{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T18:14:45Z","timestamp":1791396885135,"version":"4.3.3"},"reference-count":66,"publisher":"American Chemical Society (ACS)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Langmuir"],"published-print":{"date-parts":[[2010,1,19]]},"DOI":"10.1021\/la902220a","type":"journal-article","created":{"date-parts":[[2009,9,2]],"date-time":"2009-09-02T18:33:30Z","timestamp":1251916410000},"page":"809-814","source":"Crossref","is-referenced-by-count":375,"title":["Semiquantitative Study of the EDC\/NHS Activation of Acid Terminal Groups at Modified Porous Silicon Surfaces"],"prefix":"10.1021","volume":"26","author":[{"given":"S.","family":"Sam","sequence":"first","affiliation":[{"name":"Physique de la Mati\u00e8re Condens\u00e9e, \u00c9cole Polytechnique, CNRS, 91128 Palaiseau, France"},{"name":"UDTS, 2 bd Frantz Fanon, BP 399, Alger-Gare, Algiers, Algeria"},{"name":"Laboratoire d'hydrom\u00e9tallurgie et chimie inorganique mol\u00e9culaire, Facult\u00e9 de Chimie, USTHB, BP 32 El Alia, 16111 Bab-Ezzouar, Algiers, Algeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"Touahir","sequence":"additional","affiliation":[{"name":"Physique de la Mati\u00e8re Condens\u00e9e, \u00c9cole Polytechnique, CNRS, 91128 Palaiseau, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Salvador Andresa","sequence":"additional","affiliation":[{"name":"Physique de la Mati\u00e8re Condens\u00e9e, \u00c9cole Polytechnique, CNRS, 91128 Palaiseau, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Allongue","sequence":"additional","affiliation":[{"name":"Physique de la Mati\u00e8re Condens\u00e9e, \u00c9cole Polytechnique, CNRS, 91128 Palaiseau, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.-N.","family":"Chazalviel","sequence":"additional","affiliation":[{"name":"Physique de la Mati\u00e8re Condens\u00e9e, \u00c9cole Polytechnique, CNRS, 91128 Palaiseau, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A. C.","family":"Gouget-Laemmel","sequence":"additional","affiliation":[{"name":"Physique de la Mati\u00e8re Condens\u00e9e, \u00c9cole Polytechnique, CNRS, 91128 Palaiseau, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Henry de Villeneuve","sequence":"additional","affiliation":[{"name":"Physique de la Mati\u00e8re Condens\u00e9e, \u00c9cole Polytechnique, CNRS, 91128 Palaiseau, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Moraillon","sequence":"additional","affiliation":[{"name":"Physique de la Mati\u00e8re Condens\u00e9e, \u00c9cole Polytechnique, CNRS, 91128 Palaiseau, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.","family":"Ozanam","sequence":"additional","affiliation":[{"name":"Physique de la Mati\u00e8re Condens\u00e9e, \u00c9cole Polytechnique, CNRS, 91128 Palaiseau, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N.","family":"Gabouze","sequence":"additional","affiliation":[{"name":"UDTS, 2 bd Frantz Fanon, BP 399, Alger-Gare, Algiers, Algeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Djebbar","sequence":"additional","affiliation":[{"name":"Laboratoire d'hydrom\u00e9tallurgie et chimie inorganique mol\u00e9culaire, Facult\u00e9 de Chimie, USTHB, BP 32 El Alia, 16111 Bab-Ezzouar, Algiers, Algeria"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2009,9,2]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1021\/cr0684467","volume":"108","author":"Sassolas A.","year":"2008","journal-title":"Chem. Rev."},{"key":"ref2\/cit2","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1021\/cr068105t","volume":"108","author":"Borisov S. M.","year":"2008","journal-title":"Chem. Rev."},{"key":"ref3\/cit3","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1007\/128_003","volume":"260","author":"Luderer F.","year":"2005","journal-title":"Top. Curr. Chem."},{"key":"ref4\/cit4","doi-asserted-by":"crossref","first-page":"1775","DOI":"10.1021\/bm061197b","volume":"8","author":"Rusmini F.","year":"2007","journal-title":"Biomacromolecules"},{"key":"ref5\/cit5","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1016\/0003-2697(86)90176-4","volume":"156","author":"Staros J. V.","year":"1986","journal-title":"Anal. Biochem."},{"key":"ref6\/cit6","volume-title":"Bioconjugate Techniques","author":"Hermanson G. T.","year":"2008","edition":"2"},{"key":"ref7\/cit7","doi-asserted-by":"crossref","first-page":"5780","DOI":"10.1021\/la0343066","volume":"19","author":"Dordi B.","year":"2003","journal-title":"Langmuir"},{"key":"ref8\/cit8","doi-asserted-by":"crossref","first-page":"2107","DOI":"10.1021\/la8026946","volume":"25","author":"Taratula O.","year":"2009","journal-title":"Langmuir"},{"key":"ref9\/cit9","doi-asserted-by":"crossref","first-page":"6081","DOI":"10.1021\/la015597q","volume":"18","author":"Wojtyk J. T. C.","year":"2002","journal-title":"Langmuir"},{"key":"ref10\/cit10a","doi-asserted-by":"crossref","first-page":"9235","DOI":"10.1021\/la048474p","volume":"20","author":"B\u00f6cking T.","year":"2004","journal-title":"Langmuir"},{"key":"ref10\/cit10b","doi-asserted-by":"crossref","first-page":"7931","DOI":"10.1021\/la800462u","volume":"24","author":"Yang M.","year":"2008","journal-title":"Langmuir"},{"key":"ref11\/cit11a","doi-asserted-by":"crossref","first-page":"6485","DOI":"10.1021\/la970933h","volume":"13","author":"Patel N.","year":"1997","journal-title":"Langmuir"},{"key":"ref11\/cit11b","doi-asserted-by":"crossref","first-page":"17453","DOI":"10.1021\/ja056422w","volume":"127","author":"Wolf L. K.","year":"2005","journal-title":"J. Am. Chem. Soc."},{"key":"ref11\/cit11c","doi-asserted-by":"crossref","first-page":"1422","DOI":"10.1016\/j.bios.2004.04.017","volume":"20","author":"Lee J. W.","year":"2005","journal-title":"Biosens. Bioelectron."},{"key":"ref11\/cit11d","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1007\/s10544-007-9126-7","volume":"10","author":"Jang L.-S.","year":"2008","journal-title":"Biomed. Microdevices"},{"key":"ref12\/cit12a","doi-asserted-by":"crossref","first-page":"133","DOI":"10.2116\/analsci.9.133","volume":"9","author":"Nakano K.","year":"1993","journal-title":"Anal. Sci."},{"key":"ref12\/cit12b","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/0014-5793(94)01296-2","volume":"356","author":"Wagner P.","year":"1994","journal-title":"FEBS Lett."},{"key":"ref13\/cit13","doi-asserted-by":"crossref","first-page":"3145","DOI":"10.1021\/ja00116a019","volume":"117","author":"Linford M. R.","year":"1995","journal-title":"J. Am. Chem. Soc."},{"key":"ref14\/cit14a","doi-asserted-by":"crossref","first-page":"1271","DOI":"10.1021\/cr000064s","volume":"102","author":"Buriak J. M.","year":"2002","journal-title":"Chem. Rev."},{"key":"ref14\/cit14b","first-page":"23","volume":"2","author":"Wayner D. D. M.","year":"2002","journal-title":"J. Chem. Soc., Perkin Trans. 2"},{"key":"ref14\/cit14c","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1016\/j.cossms.2006.03.006","volume":"9","author":"Boukherroub R.","year":"2005","journal-title":"Curr. Opin. Solid State Mater. Sci."},{"key":"ref14\/cit14d","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1002\/tcr.20041","volume":"5","author":"Shirahata N.","year":"2005","journal-title":"Chem. Rec."},{"key":"ref15\/cit15","doi-asserted-by":"crossref","first-page":"2289","DOI":"10.1063\/1.1593223","volume":"94","author":"Lehner A.","year":"2003","journal-title":"J. Appl. Phys."},{"key":"ref16\/cit16a","doi-asserted-by":"crossref","first-page":"10630","DOI":"10.1021\/la047913h","volume":"20","author":"Bunimovich Y. L.","year":"2004","journal-title":"Langmuir"},{"key":"ref16\/cit16b","doi-asserted-by":"crossref","first-page":"1868","DOI":"10.1088\/0957-4484\/16\/9\/075","volume":"16","author":"Streifer J. A.","year":"2005","journal-title":"Nanotechnology"},{"key":"ref16\/cit16c","doi-asserted-by":"crossref","first-page":"K81","DOI":"10.1149\/1.2937178","volume":"11","author":"Scheibal Z. R.","year":"2008","journal-title":"Electrochem. Solid-State Lett."},{"key":"ref17\/cit17","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1006\/jsbi.1997.3881","volume":"119","author":"Wagner P.","year":"1997","journal-title":"J. Struct. Biol."},{"key":"ref18\/cit18a","doi-asserted-by":"crossref","first-page":"1205","DOI":"10.1021\/ja9936161","volume":"122","author":"Strother T.","year":"2000","journal-title":"J. Am. Chem. Soc."},{"key":"ref18\/cit18b","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1002\/1521-3773(20020215)41:4<615::AID-ANIE615>3.0.CO;2-Y","volume":"41","author":"Pike A. R.","year":"2002","journal-title":"Angew. Chem., Int. Ed."},{"key":"ref18\/cit18c","doi-asserted-by":"crossref","first-page":"20620","DOI":"10.1021\/jp0535689","volume":"109","author":"Guo D.-J.","year":"2005","journal-title":"J. Phys. Chem. B"},{"key":"ref18\/cit18d","doi-asserted-by":"crossref","first-page":"10522","DOI":"10.1021\/la051191s","volume":"21","author":"B\u00f6cking T.","year":"2005","journal-title":"Langmuir"},{"key":"ref19\/cit19","doi-asserted-by":"crossref","first-page":"11713","DOI":"10.1021\/la047886v","volume":"20","author":"Voicu R.","year":"2004","journal-title":"Langmuir"},{"key":"ref20\/cit20a","doi-asserted-by":"crossref","first-page":"7821","DOI":"10.1021\/ja011116d","volume":"123","author":"Stewart M. P.","year":"2001","journal-title":"J. Am. Chem. Soc."},{"key":"ref20\/cit20b","doi-asserted-by":"crossref","first-page":"1352","DOI":"10.1002\/anie.200352137","volume":"43","author":"Sun Q.-Y.","year":"2004","journal-title":"Angew. Chem., Int. Ed."},{"key":"ref20\/cit20c","doi-asserted-by":"crossref","first-page":"4906","DOI":"10.1039\/b511535c","volume":"15","author":"Liu Y.","year":"2005","journal-title":"J. Mater. Chem."},{"key":"ref21\/cit21a","doi-asserted-by":"crossref","first-page":"2172","DOI":"10.1021\/la001494g","volume":"17","author":"Sieval A. B.","year":"2001","journal-title":"Langmuir"},{"key":"ref21\/cit21b","doi-asserted-by":"crossref","first-page":"6275","DOI":"10.1021\/la0106337","volume":"17","author":"Zhang L.","year":"2001","journal-title":"Langmuir"},{"key":"ref22\/cit22","doi-asserted-by":"crossref","first-page":"5688","DOI":"10.1021\/la9911990","volume":"16","author":"Cicero R. L.","year":"2000","journal-title":"Langmuir"},{"key":"ref23\/cit23","doi-asserted-by":"crossref","first-page":"7158","DOI":"10.1021\/jp7119922","volume":"112","author":"Moraillon A.","year":"2008","journal-title":"J. Phys. Chem. C"},{"key":"ref24\/cit24a","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1021\/ac980959t","volume":"71","author":"Lahiri J.","year":"1999","journal-title":"Anal. Chem."},{"key":"ref24\/cit24b","doi-asserted-by":"crossref","first-page":"4669","DOI":"10.1021\/la046819y","volume":"21","author":"Chi Y. S.","year":"2005","journal-title":"Langmuir"},{"key":"ref24\/cit24c","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1016\/j.colsurfb.2006.09.010","volume":"53","author":"Briand E.","year":"2006","journal-title":"Colloids Surf., B"},{"key":"ref25\/cit25","doi-asserted-by":"crossref","first-page":"1157","DOI":"10.1016\/S0956-5663(03)00002-2","volume":"18","author":"Wei F.","year":"2003","journal-title":"Biosens. Bioelectron."},{"key":"ref26\/cit26","doi-asserted-by":"crossref","first-page":"977","DOI":"10.1016\/S0956-5663(97)00053-5","volume":"12","author":"Mirsky V. M.","year":"1997","journal-title":"Biosens. Bioelectron."},{"key":"ref27\/cit27","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1016\/S0956-5663(03)00274-4","volume":"19","author":"Grubor N. M.","year":"2004","journal-title":"Biosens. Bioelectron."},{"key":"ref28\/cit28","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1006\/abio.1994.1144","volume":"218","author":"Seghal D.","year":"1994","journal-title":"Anal. Biochem."},{"key":"ref29\/cit29","doi-asserted-by":"crossref","first-page":"H59","DOI":"10.1149\/1.1432679","volume":"149","author":"Boukherroub R.","year":"2002","journal-title":"J. Electrochem. Soc."},{"key":"ref30\/cit30","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1021\/la052145v","volume":"22","author":"Faucheux A.","year":"2006","journal-title":"Langmuir"},{"key":"ref31\/cit31","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1149\/1.2043865","volume":"142","author":"Ogata Y.","year":"1995","journal-title":"J. Electrochem. Soc."},{"key":"ref32\/cit32","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0039-6028(96)80111-7","volume":"365","author":"da Fonseca C.","year":"1995","journal-title":"Surf. Sci."},{"key":"ref33\/cit33a","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1016\/0038-1098(79)90666-5","volume":"29","author":"Lucovsky G.","year":"1979","journal-title":"Solid State Commun."},{"key":"ref33\/cit33b","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1016\/0038-1098(84)90156-X","volume":"50","author":"Ubara H.","year":"1984","journal-title":"Solid State Commun."},{"key":"ref33\/cit33c","unstructured":"cChazalviel, J.N. and Ozanam, F.InEMIS Datarev.,Ser. 18 (Properties of Porous Silicon);Canham, L., Ed.The Institution of Electrical Engineers:London, 1997; pp59\u221265."},{"key":"ref34\/cit34a","doi-asserted-by":"crossref","first-page":"6704","DOI":"10.1021\/la970762g","volume":"13","author":"Yan L.","year":"1997","journal-title":"Langmuir"},{"key":"ref34\/cit34b","doi-asserted-by":"crossref","first-page":"1326","DOI":"10.1021\/la061260i","volume":"23","author":"Faucheux A.","year":"2007","journal-title":"Langmuir"},{"key":"ref35\/cit35","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1021\/cr60165a001","volume":"53","author":"Khorana H. G.","year":"1953","journal-title":"Chem. Rev."},{"key":"ref36\/cit36","doi-asserted-by":"crossref","first-page":"2447","DOI":"10.1016\/S0021-9258(18)95981-8","volume":"242","author":"Hoare D. G.","year":"1967","journal-title":"J. Biol. Chem."},{"key":"ref37\/cit37","doi-asserted-by":"crossref","first-page":"6506","DOI":"10.1016\/j.tet.2007.03.075","volume":"63","author":"Iwasawa T.","year":"2007","journal-title":"Tetrahedron"},{"key":"ref38\/cit38a","doi-asserted-by":"crossref","first-page":"3187","DOI":"10.1021\/ac9605861","volume":"68","author":"Frey B. L.","year":"1996","journal-title":"Anal. Chem."},{"key":"ref38\/cit38b","doi-asserted-by":"crossref","first-page":"16508","DOI":"10.1021\/jp047726s","volume":"108","author":"Xiao S.-J.","year":"2004","journal-title":"J. Phys. Chem. B"},{"key":"ref39\/cit39","volume-title":"The Handbook of Infrared and Raman Characteristic Frequencies of Organic Molecules","author":"Lin-Vien D.","year":"1991"},{"key":"ref40\/cit40","doi-asserted-by":"crossref","first-page":"9440","DOI":"10.1021\/la801219u","volume":"24","author":"Aureau D.","year":"2008","journal-title":"Langmuir"},{"key":"ref41\/cit41","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1021\/bc00031a015","volume":"6","author":"Nakajima N.","year":"1995","journal-title":"Bioconjugate Chem."},{"key":"ref42\/cit42a","doi-asserted-by":"crossref","first-page":"225108","DOI":"10.1063\/1.2927256","volume":"128","author":"Douarche C.","year":"2008","journal-title":"J. Chem. Phys."},{"key":"ref42\/cit42b","unstructured":"bDouarche, C.PhD Thesis, Universit\u00e9 de Lille 1 (USTL), 2007, ], surface activation was performed by exposing the acid surface to EDC alone (30 min) and then adding NHS (60 min). Applying this procedure here with [EDC] = [NHS] = 5 mM yields an incomplete reaction (\u03b7 = 1.6), consistent with irreversible formation ofN-acylurea during the first step of the procedure."},{"key":"ref43\/cit43","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1149\/1.3120708","volume":"19","author":"Touahir L.","year":"2009","journal-title":"ECS Trans."}],"container-title":["Langmuir"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/la902220a","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,3,15]],"date-time":"2023-03-15T04:49:19Z","timestamp":1678855759000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/la902220a"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,9,2]]},"references-count":66,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2010,1,19]]}},"alternative-id":["10.1021\/la902220a"],"URL":"https:\/\/doi.org\/10.1021\/la902220a","relation":{},"ISSN":["0743-7463","1520-5827"],"issn-type":[{"value":"0743-7463","type":"print"},{"value":"1520-5827","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,9,2]]}}}