{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T19:54:23Z","timestamp":1787860463095,"version":"build-2784847793"},"reference-count":24,"publisher":"American Chemical Society (ACS)","issue":"22","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Med. Chem."],"published-print":{"date-parts":[[2000,11,1]]},"DOI":"10.1021\/jm990614i","type":"journal-article","created":{"date-parts":[[2002,7,26]],"date-time":"2002-07-26T05:59:58Z","timestamp":1027663198000},"page":"4169-4179","source":"Crossref","is-referenced-by-count":55,"title":["The Mitochondrial Monoamine Oxidase\u2212Aldehyde Dehydrogenase Pathway:\u2009 A Potential Site of Action of Daidzin"],"prefix":"10.1021","volume":"43","author":[{"given":"Nad\u00e8ge","family":"Rooke","sequence":"first","affiliation":[{"name":"Center for Biochemical and Biophysical Sciences and Medicine, Harvard Medical School, 250 Longwood Avenue, Boston, Massachusetts 02115"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dian-Jun","family":"Li","sequence":"additional","affiliation":[{"name":"Center for Biochemical and Biophysical Sciences and Medicine, Harvard Medical School, 250 Longwood Avenue, Boston, Massachusetts 02115"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junqing","family":"Li","sequence":"additional","affiliation":[{"name":"Center for Biochemical and Biophysical Sciences and Medicine, Harvard Medical School, 250 Longwood Avenue, Boston, Massachusetts 02115"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wing Ming","family":"Keung","sequence":"additional","affiliation":[{"name":"Center for Biochemical and Biophysical Sciences and Medicine, Harvard Medical School, 250 Longwood Avenue, Boston, Massachusetts 02115"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2000,10,6]]},"reference":[{"key":"jm990614ib00001\/jm990614ib00001_1","first-page":"10012","volume":"90","author":"Keung W. M.","year":"1993","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"jm990614ib00002\/jm990614ib00002_1","doi-asserted-by":"crossref","first-page":"1087","DOI":"10.1111\/j.1530-0277.1996.tb01950.x","volume":"20","author":"Heyman G. M.","year":"1996","journal-title":"Alcohol. Clin. Exp. Res."},{"key":"jm990614ib00003\/jm990614ib00003_1","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1111\/j.1530-0277.1996.tb01633.x","volume":"20","author":"Overstreet D. H.","year":"1996","journal-title":"Alcohol. Clin. Exp. Res."},{"key":"jm990614ib00004\/jm990614ib00004_1","first-page":"663","volume":"20","author":"Lin R. C.","year":"1996","journal-title":"Alcohol. Clin. Exp. Res."},{"key":"jm990614ib00005\/jm990614ib00005_1","first-page":"1251","volume":"90","author":"Keung W. M.","year":"1993","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"jm990614ib00006\/jm990614ib00006_1","first-page":"381","volume":"71","author":"Keung W. M.","year":"1994","journal-title":"EXS"},{"key":"jm990614ib00007\/jm990614ib00007_1","doi-asserted-by":"crossref","first-page":"8993","DOI":"10.1073\/pnas.92.19.8990","volume":"92","author":"Keung W. M.","year":"1995","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"jm990614ib00008\/jm990614ib00008_1","first-page":"4456","volume":"35","author":"Klyosov A. A.","year":"1996","journal-title":"Biochemistry"},{"key":"jm990614ib00009\/jm990614ib00009_1","first-page":"1004","volume":"255","author":"Hald J.","year":"1948","journal-title":"Lancet"},{"key":"jm990614ib00010\/jm990614ib00010_1","doi-asserted-by":"crossref","first-page":"2203","DOI":"10.1073\/pnas.95.5.2198","volume":"95","author":"Keung W. M.","year":"1998","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"jm990614ib00011\/jm990614ib00011_1","first-page":"83","volume":"16","author":"W\u00e4h\u00e4l\u00e4 K.","year":"1989","journal-title":"Finn. Chem. Lett."},{"key":"jm990614ib00012\/jm990614ib00012_1","first-page":"429","volume":"428","author":"Benedict D. R.","year":"1979","journal-title":"Synthesis"},{"key":"jm990614ib00013\/jm990614ib00013_1","first-page":"2173","volume":"35","author":"Johnstone R. A. W.","year":"1979","journal-title":"Tetrahedron"},{"key":"jm990614ib00014\/jm990614ib00014_1","first-page":"3275","volume":"30","author":"Tank A. W.","year":"1981","journal-title":"Biochem. Pharmacol."},{"key":"jm990614ib00015\/jm990614ib00015_1","doi-asserted-by":"crossref","first-page":"13018","DOI":"10.1016\/S0021-9258(18)98796-X","volume":"266","author":"Ambroziak W.","year":"1991","journal-title":"J. Biol. Chem."},{"key":"jm990614ib00016\/jm990614ib00016_1","first-page":"191","volume":"4","author":"Feldstein A.","year":"1961","journal-title":"Life Sci."},{"key":"jm990614ib00017\/jm990614ib00017_1","first-page":"159","volume-title":"The Biology of Alcoholism","author":"Feldstein A.","year":"1971"},{"key":"jm990614ib00018\/jm990614ib00018_1","doi-asserted-by":"crossref","first-page":"820","DOI":"10.1038\/191819a0","volume":"191","author":"Arvola A.","year":"1961","journal-title":"Nature (London)"},{"key":"jm990614ib00019\/jm990614ib00019_1","first-page":"60","volume":"4","author":"Li T.-K.","year":"1979","journal-title":"Drug Alcohol Depend."},{"key":"jm990614ib00020\/jm990614ib00020_1","first-page":"58","volume":"72","author":"von Knorring A.-L.","year":"1985","journal-title":"Acta Psychiatr. Scand."},{"key":"jm990614ib00021\/jm990614ib00021_1","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1016\/S0140-6736(82)92722-2","volume":"2","author":"Harada S.","year":"1982","journal-title":"Lancet"},{"key":"jm990614ib00022\/jm990614ib00022_1","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1146\/annurev.pa.20.040180.000415","volume":"20","author":"Deitrich R. A.","year":"1980","journal-title":"Annu. Rev. Pharmacol."},{"key":"jm990614ib00023\/jm990614ib00023_1","doi-asserted-by":"crossref","first-page":"1572","DOI":"10.1111\/j.1471-4159.1987.tb05702.x","volume":"48","author":"Nilsson G. E.","year":"1987","journal-title":"J. Neurochem."},{"key":"jm990614ib00025\/jm990614ib00025_1","unstructured":"Alivisatos, S. G. A.; Tabakoff, B. Formation and metabolism of \u201cbiogenic\u201d aldehydes. InChemical Modulation of Brain Function; Sabelli, H., Ed.; Raven Press: New York, 1973; pp 41\u221266."}],"container-title":["Journal of Medicinal Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/jm990614i","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,3,24]],"date-time":"2023-03-24T06:43:17Z","timestamp":1679640197000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/jm990614i"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2000,10,6]]},"references-count":24,"journal-issue":{"issue":"22","published-print":{"date-parts":[[2000,11,1]]}},"alternative-id":["10.1021\/jm990614i"],"URL":"https:\/\/doi.org\/10.1021\/jm990614i","relation":{},"ISSN":["0022-2623","1520-4804"],"issn-type":[{"value":"0022-2623","type":"print"},{"value":"1520-4804","type":"electronic"}],"subject":[],"published":{"date-parts":[[2000,10,6]]}}}