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Based on its mechanistic bifurcation after convergent C\u2013N bond formation, depending on the absence or presence of oxygen, UmAS using substoichiometric N-iodosuccinimide (NIS) under aerobic conditions has been developed. In combination with the enantioselective preparation of \u03b1-bromo nitroalkane donors, this protocol realizes the goal of enantioselective \u03b1-amino amide and peptide synthesis based solely on catalytic methods.<\/jats:p>","DOI":"10.1021\/ol502089v","type":"journal-article","created":{"date-parts":[[2014,9,8]],"date-time":"2014-09-08T15:15:54Z","timestamp":1410189354000},"page":"4714-4717","source":"Crossref","is-referenced-by-count":44,"title":["Umpolung Amide Synthesis Using Substoichiometric\n                    <i>N<\/i>\n                    -Iodosuccinimide (NIS) and Oxygen as a Terminal\nOxidant"],"prefix":"10.1021","volume":"16","author":[{"given":"Kenneth E.","family":"Schwieter","sequence":"first","affiliation":[{"name":"Vanderbilt University , , , ,","place":["Nashville, Tennessee, United States, 37235"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bo","family":"Shen","sequence":"additional","affiliation":[{"name":"Vanderbilt University , , , ,","place":["Nashville, Tennessee, United States, 37235"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jessica P.","family":"Shackleford","sequence":"additional","affiliation":[{"name":"Vanderbilt University , , , ,","place":["Nashville, Tennessee, United States, 37235"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew W.","family":"Leighty","sequence":"additional","affiliation":[{"name":"Vanderbilt University , , , ,","place":["Nashville, Tennessee, United States, 37235"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffrey N.","family":"Johnston","sequence":"additional","affiliation":[{"name":"Vanderbilt University , , , ,","place":["Nashville, Tennessee, United States, 37235"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2014,9,8]]},"reference":[{"key":"2026090222465855400_cit1","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1039\/B703488C","volume":"9","author":"Constable","year":"2007","journal-title":"Green Chem."},{"key":"2026090222465855400_cit2a","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1038\/nature10702","volume":"480","author":"Pattabiraman","year":"2011","journal-title":"Nature"},{"key":"2026090222465855400_cit2b","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1146\/annurev.biophys.34.040204.144700","volume":"34","author":"Nilsson","year":"2005","journal-title":"Annu. 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