{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,14]],"date-time":"2026-01-14T14:21:11Z","timestamp":1768400471357,"version":"3.49.0"},"reference-count":28,"publisher":"American Chemical Society (ACS)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Nat. Prod."],"published-print":{"date-parts":[[2013,3,22]]},"DOI":"10.1021\/np300663v","type":"journal-article","created":{"date-parts":[[2012,11,12]],"date-time":"2012-11-12T20:11:02Z","timestamp":1352751062000},"page":"316-321","source":"Crossref","is-referenced-by-count":39,"title":["Curcuminoids Block TGF-\u03b2 Signaling in Human Breast Cancer Cells and Limit Osteolysis in a Murine Model of Breast Cancer Bone Metastasis"],"prefix":"10.1021","volume":"76","author":[{"given":"Laura E.","family":"Wright","sequence":"first","affiliation":[{"name":"Endocrinology\rSection, Department of Medicine, The University of Arizona, Tucson, Arizona 85724, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jennifer B.","family":"Frye","sequence":"additional","affiliation":[{"name":"Endocrinology\rSection, Department of Medicine, The University of Arizona, Tucson, Arizona 85724, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ashley L.","family":"Lukefahr","sequence":"additional","affiliation":[{"name":"Endocrinology\rSection, Department of Medicine, The University of Arizona, Tucson, Arizona 85724, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Barbara N.","family":"Timmermann","sequence":"additional","affiliation":[{"name":"Department of Medicinal Chemistry, School of Pharmacy, The University of Kansas, Kansas 66045, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Khalid S.","family":"Mohammad","sequence":"additional","affiliation":[{"name":"Division of Endocrinology, Department\rof Medicine, Indiana University, Indianapolis,\rIndiana\r46202, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Theresa A.","family":"Guise","sequence":"additional","affiliation":[{"name":"Division of Endocrinology, Department\rof Medicine, Indiana University, Indianapolis,\rIndiana\r46202, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Janet L.","family":"Funk","sequence":"additional","affiliation":[{"name":"Endocrinology\rSection, Department of Medicine, The University of Arizona, Tucson, Arizona 85724, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"316","published-online":{"date-parts":[[2012,11,12]]},"reference":[{"key":"ref1\/cit1","first-page":"1","volume":"23","author":"Hortobagyi G. N.","year":"1996","journal-title":"Semin. Oncol."},{"key":"ref2\/cit2","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1038\/nrc3055","volume":"11","author":"Wielbaecher K. N.","year":"2011","journal-title":"Nat. Rev. Cancer"},{"key":"ref3\/cit3","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1111\/j.1749-6632.2009.05429.x","volume":"1198","author":"Jimenez-Andrade J. M.","year":"2010","journal-title":"Ann. N.Y. Acad. Sci."},{"key":"ref4\/cit4","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1038\/nrc867","volume":"2","author":"Mundy G. R.","year":"2002","journal-title":"Nat. Rev. Cancer"},{"key":"ref5\/cit5","doi-asserted-by":"crossref","first-page":"1544","DOI":"10.1172\/JCI118947","volume":"98","author":"Guise T. A.","year":"1996","journal-title":"J. Clin. Invest."},{"issue":"12","key":"ref6\/cit6","doi-asserted-by":"crossref","first-page":"2892","DOI":"10.1002\/1097-0142(20000615)88:12+<2892::AID-CNCR2>3.0.CO;2-Y","volume":"88","author":"Guise T. A.","year":"2000","journal-title":"Cancer"},{"key":"ref7\/cit7","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1172\/JCI3312","volume":"103","author":"Yin J.","year":"1999","journal-title":"J. Clin. Invest."},{"key":"ref8\/cit8","doi-asserted-by":"crossref","first-page":"13909","DOI":"10.1073\/pnas.0506517102","volume":"102","author":"Kang Y.","year":"2005","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"ref9\/cit9","doi-asserted-by":"crossref","first-page":"E435","DOI":"10.1152\/ajpendo.00143.2002","volume":"284","author":"MacLeod R. J.","year":"2003","journal-title":"Am. J. Physiol. Endocrinol. Metab."},{"key":"ref10\/cit10","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1007\/s12079-011-0117-3","volume":"5","author":"Hussein O.","year":"2011","journal-title":"J. Cell Commun. Signal."},{"key":"ref11\/cit11","doi-asserted-by":"crossref","first-page":"4655","DOI":"10.1172\/JCI46134","volume":"121","author":"Li J.","year":"2011","journal-title":"J. Clin. Invest."},{"key":"ref12\/cit12","doi-asserted-by":"crossref","first-page":"1362","DOI":"10.1172\/JCI728","volume":"101","author":"Funk J. L.","year":"1998","journal-title":"J. Clin. Invest."},{"key":"ref13\/cit13","doi-asserted-by":"crossref","first-page":"1721","DOI":"10.1002\/art.10985","volume":"48","author":"Funk J. L.","year":"2003","journal-title":"Arthritis Rheum."},{"key":"ref14\/cit14","doi-asserted-by":"crossref","first-page":"3452","DOI":"10.1002\/art.22180","volume":"54","author":"Funk J. L.","year":"2006","journal-title":"Arthritis Rheum."},{"key":"ref15\/cit15","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1021\/np050327j","volume":"69","author":"Funk J. L.","year":"2006","journal-title":"J. Nat. Prod."},{"key":"ref16\/cit16","doi-asserted-by":"crossref","first-page":"9498","DOI":"10.1021\/jf101873f","volume":"8","author":"Wright L. E.","year":"2010","journal-title":"J. Agric. Food Chem."},{"key":"ref17\/cit17","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1186\/1472-6882-12-S1-P55","volume":"12","author":"Frye J. B.","year":"2012","journal-title":"BMC Complementary Altern. Med."},{"key":"ref18\/cit18","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1186\/1472-6874-7-4","volume":"7","author":"Boon H. S.","year":"2007","journal-title":"BMC Womens Health"},{"key":"ref19\/cit19","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1089\/acm.2007.03-9040","volume":"13","author":"Matthews A. K.","year":"2007","journal-title":"J. Altern. Complementary Med."},{"key":"ref20\/cit20","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1124\/jpet.108.137455","volume":"326","author":"Begum A. N.","year":"2008","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"ref21\/cit21","doi-asserted-by":"crossref","first-page":"1411","DOI":"10.1158\/1055-9965.EPI-07-2693","volume":"17","author":"Vareed S. K.","year":"2008","journal-title":"Cancer Epidemiol. Biomarkers Prev."},{"key":"ref22\/cit22","doi-asserted-by":"crossref","first-page":"24571","DOI":"10.1074\/jbc.M202561200","volume":"277","author":"Kakonen S. M.","year":"2002","journal-title":"J. Biol. Chem."},{"key":"ref23\/cit23","doi-asserted-by":"crossref","first-page":"46661","DOI":"10.1074\/jbc.M105816200","volume":"276","author":"Lindemann R. K.","year":"2001","journal-title":"J. Biol. Chem."},{"key":"ref24\/cit24","first-page":"799","volume":"22","author":"Lindemann R. K.","year":"2003","journal-title":"Int. J. Oncol."},{"key":"ref25\/cit25","doi-asserted-by":"crossref","first-page":"L616","DOI":"10.1152\/ajplung.00002.2009","volume":"5","author":"Smith M. R.","year":"2010","journal-title":"Am. J. Physiol. Lung Cell Mol. Physiol."},{"key":"ref26\/cit26","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1159\/000287230","volume":"31","author":"Hu Y.","year":"2010","journal-title":"Am. J. Nephrol."},{"key":"ref27\/cit27","doi-asserted-by":"crossref","first-page":"2235","DOI":"10.1016\/j.febslet.2011.05.043","volume":"585","author":"Semsri S.","year":"2011","journal-title":"FEBS Lett."},{"key":"ref28\/cit28","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/j.abb.2011.06.010","volume":"513","author":"Perez-Lara A.","year":"2011","journal-title":"Arch. Biochem. Biophys."}],"container-title":["Journal of Natural Products"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/np300663v","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,22]],"date-time":"2023-04-22T08:54:20Z","timestamp":1682153660000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/np300663v"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,11,12]]},"references-count":28,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2013,3,22]]}},"alternative-id":["10.1021\/np300663v"],"URL":"https:\/\/doi.org\/10.1021\/np300663v","relation":{},"ISSN":["0163-3864","1520-6025"],"issn-type":[{"value":"0163-3864","type":"print"},{"value":"1520-6025","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,11,12]]}}}