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Chem."},{"key":"ref21\/cit21","unstructured":"MS3\u00c5 are much more effective dessicants for CH3CN than MS4\u00c5 or any commonly used dessicant apart from P2O5:"},{"key":"ref21\/cit21a","first-page":"23","volume":"28","author":"Burfield D. R.","year":"1977","journal-title":"J. Appl. Chem. Biotechnol."},{"key":"ref21\/cit21b","doi-asserted-by":"crossref","first-page":"3060","DOI":"10.1021\/jo00438a024","volume":"42","author":"Burfield D. R.","year":"1977","journal-title":"J. Org. Chem."},{"key":"ref22\/cit22","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1007\/s11030-005-4386-8","volume":"9","author":"Srinivasan N.","year":"2005","journal-title":"Mol. Diversity"},{"key":"ref23\/cit23","unstructured":"Either in salt form or as the free bases, generated by the addition of excess DIEA, these nitrones were significantly more stable than their unsubstituted counterpart formed from formaldehyde, with no significant changes in their1H NMR spectra observed after 6 days at room temperature."},{"key":"ref24\/cit24","unstructured":"When Oppolzer\u2019s(4b, 4c)conditions, or conditions previously discussed in this report (see Table1) for the preparation oftrans-3a, were employed, the Michael adduct7awas always obtained as the major product. This is likely due to the reduced reactivity of benzaldehyde and cyclohexanecarboxaldehyde compared to formaldehyde."},{"key":"ref25\/cit25","doi-asserted-by":"crossref","first-page":"5481","DOI":"10.1016\/S0040-4039(00)96759-5","volume":"28","author":"Tufariello J. J.","year":"1987","journal-title":"Tetrahedron Lett."},{"key":"ref26\/cit26","unstructured":"In the cycloaddition of anN-(3-oxo-4-pentenyl) nitrone, Grigg et al.(4o)observed an increase in regioselectivity from 1:1 in cyclohexane to 8:1 in DMSO and attributed this to the larger dipole moment of the preferred transition state."},{"key":"ref27\/cit27","unstructured":"For examples of reversible intramolecular nitrone cycloadditions, see:"},{"key":"ref27\/cit27a","doi-asserted-by":"crossref","first-page":"1258","DOI":"10.1039\/b402307b","volume":"2","author":"Horsley H. T.","year":"2004","journal-title":"Org. Biomol. Chem."},{"key":"ref27\/cit27b","doi-asserted-by":"crossref","first-page":"1598","DOI":"10.1021\/jo035639a","volume":"69","author":"Stockman R. A.","year":"2004","journal-title":"J. Org. Chem."},{"key":"ref27\/cit27c","doi-asserted-by":"crossref","first-page":"2435","DOI":"10.1021\/ja00503a033","volume":"101","author":"Tufariello J. J.","year":"1979","journal-title":"J. Am. 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Sci."},{"key":"ref30\/cit30","unstructured":"In reductions where the HCl salt of the isoxazolidine was used (see Table5), the isoxazolidine was first dissolved in a solution of 36% HCl (3.47 mL mmol\u22121) in EtOH (17.4 mL mmol\u22121), and excess HCl and EtOH were then removed under reduced pressure."}],"container-title":["The Journal of Organic Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/jo8018285","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,3,9]],"date-time":"2023-03-09T11:45:16Z","timestamp":1678362316000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/jo8018285"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,11,24]]},"references-count":102,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2009,1,2]]}},"alternative-id":["10.1021\/jo8018285"],"URL":"https:\/\/doi.org\/10.1021\/jo8018285","relation":{},"ISSN":["0022-3263","1520-6904"],"issn-type":[{"type":"print","value":"0022-3263"},{"type":"electronic","value":"1520-6904"}],"subject":[],"published":{"date-parts":[[2008,11,24]]}}}