{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,17]],"date-time":"2025-10-17T12:50:11Z","timestamp":1760705411788},"reference-count":39,"publisher":"American Chemical Society (ACS)","issue":"11","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Mol. Pharmaceutics"],"published-print":{"date-parts":[[2012,11,5]]},"DOI":"10.1021\/mp3003539","type":"journal-article","created":{"date-parts":[[2012,9,10]],"date-time":"2012-09-10T04:39:34Z","timestamp":1347251974000},"page":"3318-3329","source":"Crossref","is-referenced-by-count":10,"title":["Enhanced and Selective Killing of Chronic Myelogenous Leukemia Cells with an Engineered BCR-ABL Binding Protein and Imatinib"],"prefix":"10.1021","volume":"9","author":[{"given":"Jonathan E.","family":"Constance","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David W.","family":"Woessner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karina J.","family":"Matissek","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutics and Biopharmacy, Philipps-Universit\u00e4t,\rGermany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohanad","family":"Mossalam","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carol S.","family":"Lim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"316","published-online":{"date-parts":[[2012,10,12]]},"reference":[{"issue":"4","key":"ref1\/cit1","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1016\/j.molcel.2005.06.030","volume":"19","author":"Hantschel O.","year":"2005","journal-title":"Mol. Cell"},{"issue":"2","key":"ref2\/cit2","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1038\/84683","volume":"7","author":"Vigneri P.","year":"2001","journal-title":"Nat. Med."},{"issue":"3","key":"ref3\/cit3","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/j.jconrel.2009.06.026","volume":"140","author":"Dixon A. S.","year":"2009","journal-title":"J. Controlled Release"},{"issue":"6","key":"ref4\/cit4","doi-asserted-by":"crossref","first-page":"804","DOI":"10.1242\/jcs.024653","volume":"121","author":"Qi X.","year":"2008","journal-title":"J. Cell Sci."},{"issue":"20","key":"ref5\/cit5","doi-asserted-by":"crossref","first-page":"17281","DOI":"10.1074\/jbc.M101414200","volume":"276","author":"Kumar S.","year":"2001","journal-title":"J. Biol. Chem."},{"issue":"8","key":"ref6\/cit6","doi-asserted-by":"crossref","first-page":"2317","DOI":"10.1007\/s11095-012-0758-9","volume":"29","author":"Constance J. E.","year":"2012","journal-title":"Pharm. Res."},{"issue":"3","key":"ref7\/cit7","doi-asserted-by":"crossref","first-page":"848","DOI":"10.1016\/j.bbrc.2007.12.029","volume":"366","author":"Gupta M.","year":"2008","journal-title":"Biochem. Biophys. Res. Commun."},{"issue":"6","key":"ref8\/cit8","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1111\/j.1600-0854.2009.00897.x","volume":"10","author":"Mancini M.","year":"2009","journal-title":"Traffic"},{"issue":"12","key":"ref9\/cit9","first-page":"5150","volume":"8","author":"Isaya G.","year":"1988","journal-title":"Mol. Cell. Biol."},{"issue":"6384","key":"ref10\/cit10","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1038\/358325a0","volume":"358","author":"Rizzuto R.","year":"1992","journal-title":"Nature"},{"issue":"3","key":"ref11\/cit11","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1021\/cb600492a","volume":"2","author":"Ozawa T.","year":"2007","journal-title":"ACS Chem. Biol."},{"issue":"1","key":"ref12\/cit12","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1021\/mp200461s","volume":"9","author":"Dixon A. S.","year":"2012","journal-title":"Mol. Pharmaceutics"},{"issue":"4","key":"ref13\/cit13","doi-asserted-by":"crossref","first-page":"1098","DOI":"10.1007\/s11095-011-0654-8","volume":"29","author":"Dixon A. S.","year":"2011","journal-title":"Pharm. Res."},{"issue":"6","key":"ref14\/cit14","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1016\/S1074-7613(00)80452-5","volume":"6","author":"Afar D. E.","year":"1997","journal-title":"Immunity"},{"issue":"21","key":"ref15\/cit15","doi-asserted-by":"crossref","first-page":"18960","DOI":"10.1074\/jbc.M301807200","volume":"278","author":"Robin M. A.","year":"2003","journal-title":"J. Biol. Chem."},{"key":"ref16\/cit16","volume":"3","author":"Strober W.","year":"2001","journal-title":"Curr. Protoc. Immunol"},{"issue":"31","key":"ref17\/cit17","doi-asserted-by":"crossref","first-page":"27751","DOI":"10.1074\/jbc.M111.264903","volume":"286","author":"Dixon A. S.","year":"2011","journal-title":"J. Biol. Chem."},{"key":"ref18\/cit18","unstructured":"Rasband, W. S.Available atwww.uhnres.utoronto.ca\/facilities\/wcif\/imagej\/image_intensity_proce.htm#intensity_BG, 2004."},{"issue":"3","key":"ref19\/cit19","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1111\/j.1365-2818.2006.01706.x","volume":"224","author":"Bolte S.","year":"2006","journal-title":"J. Microsc."},{"issue":"6","key":"ref20\/cit20","doi-asserted-by":"crossref","first-page":"3993","DOI":"10.1529\/biophysj.103.038422","volume":"86","author":"Costes S. V.","year":"2004","journal-title":"Biophys. J."},{"issue":"6","key":"ref21\/cit21","doi-asserted-by":"crossref","first-page":"710","DOI":"10.1017\/S143192761009389X","volume":"16","author":"Barlow A. L.","year":"2010","journal-title":"Microsc. Microanal."},{"issue":"1","key":"ref22\/cit22","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/j.jneumeth.2005.01.012","volume":"146","author":"Jaskolski F.","year":"2005","journal-title":"J. Neurosci. Methods"},{"issue":"1","key":"ref23\/cit23","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/S0022-1759(02)00072-8","volume":"265","author":"Lecoeur H.","year":"2002","journal-title":"J. Immunol. Methods"},{"issue":"5","key":"ref24\/cit24","doi-asserted-by":"crossref","first-page":"1449","DOI":"10.1021\/mp3000259","volume":"9","author":"Mossalam M.","year":"2012","journal-title":"Mol. Pharmaceutics"},{"key":"ref25\/cit25","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1007\/978-1-61779-860-3_5","volume":"887","author":"Kyrylkova K.","year":"2012","journal-title":"Methods Mol. Biol."},{"issue":"1","key":"ref26\/cit26","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/(SICI)1097-0320(19980101)31:1<1::AID-CYTO1>3.0.CO;2-R","volume":"31","author":"van Engeland M.","year":"1998","journal-title":"Cytometry"},{"issue":"10","key":"ref27\/cit27","doi-asserted-by":"crossref","first-page":"3829","DOI":"10.1182\/blood.V92.10.3829.422k14_3829_3840","volume":"92","author":"Zhang X.","year":"1998","journal-title":"Blood"},{"issue":"1","key":"ref28\/cit28","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1038\/cdd.2008.150","volume":"16","author":"Kroemer G.","year":"2009","journal-title":"Cell Death Differ."},{"issue":"2","key":"ref29\/cit29","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1124\/mol.63.2.276","volume":"63","author":"Kumar S.","year":"2003","journal-title":"Mol. Pharmacol."},{"issue":"2","key":"ref30\/cit30","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1002\/ijc.23063","volume":"122","author":"Galan-Moya E. M.","year":"2008","journal-title":"Int. J. Cancer"},{"issue":"2","key":"ref31\/cit31","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/j.mam.2010.02.008","volume":"31","author":"Ralph S. J.","year":"2010","journal-title":"Mol. Aspects Med."},{"issue":"32","key":"ref32\/cit32","doi-asserted-by":"crossref","first-page":"24273","DOI":"10.1074\/jbc.M002094200","volume":"275","author":"Sattler M.","year":"2000","journal-title":"J. Biol. Chem."},{"issue":"2","key":"ref33\/cit33","doi-asserted-by":"crossref","first-page":"e17020","DOI":"10.1371\/journal.pone.0017020","volume":"6","author":"Preyer M.","year":"2011","journal-title":"PLoS One"},{"issue":"52","key":"ref34\/cit34","doi-asserted-by":"crossref","first-page":"33260","DOI":"10.1074\/jbc.272.52.33260","volume":"272","author":"Warmuth M.","year":"1997","journal-title":"J. Biol. Chem."},{"issue":"12","key":"ref35\/cit35","doi-asserted-by":"crossref","first-page":"842","DOI":"10.1038\/nrc2960","volume":"10","author":"Vigil D.","year":"2010","journal-title":"Nat. Rev. Cancer"},{"issue":"6","key":"ref36\/cit36","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1016\/j.ceca.2006.03.001","volume":"39","author":"Vichalkovski A.","year":"2006","journal-title":"Cell Calcium"},{"issue":"19","key":"ref37\/cit37","doi-asserted-by":"crossref","first-page":"4186","DOI":"10.1182\/blood-2009-05-219550","volume":"114","author":"Pellicano F.","year":"2009","journal-title":"Blood"},{"issue":"11","key":"ref38\/cit38","doi-asserted-by":"crossref","first-page":"e7889","DOI":"10.1371\/journal.pone.0007889","volume":"4","author":"Robert G.","year":"2009","journal-title":"PLoS One"},{"issue":"11","key":"ref39\/cit39","doi-asserted-by":"crossref","first-page":"4122","DOI":"10.1182\/blood.V99.11.4122","volume":"99","author":"Wertheim J. A.","year":"2002","journal-title":"Blood"}],"container-title":["Molecular Pharmaceutics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/mp3003539","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,22]],"date-time":"2023-04-22T01:28:29Z","timestamp":1682126909000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/mp3003539"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,10,12]]},"references-count":39,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2012,11,5]]}},"alternative-id":["10.1021\/mp3003539"],"URL":"https:\/\/doi.org\/10.1021\/mp3003539","relation":{},"ISSN":["1543-8384","1543-8392"],"issn-type":[{"value":"1543-8384","type":"print"},{"value":"1543-8392","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,10,12]]}}}