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Mounier 73, UCL-CMFA 7340, B-1200 Bruxelles, Belgium, Laboratoire de Chimie Mol\u00e9culaire Structurale, Facult\u00e9 des Sciences, Facult\u00e9s Universitaires Notre Dame de la Paix, Rue de Bruxelles, 61, 5000 Namur, Belgium, Department of Inorganic and Analytical Chemistry, University of Jena, August-Bebel-Strasse 2, 07743 Jena, Germany, and Department of Pharmaceutical Chemistry,..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johan","family":"Wouters","sequence":"additional","affiliation":[{"name":"Unit\u00e9 de Chimie Pharmaceutique et de Radiopharmacie, Ecole de Pharmacie, Facult\u00e9 de M\u00e9decine, Universit\u00e9 catholique de Louvain, Avenue E. 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Mounier 73, UCL-CMFA 7340, B-1200 Bruxelles, Belgium, Laboratoire de Chimie Mol\u00e9culaire Structurale, Facult\u00e9 des Sciences, Facult\u00e9s Universitaires Notre Dame de la Paix, Rue de Bruxelles, 61, 5000 Namur, Belgium, Department of Inorganic and Analytical Chemistry, University of Jena, August-Bebel-Strasse 2, 07743 Jena, Germany, and Department of Pharmaceutical Chemistry,..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Didier M.","family":"Lambert","sequence":"additional","affiliation":[{"name":"Unit\u00e9 de Chimie Pharmaceutique et de Radiopharmacie, Ecole de Pharmacie, Facult\u00e9 de M\u00e9decine, Universit\u00e9 catholique de Louvain, Avenue E. 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G.","year":"2003","journal-title":"Tetrahedron"},{"key":"ol035282xb00002\/ol035282xb00002_1","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1016\/S0040-4039(00)83996-9","volume":"27","author":"Gedye R.","year":"1986","journal-title":"Tetrahedron Lett."},{"key":"ol035282xb00002\/ol035282xb00002_2","first-page":"26","volume":"66","author":"Gedye R.","year":"1987","journal-title":"Can. J. Chem."},{"key":"ol035282xb00003\/ol035282xb00003_1","doi-asserted-by":"crossref","first-page":"4948","DOI":"10.1016\/S0040-4039(00)85103-5","volume":"27","author":"Giguere R. J.","year":"1986","journal-title":"Tetrahedron Lett."},{"key":"ol035282xb00004\/ol035282xb00004_1","first-page":"416","volume":"6","author":"Two","year":"2001","journal-title":"Drug Discovery Today"},{"key":"ol035282xb00005\/ol035282xb00005_1","first-page":"1803","volume":"10","author":"Kappe O. 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K.","year":"1992","journal-title":"Tetrahedron Lett."},{"key":"ol035282xb00006\/ol035282xb00006_3","first-page":"6992","volume":"37","author":"Bose A. K.","year":"1996","journal-title":"Tetrahedron Lett."},{"key":"ol035282xb00006\/ol035282xb00006_4","first-page":"1591","volume":"1578","author":"Bose A. K.","year":"2002","journal-title":"Synthesis"},{"key":"ol035282xb00008\/ol035282xb00008_1","first-page":"501","volume":"4","author":"Henneuse C.","year":"1996","journal-title":"Synthesis"},{"key":"ol035282xb00009\/ol035282xb00009_1","first-page":"122","volume":"59","author":"Schramm H. W.","year":"1991","journal-title":"Sci. Pharm."},{"key":"ol035282xb00010\/ol035282xb00010_1","unstructured":"General Procedure for the Microwave-Assisted Method.To a solution of 3 g of benzil (14.3 mmol) and 1.94 g of phenylurea (28.6 mmol) in 25 mL of DMSO was added 25 mL of 1.2 M aqueous KOH under stirring. Following an initial 90 s, 750W microwave irradiation, the mixture was stirred for 5 min. Additional 30 s pulses were applied at 6, 9, 12, 15, 18, 21, 24, 30 min. Between pulses the mixture was stirred. After the completion of the sequence, the mixture was poured onto cold water, the resulting precipitate was filtered, dried, and recrystallized from a suitable solvent. All microwave irradiations were carried out in an open system."},{"key":"ol035282xb00011\/ol035282xb00011_1","unstructured":"General Procedure for the Classical Method.As used for9, but the reacting mixture was refluxed over a period of 4 h instead of receiving the microwave pulse sequence."},{"key":"ol035282xb00012\/ol035282xb00012_1","first-page":"744","volume":"30","author":"Bose A. K.","year":"1990","journal-title":"Heterocycles"},{"key":"ol035282xb00014\/ol035282xb00014_1","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1021\/ed060p512","volume":"60","author":"Hayward R. C.","year":"1983","journal-title":"J. Chem. 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