{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,28]],"date-time":"2025-09-28T20:25:36Z","timestamp":1759091136376},"reference-count":17,"publisher":"American Geophysical Union (AGU)","issue":"3","license":[{"start":{"date-parts":[[1998,3,1]],"date-time":"1998-03-01T00:00:00Z","timestamp":888710400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Pharmaceutical Sciences"],"published-print":{"date-parts":[[1998,3]]},"DOI":"10.1021\/js970173v","type":"journal-article","created":{"date-parts":[[2002,8,25]],"date-time":"2002-08-25T09:40:54Z","timestamp":1030268454000},"page":"379-386","source":"Crossref","is-referenced-by-count":9,"title":["Determination of Binding Conformations of Drugs to Human Serum Albumin by Transferred Nuclear Overhauser Effect Measurements and Conformational Analyses Using High-Temperature Molecular Dynamics Calculations"],"prefix":"10.1029","volume":"87","author":[{"given":"Yasuo","family":"Matsushita","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroaki","family":"Gouda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hideki","family":"Tsujishita","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shuichi","family":"Hirono","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"13","reference":[{"key":"10.1021\/js970173v_bb0005","first-page":"824","volume":"11","author":"Sudlow","year":"1975","journal-title":"Mol. Pharmacol."},{"key":"10.1021\/js970173v_bb0010","first-page":"1052","volume":"12","author":"Sudlow","year":"1976","journal-title":"Mol Pharmacol."},{"key":"10.1021\/js970173v_bb0015","first-page":"767","volume":"16","author":"Sjoholm","year":"1979","journal-title":"Mol. Pharmacol."},{"key":"10.1021\/js970173v_bb0020","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1038\/358209a0","volume":"358","author":"He","year":"1992","journal-title":"Nature"},{"key":"10.1021\/js970173v_bb0025","unstructured":"Tsujishita, H.; Hirono, S. J. Comput.-Aided Molecular Design 1997, 10 (3), in press."},{"key":"10.1021\/js970173v_bb0030","doi-asserted-by":"crossref","first-page":"604","DOI":"10.1006\/jmbi.1995.0322","volume":"249","author":"Abseher","year":"1972","journal-title":"Mol. Biol."},{"key":"10.1021\/js970173v_bb0035","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/0141-8130(79)90008-4","volume":"1","author":"Albrand","year":"1979","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1021\/js970173v_bb0040","first-page":"4546","volume":"71","author":"Jeener","year":"1979","journal-title":"Chem. Phys."},{"key":"10.1021\/js970173v_bb0045","first-page":"423","volume":"53","author":"Clore","year":"1983","journal-title":"Magn. Reson."},{"key":"10.1021\/js970173v_bb0050","first-page":"77","volume":"93","author":"Campbell","year":"1991","journal-title":"Magn. Reson."},{"key":"10.1021\/js970173v_bb0055","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1146\/annurev.bb.22.060193.000531","volume":"22","author":"Campbell","year":"1993","journal-title":"Annu. Rev. Biophys. Biomol. Struct."},{"key":"10.1021\/js970173v_bb0060","doi-asserted-by":"crossref","first-page":"8780","DOI":"10.1021\/bi00027a029","volume":"34","author":"Jakoby","year":"1995","journal-title":"Biochemistry"},{"key":"10.1021\/js970173v_bb0065","doi-asserted-by":"crossref","first-page":"8127","DOI":"10.1021\/ja00467a001","volume":"99","author":"Allinger","year":"1977","journal-title":"Am. Chem. Soc."},{"key":"10.1021\/js970173v_bb0070","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/0263-7855(88)80054-7","volume":"6","author":"Ferrin","year":"1988","journal-title":"Mol. Graphics"},{"key":"10.1021\/js970173v_bb0075","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1002\/jps.2600710225","volume":"71","author":"Abd Elbary","year":"1982","journal-title":"Pharm. Sci."},{"key":"10.1021\/js970173v_bb0080","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/S0021-9673(00)91155-5","volume":"167","author":"Sebille","year":"1978","journal-title":"Chromator."},{"key":"10.1021\/js970173v_bb0085","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1248\/bpb1978.3.667","volume":"3","author":"Goto","year":"1980","journal-title":"Pharm. Dynam."}],"container-title":["Journal of Pharmaceutical Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022354915505212?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022354915505212?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,7,22]],"date-time":"2021-07-22T07:18:23Z","timestamp":1626938303000},"score":1,"resource":{"primary":{"URL":"http:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022354915505212"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1998,3]]},"references-count":17,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1998,3]]}},"alternative-id":["S0022354915505212"],"URL":"https:\/\/doi.org\/10.1021\/js970173v","relation":{},"ISSN":["0022-3549"],"issn-type":[{"value":"0022-3549","type":"print"}],"subject":[],"published":{"date-parts":[[1998,3]]}}}