{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T07:39:25Z","timestamp":1792136365854,"version":"4.4.0"},"reference-count":70,"publisher":"American Chemical Society (ACS)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Proteome Res."],"published-print":{"date-parts":[[2010,1,4]]},"DOI":"10.1021\/pr9009518","type":"journal-article","created":{"date-parts":[[2009,11,13]],"date-time":"2009-11-13T23:48:53Z","timestamp":1258156133000},"page":"564-577","source":"Crossref","is-referenced-by-count":74,"title":["Impact of Regional Variation in <i>Bothrops asper<\/i> Snake Venom on the Design of Antivenoms: Integrating Antivenomics and Neutralization Approaches"],"prefix":"10.1021","volume":"9","author":[{"given":"Jos\u00e9 Mar\u00eda","family":"Guti\u00e9rrez","sequence":"first","affiliation":[{"name":"Instituto Clodomiro Picado, Facultad de Microbiolog\u00eda, Universidad de Costa Rica, San Jos\u00e9, Costa Rica, Instituto de Biomedicina de Valencia, C.S.I.C., Jaume Roig 11, 46010 Valencia, Spain, Departamento de Bioqu\u00edmica, Escuela de Medicina, Universidad de Costa Rica, San Jos\u00e9, Costa Rica, Centro de Investigaci\u00f3n en Estructuras Microsc\u00f3picas (CIEMIC), Universidad de Costa Rica, San Jos\u00e9, Costa Rica, and Instituto de Medicina Experimental, Facultad de Medicina, Universidad Central de Venezuela, Caracas,..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Libia","family":"Sanz","sequence":"additional","affiliation":[{"name":"Instituto Clodomiro Picado, Facultad de Microbiolog\u00eda, Universidad de Costa Rica, San Jos\u00e9, Costa Rica, Instituto de Biomedicina de Valencia, C.S.I.C., Jaume Roig 11, 46010 Valencia, Spain, Departamento de Bioqu\u00edmica, Escuela de Medicina, Universidad de Costa Rica, San Jos\u00e9, Costa Rica, Centro de Investigaci\u00f3n en Estructuras Microsc\u00f3picas (CIEMIC), Universidad de Costa Rica, San Jos\u00e9, Costa Rica, and Instituto de Medicina Experimental, Facultad de Medicina, Universidad Central de Venezuela, Caracas,..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marietta","family":"Flores-D\u00edaz","sequence":"additional","affiliation":[{"name":"Instituto Clodomiro Picado, Facultad de Microbiolog\u00eda, Universidad de Costa Rica, San Jos\u00e9, Costa Rica, Instituto de Biomedicina de Valencia, C.S.I.C., Jaume Roig 11, 46010 Valencia, Spain, Departamento de Bioqu\u00edmica, Escuela de Medicina, Universidad de Costa Rica, San Jos\u00e9, Costa Rica, Centro de Investigaci\u00f3n en Estructuras Microsc\u00f3picas (CIEMIC), Universidad de Costa Rica, San Jos\u00e9, Costa Rica, and Instituto de Medicina Experimental, Facultad de Medicina, Universidad Central de Venezuela, Caracas,..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luc\u00eda","family":"Figueroa","sequence":"additional","affiliation":[{"name":"Instituto Clodomiro Picado, Facultad de Microbiolog\u00eda, Universidad de Costa Rica, San Jos\u00e9, Costa Rica, Instituto de Biomedicina de Valencia, C.S.I.C., Jaume Roig 11, 46010 Valencia, Spain, Departamento de Bioqu\u00edmica, Escuela de Medicina, Universidad de Costa Rica, San Jos\u00e9, Costa Rica, Centro de Investigaci\u00f3n en Estructuras Microsc\u00f3picas (CIEMIC), Universidad de Costa Rica, San Jos\u00e9, Costa Rica, and Instituto de Medicina Experimental, Facultad de Medicina, Universidad Central de Venezuela, Caracas,..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marvin","family":"Madrigal","sequence":"additional","affiliation":[{"name":"Instituto Clodomiro Picado, Facultad de Microbiolog\u00eda, Universidad de Costa Rica, San Jos\u00e9, Costa Rica, Instituto de Biomedicina de Valencia, C.S.I.C., Jaume Roig 11, 46010 Valencia, Spain, Departamento de Bioqu\u00edmica, Escuela de Medicina, Universidad de Costa Rica, San Jos\u00e9, Costa Rica, Centro de Investigaci\u00f3n en Estructuras Microsc\u00f3picas (CIEMIC), Universidad de Costa Rica, San Jos\u00e9, Costa Rica, and Instituto de Medicina Experimental, Facultad de Medicina, Universidad Central de Venezuela, Caracas,..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00eda","family":"Herrera","sequence":"additional","affiliation":[{"name":"Instituto Clodomiro Picado, Facultad de Microbiolog\u00eda, Universidad de Costa Rica, San Jos\u00e9, Costa Rica, Instituto de Biomedicina de Valencia, C.S.I.C., Jaume Roig 11, 46010 Valencia, Spain, Departamento de Bioqu\u00edmica, Escuela de Medicina, Universidad de Costa Rica, San Jos\u00e9, Costa Rica, Centro de Investigaci\u00f3n en Estructuras Microsc\u00f3picas (CIEMIC), Universidad de Costa Rica, San Jos\u00e9, Costa Rica, and Instituto de Medicina Experimental, Facultad de Medicina, Universidad Central de Venezuela, Caracas,..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mauren","family":"Villalta","sequence":"additional","affiliation":[{"name":"Instituto Clodomiro Picado, Facultad de Microbiolog\u00eda, Universidad de Costa Rica, San Jos\u00e9, Costa Rica, Instituto de Biomedicina de Valencia, C.S.I.C., Jaume Roig 11, 46010 Valencia, Spain, Departamento de Bioqu\u00edmica, Escuela de Medicina, Universidad de Costa Rica, San Jos\u00e9, Costa Rica, Centro de Investigaci\u00f3n en Estructuras Microsc\u00f3picas (CIEMIC), Universidad de Costa Rica, San Jos\u00e9, Costa Rica, and Instituto de Medicina Experimental, Facultad de Medicina, Universidad Central de Venezuela, Caracas,..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guillermo","family":"Le\u00f3n","sequence":"additional","affiliation":[{"name":"Instituto Clodomiro Picado, Facultad de Microbiolog\u00eda, Universidad de Costa Rica, San Jos\u00e9, Costa Rica, Instituto de Biomedicina de Valencia, C.S.I.C., Jaume Roig 11, 46010 Valencia, Spain, Departamento de Bioqu\u00edmica, Escuela de Medicina, Universidad de Costa Rica, San Jos\u00e9, Costa Rica, Centro de Investigaci\u00f3n en Estructuras Microsc\u00f3picas (CIEMIC), Universidad de Costa Rica, San Jos\u00e9, Costa Rica, and Instituto de Medicina Experimental, Facultad de Medicina, Universidad Central de Venezuela, Caracas,..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ricardo","family":"Estrada","sequence":"additional","affiliation":[{"name":"Instituto Clodomiro Picado, Facultad de Microbiolog\u00eda, Universidad de Costa Rica, San Jos\u00e9, Costa Rica, Instituto de Biomedicina de Valencia, C.S.I.C., Jaume Roig 11, 46010 Valencia, Spain, Departamento de Bioqu\u00edmica, Escuela de Medicina, Universidad de Costa Rica, San Jos\u00e9, Costa Rica, Centro de Investigaci\u00f3n en Estructuras Microsc\u00f3picas (CIEMIC), Universidad de Costa Rica, San Jos\u00e9, Costa Rica, and Instituto de Medicina Experimental, Facultad de Medicina, Universidad Central de Venezuela, Caracas,..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adolfo","family":"Borges","sequence":"additional","affiliation":[{"name":"Instituto Clodomiro Picado, Facultad de Microbiolog\u00eda, Universidad de Costa Rica, San Jos\u00e9, Costa Rica, Instituto de Biomedicina de Valencia, C.S.I.C., Jaume Roig 11, 46010 Valencia, Spain, Departamento de Bioqu\u00edmica, Escuela de Medicina, Universidad de Costa Rica, San Jos\u00e9, Costa Rica, Centro de Investigaci\u00f3n en Estructuras Microsc\u00f3picas (CIEMIC), Universidad de Costa Rica, San Jos\u00e9, Costa Rica, and Instituto de Medicina Experimental, Facultad de Medicina, Universidad Central de Venezuela, Caracas,..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alberto","family":"Alape-Gir\u00f3n","sequence":"additional","affiliation":[{"name":"Instituto Clodomiro Picado, Facultad de Microbiolog\u00eda, Universidad de Costa Rica, San Jos\u00e9, Costa Rica, Instituto de Biomedicina de Valencia, C.S.I.C., Jaume Roig 11, 46010 Valencia, Spain, Departamento de Bioqu\u00edmica, Escuela de Medicina, Universidad de Costa Rica, San Jos\u00e9, Costa Rica, Centro de Investigaci\u00f3n en Estructuras Microsc\u00f3picas (CIEMIC), Universidad de Costa Rica, San Jos\u00e9, Costa Rica, and Instituto de Medicina Experimental, Facultad de Medicina, Universidad Central de Venezuela, Caracas,..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan J.","family":"Calvete","sequence":"additional","affiliation":[{"name":"Instituto Clodomiro Picado, Facultad de Microbiolog\u00eda, Universidad de Costa Rica, San Jos\u00e9, Costa Rica, Instituto de Biomedicina de Valencia, C.S.I.C., Jaume Roig 11, 46010 Valencia, Spain, Departamento de Bioqu\u00edmica, Escuela de Medicina, Universidad de Costa Rica, San Jos\u00e9, Costa Rica, Centro de Investigaci\u00f3n en Estructuras Microsc\u00f3picas (CIEMIC), Universidad de Costa Rica, San Jos\u00e9, Costa Rica, and Instituto de Medicina Experimental, Facultad de Medicina, Universidad Central de Venezuela, Caracas,..."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2009,11,24]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"crossref","first-page":"e150\u2212159","DOI":"10.1371\/journal.pmed.0030150","volume":"3","author":"Guti\u00e9rrez J. M.","year":"2006","journal-title":"PLoS Med."},{"key":"ref2\/cit2","volume-title":"Rabies and Envenomings. A neglected Public Health Issue. Report of a Consultative Meeting","year":"2007"},{"key":"ref3\/cit3","first-page":"515","volume":"76","author":"Chippaux J. P.","year":"1998","journal-title":"Bull. World Health Org."},{"key":"ref4\/cit4","doi-asserted-by":"crossref","first-page":"e218","DOI":"10.1371\/journal.pmed.0050218","volume":"5","author":"Kasturiratne A.","year":"2008","journal-title":"PLoS Med."},{"key":"ref5\/cit5","volume-title":"Handbook of Clinical Toxicology of Animal Venoms and Poisons","author":"Guti\u00e9rrez J. M.","year":"1995"},{"key":"ref6\/cit6","volume-title":"Handbook of Clinical Toxicology of Animal Venoms and Poisons","author":"Fan H. W.","year":"1995"},{"key":"ref7\/cit7","volume-title":"The Venomous Reptiles of the Western Hemisphere","author":"Campbell J. A.","year":"2004"},{"key":"ref8\/cit8","first-page":"165","volume":"3","author":"Bola\u00f1os R.","year":"1982","journal-title":"Rev. Costarricense Cienc. M\u00e9d."},{"key":"ref9\/cit9","volume-title":"Handbook of Venoms and Toxins of Reptiles","author":"Guti\u00e9rrez J. M.","year":"2009"},{"key":"ref10\/cit10","first-page":"229","volume":"17","author":"Otero R.","year":"1992","journal-title":"Acta M\u00e9d. Colomb."},{"key":"ref11\/cit11","first-page":"383","volume":"79","author":"Dao L.","year":"1971","journal-title":"Gaceta M\u00e9d. Caracas"},{"key":"ref12\/cit12","doi-asserted-by":"crossref","first-page":"1639","DOI":"10.1016\/S0041-0101(97)00046-9","volume":"35","author":"Rojas G.","year":"1997","journal-title":"Toxicon"},{"key":"ref13\/cit13","doi-asserted-by":"crossref","first-page":"23","DOI":"10.51481\/amc.v41i4.528","volume":"41","author":"Arroyo O.","year":"1999","journal-title":"Acta M\u00e9d. Costarricense"},{"key":"ref14\/cit14","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/S0041-0101(02)00172-1","volume":"41","author":"Sasa M.","year":"2003","journal-title":"Toxicon"},{"key":"ref15\/cit15","doi-asserted-by":"crossref","first-page":"530","DOI":"10.1016\/j.toxicon.2008.06.018","volume":"52","author":"Fern\u00e1ndez P.","year":"2008","journal-title":"Toxicon"},{"key":"ref16\/cit16","volume-title":"The Venomous Reptiles of the Western Hemisphere","author":"Warrell D. A.","year":"2004"},{"key":"ref17\/cit17","doi-asserted-by":"crossref","first-page":"998","DOI":"10.1016\/j.toxicon.2009.07.001","volume":"54","author":"Otero-Pati\u00f1o R.","year":"2009","journal-title":"Toxicon"},{"key":"ref18\/cit18","doi-asserted-by":"crossref","first-page":"958","DOI":"10.1016\/j.toxicon.2009.01.038","volume":"54","author":"Guti\u00e9rrez J. M.","year":"2009","journal-title":"Toxicon"},{"key":"ref19\/cit19","doi-asserted-by":"crossref","first-page":"976","DOI":"10.1016\/j.toxicon.2009.01.039","volume":"54","author":"Guti\u00e9rrez J. M.","year":"2009","journal-title":"Toxicon"},{"key":"ref20\/cit20","doi-asserted-by":"crossref","first-page":"1107","DOI":"10.1016\/S0041-0101(02)00104-6","volume":"40","author":"Otero R.","year":"2002","journal-title":"Toxicon"},{"key":"ref21\/cit21","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1081\/CLT-120021113","volume":"41","author":"Lalloo D. G.","year":"2003","journal-title":"J. Toxicol.- Clin. Toxicol."},{"key":"ref22\/cit22","volume-title":"Animal Toxins: State of the Art. Perspectives in Health and Biotechnology","author":"Guti\u00e9rrez J. M.","year":"2009"},{"key":"ref23\/cit23","doi-asserted-by":"crossref","first-page":"1736","DOI":"10.1016\/j.febslet.2009.03.029","volume":"583","author":"Calvete J. J.","year":"2009","journal-title":"FEBS Lett."},{"key":"ref24\/cit24","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/j.jprot.2009.01.008","volume":"72","author":"Guti\u00e9rrez J. M.","year":"2009","journal-title":"J. Proteomics"},{"key":"ref25\/cit25","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/0041-0101(64)90017-0","volume":"2","author":"Jim\u00e9nez-Porras J. M.","year":"1964","journal-title":"Toxicon"},{"key":"ref26\/cit26","first-page":"341","volume":"28","author":"Guti\u00e9rrez J. M.","year":"1980","journal-title":"Rev. Biol. Trop."},{"key":"ref27\/cit27","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1016\/0041-0101(81)90076-3","volume":"19","author":"Arag\u00f3n F.","year":"1981","journal-title":"Toxicon"},{"key":"ref28\/cit28","doi-asserted-by":"crossref","first-page":"3556","DOI":"10.1021\/pr800332p","volume":"7","author":"Alape-Gir\u00f3n A.","year":"2008","journal-title":"J. Proteome Res."},{"key":"ref29\/cit29","doi-asserted-by":"crossref","first-page":"2445","DOI":"10.1021\/pr8000139","volume":"7","author":"Lomonte B.","year":"2008","journal-title":"J. Proteome Res."},{"key":"ref30\/cit30","doi-asserted-by":"crossref","first-page":"4396","DOI":"10.1021\/pr8003826","volume":"7","author":"Guti\u00e9rrez J. M.","year":"2008","journal-title":"J. Proteome Res."},{"key":"ref31\/cit31","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/j.jprot.2009.01.005","volume":"72","author":"Calvete J. J.","year":"2009","journal-title":"J. Proteomics"},{"key":"ref32\/cit32","volume-title":"Natural Toxins. Animal, Plant and Microbial","author":"Theakston R. D. G.","year":"1986"},{"key":"ref33\/cit33","volume-title":"Envenomings and Their Treatments","author":"Guti\u00e9rrez J. M.","year":"1996"},{"key":"ref34\/cit34","volume-title":"Determinaci\u00f3n de Actividades T\u00f3xicas de Venenos de Serpientes y su Neutralizaci\u00f3n por Antivenenos. Manual de M\u00e9todos de Laboratorio","year":"2008"},{"key":"ref35\/cit35","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/0041-0101(94)90087-6","volume":"32","author":"Rojas G.","year":"1994","journal-title":"Toxicon"},{"key":"ref36\/cit36","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/S0041-0101(96)00077-3","volume":"35","author":"Angulo Y.","year":"1997","journal-title":"Toxicon"},{"key":"ref37\/cit37","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1007\/BF01025307","volume":"9","author":"Syu W. J.","year":"1990","journal-title":"J. Protein Chem."},{"key":"ref38\/cit38","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1038\/227680a0","volume":"227","author":"Laemmli U. K.","year":"1970","journal-title":"Nature"},{"key":"ref39\/cit39","doi-asserted-by":"crossref","first-page":"4350","DOI":"10.1073\/pnas.76.9.4350","volume":"76","author":"Towbin H.","year":"1979","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"ref40\/cit40","doi-asserted-by":"crossref","first-page":"3389","DOI":"10.1093\/nar\/25.17.3389","volume":"25","author":"Altschul S. F.","year":"1997","journal-title":"Nucleic Acids Res."},{"key":"ref41\/cit41","doi-asserted-by":"crossref","first-page":"859","DOI":"10.1002\/pmic.200300415","volume":"3","author":"Le Blanc J. C.","year":"2003","journal-title":"Proteomics"},{"key":"ref42\/cit42","volume-title":"Manual de T\u00e9cnicas de Laboratorio. Qu\u00edmica Cl\u00ednica","author":"Schosinsky K.","year":"1983"},{"key":"ref43\/cit43","doi-asserted-by":"crossref","first-page":"1429","DOI":"10.1016\/S0041-0101(99)00236-6","volume":"38","author":"Bogar\u00edn G.","year":"2000","journal-title":"Toxicon"},{"key":"ref44\/cit44","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1016\/S0041-0101(03)00043-6","volume":"41","author":"Arce V.","year":"2003","journal-title":"Toxicon"},{"key":"ref45\/cit45","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/j.actatropica.2004.09.008","volume":"93","author":"Rojas E.","year":"2005","journal-title":"Acta Tropica"},{"key":"ref46\/cit46","doi-asserted-by":"crossref","first-page":"1127","DOI":"10.1016\/0041-0101(90)90110-S","volume":"28","author":"Guti\u00e9rrez J. M.","year":"1990","journal-title":"Toxicon"},{"key":"ref47\/cit47","doi-asserted-by":"crossref","first-page":"841","DOI":"10.1016\/0041-0101(89)90096-2","volume":"27","author":"Gen\u00e9 J. A.","year":"1989","journal-title":"Toxicon"},{"key":"ref48\/cit48","doi-asserted-by":"crossref","first-page":"887","DOI":"10.1016\/0041-0101(85)90380-0","volume":"23","author":"Guti\u00e9rrez J. M.","year":"1985","journal-title":"Toxicon"},{"key":"ref49\/cit49","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1016\/j.bbrc.2004.09.031","volume":"324","author":"Wang W. J.","year":"2004","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"ref50\/cit50","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/0300-9629(86)90058-7","volume":"84","author":"Guti\u00e9rrez J. M.","year":"1986","journal-title":"Comp. Biochem. Physiol."},{"key":"ref51\/cit51","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1016\/S0041-0101(02)00393-8","volume":"41","author":"Theakston R. D. G.","year":"2003","journal-title":"Toxicon"},{"key":"ref52\/cit52","doi-asserted-by":"crossref","first-page":"1099","DOI":"10.1016\/0041-0101(92)90055-A","volume":"30","author":"Chaves F.","year":"1992","journal-title":"Toxicon"},{"key":"ref53\/cit53","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/0041-0101(94)00138-X","volume":"33","author":"Guti\u00e9rrez J. M.","year":"1995","journal-title":"Toxicon"},{"key":"ref54\/cit54","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/S0041-0101(99)00127-0","volume":"38","author":"Franceschi A.","year":"2000","journal-title":"Toxicon"},{"key":"ref55\/cit55","doi-asserted-by":"crossref","first-page":"1137","DOI":"10.1016\/0041-0101(93)90129-7","volume":"31","author":"Borkow G.","year":"1993","journal-title":"Toxicon"},{"key":"ref56\/cit56","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/S0003-9861(03)00385-0","volume":"418","author":"Lor\u00eda G. D.","year":"2003","journal-title":"Arch. Biochem. Biophys."},{"key":"ref57\/cit57","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1016\/j.toxicon.2004.01.016","volume":"43","author":"Rucavado A.","year":"2004","journal-title":"Toxicon"},{"key":"ref58\/cit58","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1160\/TH05-02-0112","volume":"94","author":"Rucavado A.","year":"2005","journal-title":"Thromb. Haemost."},{"key":"ref59\/cit59","volume-title":"Handbook of Venoms and Toxins of Reptiles","author":"Guti\u00e9rrez J. M.","year":"2009"},{"key":"ref60\/cit60","doi-asserted-by":"crossref","first-page":"1405","DOI":"10.1016\/0041-0101(95)00085-Z","volume":"33","author":"Guti\u00e9rrez J. M.","year":"1995","journal-title":"Toxicon"},{"key":"ref61\/cit61","doi-asserted-by":"crossref","first-page":"1861","DOI":"10.1016\/S0041-0101(98)00107-X","volume":"36","author":"Chaves F.","year":"1998","journal-title":"Toxicon"},{"key":"ref62\/cit62","doi-asserted-by":"crossref","first-page":"841","DOI":"10.1016\/S0300-9084(00)01163-9","volume":"82","author":"Guti\u00e9rrez J. M.","year":"2000","journal-title":"Biochimie"},{"key":"ref63\/cit63","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1006\/exmp.1995.1042","volume":"63","author":"Rucavado A.","year":"1995","journal-title":"Exp. Mol. Pathol."},{"key":"ref64\/cit64","first-page":"245","volume":"79","author":"Rucavado A.","year":"1998","journal-title":"Int. J. Exp. Pathol."},{"key":"ref65\/cit65","doi-asserted-by":"crossref","first-page":"2421","DOI":"10.1038\/jid.2008.118","volume":"128","author":"Jim\u00e9nez N.","year":"2008","journal-title":"J. Invest. Dermatol."},{"key":"ref66\/cit66","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/j.toxicon.2003.11.012","volume":"43","author":"Escalante T.","year":"2004","journal-title":"Toxicon"},{"key":"ref67\/cit67","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1016\/j.vaccine.2008.10.066","volume":"27","author":"Arce-Estrada V.","year":"2009","journal-title":"Vaccine"},{"key":"ref68\/cit68","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1046\/j.1365-2249.2000.01287.x","volume":"121","author":"Harrison R. A.","year":"2000","journal-title":"Clin. Exp. Immunol."},{"key":"ref69\/cit69","doi-asserted-by":"crossref","first-page":"e184","DOI":"10.1371\/journal.pmed.0030184","volume":"3","author":"Wagstaff S. C.","year":"2006","journal-title":"PLoS Med."},{"key":"ref70\/cit70","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.jprot.2009.07.013","volume":"73","author":"N\u00fa\u00f1ez V.","year":"2009","journal-title":"J. Proteomics"}],"container-title":["Journal of Proteome Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/pr9009518","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,3,9]],"date-time":"2023-03-09T13:15:45Z","timestamp":1678367745000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/pr9009518"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,11,24]]},"references-count":70,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2010,1,4]]}},"alternative-id":["10.1021\/pr9009518"],"URL":"https:\/\/doi.org\/10.1021\/pr9009518","relation":{},"ISSN":["1535-3893","1535-3907"],"issn-type":[{"value":"1535-3893","type":"print"},{"value":"1535-3907","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,11,24]]}}}