{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,19]],"date-time":"2025-11-19T17:09:58Z","timestamp":1763572198030},"reference-count":46,"publisher":"American Chemical Society (ACS)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Mol. Pharmaceutics"],"published-print":{"date-parts":[[2014,2,3]]},"DOI":"10.1021\/mp4004089","type":"journal-article","created":{"date-parts":[[2013,12,23]],"date-time":"2013-12-23T05:50:25Z","timestamp":1387777825000},"page":"445-456","source":"Crossref","is-referenced-by-count":9,"title":["Preclinical Evaluation of DO3A-Act-AQ: A Polyazamacrocyclic Monomeric Anthraquinone Derivative as a Theranostic Agent"],"prefix":"10.1021","volume":"11","author":[{"given":"Anupriya","family":"Adhikari","sequence":"first","affiliation":[{"name":"Division of Cyclotron and Radiopharmaceutical Sciences, Institute of Nuclear Medicine and Allied Sciences, Defence Research & Development Organization, Brig S K Mazumdar Road, Delhi-110054, India"},{"name":"Department\rof Chemistry, Kanya Gurukul Campus, Gurukul Kangri Vishwavidyalaya, Haridwar-249404, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anupama","family":"Datta","sequence":"additional","affiliation":[{"name":"Division of Cyclotron and Radiopharmaceutical Sciences, Institute of Nuclear Medicine and Allied Sciences, Defence Research & Development Organization, Brig S K Mazumdar Road, Delhi-110054, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manish","family":"Adhikari","sequence":"additional","affiliation":[{"name":"Division of Radiation Biosciences, Institute of Nuclear Medicine and Allied Sciences, Defence Research & Development Organization, Brig S K Mazumdar Road, Delhi-110054, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kanchan","family":"Chauhan","sequence":"additional","affiliation":[{"name":"Division of Cyclotron and Radiopharmaceutical Sciences, Institute of Nuclear Medicine and Allied Sciences, Defence Research & Development Organization, Brig S K Mazumdar Road, Delhi-110054, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Krishna","family":"Chuttani","sequence":"additional","affiliation":[{"name":"Division of Cyclotron and Radiopharmaceutical Sciences, Institute of Nuclear Medicine and Allied Sciences, Defence Research & Development Organization, Brig S K Mazumdar Road, Delhi-110054, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sanjiv","family":"Saw","sequence":"additional","affiliation":[{"name":"Division of Clinical PET, Institute of Nuclear Medicine and Allied Sciences, Defence Research & Development Organization, Brig S K Mazumdar Road, Delhi-110054, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abha","family":"Shukla","sequence":"additional","affiliation":[{"name":"Department\rof Chemistry, Kanya Gurukul Campus, Gurukul Kangri Vishwavidyalaya, Haridwar-249404, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anil K.","family":"Mishra","sequence":"additional","affiliation":[{"name":"Division of Cyclotron and Radiopharmaceutical Sciences, Institute of Nuclear Medicine and Allied Sciences, Defence Research & Development Organization, Brig S K Mazumdar Road, Delhi-110054, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"316","published-online":{"date-parts":[[2014,1,2]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"crossref","first-page":"2961","DOI":"10.1021\/mp3002733","volume":"9","author":"Danhier F.","year":"2012","journal-title":"Mol. Pharmaceutics"},{"key":"ref2\/cit2","doi-asserted-by":"crossref","first-page":"1959","DOI":"10.1021\/mp100269f","volume":"7","author":"Mohan P.","year":"2010","journal-title":"Mol. Pharmaceutics"},{"key":"ref3\/cit3","doi-asserted-by":"crossref","first-page":"1469","DOI":"10.1016\/S0968-0896(97)00097-7","volume":"5","author":"Johnson M. G.","year":"1997","journal-title":"Bioorg. Med. Chem."},{"key":"ref4\/cit4","doi-asserted-by":"crossref","first-page":"3374","DOI":"10.1039\/c1cc00111f","volume":"47","author":"Jones J. E.","year":"2011","journal-title":"Chem. Commun."},{"key":"ref5\/cit5","doi-asserted-by":"crossref","first-page":"5835","DOI":"10.1021\/om300475y","volume":"31","author":"Balasingham R. G.","year":"2012","journal-title":"Organometallics"},{"key":"ref6\/cit6","doi-asserted-by":"crossref","first-page":"3300","DOI":"10.1021\/jm020492l","volume":"46","author":"Huang H. S.","year":"2003","journal-title":"J. Med. Chem."},{"key":"ref7\/cit7","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/cddis.2012.187","volume":"4","author":"Jackson T. C.","year":"2013","journal-title":"Cell Death Dis."},{"key":"ref8\/cit8","first-page":"291","volume":"5","author":"Teissier E. M.","year":"1990","journal-title":"Anti Cancer Drug Des."},{"key":"ref9\/cit9","doi-asserted-by":"crossref","first-page":"2084","DOI":"10.1021\/jm00067a005","volume":"36","author":"Teissier E. M.","year":"1993","journal-title":"J. Med. Chem."},{"key":"ref10\/cit10","first-page":"515","volume":"10","author":"Meikle I.","year":"1995","journal-title":"Anti Cancer Drug Des."},{"key":"ref11\/cit11","doi-asserted-by":"crossref","first-page":"3114","DOI":"10.1021\/jm950924a","volume":"39","author":"Gatto B.","year":"1996","journal-title":"J. Med. Chem."},{"key":"ref12\/cit12","doi-asserted-by":"crossref","first-page":"204","DOI":"10.3998\/ark.5550190.0005.519","volume":"5","author":"Zagotto G.","year":"2004","journal-title":"Arkivoc"},{"key":"ref13\/cit13","doi-asserted-by":"crossref","first-page":"3439","DOI":"10.1016\/j.bmc.2005.03.001","volume":"13","author":"Teng C. H.","year":"2005","journal-title":"Bioorg. Med. Chem."},{"key":"ref14\/cit14","doi-asserted-by":"crossref","first-page":"5670","DOI":"10.1016\/j.bmc.2011.07.021","volume":"19","author":"Tu H. Y.","year":"2011","journal-title":"Bioorg. Med. Chem."},{"key":"ref15\/cit15","doi-asserted-by":"crossref","first-page":"6163","DOI":"10.1016\/j.bmc.2004.09.001","volume":"12","author":"Huang H. S.","year":"2004","journal-title":"Bioorg. Med. Chem."},{"key":"ref16\/cit16","doi-asserted-by":"crossref","first-page":"2858","DOI":"10.1021\/cr900325h","volume":"110","author":"Wadas T. J.","year":"2010","journal-title":"J. Chem. Rev."},{"key":"ref17\/cit17","doi-asserted-by":"crossref","first-page":"2903","DOI":"10.1021\/cr1000755","volume":"110","author":"Bartholoma M. D.","year":"2010","journal-title":"J. Chem. Rev."},{"key":"ref18\/cit18","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1021\/ic025790n","volume":"42","author":"Benetollo F.","year":"2003","journal-title":"Inorg. Chem."},{"key":"ref19\/cit19","doi-asserted-by":"crossref","first-page":"3346","DOI":"10.1039\/c0dt01370f","volume":"40","author":"Tanwar J.","year":"2011","journal-title":"Dalton Trans."},{"key":"ref20\/cit20","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1021\/bc0601673","volume":"18","author":"Antunes P.","year":"2007","journal-title":"Bioconjugate Chem."},{"key":"ref21\/cit21","doi-asserted-by":"crossref","first-page":"200","DOI":"10.3109\/09553002.2013.741285","volume":"89","author":"Adhikari M.","year":"2013","journal-title":"Int. J. Radiat. Biol."},{"key":"ref22\/cit22","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1021\/bc100382c","volume":"22","author":"Tanwar J.","year":"2011","journal-title":"Bioconjugate Chem."},{"key":"ref23\/cit23","doi-asserted-by":"crossref","first-page":"2126","DOI":"10.1021\/bc200389w","volume":"22","author":"Zagotto G.","year":"2011","journal-title":"Bioconjugate Chem."},{"key":"ref24\/cit24","doi-asserted-by":"crossref","first-page":"6976","DOI":"10.1016\/j.bmc.2008.05.072","volume":"16","author":"Huang H.","year":"2008","journal-title":"Bioorg. Med. Chem."},{"key":"ref25\/cit25","doi-asserted-by":"crossref","first-page":"2176","DOI":"10.1016\/j.bmc.2011.02.041","volume":"19","author":"Hoigebazar L.","year":"2011","journal-title":"Bioorg. Med. Chem."},{"key":"ref26\/cit26","doi-asserted-by":"crossref","first-page":"554","DOI":"10.1021\/bc030078f","volume":"15","author":"Velikyan I.","year":"2004","journal-title":"Bioconjugate Chem."},{"key":"ref27\/cit27","doi-asserted-by":"crossref","first-page":"4509","DOI":"10.1039\/b820375j","volume":"23","author":"Lacerda S.","year":"2009","journal-title":"Dalton Trans."},{"key":"ref28\/cit28","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1002\/cmmi.451","volume":"6","author":"Riss P. J.","year":"2011","journal-title":"Contrast Media Mol. Imaging"},{"key":"ref29\/cit29","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/j.nucmedbio.2012.11.001","volume":"40","author":"Chakravarty R.","year":"2013","journal-title":"Nucl. Med. Biol."},{"key":"ref30\/cit30","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1002\/cmmi.232","volume":"3","author":"Fani M.","year":"2008","journal-title":"Contrast Media Mol. Imaging"},{"key":"ref31\/cit31","doi-asserted-by":"crossref","first-page":"4563","DOI":"10.1002\/ejoc.200700418","author":"Tietze L. F.","year":"2007","journal-title":"Eur. J. Org. Chem."},{"key":"ref32\/cit32","doi-asserted-by":"crossref","first-page":"6505","DOI":"10.1016\/j.bmcl.2008.10.047","volume":"18","author":"Wang S.","year":"2008","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"ref33\/cit33","doi-asserted-by":"crossref","first-page":"3300","DOI":"10.1021\/jm020492l","volume":"46","author":"Huang H.","year":"2003","journal-title":"J. Med. Chem."},{"key":"ref34\/cit34","doi-asserted-by":"crossref","first-page":"5566","DOI":"10.1021\/jm800160v","volume":"51","author":"Zagotto G.","year":"2008","journal-title":"J. Med. Chem."},{"key":"ref35\/cit35","doi-asserted-by":"crossref","first-page":"6163","DOI":"10.1016\/j.bmc.2004.09.001","volume":"12","author":"Huang H.","year":"2004","journal-title":"Bioorg. Med. Chem."},{"key":"ref36\/cit36","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1053\/j.semnuclmed.2011.02.001","volume":"41","author":"Breeman W. A.","year":"2011","journal-title":"Semin. Nucl. Med."},{"key":"ref37\/cit37","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1016\/S0969-8051(02)00290-1","volume":"29","author":"Hua F.","year":"2002","journal-title":"Nucl. Med. Biol."},{"key":"ref38\/cit38","doi-asserted-by":"crossref","first-page":"477","DOI":"10.2967\/jnumed.109.069716","volume":"51","author":"Costantini D. L.","year":"2010","journal-title":"J. Nucl. Med."},{"key":"ref39\/cit39","first-page":"13","volume":"3","author":"Viola-Villegas N.","year":"2008","journal-title":"Target Insights"},{"key":"ref40\/cit40","doi-asserted-by":"crossref","first-page":"6505","DOI":"10.1016\/j.bmcl.2008.10.047","volume":"18","author":"Wang S.","year":"2008","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"ref41\/cit41","doi-asserted-by":"crossref","first-page":"5670","DOI":"10.1016\/j.bmc.2011.07.021","volume":"19","author":"Tua H.","year":"2011","journal-title":"Bioorg. Med. Chem."},{"key":"ref42\/cit42","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/0022-2836(67)90353-1","volume":"27","author":"Lepecq J. B.","year":"1967","journal-title":"J. Mol. Biol."},{"key":"ref43\/cit43","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1002\/jbt.21487","volume":"27","author":"Yang H.","year":"2013","journal-title":"J. Biochem Mol. Toxicology"},{"key":"ref44\/cit44","doi-asserted-by":"crossref","first-page":"2654","DOI":"10.1039\/c0nj00347f","volume":"34","author":"Xu W.","year":"2010","journal-title":"New J. Chem."},{"key":"ref45\/cit45","doi-asserted-by":"crossref","first-page":"490","DOI":"10.1021\/bc700322w","volume":"19","author":"Sheng X.","year":"2008","journal-title":"Bioconjugate Chem."},{"key":"ref46\/cit46","doi-asserted-by":"crossref","first-page":"858","DOI":"10.1021\/cr3003104","volume":"113","author":"Cutler C. S.","year":"2013","journal-title":"Chem. Rev."}],"container-title":["Molecular Pharmaceutics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/mp4004089","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,3]],"date-time":"2023-04-03T23:30:25Z","timestamp":1680564625000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/mp4004089"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,1,2]]},"references-count":46,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2014,2,3]]}},"alternative-id":["10.1021\/mp4004089"],"URL":"https:\/\/doi.org\/10.1021\/mp4004089","relation":{},"ISSN":["1543-8384","1543-8392"],"issn-type":[{"value":"1543-8384","type":"print"},{"value":"1543-8392","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,1,2]]}}}