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Des."},{"key":"ref19\/cit19","first-page":"1","author":"Hong G.","year":"2008","journal-title":"Biomed. Microdevices"},{"key":"ref20\/cit20","doi-asserted-by":"crossref","first-page":"873","DOI":"10.1016\/S0142-9612(01)00196-X","volume":"23","author":"Park Y. J.","year":"2002","journal-title":"Biomaterials"},{"key":"ref21\/cit21","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/S0169-409X(02)00019-4","volume":"54","author":"Torchilin V. P.","year":"2002","journal-title":"Adv. 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Cancer Inst."},{"key":"ref27\/cit27","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/S0168-3659(98)00083-2","volume":"56","author":"Kim S. Y.","year":"1998","journal-title":"J. Controlled Release"},{"key":"ref28\/cit28","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1023\/A:1020186505848","volume":"22","author":"Allen C.","year":"2002","journal-title":"Biosci. Rep."},{"key":"ref29\/cit29","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/0005-2736(91)90201-I","volume":"1068","author":"Allen T. M.","year":"1991","journal-title":"Biochem. Biophys. Acta."},{"key":"ref30\/cit30","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s11095-006-9132-0","volume":"24","author":"Torchilin V. P.","year":"2007","journal-title":"Pharm. Res."},{"key":"ref31\/cit31","first-page":"3352","volume":"54","author":"Yuan F.","year":"1994","journal-title":"Cancer Res."},{"key":"ref32\/cit32","first-page":"3748","volume":"6","author":"Matteucci M. 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