{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,27]],"date-time":"2026-04-27T00:44:55Z","timestamp":1777250695218,"version":"3.51.4"},"reference-count":18,"publisher":"American Chemical Society (ACS)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Org. Lett."],"published-print":{"date-parts":[[2005,1,1]]},"DOI":"10.1021\/ol047647z","type":"journal-article","created":{"date-parts":[[2005,1,13]],"date-time":"2005-01-13T06:24:39Z","timestamp":1105597479000},"page":"327-329","source":"Crossref","is-referenced-by-count":89,"title":["Cross-Linked Aggregates of (<i>R<\/i>)-Oxynitrilase:\u2009 A Stable, Recyclable Biocatalyst for Enantioselective Hydrocyanation"],"prefix":"10.1021","volume":"7","author":[{"given":"Luuk M.","family":"van Langen","sequence":"first","affiliation":[{"name":"Laboratory of Biocatalysis and Organic Chemistry, Delft University of Technology, Julianalaan 136, 2628 BL Delft, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rhoderick P.","family":"Selassa","sequence":"additional","affiliation":[{"name":"Laboratory of Biocatalysis and Organic Chemistry, Delft University of Technology, Julianalaan 136, 2628 BL Delft, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fred","family":"van Rantwijk","sequence":"additional","affiliation":[{"name":"Laboratory of Biocatalysis and Organic Chemistry, Delft University of Technology, Julianalaan 136, 2628 BL Delft, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roger A.","family":"Sheldon","sequence":"additional","affiliation":[{"name":"Laboratory of Biocatalysis and Organic Chemistry, Delft University of Technology, Julianalaan 136, 2628 BL Delft, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"316","published-online":{"date-parts":[[2004,12,23]]},"reference":[{"key":"ol047647zb00001\/ol047647zb00001_1","first-page":"320","volume-title":"Valuable Building Blocks in Organic Synthesis. In Stereoselective Biocatalysis","author":"Brussee J.","year":"2000"},{"key":"ol047647zb00002\/ol047647zb00002_1","first-page":"342","volume-title":"Stereoselective Biocatalysis","author":"Effenberger F.","year":"2000"},{"key":"ol047647zb00003\/ol047647zb00003_1","first-page":"226","volume":"200","author":"Schmidt M.","year":"1999","journal-title":"Top. Curr. Chem."},{"key":"ol047647zb00004\/ol047647zb00004_1","first-page":"266","volume":"12","author":"Loos W. T.","year":"1995","journal-title":"Biocatal. Biotransform."},{"key":"ol047647zb00005\/ol047647zb00005_1","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1002\/anie.199003861","volume":"29","author":"Niedermeyer U.","year":"1990","journal-title":"Angew. Chem., Int. Ed. Engl."},{"key":"ol047647zb00006\/ol047647zb00006_1","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1016\/S0141-0229(01)00467-7","volume":"30","author":"Willeman W. K.","year":"2002","journal-title":"J. Enzyme Microb. Technol."},{"key":"ol047647zb00007\/ol047647zb00007_1","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1002\/bit.10002","volume":"77","author":"Willeman W. F.","year":"2002","journal-title":"J. Biotechnol. Bioeng."},{"key":"ol047647zb00008\/ol047647zb00008_1","doi-asserted-by":"crossref","first-page":"1391","DOI":"10.1080\/00397919108021286","volume":"21","author":"Zandbergen P.","year":"1991","journal-title":"Synth. Commun."},{"key":"ol047647zb00009\/ol047647zb00009_1","doi-asserted-by":"crossref","unstructured":"Kiljunen, E.; Kanerva, L. T.Tetrahedron:\u2009 Asymmetry1996,7, 1105\u22121116.","DOI":"10.1016\/0957-4166(96)00116-4"},{"key":"ol047647zb00010\/ol047647zb00010_1","doi-asserted-by":"crossref","unstructured":"Lin, G.; Han, S.; Li, Z.Tetrahedron:\u2009 Asymmetry1998,9, 1835\u22121838.","DOI":"10.1016\/S0957-4166(98)00177-3"},{"key":"ol047647zb00011\/ol047647zb00011_1","doi-asserted-by":"crossref","first-page":"831","DOI":"10.1021\/op0340964","volume":"7","author":"Van Langen L. M.","year":"2003","journal-title":"Org. Proc. Res. Dev."},{"key":"ol047647zb00012\/ol047647zb00012_1","first-page":"45292u","volume":"135","author":"P\u00f6chlauer P.","year":"2001","journal-title":"Chem. Abstr."},{"key":"ol047647zb00013\/ol047647zb00013_1","first-page":"1364","volume":"2","author":"Cao L.","year":"2000","journal-title":"Org. Lett."},{"key":"ol047647zb00014\/ol047647zb00014_1","doi-asserted-by":"crossref","first-page":"762","DOI":"10.1002\/bit.20184","volume":"87","author":"Schoevaart R.","year":"2004","journal-title":"Biotechnol. Bioeng."},{"key":"ol047647zb00015\/ol047647zb00015_1","first-page":"432","volume":"78","author":"Janssen M. H. A.","year":"2002","journal-title":"Biotechnol. Bioeng."},{"key":"ol047647zb00016\/ol047647zb00016_1","doi-asserted-by":"crossref","first-page":"6499","DOI":"10.1016\/S0040-4020(00)00617-7","volume":"56","author":"Herold P.","year":"2000","journal-title":"Tetrahedron"},{"key":"ol047647zb00017\/ol047647zb00017_1","volume-title":"Lecture presented at the 6th International Symposium on Catalysis Applied to Fine Chemicals","author":"Glieder A."},{"key":"ol047647zb00018\/ol047647zb00018_1","first-page":"24","volume":"115","author":"Warmerdam E. G. J. C.","year":"1996","journal-title":"Recl. Trav. Chim. Pays-Bas"}],"container-title":["Organic Letters"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/ol047647z","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,3,23]],"date-time":"2023-03-23T20:22:10Z","timestamp":1679602930000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/ol047647z"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,12,23]]},"references-count":18,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2005,1,1]]}},"alternative-id":["10.1021\/ol047647z"],"URL":"https:\/\/doi.org\/10.1021\/ol047647z","relation":{},"ISSN":["1523-7060","1523-7052"],"issn-type":[{"value":"1523-7060","type":"print"},{"value":"1523-7052","type":"electronic"}],"subject":[],"published":{"date-parts":[[2004,12,23]]}}}