{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,2]],"date-time":"2025-12-02T15:10:39Z","timestamp":1764688239473},"reference-count":59,"publisher":"American Chemical Society (ACS)","issue":"8","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Chem. Res. Toxicol."],"published-print":{"date-parts":[[2000,8,1]]},"DOI":"10.1021\/tx0000116","type":"journal-article","created":{"date-parts":[[2002,7,26]],"date-time":"2002-07-26T05:54:00Z","timestamp":1027662840000},"page":"742-748","source":"Crossref","is-referenced-by-count":58,"title":["Permeability, Cytotoxicity, and Genotoxicity of Cr(III) Complexes and Some Cr(V) Analogues in V79 Chinese Hamster Lung Cells"],"prefix":"10.1021","volume":"13","author":[{"given":"Carolyn T.","family":"Dillon","sequence":"first","affiliation":[{"name":"Centre for Heavy Metals Research, School of Chemistry, The University of Sydney, NSW 2006, Australia, National Occupational Health and Safety Commission (NOHSC), P.O. Box 58, Sydney, NSW 2001, Australia, Micro Analytical Research Centre, School of Physics, The University of Melbourne, Parkville 3052, Australia, and Institute of Nuclear Physics, Cracow, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter A.","family":"Lay","sequence":"additional","affiliation":[{"name":"Centre for Heavy Metals Research, School of Chemistry, The University of Sydney, NSW 2006, Australia, National Occupational Health and Safety Commission (NOHSC), P.O. Box 58, Sydney, NSW 2001, Australia, Micro Analytical Research Centre, School of Physics, The University of Melbourne, Parkville 3052, Australia, and Institute of Nuclear Physics, Cracow, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonio M.","family":"Bonin","sequence":"additional","affiliation":[{"name":"Centre for Heavy Metals Research, School of Chemistry, The University of Sydney, NSW 2006, Australia, National Occupational Health and Safety Commission (NOHSC), P.O. Box 58, Sydney, NSW 2001, Australia, Micro Analytical Research Centre, School of Physics, The University of Melbourne, Parkville 3052, Australia, and Institute of Nuclear Physics, Cracow, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marian","family":"Cholewa","sequence":"additional","affiliation":[{"name":"Centre for Heavy Metals Research, School of Chemistry, The University of Sydney, NSW 2006, Australia, National Occupational Health and Safety Commission (NOHSC), P.O. Box 58, Sydney, NSW 2001, Australia, Micro Analytical Research Centre, School of Physics, The University of Melbourne, Parkville 3052, Australia, and Institute of Nuclear Physics, Cracow, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"George J. F.","family":"Legge","sequence":"additional","affiliation":[{"name":"Centre for Heavy Metals Research, School of Chemistry, The University of Sydney, NSW 2006, Australia, National Occupational Health and Safety Commission (NOHSC), P.O. Box 58, Sydney, NSW 2001, Australia, Micro Analytical Research Centre, School of Physics, The University of Melbourne, Parkville 3052, Australia, and Institute of Nuclear Physics, Cracow, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"316","published-online":{"date-parts":[[2000,7,26]]},"reference":[{"key":"tx0000116b00001\/tx0000116b00001_1","volume-title":"Biological and environmental aspects of chromium","author":"Lang\u00e5rd S.","year":"1982"},{"key":"tx0000116b00002\/tx0000116b00002_1","doi-asserted-by":"crossref","DOI":"10.1080\/07315724.1998.10718802","volume":"17","author":"Anderson R. A.","year":"1998","journal-title":"J. Am. Coll. Nutr."},{"key":"tx0000116b00003\/tx0000116b00003_1","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1080\/07315724.1999.10718821","volume":"18","author":"Vincent J. B.","year":"1999","journal-title":"J. Am. Coll. Nutr."},{"key":"tx0000116b00004\/tx0000116b00004_1","volume":"16","author":"Anderson R. A.","year":"1997","journal-title":"J. Am. Coll. Nutr."},{"key":"tx0000116b00005\/tx0000116b00005_1","volume-title":"Elevated intakes of supplemental chromium improve glucose and insulin variables in individuals with type 2 diabetes. Diabetes 46, 1786\u22121791","author":"Anderson R. A.","year":"1997"},{"key":"tx0000116b00006\/tx0000116b00006_1","doi-asserted-by":"crossref","DOI":"10.2527\/1997.75102661x","volume":"75","author":"Mooney K. W.","year":"1997","journal-title":"J. Anim. Sci."},{"key":"tx0000116b00007\/tx0000116b00007_1","doi-asserted-by":"crossref","DOI":"10.1093\/ajcn\/63.6.954","volume":"63","author":"Lukaski H. C.","year":"1996","journal-title":"Am. J. Clin. Nutr."},{"key":"tx0000116b00008\/tx0000116b00008_1","volume":"35","author":"Trent L. K.","year":"1995","journal-title":"J. Sport Med."},{"key":"tx0000116b00009\/tx0000116b00009_1","volume-title":"The nutritional supplement chromium(III) tris(picolinate) cleaves DNA. Chem. Res. Toxicol. 12, 483\u2212487","author":"Speetjens J. K.","year":"1999"},{"key":"tx0000116b00010\/tx0000116b00010_1","volume-title":"Comparative induction of oxidative stress in cultured J774A.1 macrophage cells by chromium picolinate and chromium nicotinate. Mol. Pathol. Pharmacol. 97, 335\u2212346","author":"Bagchi D.","year":"1997"},{"key":"tx0000116b00011\/tx0000116b00011_1","volume-title":"Mononuclear and binuclear chromium(III) picolinate complexes. Inorg. Chem. 31, 5178\u22125184","author":"Stearns D. M.","year":"1992"},{"key":"tx0000116b00012\/tx0000116b00012_1","volume":"9","author":"Stearns D. M.","year":"1995","journal-title":"FASEB J."},{"key":"tx0000116b00013\/tx0000116b00013_1","unstructured":"IARC (1990)IARC Monographs on the Evaluation of Carcinogenic Risk to Humans:\u2009 Chromium, Nickel and Welding, Vol. 49, pp 49\u2212508, International Agency for Research on Cancer, Lyon, France."},{"key":"tx0000116b00014\/tx0000116b00014_1","volume-title":"Chromium in the Natural and Human Environments","author":"Yassi A.","year":"1988"},{"key":"tx0000116b00015\/tx0000116b00015_1","volume-title":"Mutagenicity of a series of hexacoordinate chromium(III) compounds. Mutat. Res. 90, 111\u2212118","author":"Warren G.","year":"1981"},{"key":"tx0000116b00016\/tx0000116b00016_1","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1080\/02772248709357190","volume":"14","author":"Beyersmann D.","year":"1987","journal-title":"Toxicol. Environ. Chem."},{"key":"tx0000116b00017\/tx0000116b00017_1","volume-title":"Chem. Pharm. Bull. 27","author":"Hashimoto T.","year":"1979"},{"key":"tx0000116b00018\/tx0000116b00018_1","unstructured":"Dillon, C. T. (1995) The role of Cr(V) complexes in chromium-induced genotoxicities. Ph.D. Thesis, The University of Sydney, NSW, Australia."},{"key":"tx0000116b00019\/tx0000116b00019_1","author":"Dillon C. T.","year":"2000","journal-title":"Aust. J. Chem. (in press)."},{"key":"tx0000116b00020\/tx0000116b00020_1","doi-asserted-by":"crossref","DOI":"10.1123\/ijsn.2.2.111","volume":"2","author":"Lefavi R. C.","year":"1992","journal-title":"Int. J. Sport Nutr."},{"key":"tx0000116b00021\/tx0000116b00021_1","volume":"9","author":"Stearns D. M.","year":"1995","journal-title":"FASEB J."},{"key":"tx0000116b00022\/tx0000116b00022_1","volume-title":"Permeability, cytotoxicity, and genotoxicity of chromium(V) and chromium(VI) complexes in V79 Chinese hamster lung cells. Chem. Res. Toxicol. 11, 119\u2212129","author":"Dillon C. T.","year":"1998"},{"key":"tx0000116b00023\/tx0000116b00023_1","volume-title":"Tris(diamine)chromium(III) salts. Inorg. Synth. 13, 184\u2212186","author":"Gillard R. D.","year":"1972"},{"key":"tx0000116b00024\/tx0000116b00024_1","unstructured":"Murdoch, C. M. (1989) Chromium(III) and the glucose tolerance factor. Ph.D. Thesis, The University of Sydney, NSW, Australia."},{"key":"tx0000116b00025\/tx0000116b00025_1","doi-asserted-by":"crossref","first-page":"68","DOI":"10.3891\/acta.chem.scand.15-0062","volume":"15","author":"Inskeep R. G.","year":"1961","journal-title":"Acta Chem. Scand."},{"key":"tx0000116b00026\/tx0000116b00026_1","doi-asserted-by":"crossref","DOI":"10.1016\/0022-1902(61)80278-9","volume":"20","author":"Inskeep R. G.","year":"1961","journal-title":"J. Inorg. Nucl. Chem."},{"key":"tx0000116b00027\/tx0000116b00027_1","doi-asserted-by":"crossref","first-page":"1463","DOI":"10.1246\/bcsj.42.1463","volume":"42","author":"Yamada S.","year":"1969","journal-title":"Bull. Chem. Soc. Jpn."},{"key":"tx0000116b00028\/tx0000116b00028_1","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1016\/S0020-1693(00)95869-9","volume":"5","author":"Yamada S.","year":"1971","journal-title":"Inorg. Chim. Acta"},{"key":"tx0000116b00029\/tx0000116b00029_1","author":"Coggon P.","year":"1970","journal-title":"J. Chem. Soc., Sect. A, 3296\u22123303."},{"key":"tx0000116b00030\/tx0000116b00030_1","volume":"22","author":"Saha H. K.","year":"1983","journal-title":"Indian J. Chem., Sect. A"},{"key":"tx0000116b00031\/tx0000116b00031_1","doi-asserted-by":"crossref","DOI":"10.1016\/S0020-1693(00)82323-3","volume":"86","author":"Sulfab Y.","year":"1984","journal-title":"Inorg. Chim. Acta"},{"key":"tx0000116b00032\/tx0000116b00032_1","volume-title":"Synthesis and molecular structure of oxochromium(V) cations. Coordination with donor ligands. Inorg. Chem. 24, 4671\u22124679","author":"Srinivasan K.","year":"1985"},{"key":"tx0000116b00033\/tx0000116b00033_1","volume":"21","author":"Ford D. K.","year":"1958","journal-title":"J. Natl. Cancer Inst."},{"key":"tx0000116b00034\/tx0000116b00034_1","volume-title":"Sect. B 104, 317\u2212323.","author":"Cholewa M.","year":"1995"},{"key":"tx0000116b00035\/tx0000116b00035_1","first-page":"36","volume":"147","author":"Fenech M.","year":"1985","journal-title":"Mutat. Res."},{"key":"tx0000116b00036\/tx0000116b00036_1","volume-title":"Solutions to the kinetic problem in the micronucleus assay. Cytobios 43, 233\u2212246","author":"Fenech M.","year":"1985"},{"key":"tx0000116b00037\/tx0000116b00037_1","volume-title":"The in vitro micronucleus assay for detection of cytogenetic effects induced by mutagen-carcinogens:\u2009 comparison with the in vitro sister-chromatid exchange assay. Mutat. Res. 130, 273\u2212282","author":"Lasne C.","year":"1984"},{"key":"tx0000116b00038\/tx0000116b00038_1","volume-title":"Enhanced production of micronuclei by hexavalent chromium in cultured CHO cells. Bull. Environ. Contam. Toxicol. 49, 535\u2212540","author":"Howard W. R.","year":"1992"},{"key":"tx0000116b00039\/tx0000116b00039_1","volume-title":"Simultaneous detection of chromosomal aberrations and sister-chromatid exchanges. Experience with DNA intercalating agents. Mutat. Res. 78, 253\u2212260","author":"Raj A. S.","year":"1980"},{"key":"tx0000116b00040\/tx0000116b00040_1","volume-title":"Principles of Biostatistics","author":"Pagano M.","year":"1993"},{"key":"tx0000116b00041\/tx0000116b00041_1","first-page":"97","volume":"30","author":"Hancock M. P.","year":"1976","journal-title":"Acta Chem. Scand., Sect. A"},{"key":"tx0000116b00042\/tx0000116b00042_1","first-page":"718","volume-title":"Comprehensive Coordination Chemistry","author":"Larkworthy L. F.","year":"1987"},{"key":"tx0000116b00043\/tx0000116b00043_1","author":"Lloret F.","year":"1989","journal-title":"J. Chem. Soc., Dalton Trans., 729\u2212738."},{"key":"tx0000116b00044\/tx0000116b00044_1","volume-title":"Substitution lability of chromium(III) complexes with ground-state distortion. Inorg. Chem. 19, 3181\u22123182","author":"Prasad D. R.","year":"1980"},{"key":"tx0000116b00045\/tx0000116b00045_1","volume-title":"Cr(Schiff base)(H2O)2+, and their conjugate bases with thiocyanate, azide, imidazole, pyridine and nicotinic acid as ligands. Inorg. Chem. 21, 850\u2212854.","author":"Prasad D. R.","year":"1982"},{"key":"tx0000116b00046\/tx0000116b00046_1","volume-title":"Cytotoxicity of chromium-III and -VI compounds. I. In vitro studies using different cell culture systems. Inhalation Toxicol. 5, 345\u2212369","author":"Popper H. H.","year":"1993"},{"key":"tx0000116b00047\/tx0000116b00047_1","volume":"29","author":"Gray S. J.","year":"1950","journal-title":"J. Clin. Invest."},{"key":"tx0000116b00048\/tx0000116b00048_1","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1080\/02772248709357191","volume":"14","author":"Kortenkamp A.","year":"1987","journal-title":"Toxicol. Environ. Chem."},{"key":"tx0000116b00049\/tx0000116b00049_1","doi-asserted-by":"crossref","unstructured":"Barr-David, G., Hambley, T. W., Irwin, J. A., Judd, R. J., Lay, P. A., Martin, B. D., Bramley, R., Dixon, N. E., Hendry, P., Ji, J.Y., Baker, R. S. U., and Bonin, A. M. (1992) Suppression by vanadium(IV) of chromium(V)-mediated DNA cleavage and chromium(VI\/V)-induced mutagenesis. Synthesis and crystal structure of the vanadium(IV) complex. (NH4)[V(O){HOC(Et)2COO}{OC(Et)2COO}].Inorg. Chem.31, 4906\u22124908.","DOI":"10.1021\/ic00050a002"},{"key":"tx0000116b00050\/tx0000116b00050_1","volume-title":"Role of valence state and solubility of chromium compounds on induction of cytotoxicity, mutagenesis and anchorage independence in diploid human fibroblasts. Cancer Res. 50, 7835\u22127842","author":"Biedermann K. A.","year":"1990"},{"key":"tx0000116b00051\/tx0000116b00051_1","doi-asserted-by":"crossref","DOI":"10.1038\/bjc.1978.58","volume":"37","author":"Levis A. G.","year":"1978","journal-title":"Br. J. Cancer"},{"key":"tx0000116b00052\/tx0000116b00052_1","volume-title":"Carcinogenesis 14","author":"Dillon C. T.","year":"1993"},{"key":"tx0000116b00053\/tx0000116b00053_1","doi-asserted-by":"crossref","unstructured":"Collins, T. J., Slebodnick, C., and Uffelman, E. S. (1990) Chromium(V)-oxo complexes of macrocyclic tetraamido-Nligands tailored for highly oxidized middle transition metal complexes:\u2009 a new18O-labeling reagent and a structure with four nonplanar amides.Inorg. Chem.29, 3433\u22123436.","DOI":"10.1021\/ic00343a030"},{"key":"tx0000116b00054\/tx0000116b00054_1","volume-title":"Structural identification of valine hydroperoxides and hydroxides on radical-damaged amino acid, peptide and protein molecules. Free Radical Biol. Med. 19, 281\u2212292","author":"Fu S. L.","year":"1995"},{"key":"tx0000116b00055\/tx0000116b00055_1","doi-asserted-by":"crossref","DOI":"10.1042\/bj3050643","volume":"305","author":"Davies M. J.","year":"1995","journal-title":"Biochem. J."},{"key":"tx0000116b00056\/tx0000116b00056_1","volume":"311","author":"Fu S. L.","year":"1995","journal-title":"Biochem. J."},{"key":"tx0000116b00057\/tx0000116b00057_1","first-page":"51","volume":"20","author":"Soszynski M.","year":"1996","journal-title":"Free Radical Biol. Med."},{"key":"tx0000116b00058\/tx0000116b00058_1","volume-title":"An oxygen dependence in chromium mutagenesis. Mutat. Res. 244, 239\u2212244","author":"Sugden K. D.","year":"1990"},{"key":"tx0000116b00059\/tx0000116b00059_1","volume-title":"Oxygen radical-mediated DNA damage by redox active Cr(III) complexes. Biochemistry 31, 11626\u221211631","author":"Sugden K. D.","year":"1992"}],"container-title":["Chemical Research in Toxicology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/tx0000116","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,6]],"date-time":"2023-04-06T09:39:09Z","timestamp":1680773949000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/tx0000116"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2000,7,26]]},"references-count":59,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2000,8,1]]}},"alternative-id":["10.1021\/tx0000116"],"URL":"https:\/\/doi.org\/10.1021\/tx0000116","relation":{},"ISSN":["0893-228X","1520-5010"],"issn-type":[{"value":"0893-228X","type":"print"},{"value":"1520-5010","type":"electronic"}],"subject":[],"published":{"date-parts":[[2000,7,26]]}}}