{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T08:45:23Z","timestamp":1791189923385,"version":"4.1.0"},"reference-count":62,"publisher":"American Chemical Society (ACS)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Proteome Res."],"published-print":{"date-parts":[[2008,2,1]]},"DOI":"10.1021\/pr700610z","type":"journal-article","created":{"date-parts":[[2007,12,28]],"date-time":"2007-12-28T06:00:45Z","timestamp":1198821645000},"page":"708-719","source":"Crossref","is-referenced-by-count":73,"title":["Snake Venomics of Central American Pitvipers: Clues for Rationalizing the Distinct Envenomation Profiles of Atropoides nummifer and Atropoides picadoi"],"prefix":"10.1021","volume":"7","author":[{"given":"Yamileth","family":"Angulo","sequence":"first","affiliation":[{"name":"Instituto Clodomiro Picado, Facultad de Microbiolog\u00eda, Universidad de Costa Rica, San Jos\u00e9, Costa Rica, and Instituto de Biomedicina de Valencia, Consejo Superior de Investigaciones Cient\u00edficas (CSIC), Jaume Roig 11, 46010 Valencia, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9","family":"Escolano","sequence":"additional","affiliation":[{"name":"Instituto Clodomiro Picado, Facultad de Microbiolog\u00eda, Universidad de Costa Rica, San Jos\u00e9, Costa Rica, and Instituto de Biomedicina de Valencia, Consejo Superior de Investigaciones Cient\u00edficas (CSIC), Jaume Roig 11, 46010 Valencia, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruno","family":"Lomonte","sequence":"additional","affiliation":[{"name":"Instituto Clodomiro Picado, Facultad de Microbiolog\u00eda, Universidad de Costa Rica, San Jos\u00e9, Costa Rica, and Instituto de Biomedicina de Valencia, Consejo Superior de Investigaciones Cient\u00edficas (CSIC), Jaume Roig 11, 46010 Valencia, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 Mar\u00eda","family":"Guti\u00e9rrez","sequence":"additional","affiliation":[{"name":"Instituto Clodomiro Picado, Facultad de Microbiolog\u00eda, Universidad de Costa Rica, San Jos\u00e9, Costa Rica, and Instituto de Biomedicina de Valencia, Consejo Superior de Investigaciones Cient\u00edficas (CSIC), Jaume Roig 11, 46010 Valencia, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Libia","family":"Sanz","sequence":"additional","affiliation":[{"name":"Instituto Clodomiro Picado, Facultad de Microbiolog\u00eda, Universidad de Costa Rica, San Jos\u00e9, Costa Rica, and Instituto de Biomedicina de Valencia, Consejo Superior de Investigaciones Cient\u00edficas (CSIC), Jaume Roig 11, 46010 Valencia, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan J.","family":"Calvete","sequence":"additional","affiliation":[{"name":"Instituto Clodomiro Picado, Facultad de Microbiolog\u00eda, Universidad de Costa Rica, San Jos\u00e9, Costa Rica, and Instituto de Biomedicina de Valencia, Consejo Superior de Investigaciones Cient\u00edficas (CSIC), Jaume Roig 11, 46010 Valencia, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2007,12,28]]},"reference":[{"key":"ref1\/cit1","volume-title":"The Venomous Reptiles of the Western Hemisphere","author":"Campbell J. A.","year":"2004"},{"key":"ref2\/cit2","doi-asserted-by":"crossref","first-page":"881","DOI":"10.1016\/j.ympev.2005.05.013","volume":"37","author":"Castoe T. A.","year":"2005","journal-title":"Mol. Philogenet. Evol."},{"key":"ref3\/cit3","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/j.ympev.2005.12.014","volume":"39","author":"Castoe T. A.","year":"2006","journal-title":"Mol. Phylogenet. Evol."},{"key":"ref4\/cit4","first-page":"97","volume":"21","author":"P\u00e9rez-Higareda G.","year":"1985","journal-title":"Bull. Md. Herpetol. Soc."},{"key":"ref5\/cit5","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/S1095-6433(01)00312-9","volume":"129","author":"Rojas E.","year":"2001","journal-title":"Comp. Biochem. Physiol., Part C: Pharmacol., Toxicol. Endocrinol."},{"key":"ref6\/cit6","doi-asserted-by":"crossref","first-page":"841","DOI":"10.1016\/0041-0101(89)90096-2","volume":"27","author":"Gen\u00e9 J. A.","year":"1989","journal-title":"Toxicon"},{"key":"ref7\/cit7","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1016\/0041-0101(89)90040-8","volume":"27","author":"Guti\u00e9rrez J. M.","year":"1989","journal-title":"Toxicon"},{"key":"ref8\/cit8","volume-title":"The Venomous Reptiles of the Western Hemisphere","author":"Warrell D. A.","year":"2004"},{"key":"ref9\/cit9","first-page":"37","volume":"31","author":"Lomonte B.","year":"1983","journal-title":"Rev. Biol. Trop."},{"key":"ref10\/cit10","doi-asserted-by":"crossref","first-page":"887","DOI":"10.1016\/0041-0101(85)90380-0","volume":"23","author":"Guti\u00e9rrez J. M.","year":"1985","journal-title":"Toxicon"},{"key":"ref11\/cit11","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1081\/TXR-120004740","volume":"21","author":"Vidal N.","year":"2002","journal-title":"J. Toxicol. Toxin Rev."},{"key":"ref12\/cit12","doi-asserted-by":"crossref","first-page":"870","DOI":"10.1093\/molbev\/msh091","volume":"21","author":"Fry B. G.","year":"2004","journal-title":"Mol. Biol. Evol."},{"key":"ref13\/cit13","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1101\/gr.3228405","volume":"15","author":"Fry B. G.","year":"2005","journal-title":"Genome Res."},{"key":"ref14\/cit14","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1038\/nature04328","volume":"439","author":"Fry B. G.","year":"2006","journal-title":"Nature"},{"key":"ref15\/cit15","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1093\/icb\/23.2.431","volume":"23","author":"Greene H. W.","year":"1983","journal-title":"Am. Zool."},{"key":"ref16\/cit16","doi-asserted-by":"crossref","first-page":"2732","DOI":"10.1021\/pr0701714","volume":"6","author":"Calvete J. J.","year":"2007","journal-title":"J. Proteome Res."},{"key":"ref17\/cit17","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1016\/j.toxicon.2005.12.010","volume":"47","author":"M\u00e9nez A.","year":"2006","journal-title":"Toxicon"},{"key":"ref18\/cit18","doi-asserted-by":"crossref","first-page":"1268","DOI":"10.1016\/S1357-2725(02)00060-2","volume":"34","author":"Angulo Y.","year":"2002","journal-title":"Int. J. Biochem. Cell Biol."},{"key":"ref19\/cit19","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1002\/pmic.200300628","volume":"4","author":"Ju\u00e1rez P.","year":"2004","journal-title":"Proteomics"},{"key":"ref20\/cit20","doi-asserted-by":"crossref","first-page":"2098","DOI":"10.1021\/pr0602500","volume":"5","author":"Sanz L.","year":"2006","journal-title":"J. Proteome Res."},{"key":"ref21\/cit21","doi-asserted-by":"crossref","first-page":"4223","DOI":"10.1002\/pmic.200402024","volume":"5","author":"Bazaa A.","year":"2005","journal-title":"Proteomics"},{"key":"ref22\/cit22","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1007\/s00239-005-0268-z","volume":"63","author":"Ju\u00e1rez P.","year":"2006","journal-title":"J. Mol. Evol."},{"key":"ref23\/cit23","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1021\/pr060494k","volume":"6","author":"Calvete J. J.","year":"2007","journal-title":"J. Proteome Res."},{"key":"ref24\/cit24","doi-asserted-by":"crossref","first-page":"3389","DOI":"10.1093\/nar\/25.17.3389","volume":"25","author":"Altschul S. F.","year":"1997","journal-title":"Nucleic Acids Res."},{"key":"ref25\/cit25","doi-asserted-by":"crossref","first-page":"859","DOI":"10.1002\/pmic.200300415","volume":"3","author":"Le Blanc J. C.","year":"2003","journal-title":"Proteomics"},{"key":"ref26\/cit26","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1038\/327147a0","volume":"327","author":"Wetton J. H.","year":"1987","journal-title":"Nature"},{"key":"ref27\/cit27","volume-title":"Perspectives in Molecular Toxinology","author":"M\u00e9nez A.","year":"2002"},{"key":"ref28\/cit28","doi-asserted-by":"crossref","first-page":"867","DOI":"10.1007\/BF00173166","volume":"41","author":"Ogawa T.","year":"1995","journal-title":"J. Mol. Evol."},{"key":"ref29\/cit29","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.toxicon.2004.07.028","volume":"45","author":"Ogawa T.","year":"2005","journal-title":"Toxicon"},{"key":"ref30\/cit30","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1111\/j.1432-1033.1996.0083h.x","volume":"240","author":"Kordis D.","year":"1996","journal-title":"Eur. J. Biochem."},{"key":"ref31\/cit31","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/S0014-5793(96)01144-1","volume":"397","author":"Deshimaru M.","year":"1996","journal-title":"FEBS Lett."},{"key":"ref32\/cit32","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1016\/S0079-6603(08)61036-3","volume":"59","author":"Ohno M.","year":"1998","journal-title":"Prog. Nucleic Acid Res. Mol. Biol."},{"key":"ref33\/cit33","doi-asserted-by":"crossref","first-page":"1953","DOI":"10.1046\/j.1365-294X.2000.01125.x","volume":"9","author":"Richman A.","year":"2000","journal-title":"Mol. Ecol."},{"key":"ref34\/cit34","doi-asserted-by":"crossref","first-page":"5964","DOI":"10.1073\/pnas.90.13.5964","volume":"90","author":"Nakashima K.","year":"1993","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"ref35\/cit35","doi-asserted-by":"crossref","first-page":"5605","DOI":"10.1073\/pnas.92.12.5605","volume":"92","author":"Nakashima K.","year":"1995","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"ref36\/cit36","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1042\/bj3470491","volume":"347","author":"Chijiwa T.","year":"2000","journal-title":"Biochem. J."},{"key":"ref37\/cit37","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1007\/s00239-002-2400-7","volume":"56","author":"Chijiwa T.","year":"2003","journal-title":"J. Mol. Evol."},{"key":"ref38\/cit38","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/j.bbapap.2004.08.006","volume":"1702","author":"Tsai I.-H.","year":"2004","journal-title":"Biochim. Biophys. Acta"},{"key":"ref39\/cit39","doi-asserted-by":"crossref","first-page":"841","DOI":"10.1016\/j.toxicon.2003.11.003","volume":"42","author":"Ohno M.","year":"2003","journal-title":"Toxicon"},{"key":"ref40\/cit40","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1007\/s00239-002-2403-4","volume":"56","author":"Creer S.","year":"2003","journal-title":"J. Mol. Evol."},{"key":"ref41\/cit41","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1007\/s00239-003-2497-3","volume":"57","author":"Fry B. G.","year":"2003","journal-title":"J. Mol. Evol."},{"key":"ref42\/cit42","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1254\/jphs.94.1","volume":"94","author":"Nirthanan S.","year":"2004","journal-title":"J. Pharmacol. Sci."},{"key":"ref43\/cit43","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1034\/j.1399-3011.2002.02969.x","volume":"59","author":"Shelke R. R.","year":"2002","journal-title":"J. Pept. Res."},{"key":"ref44\/cit44","doi-asserted-by":"crossref","first-page":"877","DOI":"10.1534\/genetics.106.056515","volume":"173","author":"Junqueira-de-Azevedo I. L. M.","year":"2006","journal-title":"Genetics"},{"key":"ref45\/cit45","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1007\/s00239-003-2497-3","volume":"57","author":"Fry B. G.","year":"2003","journal-title":"J. Mol. Evol."},{"key":"ref46\/cit46","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1016\/j.toxicon.2004.11.003","volume":"45","author":"Lumden N. G.","year":"2005","journal-title":"Toxicon"},{"key":"ref47\/cit47","doi-asserted-by":"crossref","first-page":"29030","DOI":"10.1074\/jbc.M605850200","author":"Pawlak J.","year":"2006","journal-title":"J. Biol. Chem."},{"key":"ref48\/cit48","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1655\/01-105.2","volume":"59","author":"Castoe T. A.","year":"2003","journal-title":"Herpetologica"},{"key":"ref49\/cit49","doi-asserted-by":"crossref","first-page":"915","DOI":"10.1016\/j.toxicon.2003.11.005","volume":"42","author":"Gutierrez J. M.","year":"2003","journal-title":"Toxicon"},{"key":"ref50\/cit50","doi-asserted-by":"crossref","first-page":"885","DOI":"10.1016\/j.toxicon.2003.11.008","volume":"42","author":"Lomonte B.","year":"2003","journal-title":"Toxicon"},{"key":"ref51\/cit51","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1107\/S1744309106010700","volume":"62","author":"Murakami M. Y.","year":"2006","journal-title":"Acta Crystallogr., Sect. F: Struct. Biol. Cryst. Commun."},{"key":"ref52\/cit52","doi-asserted-by":"crossref","first-page":"869","DOI":"10.1016\/j.toxicon.2003.11.027","volume":"42","author":"Chioato R.","year":"2003","journal-title":"Toxicon"},{"key":"ref53\/cit53","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1006\/abbi.2001.2524","volume":"394","author":"Tsai I.-H.","year":"2001","journal-title":"Arch. Biochem. Biophys."},{"key":"ref54\/cit54","doi-asserted-by":"crossref","first-page":"29867","DOI":"10.1016\/S0021-9258(18)43961-0","volume":"269","author":"Lomonte B.","year":"1994","journal-title":"J. Biol. Chem."},{"key":"ref55\/cit55","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1016\/S0041-0101(98)00211-6","volume":"37","author":"Calder\u00f3n L.","year":"1999","journal-title":"Toxicon"},{"key":"ref56\/cit56","doi-asserted-by":"crossref","first-page":"997","DOI":"10.1016\/j.toxicon.2005.02.029","volume":"45","author":"Guti\u00e9rrez J. M.","year":"2005","journal-title":"Toxicon"},{"key":"ref57\/cit57","doi-asserted-by":"crossref","first-page":"969","DOI":"10.1016\/j.toxicon.2005.02.012","volume":"45","author":"Fox J. W.","year":"2005","journal-title":"Toxicon"},{"key":"ref58\/cit58","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/0041-0101(92)90869-7","volume":"30","author":"Kini R. M.","year":"1992","journal-title":"Toxicon"},{"key":"ref59\/cit59","doi-asserted-by":"crossref","first-page":"1269","DOI":"10.1016\/S0041-0101(96)00108-0","volume":"34","author":"Jia L.-G.","year":"1996","journal-title":"Toxicon"},{"key":"ref60\/cit60","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1016\/0163-7258(94)90049-3","volume":"62","author":"Bjarnason J. B.","year":"1994","journal-title":"Pharmacol. Ther."},{"key":"ref61\/cit61","first-page":"3","volume":"34","author":"Taylor E. H.","year":"1951","journal-title":"Kans. Univ. Sci. Bull."},{"key":"ref62\/cit62","first-page":"7","volume-title":"Toxins","volume":"30","author":"Jim\u00e9nez-Porras J. M.","year":"1967"}],"container-title":["Journal of Proteome Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/pr700610z","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,3,24]],"date-time":"2023-03-24T10:24:59Z","timestamp":1679653499000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/pr700610z"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,12,28]]},"references-count":62,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2008,2,1]]}},"alternative-id":["10.1021\/pr700610z"],"URL":"https:\/\/doi.org\/10.1021\/pr700610z","relation":{},"ISSN":["1535-3893","1535-3907"],"issn-type":[{"value":"1535-3893","type":"print"},{"value":"1535-3907","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,12,28]]}}}