{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T08:25:49Z","timestamp":1789979149863,"version":"4.0.1"},"reference-count":40,"publisher":"American Chemical Society (ACS)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Mol. Pharmaceutics"],"published-print":{"date-parts":[[2005,6,1]]},"DOI":"10.1021\/mp050012x","type":"journal-article","created":{"date-parts":[[2005,6,6]],"date-time":"2005-06-06T04:28:06Z","timestamp":1118032086000},"page":"206-217","source":"Crossref","is-referenced-by-count":34,"title":["Biodistribution and Hepatic Uptake of Triplex-Forming Oligonucleotides against Type \u03b11(I) Collagen Gene Promoter in Normal and Fibrotic Rats"],"prefix":"10.1021","volume":"2","author":[{"given":"Kun","family":"Cheng","sequence":"first","affiliation":[{"name":"Departments of Pharmaceutical and Molecular Sciences, University of Tennessee Health Science Center, Memphis, Tennessee 38163"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhaoyang","family":"Ye","sequence":"additional","affiliation":[{"name":"Departments of Pharmaceutical and Molecular Sciences, University of Tennessee Health Science Center, Memphis, Tennessee 38163"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ramareddy V.","family":"Guntaka","sequence":"additional","affiliation":[{"name":"Departments of Pharmaceutical and Molecular Sciences, University of Tennessee Health Science Center, Memphis, Tennessee 38163"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ram I.","family":"Mahato","sequence":"additional","affiliation":[{"name":"Departments of Pharmaceutical and Molecular Sciences, University of Tennessee Health Science Center, Memphis, Tennessee 38163"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2005,5,10]]},"reference":[{"key":"mp050012xb00001\/mp050012xb00001_1","first-page":"760","volume":"124","author":"Brenner D. A.","year":"1994","journal-title":"J. Lab. Clin. Med."},{"key":"mp050012xb00002\/mp050012xb00002_1","doi-asserted-by":"crossref","first-page":"2188","DOI":"10.1093\/nar\/25.11.2182","volume":"25","author":"Joseph J.","year":"1997","journal-title":"Nucleic Acids Res."},{"key":"mp050012xb00003\/mp050012xb00003_1","doi-asserted-by":"crossref","first-page":"5222","DOI":"10.1093\/nar\/26.22.5218","volume":"26","author":"Nakanishi M.","year":"1998","journal-title":"Nucleic Acids Res."},{"key":"mp050012xb00004\/mp050012xb00004_1","doi-asserted-by":"crossref","first-page":"2250","DOI":"10.1074\/jbc.275.4.2247","volume":"275","author":"Friedman S. L.","year":"2000","journal-title":"J. Biol. Chem."},{"key":"mp050012xb00005\/mp050012xb00005_1","doi-asserted-by":"crossref","first-page":"1221","DOI":"10.1016\/S0016-5085(99)70407-5","volume":"117","author":"Knittel T.","year":"1999","journal-title":"Gastroenterology"},{"key":"mp050012xb00006\/mp050012xb00006_1","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1016\/0006-2952(95)00010-W","volume":"49","author":"Zhang R.","year":"1995","journal-title":"Biochem. Pharmacol."},{"key":"mp050012xb00007\/mp050012xb00007_1","doi-asserted-by":"crossref","first-page":"895","DOI":"10.1016\/S0006-2952(96)00880-5","volume":"53","author":"Mahato R. I.","year":"1997","journal-title":"Biochem. Pharmacol."},{"key":"mp050012xb00008\/mp050012xb00008_1","first-page":"458","volume":"286","author":"Graham M. J.","year":"1998","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"mp050012xb00009\/mp050012xb00009_1","doi-asserted-by":"crossref","first-page":"26377","DOI":"10.1074\/jbc.274.37.26369","volume":"274","author":"Bates P. J.","year":"1999","journal-title":"J. Biol. Chem."},{"key":"mp050012xb00010\/mp050012xb00010_1","first-page":"43230","volume":"276","author":"Xu X.","year":"2001","journal-title":"J. Biol. Chem."},{"key":"mp050012xb00011\/mp050012xb00011_1","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/S0168-8278(87)80570-6","volume":"5","author":"Jezequel A. M.","year":"1987","journal-title":"J. Hepatol."},{"key":"mp050012xb00012\/mp050012xb00012_1","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1016\/S0168-8278(85)80747-9","volume":"1","author":"Jenkins S. A.","year":"1985","journal-title":"J. Hepatol."},{"key":"mp050012xb00013\/mp050012xb00013_1","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/0003-2697(81)90261-X","volume":"112","author":"Jamall I. S.","year":"1981","journal-title":"Anal. Biochem."},{"key":"mp050012xb00014\/mp050012xb00014_1","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/0076-6879(90)90009-P","volume":"190","author":"Hendriks H. F.","year":"1990","journal-title":"Methods Enzymol."},{"key":"mp050012xb00015\/mp050012xb00015_1","doi-asserted-by":"crossref","first-page":"4055","DOI":"10.1073\/pnas.92.9.4051","volume":"92","author":"Burgess T. L.","year":"1995","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"mp050012xb00016\/mp050012xb00016_1","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.taap.2004.04.017","volume":"201","author":"Jason T. L.","year":"2004","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"mp050012xb00017\/mp050012xb00017_1","doi-asserted-by":"crossref","first-page":"21009","DOI":"10.1016\/S0021-9258(17)31921-X","volume":"269","author":"Acton S. L.","year":"1994","journal-title":"J. Biol. Chem."},{"key":"mp050012xb00018\/mp050012xb00018_1","doi-asserted-by":"crossref","first-page":"11039","DOI":"10.1021\/bi00202a024","volume":"33","author":"Laptev A. V.","year":"1994","journal-title":"J. Biochemistry"},{"key":"mp050012xb00019\/mp050012xb00019_1","doi-asserted-by":"crossref","first-page":"18237","DOI":"10.1074\/jbc.M108065200","volume":"277","author":"Stefanovic B.","year":"2002","journal-title":"J. Biol. Chem."},{"key":"mp050012xb00020\/mp050012xb00020_1","doi-asserted-by":"crossref","first-page":"23829","DOI":"10.1074\/jbc.M314060200","volume":"279","author":"Lindquist J. N.","year":"2004","journal-title":"J. Biol. Chem."},{"key":"mp050012xb00021\/mp050012xb00021_1","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1038\/nm828","volume":"9","author":"Song E.","year":"2003","journal-title":"Nat. Med."},{"key":"mp050012xb00022\/mp050012xb00022_1","doi-asserted-by":"crossref","first-page":"7802","DOI":"10.1073\/pnas.1330920100","volume":"100","author":"Zender L.","year":"2003","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"mp050012xb00023\/mp050012xb00023_1","first-page":"59","volume":"93","author":"Yu R. Z.","year":"2004","journal-title":"J. Pharm. Sci."},{"key":"mp050012xb00024\/mp050012xb00024_1","doi-asserted-by":"crossref","first-page":"16","DOI":"10.2165\/00003088-199528010-00002","volume":"28","author":"Agrawal S.","year":"1995","journal-title":"Clin. Pharmacokinet."},{"key":"mp050012xb00025\/mp050012xb00025_1","doi-asserted-by":"crossref","first-page":"3296","DOI":"10.1093\/nar\/25.16.3290","volume":"25","author":"Bijsterbosch M. K.","year":"1997","journal-title":"J. Nucleic Acids Res."},{"key":"mp050012xb00026\/mp050012xb00026_1","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1089\/oli.1.1997.7.71","volume":"7","author":"DeLong R. K.","year":"1997","journal-title":"Antisense Nucleic Acid Drug Dev."},{"key":"mp050012xb00027\/mp050012xb00027_1","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1093\/nar\/20.2.307","volume":"20","author":"Zendegui J. G.","year":"1992","journal-title":"Nucleic Acids Res."},{"key":"mp050012xb00028\/mp050012xb00028_1","first-page":"1281","volume":"25","author":"Geary R. S.","year":"1997","journal-title":"Drug Metab. Dispos."},{"key":"mp050012xb00029\/mp050012xb00029_1","first-page":"725","volume":"149","author":"Rifai A.","year":"1996","journal-title":"Am. J. Pathol."},{"key":"mp050012xb00030\/mp050012xb00030_1","doi-asserted-by":"crossref","first-page":"668","DOI":"10.1016\/S0006-2952(97)00190-1","volume":"54","author":"Phillips J. A.","year":"1997","journal-title":"Biochem. Pharmacol."},{"key":"mp050012xb00031\/mp050012xb00031_1","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1038\/sj.gt.3301647","volume":"9","author":"Garcia-Banuelos J.","year":"2002","journal-title":"Gene Ther."},{"key":"mp050012xb00032\/mp050012xb00032_1","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1016\/S0006-2952(98)00077-X","volume":"56","author":"Steward A.","year":"1998","journal-title":"Biochem. Pharmacol."},{"key":"mp050012xb00033\/mp050012xb00033_1","first-page":"60","volume":"133","author":"Emlen W.","year":"1988","journal-title":"Am. J. Pathol."},{"key":"mp050012xb00034\/mp050012xb00034_1","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1089\/oli.1.1996.6.177","volume":"6","author":"Takakura Y.","year":"1996","journal-title":"Antisense Nucleic Acid Drug Dev."},{"key":"mp050012xb00035\/mp050012xb00035_1","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1124\/jpet.301.2.467","volume":"301","author":"Yamasaki Y.","year":"2002","journal-title":"J Pharmacol. Exp. Ther."},{"key":"mp050012xb00036\/mp050012xb00036_1","first-page":"496","volume":"292","author":"Butler M.","year":"2000","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"mp050012xb00038\/mp050012xb00038_1","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1016\/S0006-2952(01)00705-5","volume":"62","author":"Bijsterbosch M. K.","year":"2001","journal-title":"J. Biochem. Pharmacol."},{"key":"mp050012xb00039\/mp050012xb00039_1","first-page":"4476","volume":"44","author":"Ye Z.","year":"2005","journal-title":"Biochemistry"},{"key":"mp050012xb00040\/mp050012xb00040_1","doi-asserted-by":"crossref","first-page":"7599","DOI":"10.1073\/pnas.88.17.7595","volume":"88","author":"Agrawal S.","year":"1991","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"mp050012xb00041\/mp050012xb00041_1","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1002\/bdd.2510130308","volume":"13","author":"Goodarzi G.","year":"1992","journal-title":"Biopharm. Drug Dispos."}],"container-title":["Molecular Pharmaceutics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/mp050012x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,9,23]],"date-time":"2021-09-23T06:09:51Z","timestamp":1632377391000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/mp050012x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,5,10]]},"references-count":40,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2005,6,1]]}},"alternative-id":["10.1021\/mp050012x"],"URL":"https:\/\/doi.org\/10.1021\/mp050012x","relation":{},"ISSN":["1543-8384","1543-8392"],"issn-type":[{"value":"1543-8384","type":"print"},{"value":"1543-8392","type":"electronic"}],"subject":[],"published":{"date-parts":[[2005,5,10]]}}}