{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T21:24:07Z","timestamp":1791321847263,"version":"4.3.1"},"reference-count":51,"publisher":"American Chemical Society (ACS)","issue":"7","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Proteome Res."],"published-print":{"date-parts":[[2013,7,5]]},"DOI":"10.1021\/pr4003068","type":"journal-article","created":{"date-parts":[[2013,6,3]],"date-time":"2013-06-03T11:47:17Z","timestamp":1370260037000},"page":"3460-3470","source":"Crossref","is-referenced-by-count":57,"title":["Moving Pieces in a Venomic Puzzle: Unveiling Post-translationally Modified Toxins from <i>Tityus serrulatus<\/i>"],"prefix":"10.1021","volume":"12","author":[{"given":"Thiago","family":"Verano-Braga","sequence":"first","affiliation":[{"name":"Department of Biochemistry and\rMolecular Biology, University of Southern Denmark, Odense, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandre A. A.","family":"Dutra","sequence":"additional","affiliation":[{"name":"Department\rof Biochemistry and\rImmunology, Federal University of Minas Gerais, Belo Horizonte-MG, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ileana R.","family":"Le\u00f3n","sequence":"additional","affiliation":[{"name":"Department of Biochemistry and\rMolecular Biology, University of Southern Denmark, Odense, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcella N.","family":"Melo-Braga","sequence":"additional","affiliation":[{"name":"Department of Biochemistry and\rMolecular Biology, University of Southern Denmark, Odense, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Roepstorff","sequence":"additional","affiliation":[{"name":"Department of Biochemistry and\rMolecular Biology, University of Southern Denmark, Odense, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adriano M. C.","family":"Pimenta","sequence":"additional","affiliation":[{"name":"Department\rof Biochemistry and\rImmunology, Federal University of Minas Gerais, Belo Horizonte-MG, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frank","family":"Kjeldsen","sequence":"additional","affiliation":[{"name":"Department of Biochemistry and\rMolecular Biology, University of Southern Denmark, Odense, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2013,6,13]]},"reference":[{"issue":"1","key":"ref1\/cit1","first-page":"154","volume":"27","author":"Lourenco W. R.","year":"1999","journal-title":"J. Arachnol."},{"key":"ref2\/cit2","unstructured":"Ministerio-da-Saude Acidentes por animais pe\u00e7onhentos \u2013 Escorpi\u00f5es. Aspectos edpidemiol\u00f3gicos.http:\/\/portal.saude.gov.br\/portal\/saude\/profissional\/area.cfm?id_area=1537"},{"issue":"5","key":"ref3\/cit3","doi-asserted-by":"crossref","first-page":"411","DOI":"10.2174\/187152811797200614","volume":"10","author":"Rates B.","year":"2011","journal-title":"Inflamm. Allergy Drug Targets"},{"issue":"11","key":"ref4\/cit4","doi-asserted-by":"crossref","first-page":"670","DOI":"10.1002\/psc.701","volume":"11","author":"Pimenta A. M.","year":"2005","journal-title":"J. Pept. Sci."},{"issue":"4","key":"ref5\/cit5","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1016\/j.toxicon.2012.03.024","volume":"60","author":"Jimenez-Vargas J. M.","year":"2012","journal-title":"Toxicon"},{"key":"ref6\/cit6","doi-asserted-by":"crossref","first-page":"624","DOI":"10.1016\/S0076-6879(99)94035-1","volume":"294","author":"Garcia M. L.","year":"1999","journal-title":"Methods Enzymol."},{"issue":"2","key":"ref7\/cit7","doi-asserted-by":"crossref","first-page":"C361","DOI":"10.1152\/ajpcell.1993.264.2.C361","volume":"264","author":"DeBin J. A.","year":"1993","journal-title":"Am. J. Physiol."},{"issue":"9","key":"ref8\/cit8","doi-asserted-by":"crossref","first-page":"861","DOI":"10.1016\/S0300-9084(00)01167-6","volume":"82","author":"Possani L. D.","year":"2000","journal-title":"Biochimie"},{"issue":"9","key":"ref9\/cit9","doi-asserted-by":"crossref","first-page":"883","DOI":"10.1016\/S0300-9084(01)01326-8","volume":"83","author":"Zeng X. C.","year":"2001","journal-title":"Biochimie"},{"issue":"3","key":"ref10\/cit10","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1016\/j.bbrc.2008.04.104","volume":"371","author":"Verano-Braga T.","year":"2008","journal-title":"Biochem. Biophys. Res. Commun."},{"issue":"8","key":"ref11\/cit11","doi-asserted-by":"crossref","first-page":"941","DOI":"10.1016\/0041-0101(93)90253-F","volume":"31","author":"Ferreira L. A.","year":"1993","journal-title":"Toxicon"},{"issue":"7","key":"ref12\/cit12","doi-asserted-by":"crossref","first-page":"1162","DOI":"10.1016\/j.toxicon.2010.04.006","volume":"56","author":"Verano-Braga T.","year":"2010","journal-title":"Toxicon"},{"issue":"2","key":"ref13\/cit13","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1016\/j.peptides.2012.03.016","volume":"35","author":"Almaaytah A.","year":"2012","journal-title":"Peptides"},{"issue":"7","key":"ref14\/cit14","doi-asserted-by":"crossref","first-page":"e40135","DOI":"10.1371\/journal.pone.0040135","volume":"7","author":"Cao L.","year":"2012","journal-title":"PLoS One"},{"issue":"2","key":"ref15\/cit15","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/j.peptides.2012.04.010","volume":"36","author":"Cao L.","year":"2012","journal-title":"Peptides"},{"issue":"17","key":"ref16\/cit16","doi-asserted-by":"crossref","first-page":"1562","DOI":"10.1002\/rcm.415","volume":"15","author":"Pimenta A. M.","year":"2001","journal-title":"Rapid Commun. Mass Spectrom."},{"issue":"9","key":"ref17\/cit17","doi-asserted-by":"crossref","first-page":"861","DOI":"10.1016\/S0300-9084(00)01167-6","volume":"82","author":"Possani L. D.","year":"2000","journal-title":"Biochimie"},{"issue":"8","key":"ref18\/cit18","doi-asserted-by":"crossref","first-page":"865","DOI":"10.1016\/j.toxicon.2004.03.022","volume":"43","author":"Rodriguez de la Vega R. C.","year":"2004","journal-title":"Toxicon"},{"issue":"5","key":"ref19\/cit19","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1016\/j.toxicon.2008.07.010","volume":"52","author":"Rates B.","year":"2008","journal-title":"Toxicon"},{"issue":"1","key":"ref20\/cit20","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/j.jchromb.2003.09.002","volume":"803","author":"Batista C. V.","year":"2004","journal-title":"J. Chromatogr., B Anal. Technol. Biomed. Life Sci."},{"issue":"12","key":"ref21\/cit21","doi-asserted-by":"crossref","first-page":"3718","DOI":"10.1002\/pmic.200500525","volume":"6","author":"Batista C. V.","year":"2006","journal-title":"Proteomics"},{"issue":"12","key":"ref22\/cit22","doi-asserted-by":"crossref","first-page":"e47866","DOI":"10.1371\/journal.pone.0047866","volume":"7","author":"Brinkman D. L.","year":"2012","journal-title":"PLoS One"},{"issue":"5","key":"ref23\/cit23","doi-asserted-by":"crossref","first-page":"1081","DOI":"10.1002\/pmic.200700948","volume":"8","author":"Bringans S.","year":"2008","journal-title":"Proteomics"},{"issue":"2","key":"ref24\/cit24","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/S0014-5793(98)01710-4","volume":"443","author":"Hassani O.","year":"1999","journal-title":"FEBS Lett."},{"issue":"8","key":"ref25\/cit25","doi-asserted-by":"crossref","first-page":"1453","DOI":"10.1111\/j.1432-1033.2004.04047.x","volume":"271","author":"Valdez-Cruz N. A.","year":"2004","journal-title":"Eur. J. Biochem."},{"issue":"5259","key":"ref26\/cit26","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1038\/227680a0","volume":"227","author":"Laemmli U. K.","year":"1970","journal-title":"Nature"},{"issue":"6","key":"ref27\/cit27","doi-asserted-by":"crossref","first-page":"1024","DOI":"10.1002\/elps.1150190618","volume":"19","author":"Nawrocki A.","year":"1998","journal-title":"Electrophoresis"},{"issue":"11","key":"ref28\/cit28","doi-asserted-by":"crossref","first-page":"1191","DOI":"10.1074\/mcp.M112.017509","volume":"11","author":"Palmisano G.","year":"2012","journal-title":"Mol. Cell. Proteomics"},{"issue":"13","key":"ref29\/cit29","doi-asserted-by":"crossref","first-page":"5598","DOI":"10.1021\/ac100530w","volume":"82","author":"Mysling S.","year":"2010","journal-title":"Anal. Chem."},{"issue":"13","key":"ref30\/cit30","doi-asserted-by":"crossref","first-page":"3590","DOI":"10.1021\/ac0497104","volume":"76","author":"Schroeder M. J.","year":"2004","journal-title":"Anal. Chem."},{"issue":"12","key":"ref31\/cit31","doi-asserted-by":"crossref","first-page":"5354","DOI":"10.1021\/pr200611n","volume":"10","author":"Taus T.","year":"2011","journal-title":"J. Proteome Res."},{"issue":"2","key":"ref32\/cit32","doi-asserted-by":"crossref","first-page":"M110 003830","DOI":"10.1074\/mcp.M110.003830","volume":"10","author":"Savitski M. M.","year":"2011","journal-title":"Mol. Cell. Proteomics"},{"issue":"20","key":"ref33\/cit33","doi-asserted-by":"crossref","first-page":"2337","DOI":"10.1002\/rcm.1196","volume":"17","author":"Ma B.","year":"2003","journal-title":"Rapid Commun. Mass Spectrom."},{"issue":"19","key":"ref34\/cit34","doi-asserted-by":"crossref","first-page":"9747","DOI":"10.1016\/S0021-9258(19)83579-2","volume":"254","author":"Hart G. W.","year":"1979","journal-title":"J. Biol. Chem."},{"issue":"4","key":"ref35\/cit35","doi-asserted-by":"crossref","first-page":"M111 010587","DOI":"10.1074\/mcp.M111.010587","volume":"11","author":"Zhang J.","year":"2012","journal-title":"Mol. Cell. Proteomics"},{"issue":"6","key":"ref36\/cit36","doi-asserted-by":"crossref","first-page":"628","DOI":"10.1016\/j.toxicon.2006.01.015","volume":"47","author":"Nascimento D. G.","year":"2006","journal-title":"Toxicon"},{"issue":"10","key":"ref37\/cit37","doi-asserted-by":"crossref","first-page":"1778","DOI":"10.1074\/mcp.M700086-MCP200","volume":"6","author":"Larsen M. R.","year":"2007","journal-title":"Mol. Cell. Proteomics"},{"issue":"11","key":"ref38\/cit38","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1016\/S0165-6147(99)01398-X","volume":"20","author":"Tytgat J.","year":"1999","journal-title":"Trends Pharmacol. Sci."},{"issue":"8","key":"ref39\/cit39","doi-asserted-by":"crossref","first-page":"831","DOI":"10.1016\/j.toxicon.2005.09.006","volume":"46","author":"Rodriguez de la Vega R. C.","year":"2005","journal-title":"Toxicon"},{"issue":"7","key":"ref40\/cit40","doi-asserted-by":"crossref","first-page":"1041","DOI":"10.1016\/S0041-0101(02)00084-3","volume":"40","author":"Almeida F. M.","year":"2002","journal-title":"Toxicon"},{"issue":"1","key":"ref41\/cit41","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/j.cbpc.2006.12.004","volume":"146","author":"Batista C. V.","year":"2007","journal-title":"Comp. Biochem. Physiol. C Toxicol. Pharmacol."},{"issue":"10","key":"ref42\/cit42","doi-asserted-by":"crossref","first-page":"7405","DOI":"10.1074\/jbc.M109.028365","volume":"285","author":"Fletcher P. L.","year":"2010","journal-title":"J. Biol. Chem."},{"issue":"2","key":"ref43\/cit43","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/0014-5793(94)80496-6","volume":"342","author":"Martin-Eauclaire M. F.","year":"1994","journal-title":"FEBS Lett."},{"issue":"2","key":"ref44\/cit44","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1002\/nt.2620010211","volume":"1","author":"Mansuelle P.","year":"1992","journal-title":"Nat. Toxins"},{"issue":"2","key":"ref45\/cit45","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/0378-1119(93)90559-L","volume":"128","author":"Becerril B.","year":"1993","journal-title":"Gene"},{"issue":"2","key":"ref46\/cit46","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1074\/mcp.M500270-MCP200","volume":"5","author":"Birrell G. W.","year":"2006","journal-title":"Mol. Cell. Proteomics"},{"issue":"1","key":"ref47\/cit47","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1016\/j.toxicon.2010.09.009","volume":"57","author":"Kauferstein S.","year":"2011","journal-title":"Toxicon"},{"issue":"5","key":"ref48\/cit48","doi-asserted-by":"crossref","first-page":"1234","DOI":"10.1021\/jm031010o","volume":"47","author":"Loughnan M. L.","year":"2004","journal-title":"J. Med. Chem."},{"issue":"5","key":"ref49\/cit49","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1074\/mcp.M300140-MCP200","volume":"3","author":"Medzihradszky K. F.","year":"2004","journal-title":"Mol. Cell. Proteomics"},{"issue":"1","key":"ref50\/cit50","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/j.toxicon.2011.05.001","volume":"58","author":"Cologna C. T.","year":"2011","journal-title":"Toxicon"},{"issue":"6","key":"ref51\/cit51","doi-asserted-by":"crossref","first-page":"973","DOI":"10.1074\/mcp.M600419-MCP200","volume":"6","author":"Birrell G. W.","year":"2007","journal-title":"Mol. Cell. Proteomics"}],"container-title":["Journal of Proteome Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/pr4003068","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,2]],"date-time":"2023-04-02T16:58:36Z","timestamp":1680454716000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/pr4003068"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,6,13]]},"references-count":51,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2013,7,5]]}},"alternative-id":["10.1021\/pr4003068"],"URL":"https:\/\/doi.org\/10.1021\/pr4003068","relation":{},"ISSN":["1535-3893","1535-3907"],"issn-type":[{"value":"1535-3893","type":"print"},{"value":"1535-3907","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,6,13]]}}}