{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T00:32:27Z","timestamp":1790209947166,"version":"4.1.0"},"reference-count":61,"publisher":"American Chemical Society (ACS)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Proteome Res."],"published-print":{"date-parts":[[2010,5,7]]},"DOI":"10.1021\/pr900941z","type":"journal-article","created":{"date-parts":[[2010,3,5]],"date-time":"2010-03-05T13:22:02Z","timestamp":1267795322000},"page":"2191-2199","source":"Crossref","is-referenced-by-count":133,"title":["Application of Label-Free Absolute Quantitative Proteomics in Human Gingival Crevicular Fluid by LC\/MS<sup>E<\/sup> (Gingival Exudatome)"],"prefix":"10.1021","volume":"9","author":[{"given":"N.","family":"Bostanci","sequence":"first","affiliation":[{"name":"Periodontology Unit, Division of Clinical Research, UCL Eastman Dental Institute, London, U.K., Institute of Oral Biology, Center for Dental and Oral Medicine and Cranio-Maxillofacial Surgery, Faculty of Medicine, University of Z\u00fcrich, Z\u00fcrich, Switzerland, Division of Biomaterials and Tissue Engineering, UCL Eastman Dental Institute, London, U.K., and Biochemistry Group, Clinical and Molecular Genetics Unit, UCL Institute of Child Health, London, U.K."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"W.","family":"Heywood","sequence":"additional","affiliation":[{"name":"Periodontology Unit, Division of Clinical Research, UCL Eastman Dental Institute, London, U.K., Institute of Oral Biology, Center for Dental and Oral Medicine and Cranio-Maxillofacial Surgery, Faculty of Medicine, University of Z\u00fcrich, Z\u00fcrich, Switzerland, Division of Biomaterials and Tissue Engineering, UCL Eastman Dental Institute, London, U.K., and Biochemistry Group, Clinical and Molecular Genetics Unit, UCL Institute of Child Health, London, U.K."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.","family":"Mills","sequence":"additional","affiliation":[{"name":"Periodontology Unit, Division of Clinical Research, UCL Eastman Dental Institute, London, U.K., Institute of Oral Biology, Center for Dental and Oral Medicine and Cranio-Maxillofacial Surgery, Faculty of Medicine, University of Z\u00fcrich, Z\u00fcrich, Switzerland, Division of Biomaterials and Tissue Engineering, UCL Eastman Dental Institute, London, U.K., and Biochemistry Group, Clinical and Molecular Genetics Unit, UCL Institute of Child Health, London, U.K."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Parkar","sequence":"additional","affiliation":[{"name":"Periodontology Unit, Division of Clinical Research, UCL Eastman Dental Institute, London, U.K., Institute of Oral Biology, Center for Dental and Oral Medicine and Cranio-Maxillofacial Surgery, Faculty of Medicine, University of Z\u00fcrich, Z\u00fcrich, Switzerland, Division of Biomaterials and Tissue Engineering, UCL Eastman Dental Institute, London, U.K., and Biochemistry Group, Clinical and Molecular Genetics Unit, UCL Institute of Child Health, London, U.K."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"Nibali","sequence":"additional","affiliation":[{"name":"Periodontology Unit, Division of Clinical Research, UCL Eastman Dental Institute, London, U.K., Institute of Oral Biology, Center for Dental and Oral Medicine and Cranio-Maxillofacial Surgery, Faculty of Medicine, University of Z\u00fcrich, Z\u00fcrich, Switzerland, Division of Biomaterials and Tissue Engineering, UCL Eastman Dental Institute, London, U.K., and Biochemistry Group, Clinical and Molecular Genetics Unit, UCL Institute of Child Health, London, U.K."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N.","family":"Donos","sequence":"additional","affiliation":[{"name":"Periodontology Unit, Division of Clinical Research, UCL Eastman Dental Institute, London, U.K., Institute of Oral Biology, Center for Dental and Oral Medicine and Cranio-Maxillofacial Surgery, Faculty of Medicine, University of Z\u00fcrich, Z\u00fcrich, Switzerland, Division of Biomaterials and Tissue Engineering, UCL Eastman Dental Institute, London, U.K., and Biochemistry Group, Clinical and Molecular Genetics Unit, UCL Institute of Child Health, London, U.K."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2010,3,26]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1111\/j.1600-0757.1993.tb00220.x","volume":"2","author":"Brown L. J.","year":"1993","journal-title":"Periodontol 2000"},{"key":"ref2\/cit2","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1034\/j.1600-0757.2002.290110.x","volume":"29","author":"Albandar J. M.","year":"2002","journal-title":"Periodontol 2000"},{"issue":"9075","key":"ref3\/cit3","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1016\/S0140-6736(97)03079-1","volume":"350","author":"Danesh J.","year":"1997","journal-title":"Lancet"},{"issue":"1","key":"ref4\/cit4","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/0022-5193(74)90103-9","volume":"47","author":"Alfano M. C.","year":"1974","journal-title":"J. Theor. Biol."},{"issue":"9","key":"ref5\/cit5","doi-asserted-by":"crossref","first-page":"1627","DOI":"10.1177\/00220345960750090201","volume":"75","author":"Krasse B.","year":"1996","journal-title":"J. Dent. Res."},{"key":"ref6\/cit6","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1034\/j.1600-0757.2003.03109.x","volume":"31","author":"Ebersole J. L.","year":"2003","journal-title":"Periodontol 2000"},{"issue":"6","key":"ref7\/cit7","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1111\/j.1600-051X.1988.tb01010.x","volume":"15","author":"Lamster I. B.","year":"1988","journal-title":"J. Clin. Periodontol."},{"key":"ref8\/cit8","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1034\/j.1600-0757.2003.03110.x","volume":"31","author":"Champagne C. M.","year":"2003","journal-title":"Periodontol 2000"},{"issue":"5","key":"ref9\/cit9","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1111\/j.1600-051X.2007.01061.x","volume":"34","author":"Bostanci N.","year":"2007","journal-title":"J. Clin. Periodontol."},{"issue":"8","key":"ref10\/cit10","first-page":"49","author":"Golub L. M.","year":"1976","journal-title":"Oral Sci. Rev."},{"issue":"6","key":"ref11\/cit11","doi-asserted-by":"crossref","first-page":"462","DOI":"10.1111\/j.1600-0722.2005.00246.x","volume":"113","author":"Pisano E.","year":"2005","journal-title":"Eur. J. Oral Sci."},{"issue":"8","key":"ref12\/cit12","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1016\/S0003-9969(96)00076-3","volume":"41","author":"Estreicher A.","year":"1996","journal-title":"Arch. Oral Biol."},{"key":"ref13\/cit13","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1196\/annals.1384.027","volume":"1098","author":"Lamster I. B.","year":"2007","journal-title":"Ann. N.Y. Acad. Sci."},{"issue":"1","key":"ref14\/cit14","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.cccn.2004.01.022","volume":"343","author":"Ozmeric N.","year":"2004","journal-title":"Clin. Chim. Acta"},{"key":"ref15\/cit15","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1034\/j.1600-0757.2003.03101.x","volume":"31","author":"Uitto V. J.","year":"2003","journal-title":"Periodontol 2000"},{"issue":"1","key":"ref16\/cit16","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1021\/pr8003776","volume":"8","author":"Rao P. V.","year":"2009","journal-title":"J. Proteome Res."},{"issue":"4","key":"ref17\/cit17","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1074\/mcp.M500321-MCP200","volume":"5","author":"Silva J. C.","year":"2006","journal-title":"Mol. Cell. Proteomics"},{"issue":"7","key":"ref18\/cit18","doi-asserted-by":"crossref","first-page":"2187","DOI":"10.1021\/ac048455k","volume":"77","author":"Silva J. C.","year":"2005","journal-title":"Anal. Chem."},{"issue":"1","key":"ref19\/cit19","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1902\/annals.1999.4.1.1","volume":"4","author":"Armitage G. C.","year":"1999","journal-title":"Ann. Periodontol."},{"issue":"2","key":"ref20\/cit20","first-page":"107","volume":"15","author":"Muhlemann H. R.","year":"1971","journal-title":"Helv. Odontol. Acta"},{"key":"ref21\/cit21","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1046\/j.0906-6713.2002.003421.x","volume":"34","author":"Armitage G. C.","year":"2004","journal-title":"Periodontol 2000"},{"issue":"1","key":"ref22\/cit22","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1902\/annals.1997.2.1.123","volume":"2","author":"Lamster I. B.","year":"1997","journal-title":"Ann. Periodontol."},{"issue":"4","key":"ref23\/cit23","doi-asserted-by":"crossref","first-page":"1073","DOI":"10.1021\/pr0500657","volume":"4","author":"Jacobs J. M.","year":"2005","journal-title":"J. Proteome Res."},{"issue":"3","key":"ref24\/cit24","doi-asserted-by":"crossref","first-page":"762","DOI":"10.2337\/diabetes.51.3.762","volume":"51","author":"Dea M. K.","year":"2002","journal-title":"Diabetes"},{"issue":"2","key":"ref25\/cit25","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1111\/j.1600-051X.1996.tb00537.x","volume":"23","author":"Tervahartiala T.","year":"1996","journal-title":"J. Clin. Periodontol."},{"key":"ref26\/cit26","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1111\/j.1749-6632.1999.tb07679.x","volume":"878","author":"Sorsa T.","year":"1999","journal-title":"Ann. N.Y. Acad. Sci."},{"issue":"3","key":"ref27\/cit27","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1902\/jop.2000.71.3.460","volume":"71","author":"Yamalik N.","year":"2000","journal-title":"J. Periodontol."},{"issue":"1","key":"ref28\/cit28","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1016\/j.chroma.2007.10.059","volume":"1189","author":"Freije R.","year":"2008","journal-title":"J. Chromatogr. A"},{"issue":"2","key":"ref29\/cit29","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/S0163-7258(98)00028-X","volume":"80","author":"Kiang J. G.","year":"1998","journal-title":"Pharmacol. Ther."},{"issue":"6","key":"ref30\/cit30","doi-asserted-by":"crossref","first-page":"2211","DOI":"10.1021\/pr070031u","volume":"6","author":"Saba J. A.","year":"2007","journal-title":"J. Proteome Res."},{"issue":"16","key":"ref31\/cit31","doi-asserted-by":"crossref","first-page":"9331","DOI":"10.1073\/pnas.95.16.9331","volume":"95","author":"Jones S. L.","year":"1998","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"issue":"8","key":"ref32\/cit32","doi-asserted-by":"crossref","first-page":"718","DOI":"10.1177\/154405910708600806","volume":"86","author":"Matthews J. B.","year":"2007","journal-title":"J. Dent. Res."},{"issue":"5","key":"ref33\/cit33","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1016\/j.molimm.2004.09.008","volume":"42","author":"Lundy F. T.","year":"2005","journal-title":"Mol. Immunol."},{"issue":"2","key":"ref34\/cit34","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1034\/j.1399-302X.2003.00047.x","volume":"18","author":"Brogden K. A.","year":"2003","journal-title":"Oral Microbiol. Immunol."},{"issue":"1","key":"ref35\/cit35","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1111\/j.1600-051X.1998.tb02361.x","volume":"25","author":"Chen H. Y.","year":"1998","journal-title":"J. Clin. Periodontol."},{"issue":"3","key":"ref36\/cit36","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1177\/154411130201300304","volume":"13","author":"Dickinson D. P.","year":"2002","journal-title":"Crit. Rev. Oral Biol. Med."},{"issue":"7","key":"ref37\/cit37","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1111\/j.1600-0765.1997.tb00935.x","volume":"32","author":"Blankenvoorde M. F.","year":"1997","journal-title":"J. Periodontal Res."},{"issue":"1","key":"ref38\/cit38","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1016\/S0065-1281(87)80043-0","volume":"82","author":"Jarvinen M.","year":"1987","journal-title":"Acta Histochem."},{"issue":"4","key":"ref39\/cit39","doi-asserted-by":"crossref","first-page":"1111","DOI":"10.1016\/j.bbrc.2004.07.096","volume":"322","author":"Marenholz I.","year":"2004","journal-title":"Biochem. Biophys. Res. Commun."},{"issue":"1","key":"ref40\/cit40","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1038\/nri2470","volume":"9","author":"Perretti M.","year":"2009","journal-title":"Nat. Rev. Immunol."},{"issue":"4","key":"ref41\/cit41","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1007\/s00011-003-1235-z","volume":"53","author":"Parente L.","year":"2004","journal-title":"Inflammation Res."},{"issue":"7","key":"ref42\/cit42","doi-asserted-by":"crossref","first-page":"1538","DOI":"10.1002\/1529-0131(199907)42:7<1538::AID-ANR29>3.0.CO;2-3","volume":"42","author":"Yang Y.","year":"1999","journal-title":"Arthritis Rheum."},{"issue":"6","key":"ref43\/cit43","doi-asserted-by":"crossref","first-page":"1607","DOI":"10.1016\/S0002-9440(10)62471-6","volume":"166","author":"Damazo A. S.","year":"2005","journal-title":"Am. J. Pathol."},{"issue":"5","key":"ref44\/cit44","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1111\/j.1600-0765.2006.00891.x","volume":"41","author":"Cox S. W.","year":"2006","journal-title":"J. Periodontal Res."},{"issue":"5","key":"ref45\/cit45","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1016\/S0025-6196(11)64212-2","volume":"75","author":"Yang P.","year":"2000","journal-title":"Mayo Clin Proc"},{"issue":"1","key":"ref46\/cit46","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1902\/jop.1979.50.1.31","volume":"50","author":"Peterson R. J.","year":"1979","journal-title":"J. Periodontol."},{"issue":"1","key":"ref47\/cit47","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/S0167-4838(00)00153-9","volume":"1482","author":"Fournier T.","year":"2000","journal-title":"Biochim. Biophys. Acta"},{"issue":"1","key":"ref48\/cit48","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/S1359-6101(02)00054-0","volume":"14","author":"Hochepied T.","year":"2003","journal-title":"Cytokine Growth Factor Rev."},{"issue":"2","key":"ref49\/cit49","first-page":"425","volume":"9","author":"Glurich I.","year":"2002","journal-title":"Clin. Diagn. Lab. Immunol."},{"issue":"1","key":"ref50\/cit50","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/0003-9969(93)90155-F","volume":"38","author":"Wilton J. M.","year":"1993","journal-title":"Arch. Oral Biol."},{"key":"ref51\/cit51","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1034\/j.1600-0757.2003.03107.x","volume":"31","author":"Eley B. M.","year":"2003","journal-title":"Periodontol 2000"},{"issue":"2","key":"ref52\/cit52","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1111\/j.1399-302X.1997.tb00626.x","volume":"12","author":"Mooney J.","year":"1997","journal-title":"Oral Microbiol. Immunol."},{"issue":"1","key":"ref53\/cit53","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1902\/jop.1989.60.1.44","volume":"60","author":"Reinhardt R. A.","year":"1989","journal-title":"J. Periodontol."},{"issue":"2","key":"ref54\/cit54","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1111\/j.1432-0436.1985.tb00523.x","volume":"30","author":"Ouhayoun J. P.","year":"1985","journal-title":"Differentiation"},{"issue":"6","key":"ref55\/cit55","doi-asserted-by":"crossref","first-page":"468","DOI":"10.1111\/j.1600-0765.1991.tb01797.x","volume":"26","author":"Mackenzie I. C.","year":"1991","journal-title":"J. Periodontal Res."},{"issue":"1","key":"ref56\/cit56","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1111\/j.1600-0765.1993.tb01050.x","volume":"28","author":"Mackenzie I. C.","year":"1993","journal-title":"J. Periodontal Res."},{"issue":"11","key":"ref57\/cit57","doi-asserted-by":"crossref","first-page":"1326","DOI":"10.1177\/00220345860650110901","volume":"65","author":"Rowat J. S.","year":"1986","journal-title":"J. Dent. Res."},{"issue":"5","key":"ref58\/cit58","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1111\/j.1600-0765.1990.tb00917.x","volume":"25","author":"Ouhayoun J. P.","year":"1990","journal-title":"J. Periodontal Res."},{"issue":"3","key":"ref59\/cit59","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1097\/QCO.0b013e3280964da0","volume":"20","author":"Slots J.","year":"2007","journal-title":"Curr. Opin. Infect. Dis."},{"issue":"3","key":"ref60\/cit60","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1177\/10454411010120030101","volume":"12","author":"Curtis M. A.","year":"2001","journal-title":"Crit. Rev. Oral Biol. Med."},{"issue":"3","key":"ref61\/cit61","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1111\/j.1600-051X.2006.01034.x","volume":"34","author":"Aas J. A.","year":"2007","journal-title":"J. Clin. Periodontol."}],"container-title":["Journal of Proteome Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/pr900941z","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,3,7]],"date-time":"2023-03-07T02:39:31Z","timestamp":1678156771000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/pr900941z"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,3,26]]},"references-count":61,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2010,5,7]]}},"alternative-id":["10.1021\/pr900941z"],"URL":"https:\/\/doi.org\/10.1021\/pr900941z","relation":{},"ISSN":["1535-3893","1535-3907"],"issn-type":[{"value":"1535-3893","type":"print"},{"value":"1535-3907","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,3,26]]}}}