational Science, Georgetown University Medical Center, 3970 Reservoir Road, NW, Washington, DC 20007-2197, Department of Pharmacology and Toxicology, University of Texas Medical Branch, Galveston, Texas 77555-1031, and Laboratory for the Structure of Matter, Code 6030, Naval Research Laboratory, 4555 Overlook, SW, Washington, DC 20275-5000."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Olivier","family":"Deschaux","sequence":"additional","affiliation":[{"name":"Drug Discovery Program, Institute of Cognitive and Computational Science, Georgetown University Medical Center, 3970 Reservoir Road, NW, Washington, DC 20007-2197, Department of Pharmacology and Toxicology, University of Texas Medical Branch, Galveston, Texas 77555-1031, and Laboratory for the Structure of Matter, Code 6030, Naval Research Laboratory, 4555 Overlook, SW, Washington, DC 20275-5000."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Srihari","family":"Tella","sequence":"additional","affiliation":[{"name":"Drug Discovery Program, Institute of Cognitive and Computational Science, Georgetown University Medical Center, 3970 Reservoir Road, NW, Washington, DC 20007-2197, Department of Pharmacology and Toxicology, University of Texas Medical Branch, Galveston, Texas 77555-1031, and Laboratory for the Structure of Matter, Code 6030, Naval Research Laboratory, 4555 Overlook, SW, Washington, DC 20275-5000."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alan P.","family":"Kozikowski","sequence":"additional","affiliation":[{"name":"Drug Discovery Program, Institute of Cognitive and Computational Science, Georgetown University Medical Center, 3970 Reservoir Road, NW, Washington, DC 20007-2197, Department of Pharmacology and Toxicology, University of Texas Medical Branch, Galveston, Texas 77555-1031, and Laboratory for the Structure of Matter, Code 6030, Naval Research Laboratory, 4555 Overlook, SW, Washington, DC 20275-5000."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"316","published-online":{"date-parts":[[2000,2,25]]},"reference":[{"key":"jm9905561b00001\/jm9905561b00001_1","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1007\/BF00179933","volume":"93","author":"Thomas D. R.","year":"1987","journal-title":"Psychopharmacology"},{"key":"jm9905561b00002\/jm9905561b00002_1","first-page":"441","volume":"57","author":"Wong D. T.","year":"1995","journal-title":"Life Sci."},{"key":"jm9905561b00003\/jm9905561b00003_1","first-page":"638","volume":"52","author":"Dechant K. L.","year":"1991","journal-title":"Drugs"},{"key":"jm9905561b00004\/jm9905561b00004_1","first-page":"325","volume":"13","author":"Pinder R. M.","year":"1993","journal-title":"Antidepressants. Med. Res. Rev."},{"key":"jm9905561b00004\/jm9905561b00004_2","doi-asserted-by":"crossref","first-page":"480","DOI":"10.2174\/0929867306666220330184544","volume":"6","author":"Pacher P.","year":"1999","journal-title":"Curr. Med. Chem."},{"key":"jm9905561b00004\/jm9905561b00004_3","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1002\/hup.470030203","volume":"3","author":"Pinder R. M","year":"1988","journal-title":"Hum. Psychopharmacol."},{"key":"jm9905561b00005\/jm9905561b00005_1","doi-asserted-by":"crossref","first-page":"4339","DOI":"10.1021\/jm970525a","volume":"40","author":"Agoston G. E.","year":"1997","journal-title":"J. Med. Chem."},{"key":"jm9905561b00005\/jm9905561b00005_2","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1001\/archpsyc.1995.03950180073010","volume":"52","author":"Klein R. G","year":"1995","journal-title":"Arch. Gen. Psychiatry"},{"key":"jm9905561b00006\/jm9905561b00006_1","first-page":"16","volume":"42","year":"1999","journal-title":"J. Med. Chem."},{"key":"jm9905561b00007\/jm9905561b00007_1","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1111\/j.1749-6632.1998.tb08222.x","volume":"844","author":"Rothman R. B.","year":"1998","journal-title":"Ann. N.Y. Acad. Sci."},{"key":"jm9905561b00008\/jm9905561b00008_1","first-page":"1559","volume":"276","author":"Howell L. L.","year":"1996","journal-title":"J. Pharmcol. Exp. Ther."},{"key":"jm9905561b00009\/jm9905561b00009_1","first-page":"S86","volume":"106","author":"Frances A.","year":"1992","journal-title":"Psychopharamacology Suppl."},{"key":"jm9905561b00009\/jm9905561b00009_2","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1016\/S0925-4927(98)00041-9","volume":"84","author":"Brody A. L.","year":"1998","journal-title":"Psychiatry Res."},{"key":"jm9905561b00010\/jm9905561b00010_1","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1016\/0376-8716(96)01233-1","volume":"41","author":"Batki S. L.","year":"1996","journal-title":"Drug Alcohol Depend."},{"key":"jm9905561b00011\/jm9905561b00011_1","first-page":"156","volume":"42","author":"Hitzig P","year":"1993","journal-title":"Maryland Med. J."},{"key":"jm9905561b00012\/jm9905561b00012_1","first-page":"401","volume":"56","author":"Ascher J. A.","year":"1995","journal-title":"J. Clin. Psychiatry"},{"key":"jm9905561b00013\/jm9905561b00013_1","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1055\/s-2007-1014417","volume":"25","author":"Benkert O.","year":"1992","journal-title":"Pharmacopsychiatry"},{"key":"jm9905561b00014\/jm9905561b00014_1","doi-asserted-by":"crossref","first-page":"145","DOI":"10.4088\/JCP.v58n0401","volume":"58","author":"Bodkin J. A.","year":"1997","journal-title":"J. Clin. Psychiatry"},{"key":"jm9905561b00015\/jm9905561b00015_1","first-page":"245","volume":"9","author":"Labbate L. A.","year":"1997","journal-title":"Ann. Clin. Psychiatry"},{"key":"jm9905561b00016\/jm9905561b00016_1","first-page":"53","volume":"6","author":"Sambunaris A.","year":"1997","journal-title":"J. Clin. Psychiatry"},{"key":"jm9905561b00017\/jm9905561b00017_1","first-page":"1969","volume":"41","author":"Kozikowski A. P.","year":"1998","journal-title":"J. Med. Chem."},{"key":"jm9905561b00018\/jm9905561b00018_1","first-page":"9073","volume":"120","author":"Smith M. P.","year":"1998","journal-title":"J. Am. Chem. Soc."},{"key":"jm9905561b00019\/jm9905561b00019_1","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1021\/jo00028a043","volume":"57","author":"Tsuji R.","year":"1992","journal-title":"J. Org. Chem."},{"key":"jm9905561b00020\/jm9905561b00020_1","doi-asserted-by":"crossref","first-page":"4035","DOI":"10.1021\/jm960409s","volume":"39","author":"Blough B. E.","year":"1996","journal-title":"J. Med. Chem."},{"key":"jm9905561b00021\/jm9905561b00021_1","first-page":"189","volume":"199","author":"Yi S. -J.","year":"1991","journal-title":"Eu. J. Pharm."},{"key":"jm9905561b00021\/jm9905561b00021_2","first-page":"486","volume":"29","author":"Yi S. -J.","year":"1991","journal-title":"Neuropharmacology"},{"key":"jm9905561b00021\/jm9905561b00021_3","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1016\/S0376-8716(97)00102-6","volume":"48","author":"Slusher B. S.","year":"1997","journal-title":"Drug Alcohol Depend."},{"key":"jm9905561b00022\/jm9905561b00022_1","first-page":"2558","volume":"39","author":"Davis H. M. L.","year":"1996","journal-title":"J. Med. Chem."},{"key":"jm9905561b00023\/jm9905561b00023_1","first-page":"53","volume":"6","author":"Sambunaris A.","year":"1997","journal-title":"J. Clin. Psychiatry."}],"container-title":["Journal of Medicinal Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/jm9905561","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,20]],"date-time":"2023-04-20T10:35:23Z","timestamp":1681986923000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/jm9905561"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2000,2,25]]},"references-count":29,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2000,3,1]]}},"alternative-id":["10.1021\/jm9905561"],"URL":"https:\/\/doi.org\/10.1021\/jm9905561","relation":{},"ISSN":["0022-2623","1520-4804"],"issn-type":[{"value":"0022-2623","type":"print"},{"value":"1520-4804","type":"electronic"}],"subject":[],"published":{"date-parts":[[2000,2,25]]}}}