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Mass Spectrom."},{"key":"ref24\/cit24","doi-asserted-by":"crossref","first-page":"1736","DOI":"10.1016\/j.febslet.2009.03.029","volume":"583","author":"Calvete J. J.","year":"2009","journal-title":"FEBS Lett."},{"key":"ref25\/cit25","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/j.jprot.2009.01.008","volume":"72","author":"Guti\u00e9rrez J. M.","year":"2009","journal-title":"J. Proteomics"},{"key":"ref26\/cit26","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/0041-0101(94)90087-6","volume":"32","author":"Rojas G.","year":"1994","journal-title":"Toxicon"},{"key":"ref27\/cit27","doi-asserted-by":"crossref","first-page":"887","DOI":"10.1016\/0041-0101(85)90380-0","volume":"23","author":"Guti\u00e9rrez J. M.","year":"1985","journal-title":"Toxicon"},{"key":"ref28\/cit28","first-page":"949","volume":"61","author":"Theakston R. D. G.","year":"1983","journal-title":"Bull. 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Latinoam."},{"key":"ref39\/cit39","first-page":"269","volume-title":"Venom Phospholipase A2 Enzymes: Structure, Function and Mechanism","author":"Bon C.","year":"1997"},{"key":"ref40\/cit40","doi-asserted-by":"crossref","first-page":"1045","DOI":"10.1016\/j.toxicon.2010.01.011","volume":"55","author":"Sampaio S. C.","year":"2010","journal-title":"Toxicon"},{"key":"ref41\/cit41","doi-asserted-by":"crossref","first-page":"1076","DOI":"10.1002\/cber.19380710527","volume":"71","author":"Slotta K.","year":"1938","journal-title":"Ber. Dtsch. Chem. Ges."},{"key":"ref42\/cit42","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/0378-1119(94)90761-7","volume":"139","author":"John T. R.","year":"1994","journal-title":"Gene"},{"key":"ref43\/cit43","doi-asserted-by":"crossref","first-page":"781","DOI":"10.1016\/j.toxicon.2004.08.008","volume":"44","author":"French W. 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