{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T13:06:27Z","timestamp":1790859987967,"version":"4.1.0"},"reference-count":30,"publisher":"American Chemical Society (ACS)","issue":"10","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nano Lett."],"published-print":{"date-parts":[[2005,10,1]]},"DOI":"10.1021\/nl051624b","type":"journal-article","created":{"date-parts":[[2005,10,12]],"date-time":"2005-10-12T05:07:49Z","timestamp":1129093669000},"page":"2050-2057","source":"Crossref","is-referenced-by-count":280,"title":["Multihydroxylated [Gd@C<sub>82<\/sub>(OH)<sub>22<\/sub>]<i><sub>n<\/sub><\/i> Nanoparticles:\u2009 Antineoplastic Activity of High Efficiency and Low Toxicity"],"prefix":"10.1021","volume":"5","author":[{"given":"Chunying","family":"Chen","sequence":"first","affiliation":[{"name":"Lab for Bio-Environmental Health Sciences of Nanoscale Materials and Key Lab of Nuclear Analytical Techniques, Institute of High Energy Physics, Chinese Academy of Sciences, Beijing 100049, China, School of Public Health, Department of Clinical Laboratory, Third Hospital of Peking University, Beijing 100083, China, Key Lab of Molecular Nanostructures and Nanotechnology, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100080, China, and The Graduate School, Chinese Academy of Sciences,..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gengmei","family":"Xing","sequence":"additional","affiliation":[{"name":"Lab for Bio-Environmental Health Sciences of Nanoscale Materials and Key Lab of Nuclear Analytical Techniques, Institute of High Energy Physics, Chinese Academy of Sciences, Beijing 100049, China, School of Public Health, Department of Clinical Laboratory, Third Hospital of Peking University, Beijing 100083, China, Key Lab of Molecular Nanostructures and Nanotechnology, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100080, China, and The Graduate School, Chinese Academy of Sciences,..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiangxue","family":"Wang","sequence":"additional","affiliation":[{"name":"Lab for Bio-Environmental Health Sciences of Nanoscale Materials and Key Lab of Nuclear Analytical Techniques, Institute of High Energy Physics, Chinese Academy of Sciences, Beijing 100049, China, School of Public Health, Department of Clinical Laboratory, Third Hospital of Peking University, Beijing 100083, China, Key Lab of Molecular Nanostructures and Nanotechnology, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100080, China, and The Graduate School, Chinese Academy of Sciences,..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuliang","family":"Zhao","sequence":"additional","affiliation":[{"name":"Lab for Bio-Environmental Health Sciences of Nanoscale Materials and Key Lab of Nuclear Analytical Techniques, Institute of High Energy Physics, Chinese Academy of Sciences, Beijing 100049, China, School of Public Health, Department of Clinical Laboratory, Third Hospital of Peking University, Beijing 100083, China, Key Lab of Molecular Nanostructures and Nanotechnology, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100080, China, and The Graduate School, Chinese Academy of Sciences,..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bai","family":"Li","sequence":"additional","affiliation":[{"name":"Lab for Bio-Environmental Health Sciences of Nanoscale Materials and Key Lab of Nuclear Analytical Techniques, Institute of High Energy Physics, Chinese Academy of Sciences, Beijing 100049, China, School of Public Health, Department of Clinical Laboratory, Third Hospital of Peking University, Beijing 100083, China, Key Lab of Molecular Nanostructures and Nanotechnology, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100080, China, and The Graduate School, Chinese Academy of Sciences,..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun","family":"Tang","sequence":"additional","affiliation":[{"name":"Lab for Bio-Environmental Health Sciences of Nanoscale Materials and Key Lab of Nuclear Analytical Techniques, Institute of High Energy Physics, Chinese Academy of Sciences, Beijing 100049, China, School of Public Health, Department of Clinical Laboratory, Third Hospital of Peking University, Beijing 100083, China, Key Lab of Molecular Nanostructures and Nanotechnology, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100080, China, and The Graduate School, Chinese Academy of Sciences,..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guang","family":"Jia","sequence":"additional","affiliation":[{"name":"Lab for Bio-Environmental Health Sciences of Nanoscale Materials and Key Lab of Nuclear Analytical Techniques, Institute of High Energy Physics, Chinese Academy of Sciences, Beijing 100049, China, School of Public Health, Department of Clinical Laboratory, Third Hospital of Peking University, Beijing 100083, China, Key Lab of Molecular Nanostructures and Nanotechnology, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100080, China, and The Graduate School, Chinese Academy of Sciences,..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tiancheng","family":"Wang","sequence":"additional","affiliation":[{"name":"Lab for Bio-Environmental Health Sciences of Nanoscale Materials and Key Lab of Nuclear Analytical Techniques, Institute of High Energy Physics, Chinese Academy of Sciences, Beijing 100049, China, School of Public Health, Department of Clinical Laboratory, Third Hospital of Peking University, Beijing 100083, China, Key Lab of Molecular Nanostructures and Nanotechnology, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100080, China, and The Graduate School, Chinese Academy of Sciences,..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jin","family":"Sun","sequence":"additional","affiliation":[{"name":"Lab for Bio-Environmental Health Sciences of Nanoscale Materials and Key Lab of Nuclear Analytical Techniques, Institute of High Energy Physics, Chinese Academy of Sciences, Beijing 100049, China, School of Public Health, Department of Clinical Laboratory, Third Hospital of Peking University, Beijing 100083, China, Key Lab of Molecular Nanostructures and Nanotechnology, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100080, China, and The Graduate School, Chinese Academy of Sciences,..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li","family":"Xing","sequence":"additional","affiliation":[{"name":"Lab for Bio-Environmental Health Sciences of Nanoscale Materials and Key Lab of Nuclear Analytical Techniques, Institute of High Energy Physics, Chinese Academy of Sciences, Beijing 100049, China, School of Public Health, Department of Clinical Laboratory, Third Hospital of Peking University, Beijing 100083, China, Key Lab of Molecular Nanostructures and Nanotechnology, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100080, China, and The Graduate School, Chinese Academy of Sciences,..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hui","family":"Yuan","sequence":"additional","affiliation":[{"name":"Lab for Bio-Environmental Health Sciences of Nanoscale Materials and Key Lab of Nuclear Analytical Techniques, Institute of High Energy Physics, Chinese Academy of Sciences, Beijing 100049, China, School of Public Health, Department of Clinical Laboratory, Third Hospital of Peking University, Beijing 100083, China, Key Lab of Molecular Nanostructures and Nanotechnology, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100080, China, and The Graduate School, Chinese Academy of Sciences,..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuxi","family":"Gao","sequence":"additional","affiliation":[{"name":"Lab for Bio-Environmental Health Sciences of Nanoscale Materials and Key Lab of Nuclear Analytical Techniques, Institute of High Energy Physics, Chinese Academy of Sciences, Beijing 100049, China, School of Public Health, Department of Clinical Laboratory, Third Hospital of Peking University, Beijing 100083, China, Key Lab of Molecular Nanostructures and Nanotechnology, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100080, China, and The Graduate School, Chinese Academy of Sciences,..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huan","family":"Meng","sequence":"additional","affiliation":[{"name":"Lab for Bio-Environmental Health Sciences of Nanoscale Materials and Key Lab of Nuclear Analytical Techniques, Institute of High Energy Physics, Chinese Academy of Sciences, Beijing 100049, China, School of Public Health, Department of Clinical Laboratory, Third Hospital of Peking University, Beijing 100083, China, Key Lab of Molecular Nanostructures and Nanotechnology, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100080, China, and The Graduate School, Chinese Academy of Sciences,..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhen","family":"Chen","sequence":"additional","affiliation":[{"name":"Lab for Bio-Environmental Health Sciences of Nanoscale Materials and Key Lab of Nuclear Analytical Techniques, Institute of High Energy Physics, Chinese Academy of Sciences, Beijing 100049, China, School of Public Health, Department of Clinical Laboratory, Third Hospital of Peking University, Beijing 100083, China, Key Lab of Molecular Nanostructures and Nanotechnology, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100080, China, and The Graduate School, Chinese Academy of Sciences,..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Feng","family":"Zhao","sequence":"additional","affiliation":[{"name":"Lab for Bio-Environmental Health Sciences of Nanoscale Materials and Key Lab of Nuclear Analytical Techniques, Institute of High Energy Physics, Chinese Academy of Sciences, Beijing 100049, China, School of Public Health, Department of Clinical Laboratory, Third Hospital of Peking University, Beijing 100083, China, Key Lab of Molecular Nanostructures and Nanotechnology, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100080, China, and The Graduate School, Chinese Academy of Sciences,..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhifang","family":"Chai","sequence":"additional","affiliation":[{"name":"Lab for Bio-Environmental Health Sciences of Nanoscale Materials and Key Lab of Nuclear Analytical Techniques, Institute of High Energy Physics, Chinese Academy of Sciences, Beijing 100049, China, School of Public Health, Department of Clinical Laboratory, Third Hospital of Peking University, Beijing 100083, China, Key Lab of Molecular Nanostructures and Nanotechnology, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100080, China, and The Graduate School, Chinese Academy of Sciences,..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaohong","family":"Fang","sequence":"additional","affiliation":[{"name":"Lab for Bio-Environmental Health Sciences of Nanoscale Materials and Key Lab of Nuclear Analytical Techniques, Institute of High Energy Physics, Chinese Academy of Sciences, Beijing 100049, China, School of Public Health, Department of Clinical Laboratory, Third Hospital of Peking University, Beijing 100083, China, Key Lab of Molecular Nanostructures and Nanotechnology, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100080, China, and The Graduate School, Chinese Academy of Sciences,..."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2005,9,27]]},"reference":[{"key":"nl051624bb00001\/nl051624bb00001_1","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1038\/318162a0","volume":"318","author":"Kroto H. M.","year":"1985","journal-title":"Nature"},{"key":"nl051624bb00002\/nl051624bb00002_1","first-page":"1710","volume":"37","author":"Schinazi R. F.","year":"1993","journal-title":"Antimicrob. Agents Chemother."},{"key":"nl051624bb00003\/nl051624bb00003_1","doi-asserted-by":"crossref","first-page":"3958","DOI":"10.1021\/ol000217y","volume":"2","author":"Marcorin G. L.","year":"2000","journal-title":"Org. Lett."},{"key":"nl051624bb00004\/nl051624bb00004_1","doi-asserted-by":"crossref","first-page":"1116","DOI":"10.1111\/j.1349-7006.1997.tb00336.x","volume":"88","author":"Tabata Y.","year":"1997","journal-title":"Jpn. J. Cancer Res."},{"key":"nl051624bb00005\/nl051624bb00005_1","doi-asserted-by":"crossref","first-page":"2053","DOI":"10.1351\/pac199971112047","volume":"71","author":"Tabata Y.","year":"1999","journal-title":"Pure Appl. Chem."},{"key":"nl051624bb00006\/nl051624bb00006_1","first-page":"9439","volume":"94","author":"Dugan L. L.","year":"1997","journal-title":"Proc. Natl. Acad. Sci., U.S.A."},{"key":"nl051624bb00007\/nl051624bb00007_1","first-page":"1202","volume":"37","author":"Ali S. S.","year":"2004","journal-title":"Free Radical Biol. Med."},{"key":"nl051624bb00008\/nl051624bb00008_1","doi-asserted-by":"crossref","first-page":"1170","DOI":"10.1038\/nbt875","volume":"21","author":"Colvin V. L.","year":"2003","journal-title":"Nat. Biotechnol."},{"key":"nl051624bb00009\/nl051624bb00009_1","first-page":"207","volume":"192","author":"Wilson L. J.","year":"1999","journal-title":"J. Coord. Chem. Rev."},{"key":"nl051624bb00010\/nl051624bb00010_1","doi-asserted-by":"crossref","first-page":"5270","DOI":"10.1021\/jp004077l","volume":"105","author":"Simonin J. P.","year":"2001","journal-title":"J. Phys. Chem. B"},{"key":"nl051624bb00011\/nl051624bb00011_1","doi-asserted-by":"crossref","first-page":"5187","DOI":"10.1073\/pnas.96.9.5182","volume":"96","author":"Cagle D. W.","year":"1999","journal-title":"J. Proc. Natl. Acad. Sci., U.S.A."},{"key":"nl051624bb00012\/nl051624bb00012_1","doi-asserted-by":"crossref","first-page":"S497","DOI":"10.1016\/S1076-6332(03)80274-X","volume":"9","author":"Okumura M.","year":"2002","journal-title":"Acad. Radiol."},{"key":"nl051624bb00013\/nl051624bb00013_1","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1021\/bc000136m","volume":"12","author":"Mikawa M.","year":"2001","journal-title":"Bioconjugate Chem."},{"key":"nl051624bb00014\/nl051624bb00014_1","doi-asserted-by":"crossref","first-page":"5478","DOI":"10.1021\/ja0340984","volume":"125","author":"Bolskar R. D.","year":"2003","journal-title":"J. Am. Chem. Soc."},{"key":"nl051624bb00015\/nl051624bb00015_1","first-page":"11479","volume":"108","author":"Xing G. M.","year":"2004","journal-title":"J. Phys. Chem. B"},{"key":"nl051624bb00016\/nl051624bb00016_1","doi-asserted-by":"crossref","first-page":"8785","DOI":"10.1021\/jp050024y","volume":"109","author":"Tang J.","year":"2005","journal-title":"J. Phys. Chem. B"},{"key":"nl051624bb00017\/nl051624bb00017_1","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1038\/347354a0","volume":"347","author":"Kr\u00e4tschmer W.","year":"1990","journal-title":"Nature"},{"key":"nl051624bb00018\/nl051624bb00018_1","first-page":"1596","volume":"40","author":"Sun B.","year":"2002","journal-title":"Carbon"},{"key":"nl051624bb00019\/nl051624bb00019_1","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1021\/ja005618n","volume":"123","author":"Akiyama K.","year":"2001","journal-title":"J. Am. Chem. Soc."},{"key":"nl051624bb00020\/nl051624bb00020_1","first-page":"11135","volume":"126","author":"Zhao Y. L.","year":"2004","journal-title":"J. Am. Chem. Soc."},{"key":"nl051624bb00021\/nl051624bb00021_1","first-page":"665","volume":"663","author":"Ros D. T.","year":"1999","journal-title":"Chem. Commun."},{"key":"nl051624bb00022\/nl051624bb00022_1","doi-asserted-by":"crossref","first-page":"1887","DOI":"10.1021\/nl0489586","volume":"4","author":"Sayes C. M.","year":"2004","journal-title":"Nano Lett."},{"key":"nl051624bb00023\/nl051624bb00023_1","first-page":"686","volume":"84","author":"Zhu B. D.","year":"2004","journal-title":"Natl. Med. J. China"},{"key":"nl051624bb00024\/nl051624bb00024_1","first-page":"6","volume":"11","author":"Yang Y. L.","year":"2005","journal-title":"World J. Gastroenterol."},{"key":"nl051624bb00025\/nl051624bb00025_1","volume-title":"Tietz Textbook of Clinical Chemistry","author":"Moss D. W.","year":"1994","edition":"2"},{"key":"nl051624bb00026\/nl051624bb00026_1","unstructured":"Asparate Aminotransferase. Laboratory Tests and Diagnostic Procedures, 3rd ed.; Chernecky, C. C., Berger, B. J., Eds.; W. B. Saunders:\u2009 Philadelphia, PA, 2001; pp 189\u2212191."},{"key":"nl051624bb00027\/nl051624bb00027_1","first-page":"521","volume":"10","author":"Ben-Hur H.","year":"2002","journal-title":"Int. J. Mol. Med."},{"key":"nl051624bb00028\/nl051624bb00028_1","first-page":"386","volume":"31","author":"Wang J. Y.","year":"1993","journal-title":"Cancer Chemother. Pharmacol."},{"key":"nl051624bb00029\/nl051624bb00029_1","doi-asserted-by":"crossref","first-page":"1079","DOI":"10.1126\/science.271.5252.1079","volume":"271","author":"Jain R.","year":"1996","journal-title":"Science"},{"key":"nl051624bb00030\/nl051624bb00030_1","doi-asserted-by":"crossref","first-page":"4612","DOI":"10.1073\/pnas.95.8.4607","volume":"95","author":"Hobbs S. K.","year":"1998","journal-title":"Proc. Natl. Acad. Sci. U.S.A."}],"container-title":["Nano Letters"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/nl051624b","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,10,11]],"date-time":"2021-10-11T10:29:22Z","timestamp":1633948162000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/nl051624b"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,9,27]]},"references-count":30,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2005,10,1]]}},"alternative-id":["10.1021\/nl051624b"],"URL":"https:\/\/doi.org\/10.1021\/nl051624b","relation":{},"ISSN":["1530-6984","1530-6992"],"issn-type":[{"value":"1530-6984","type":"print"},{"value":"1530-6992","type":"electronic"}],"subject":[],"published":{"date-parts":[[2005,9,27]]}}}