{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T19:51:05Z","timestamp":1791402665902,"version":"4.3.3"},"reference-count":35,"publisher":"American Chemical Society (ACS)","issue":"23","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Org. Chem."],"published-print":{"date-parts":[[2011,12,2]]},"DOI":"10.1021\/jo201212p","type":"journal-article","created":{"date-parts":[[2011,10,26]],"date-time":"2011-10-26T21:12:10Z","timestamp":1319663530000},"page":"9630-9640","source":"Crossref","is-referenced-by-count":79,"title":["ReactNMR and ReactIR as Reaction Monitoring and Mechanistic Elucidation Tools: The NCS Mediated Cascade Reaction of \u03b1-Thioamides to \u03b1-Thio-\u03b2-chloroacrylamides"],"prefix":"10.1021","volume":"76","author":[{"given":"David A.","family":"Foley","sequence":"first","affiliation":[{"name":"Analytical\rSciences Research and Development and \u2021Chemical Product Research and Development, Eli Lilly and Company, Lilly Corporate Center, Indianapolis, Indiana\r46285, United States"},{"name":"Department\rof Chemistry and \u2225School of Pharmacy, Analytical and Biological Chemistry\rResearch Facility, University College Cork, Cork, Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher W.","family":"Doecke","sequence":"additional","affiliation":[{"name":"Analytical\rSciences Research and Development and \u2021Chemical Product Research and Development, Eli Lilly and Company, Lilly Corporate Center, Indianapolis, Indiana\r46285, United States"},{"name":"Department\rof Chemistry and \u2225School of Pharmacy, Analytical and Biological Chemistry\rResearch Facility, University College Cork, Cork, Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonas Y.","family":"Buser","sequence":"additional","affiliation":[{"name":"Analytical\rSciences Research and Development and \u2021Chemical Product Research and Development, Eli Lilly and Company, Lilly Corporate Center, Indianapolis, Indiana\r46285, United States"},{"name":"Department\rof Chemistry and \u2225School of Pharmacy, Analytical and Biological Chemistry\rResearch Facility, University College Cork, Cork, Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeremy M.","family":"Merritt","sequence":"additional","affiliation":[{"name":"Analytical\rSciences Research and Development and \u2021Chemical Product Research and Development, Eli Lilly and Company, Lilly Corporate Center, Indianapolis, Indiana\r46285, United States"},{"name":"Department\rof Chemistry and \u2225School of Pharmacy, Analytical and Biological Chemistry\rResearch Facility, University College Cork, Cork, Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Linda","family":"Murphy","sequence":"additional","affiliation":[{"name":"Analytical\rSciences Research and Development and \u2021Chemical Product Research and Development, Eli Lilly and Company, Lilly Corporate Center, Indianapolis, Indiana\r46285, United States"},{"name":"Department\rof Chemistry and \u2225School of Pharmacy, Analytical and Biological Chemistry\rResearch Facility, University College Cork, Cork, Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie","family":"Kissane","sequence":"additional","affiliation":[{"name":"Analytical\rSciences Research and Development and \u2021Chemical Product Research and Development, Eli Lilly and Company, Lilly Corporate Center, Indianapolis, Indiana\r46285, United States"},{"name":"Department\rof Chemistry and \u2225School of Pharmacy, Analytical and Biological Chemistry\rResearch Facility, University College Cork, Cork, Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stuart G.","family":"Collins","sequence":"additional","affiliation":[{"name":"Analytical\rSciences Research and Development and \u2021Chemical Product Research and Development, Eli Lilly and Company, Lilly Corporate Center, Indianapolis, Indiana\r46285, United States"},{"name":"Department\rof Chemistry and \u2225School of Pharmacy, Analytical and Biological Chemistry\rResearch Facility, University College Cork, Cork, Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anita R.","family":"Maguire","sequence":"additional","affiliation":[{"name":"Analytical\rSciences Research and Development and \u2021Chemical Product Research and Development, Eli Lilly and Company, Lilly Corporate Center, Indianapolis, Indiana\r46285, United States"},{"name":"Department\rof Chemistry and \u2225School of Pharmacy, Analytical and Biological Chemistry\rResearch Facility, University College Cork, Cork, Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas","family":"Kaerner","sequence":"additional","affiliation":[{"name":"Analytical\rSciences Research and Development and \u2021Chemical Product Research and Development, Eli Lilly and Company, Lilly Corporate Center, Indianapolis, Indiana\r46285, United States"},{"name":"Department\rof Chemistry and \u2225School of Pharmacy, Analytical and Biological Chemistry\rResearch Facility, University College Cork, Cork, Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2011,11,10]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1006\/jmra.1995.0759","volume":"117","author":"Smallcombe S. H.","year":"1995","journal-title":"J. Magn. Reson., Ser. A"},{"key":"ref2\/cit2","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/j.pnmrs.2010.01.001","volume":"56","author":"Zheng G.","year":"2010","journal-title":"Prog. Nucl. Magn. Reson. Spectrosc."},{"key":"ref3\/cit3","first-page":"11","volume":"19","author":"Bernstein M. A.","year":"2007","journal-title":"Spectrosc. Eur."},{"key":"ref4\/cit4","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1021\/op900305v","volume":"14","author":"Carter C. F.","year":"2010","journal-title":"Org. Process Res. Dev."},{"key":"ref5\/cit5","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0066-4103(07)62001-8","volume":"62","author":"Keifer P. A.","year":"2007","journal-title":"Annu. Rep. NMR Spectrosc."},{"key":"ref6\/cit6","doi-asserted-by":"crossref","first-page":"1954","DOI":"10.1021\/ac026389l","volume":"75","author":"Leo G. C.","year":"2003","journal-title":"Anal. Chem."},{"key":"ref7\/cit7","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1016\/S1367-5931(03)00051-6","volume":"7","author":"Keifer P. A.","year":"2003","journal-title":"Curr. Opin. Chem. Biol."},{"key":"ref8\/cit8","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1021\/ar50127a004","volume":"11","author":"Fyfe C. A.","year":"1978","journal-title":"Acc. Chem. Res."},{"key":"ref9\/cit9","doi-asserted-by":"crossref","first-page":"1111","DOI":"10.1007\/s00216-002-1723-y","volume":"375","author":"Maiwald M.","year":"2003","journal-title":"Anal. Bioanal. Chem."},{"key":"ref10\/cit10","doi-asserted-by":"crossref","first-page":"4514","DOI":"10.1039\/b924936b","volume":"46","author":"Gomez M. V.","year":"2010","journal-title":"Chem. Commun."},{"key":"ref11\/cit11","doi-asserted-by":"crossref","first-page":"953","DOI":"10.1021\/ol049979+","volume":"6","author":"Hoye T. R.","year":"2004","journal-title":"Org. Lett."},{"key":"ref12\/cit12","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1002\/mrc.2401","volume":"47","author":"Chan S. J.","year":"2009","journal-title":"Magn. Reson. Chem."},{"key":"ref13\/cit13","doi-asserted-by":"crossref","first-page":"2861","DOI":"10.1039\/B208387F","author":"Csihony S.","year":"2002","journal-title":"J. Chem. Soc., Perkin Trans. 1"},{"key":"ref14\/cit14","doi-asserted-by":"crossref","first-page":"7437","DOI":"10.1016\/j.tet.2008.05.018","volume":"64","author":"Sicre C.","year":"2008","journal-title":"Tetrahedron"},{"key":"ref15\/cit15","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/S0167-7799(00)01425-6","volume":"18","author":"Brecker L.","year":"2000","journal-title":"Trends Biotechnol."},{"key":"ref16\/cit16","first-page":"572","volume":"11","author":"Weber H.","year":"2000","journal-title":"Curr. Opin. Chem. Biol."},{"key":"ref17\/cit17","doi-asserted-by":"crossref","first-page":"956","DOI":"10.1021\/ja00498a026","volume":"101","author":"Fyfe C. A.","year":"1979","journal-title":"J. Am. Chem. Soc."},{"key":"ref18\/cit18","doi-asserted-by":"crossref","first-page":"951","DOI":"10.1021\/ja00498a025","volume":"101","author":"Fyfe C. A.","year":"1979","journal-title":"J. Am. Chem. Soc."},{"key":"ref19\/cit19","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1021\/op100335q","volume":"15","author":"Barrios Sosa A. C.","year":"2011","journal-title":"Org. Process Res. Dev."},{"key":"ref20\/cit20","doi-asserted-by":"crossref","first-page":"3034","DOI":"10.1039\/b803074j","author":"Gasparini G.","year":"2008","journal-title":"Chem. Commun."},{"key":"ref21\/cit21","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1021\/ol902532f","volume":"12","author":"Herrera A.","year":"2010","journal-title":"Org. Lett."},{"key":"ref22\/cit22a","doi-asserted-by":"crossref","first-page":"6274","DOI":"10.1002\/anie.200902387","volume":"48","author":"Herrera A.","year":"2009","journal-title":"Angew. Chem., Int. Ed."},{"key":"ref23\/cit23","doi-asserted-by":"crossref","first-page":"2102","DOI":"10.1021\/ac100110m","volume":"82","author":"Khajeh M.","year":"2010","journal-title":"Anal. Chem."},{"key":"ref24\/cit24","doi-asserted-by":"crossref","first-page":"1252","DOI":"10.1039\/b820813a","author":"Nilsson M.","year":"2009","journal-title":"Chem. Commun."},{"key":"ref25\/cit25","doi-asserted-by":"crossref","first-page":"13722","DOI":"10.1021\/ja904304h","volume":"131","author":"Xu S.","year":"2009","journal-title":"J. Am. Chem. Soc."},{"key":"ref26\/cit26","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1002\/mrc.1270170114","volume":"17","author":"McGarrity J. F.","year":"1981","journal-title":"Org. Magn. Reson."},{"key":"ref27\/cit27","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1021\/om900919f","volume":"29","author":"Mix A.","year":"2010","journal-title":"Organometallics"},{"key":"ref28\/cit28","doi-asserted-by":"crossref","first-page":"11461","DOI":"10.1021\/ja105107y","volume":"132","author":"Christianson M. D.","year":"2010","journal-title":"J. Am. Chem. Soc."},{"key":"ref29\/cit29","doi-asserted-by":"crossref","first-page":"965","DOI":"10.1002\/cite.200403389","volume":"76","author":"Maiwald M.","year":"2004","journal-title":"Chem. Ing. Tech."},{"key":"ref30\/cit30","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/j.jmr.2003.09.003","volume":"166","author":"Maiwald M.","year":"2004","journal-title":"J. Magn. Reson."},{"key":"ref31\/cit31","doi-asserted-by":"crossref","first-page":"564","DOI":"10.1002\/mrc.2007","volume":"45","author":"Bernstein M. A.","year":"2007","journal-title":"Magn. Reson. Chem."},{"key":"ref32\/cit32","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1016\/0040-4039(94)02288-M","volume":"36","author":"Maguire A. R.","year":"1995","journal-title":"Tetrahedron Lett."},{"key":"ref33\/cit33","doi-asserted-by":"crossref","first-page":"1228","DOI":"10.1039\/B618540A","volume":"5","author":"Murphy M.","year":"2007","journal-title":"Org. Biomol. Chem."},{"key":"ref34\/cit34","doi-asserted-by":"crossref","first-page":"7856","DOI":"10.1021\/jo961438d","volume":"61","author":"Liu Y.","year":"1996","journal-title":"J. Org. Chem."},{"key":"ref35\/cit35","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1021\/jo00838a009","volume":"34","author":"Tuleen D. L.","year":"1969","journal-title":"J. Org. Chem."}],"container-title":["The Journal of Organic Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/jo201212p","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,4]],"date-time":"2023-04-04T12:18:08Z","timestamp":1680610688000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/jo201212p"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,11,10]]},"references-count":35,"journal-issue":{"issue":"23","published-print":{"date-parts":[[2011,12,2]]}},"alternative-id":["10.1021\/jo201212p"],"URL":"https:\/\/doi.org\/10.1021\/jo201212p","relation":{},"ISSN":["0022-3263","1520-6904"],"issn-type":[{"value":"0022-3263","type":"print"},{"value":"1520-6904","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,11,10]]}}}