{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T22:06:48Z","timestamp":1789510008020,"version":"build-2803163510"},"reference-count":26,"publisher":"American Chemical Society (ACS)","issue":"8","license":[{"start":{"date-parts":[[1999,1,1]],"date-time":"1999-01-01T00:00:00Z","timestamp":915148800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/pubs.acs.org\/page\/policy\/authorchoice_termsofuse.html"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Nat. Prod."],"published-print":{"date-parts":[[2011,8,26]]},"DOI":"10.1021\/np200343t","type":"journal-article","created":{"date-parts":[[2011,7,29]],"date-time":"2011-07-29T17:27:15Z","timestamp":1311960435000},"page":"1779-1786","source":"Crossref","is-referenced-by-count":62,"title":["Lignan Derivatives from <i>Krameria lappacea<\/i> Roots Inhibit Acute Inflammation in Vivo and Pro-inflammatory Mediators in Vitro"],"prefix":"10.1021","volume":"74","author":[{"given":"Lisa","family":"Baumgartner","sequence":"first","affiliation":[{"name":"Institute of Pharmacy\/Pharmacognosy and Center for Molecular Biosciences Innsbruck, University of Innsbruck, Josef-Moeller-Haus, Innrain 52c, 6020 Innsbruck, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silvio","family":"Sosa","sequence":"additional","affiliation":[{"name":"Department of Life Sciences, University of Trieste, Via A. Valerio 6, 34127 Trieste, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Atanas G.","family":"Atanasov","sequence":"additional","affiliation":[{"name":"Department of Pharmacognosy, University of Vienna, Althanstrasse 14, 1090 Vienna, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antje","family":"Bodensieck","sequence":"additional","affiliation":[{"name":"Institute of Pharmaceutical Sciences, Pharmacognosy, Karl-Franzens University Graz, Universit\u00e4tsplatz 4, 8010 Graz, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nanang","family":"Fakhrudin","sequence":"additional","affiliation":[{"name":"Department of Pharmacognosy, University of Vienna, Althanstrasse 14, 1090 Vienna, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julia","family":"Bauer","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Analytics, Pharmaceutical Institute, Eberhard-Karls-University Tuebingen, Auf der Morgenstelle 8, 72076 Tuebingen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giorgia Del","family":"Favero","sequence":"additional","affiliation":[{"name":"Department of Life Sciences, University of Trieste, Via A. Valerio 6, 34127 Trieste, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cristina","family":"Ponti","sequence":"additional","affiliation":[{"name":"Department of Life Sciences, University of Trieste, Via A. Valerio 6, 34127 Trieste, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elke H.","family":"Heiss","sequence":"additional","affiliation":[{"name":"Department of Pharmacognosy, University of Vienna, Althanstrasse 14, 1090 Vienna, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefan","family":"Schwaiger","sequence":"additional","affiliation":[{"name":"Institute of Pharmacy\/Pharmacognosy and Center for Molecular Biosciences Innsbruck, University of Innsbruck, Josef-Moeller-Haus, Innrain 52c, 6020 Innsbruck, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angela","family":"Ladurner","sequence":"additional","affiliation":[{"name":"Department of Pharmacognosy, University of Vienna, Althanstrasse 14, 1090 Vienna, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ute","family":"Widowitz","sequence":"additional","affiliation":[{"name":"Institute of Pharmaceutical Sciences, Pharmacognosy, Karl-Franzens University Graz, Universit\u00e4tsplatz 4, 8010 Graz, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roberto Della","family":"Loggia","sequence":"additional","affiliation":[{"name":"Department of Life Sciences, University of Trieste, Via A. Valerio 6, 34127 Trieste, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Judith M.","family":"Rollinger","sequence":"additional","affiliation":[{"name":"Institute of Pharmacy\/Pharmacognosy and Center for Molecular Biosciences Innsbruck, University of Innsbruck, Josef-Moeller-Haus, Innrain 52c, 6020 Innsbruck, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oliver","family":"Werz","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Analytics, Pharmaceutical Institute, Eberhard-Karls-University Tuebingen, Auf der Morgenstelle 8, 72076 Tuebingen, Germany"},{"name":"Department of Pharmaceutical\/Medicinal Chemistry, Institute of Pharmacy, Friedrich-Schiller-University Jena, 07743 Jena, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rudolf","family":"Bauer","sequence":"additional","affiliation":[{"name":"Institute of Pharmaceutical Sciences, Pharmacognosy, Karl-Franzens University Graz, Universit\u00e4tsplatz 4, 8010 Graz, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Verena M.","family":"Dirsch","sequence":"additional","affiliation":[{"name":"Department of Pharmacognosy, University of Vienna, Althanstrasse 14, 1090 Vienna, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aurelia","family":"Tubaro","sequence":"additional","affiliation":[{"name":"Department of Life Sciences, University of Trieste, Via A. Valerio 6, 34127 Trieste, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hermann","family":"Stuppner","sequence":"additional","affiliation":[{"name":"Institute of Pharmacy\/Pharmacognosy and Center for Molecular Biosciences Innsbruck, University of Innsbruck, Josef-Moeller-Haus, Innrain 52c, 6020 Innsbruck, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2011,7,29]]},"reference":[{"key":"ref1\/cit1","unstructured":"Simpson, B. B.InFlora Neotropica;New York Botanical Garden:New York, 1989; pp1\u2013108."},{"key":"ref2\/cit2","first-page":"397","volume":"45","author":"Simpson B. B.","year":"1991","journal-title":"Syst. Bot."},{"key":"ref3\/cit3","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1055\/s-2002-23167","volume":"68","author":"Carini M.","year":"2002","journal-title":"Planta Med."},{"key":"ref4\/cit4","unstructured":"ESCOP Monographs Supplement 2009;Georg Thieme Verlag:Stuttgart, 2009; pp213\u2013216."},{"key":"ref5\/cit5","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1055\/s-2006-962032","volume":"55","author":"Scholz E.","year":"1989","journal-title":"Planta Med."},{"key":"ref6\/cit6","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1055\/s-2007-971618","volume":"42","author":"Stahl E.","year":"1981","journal-title":"Planta Med."},{"key":"ref7\/cit7","first-page":"675","volume":"118","author":"Arnone A.","year":"1988","journal-title":"Gazz. Chim. Ital."},{"key":"ref8\/cit8","first-page":"397","volume":"120","author":"Arnone A.","year":"1990","journal-title":"Gazz. Chim. Ital."},{"key":"ref9\/cit9","doi-asserted-by":"crossref","first-page":"1303","DOI":"10.1002\/(SICI)1097-0231(199708)11:12<1303::AID-RCM966>3.0.CO;2-J","volume":"11","author":"Maffei Facino R.","year":"1997","journal-title":"Rapid Commun. Mass Spectrom."},{"key":"ref10\/cit10","doi-asserted-by":"crossref","first-page":"4459","DOI":"10.1016\/j.bmc.2009.05.018","volume":"17","author":"Sch\u00fchly W.","year":"2009","journal-title":"Bioorg. Med. Chem."},{"key":"ref11\/cit11","doi-asserted-by":"crossref","first-page":"696","DOI":"10.1039\/b514045p","volume":"22","author":"Saleem M.","year":"2005","journal-title":"Nat. Prod. Rep."},{"key":"ref12\/cit12","doi-asserted-by":"crossref","first-page":"1159","DOI":"10.1016\/S0031-9422(00)82370-5","volume":"26","author":"Achenbach H.","year":"1987","journal-title":"Phytochemistry"},{"key":"ref13\/cit13","doi-asserted-by":"crossref","first-page":"1831","DOI":"10.1039\/b801858h","volume":"6","author":"Clive D. L. J.","year":"2008","journal-title":"Org. Biomol. Chem."},{"key":"ref14\/cit14","doi-asserted-by":"crossref","first-page":"2307","DOI":"10.1039\/B302632A","volume":"1","author":"Moinuddin S. G. A.","year":"2003","journal-title":"Org. Biomol. Chem."},{"key":"ref15\/cit15","doi-asserted-by":"crossref","first-page":"1093","DOI":"10.1016\/S0031-9422(96)00412-8","volume":"43","author":"Achenbach H.","year":"1996","journal-title":"Phytochemistry"},{"key":"ref16\/cit16","doi-asserted-by":"crossref","first-page":"1959","DOI":"10.1016\/S0031-9422(00)97894-4","volume":"28","author":"Achenbach H.","year":"1989","journal-title":"Phytochemistry"},{"key":"ref17\/cit17","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1007\/BF01982641","volume":"17","author":"Tubaro A.","year":"1985","journal-title":"Agents Actions"},{"key":"ref18\/cit18","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1016\/j.bmcl.2010.10.051","volume":"21","author":"Noha S.","year":"2011","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"ref19\/cit19","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1124\/mol.109.062141","volume":"77","author":"Fakhrudin N.","year":"2010","journal-title":"Mol. Pharmacol."},{"key":"ref20\/cit20","doi-asserted-by":"crossref","first-page":"3740","DOI":"10.1210\/jcem.87.8.8729","volume":"87","author":"Raivio T.","year":"2002","journal-title":"J. Clin. Endocr. Metab."},{"key":"ref21\/cit21","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1111\/1523-1747.ep12506462","volume":"78","author":"Bradley P. P.","year":"1982","journal-title":"J. Invest. Dermatol."},{"key":"ref22\/cit22","doi-asserted-by":"crossref","first-page":"4211","DOI":"10.1016\/S0021-9258(19)69420-2","volume":"256","author":"Andrews P. C.","year":"1981","journal-title":"J. Biol. Chem."},{"key":"ref23\/cit23","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1016\/j.phymed.2005.03.006","volume":"13","author":"Reininger E. A.","year":"2006","journal-title":"Phytomedicine"},{"key":"ref24\/cit24","doi-asserted-by":"crossref","first-page":"904","DOI":"10.1055\/s-2004-832614","volume":"70","author":"Adams M.","year":"2004","journal-title":"Planta Med."},{"key":"ref25\/cit25","doi-asserted-by":"crossref","first-page":"988","DOI":"10.1016\/j.phytochem.2007.10.013","volume":"69","author":"Kn\u00f6dler M.","year":"2008","journal-title":"Phytochemistry"},{"key":"ref26\/cit26","doi-asserted-by":"crossref","first-page":"975","DOI":"10.1124\/jpet.108.139444","volume":"326","author":"Koeberle A.","year":"2008","journal-title":"J. Pharmacol. Exper. Ther."}],"container-title":["Journal of Natural Products"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/np200343t","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,15]],"date-time":"2023-04-15T23:56:25Z","timestamp":1681602985000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/np200343t"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,7,29]]},"references-count":26,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2011,8,26]]}},"alternative-id":["10.1021\/np200343t"],"URL":"https:\/\/doi.org\/10.1021\/np200343t","relation":{},"ISSN":["0163-3864","1520-6025"],"issn-type":[{"value":"0163-3864","type":"print"},{"value":"1520-6025","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,7,29]]}}}