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Chem."},{"key":"ref2\/cit2","doi-asserted-by":"crossref","first-page":"1546","DOI":"10.1002\/anie.198815461","volume":"27","author":"Barluenga J.","year":"1988","journal-title":"Angew. Chem., Int. Ed."},{"key":"ref3\/cit3","unstructured":"For selected references, see:"},{"key":"ref3\/cit3a","doi-asserted-by":"crossref","first-page":"12230","DOI":"10.1021\/ja053079m","volume":"127","author":"Zhang X.","year":"2005","journal-title":"J. Am. Chem. Soc."},{"key":"ref3\/cit3b","doi-asserted-by":"crossref","first-page":"2008","DOI":"10.1039\/B500303B","author":"Barluenga J.","year":"2005","journal-title":"Chem. Commun."},{"key":"ref3\/cit3c","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1021\/jo051948k","volume":"71","author":"Zhang X.","year":"2006","journal-title":"J. Org. Chem."},{"key":"ref3\/cit3d","doi-asserted-by":"crossref","first-page":"1437","DOI":"10.1021\/jo062234s","volume":"72","author":"Worlikar S. A.","year":"2007","journal-title":"J. Org. Chem."},{"key":"ref3\/cit3e","doi-asserted-by":"crossref","first-page":"1063","DOI":"10.1021\/ol703050z","volume":"10","author":"Tang B.-X.","year":"2008","journal-title":"Org. Lett."},{"key":"ref3\/cit3f","doi-asserted-by":"crossref","first-page":"4759","DOI":"10.1016\/j.tetlet.2009.06.015","volume":"50","author":"Rahman M. A.","year":"2009","journal-title":"Tetrahedron Lett."},{"key":"ref4\/cit4a","doi-asserted-by":"crossref","first-page":"3106","DOI":"10.1021\/jo00063a033","volume":"58","author":"Kitagawa O.","year":"1993","journal-title":"J. Org. Chem."},{"key":"ref4\/cit4b","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1021\/ol062683e","volume":"9","author":"Bi H.-P.","year":"2007","journal-title":"Org. Lett."},{"key":"ref4\/cit4c","doi-asserted-by":"crossref","first-page":"2823","DOI":"10.1021\/ol0710459","volume":"9","author":"Barluenga J.","year":"2007","journal-title":"Org. Lett."},{"key":"ref4\/cit4d","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1021\/ol8024956","volume":"11","author":"Ali Z.","year":"2009","journal-title":"Org. Lett."},{"key":"ref5\/cit5a","doi-asserted-by":"crossref","first-page":"6075","DOI":"10.1002\/ejoc.200900790","volume":"35","author":"Belmont P.","year":"2009","journal-title":"Eur. J. Org. Chem."},{"key":"ref5\/cit5b","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1039\/B812466C","author":"Lee S. I.","year":"2009","journal-title":"Chem. Commun."},{"key":"ref5\/cit5c","doi-asserted-by":"crossref","first-page":"3326","DOI":"10.1021\/cr0684319","volume":"108","author":"Jimenez-Nunez E.","year":"2008","journal-title":"Chem. Rev."},{"key":"ref5\/cit5d","doi-asserted-by":"crossref","first-page":"3351","DOI":"10.1021\/cr068430g","volume":"108","author":"Gorin D. J.","year":"2008","journal-title":"Chem. Rev."},{"key":"ref5\/cit5e","first-page":"7427","volume":"45","author":"Michelet V.","year":"2008","journal-title":"Angew. Chem., Int. Ed."},{"key":"ref5\/cit5f","doi-asserted-by":"crossref","first-page":"3410","DOI":"10.1002\/anie.200604335","volume":"46","author":"F\u00fcrstner A.","year":"2007","journal-title":"Angew. Chem., Int. Ed."},{"key":"ref6\/cit6","unstructured":"For a recent review and seminal examples:"},{"key":"ref6\/cit6a","doi-asserted-by":"crossref","first-page":"5075","DOI":"10.1039\/b909978f","author":"Yamamoto Y.","year":"2009","journal-title":"Chem. Commun."},{"key":"ref7\/cit7","unstructured":"For recent examples of iodonium-mediated6-endo-digcycloisomerization of 1,5-enynes, see:"},{"key":"ref7\/cit7a","first-page":"368","author":"Lim C.","year":"2010","journal-title":"Synlett"},{"key":"ref7\/cit7b","doi-asserted-by":"crossref","first-page":"4661","DOI":"10.1002\/anie.201001113","volume":"49","author":"Crone B.","year":"2010","journal-title":"Angew. Chem., Int. Ed."},{"key":"ref8\/cit8","unstructured":"For a recent paper, which appeared during the submission process:"},{"key":"ref8\/cit8a","doi-asserted-by":"crossref","first-page":"7427","DOI":"10.1039\/c0cc02590a","volume":"46","author":"Sanz R.","year":"2010","journal-title":"Chem. Commun."},{"key":"ref8\/cit8b","unstructured":"For a single example using Br2, see:"},{"key":"ref8\/cit8c","doi-asserted-by":"crossref","first-page":"5757","DOI":"10.1002\/anie.200351195","volume":"42","author":"Schreiner P. R.","year":"2003","journal-title":"Angew. Chem., Int. Ed."},{"key":"ref9\/cit9","unstructured":"For Hg- Pt- and Au-catalyzed carbocyclization of 1,5-enynes, see:"},{"key":"ref9\/cit9a","first-page":"703","author":"Imagawa H.","year":"2005","journal-title":"Synlett"},{"key":"ref9\/cit9b","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1021\/ol047472t","volume":"7","author":"Imagawa H.","year":"2005","journal-title":"Org. Lett."},{"key":"ref9\/cit9c","doi-asserted-by":"crossref","first-page":"6962","DOI":"10.1021\/ja051110e","volume":"127","author":"Zhang L.","year":"2005","journal-title":"J. Am. Chem. Soc."},{"key":"ref9\/cit9d","doi-asserted-by":"crossref","first-page":"5991","DOI":"10.1002\/anie.200602035","volume":"45","author":"Staben S. T.","year":"2006","journal-title":"Angew. Chem., Int. Ed."},{"key":"ref9\/cit9e","doi-asserted-by":"crossref","first-page":"1141","DOI":"10.1002\/anie.200604140","volume":"46","author":"Buzas A. K.","year":"2007","journal-title":"Angew. Chem., Int. Ed."},{"key":"ref9\/cit9f","doi-asserted-by":"crossref","first-page":"950","DOI":"10.1021\/om801069s","volume":"28","author":"Nelsen D. L.","year":"2009","journal-title":"Organometallics"},{"key":"ref9\/cit9g","doi-asserted-by":"crossref","first-page":"2888","DOI":"10.1021\/ol900864n","volume":"11","author":"Toullec P. Y.","year":"2009","journal-title":"Org. Lett."},{"key":"ref9\/cit9h","doi-asserted-by":"crossref","first-page":"4633","DOI":"10.1002\/anie.201001089","volume":"49","author":"Martinez A.","year":"2010","journal-title":"Angew. Chem., Int. Ed."},{"key":"ref9\/cit9hh","unstructured":"For a W-catalyzed example of 5-endocyclization, see:"},{"key":"ref9\/cit9i","doi-asserted-by":"crossref","first-page":"4463","DOI":"10.1021\/ol026993i","volume":"4","author":"Iwasawa N.","year":"2002","journal-title":"Org. Lett."},{"key":"ref10\/cit10","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1021\/jo00150a029","volume":"48","author":"Uemura S.","year":"1983","journal-title":"J. Org. Chem."},{"key":"ref11\/cit11","unstructured":"In the case of iodine and ICl, the use of an additional base, e.g., K3PO4,(3a)did not lead to any improvement of the yield."},{"key":"ref12\/cit12","unstructured":"For the reactivity of the ene-ynamide mediated by electrophilic oxene transfer reagents, see:"},{"key":"ref12\/cit12a","first-page":"2819","author":"Couty S.","year":"2007","journal-title":"Synlett"},{"key":"ref12\/cit12b","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1021\/ol703083k","volume":"10","author":"Al-Rashid Z. F.","year":"2008","journal-title":"Org. Lett."},{"key":"ref13\/cit13","unstructured":"The reactivity of 1,5-enyne bearing an electron-deficient aryl group on the alkyne moiety was sluggish, and traces of the desired product were detected."},{"key":"ref14\/cit14","unstructured":"For iodine-mediated PMB deprotection, see:"},{"key":"ref14\/cit14a","doi-asserted-by":"crossref","first-page":"1157","DOI":"10.1055\/s-1995-5213","author":"Vaino A. R.","year":"1995","journal-title":"Synlett"},{"key":"ref15\/cit15","unstructured":"For the iodine-mediated formation of bicyclic spiro structures, see:"},{"key":"ref15\/cit15a","unstructured":"aRef3a."},{"key":"ref15\/cit15b","unstructured":"Ref3c."},{"key":"ref15\/cit15c","first-page":"203","author":"Okitsu T.","year":"2010","journal-title":"Synlett"}],"container-title":["Organic Letters"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/ol102257z","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,5]],"date-time":"2023-04-05T00:55:10Z","timestamp":1680656110000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/ol102257z"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,10,28]]},"references-count":54,"journal-issue":{"issue":"22","published-print":{"date-parts":[[2010,11,19]]}},"alternative-id":["10.1021\/ol102257z"],"URL":"https:\/\/doi.org\/10.1021\/ol102257z","relation":{},"ISSN":["1523-7060","1523-7052"],"issn-type":[{"value":"1523-7060","type":"print"},{"value":"1523-7052","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,10,28]]}}}