{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T21:31:04Z","timestamp":1762032664471},"reference-count":56,"publisher":"American Chemical Society (ACS)","issue":"7","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Chem. Res. Toxicol."],"published-print":{"date-parts":[[2003,7,1]]},"DOI":"10.1021\/tx034077n","type":"journal-article","created":{"date-parts":[[2007,5,31]],"date-time":"2007-05-31T13:49:24Z","timestamp":1180619364000},"page":"881-892","source":"Crossref","is-referenced-by-count":21,"title":["Oxochromium(V) Species Formed with 2,3-Dehydro-2-deoxy-<i>N<\/i>-acetylneuraminic or <i>N<\/i>-Acetylneuraminic (Sialic) Acids:\u2009 An In Vitro Model System of Oxochromium(V) Species Potentially Stabilized in the Respiratory Tract upon Inhalation of Carcinogenic Chromium(VI) Compounds"],"prefix":"10.1021","volume":"16","author":[{"given":"Rachel","family":"Codd","sequence":"first","affiliation":[{"name":"Centre for Heavy Metals Research, School of Chemistry, University of Sydney, NSW 2006, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter A.","family":"Lay","sequence":"additional","affiliation":[{"name":"Centre for Heavy Metals Research, School of Chemistry, University of Sydney, NSW 2006, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"316","published-online":{"date-parts":[[2003,7,1]]},"reference":[{"key":"tx034077nb00001\/tx034077nb00001_1","first-page":"198","volume-title":"IARC Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Humans","volume":"49","author":"IARC","year":"1990"},{"key":"tx034077nb00002\/tx034077nb00002_1","volume-title":"A402\u2212A407.","author":"Pellerin C.","year":"2000"},{"key":"tx034077nb00003\/tx034077nb00003_1","author":"Gibb H. J.","year":"2000","journal-title":"Am. J. Ind. Med., 115\u2212126."},{"key":"tx034077nb00004\/tx034077nb00004_1","volume-title":"Chromium in biology:\u2009 toxicology and nutritional aspects. Prog. Inorg. Chem. 51, 145\u2212250","author":"Levina A.","year":"2003"},{"key":"tx034077nb00005\/tx034077nb00005_1","volume-title":"Chromium(V)-induced cleavage of DNA:\u2009 are chromium(V) complexes the active carcinogens in chromium(VI)-induced cancers? Chem. Res. Toxicol. 2, 227\u2212229","author":"Farrell R. P.","year":"1989"},{"key":"tx034077nb00006\/tx034077nb00006_1","volume-title":"vitro plasmid DNA cleavage by chromium(V) and -(IV) 2-hydroxycarboxylato complexes. Chem. Res. Toxicol. 12, 371\u2212381","author":"Levina A.","year":"1999"},{"key":"tx034077nb00007\/tx034077nb00007_1","volume-title":"Disproportionation and nuclease activity of bis[2-ethyl-2-hydroxybutanoato(2\u2212)]oxochromate(V) in neutral aqueous solutions. Inorg. Chem. 39, 385\u2212395","author":"Levina A.","year":"2000"},{"key":"tx034077nb00008\/tx034077nb00008_1","volume-title":"Permeability, cytotoxicity and genotoxicity of Cr(III) complexes and some Cr(V) analogues in V79 Chinese hamster lung cells. Chem. Res. Toxicol. 13, 742\u2212748","author":"Dillon C. T.","year":"2000"},{"key":"tx034077nb00009\/tx034077nb00009_1","doi-asserted-by":"crossref","DOI":"10.1071\/CH00006","volume":"53","author":"Dillon C. T.","year":"2000","journal-title":"Aust. J. Chem."},{"key":"tx034077nb00010\/tx034077nb00010_1","doi-asserted-by":"crossref","DOI":"10.1039\/ft9959101207","volume":"91","author":"Barr-David G.","year":"1995","journal-title":"J. Chem. Soc., Faraday Trans."},{"key":"tx034077nb00011\/tx034077nb00011_1","volume-title":"Sialoglycoprotein and carbohydrate complexes in chromium toxicity. Curr. Opin. Chem. Biol. 7, 213\u2212219","author":"Codd R.","year":"2003"},{"key":"tx034077nb00012\/tx034077nb00012_1","author":"Rizzotto M.","year":"2002","journal-title":"J. Chem. Soc., Dalton Trans., 3206\u22123213."},{"key":"tx034077nb00013\/tx034077nb00013_1","doi-asserted-by":"crossref","DOI":"10.1021\/ja9909780","volume":"121","author":"Codd R.","year":"1999","journal-title":"J. Am. Chem. Soc."},{"key":"tx034077nb00014\/tx034077nb00014_1","doi-asserted-by":"crossref","DOI":"10.1021\/cr000407m","volume":"102","author":"Angata T.","year":"2002","journal-title":"Chem. Rev."},{"key":"tx034077nb00015\/tx034077nb00015_1","volume-title":"Structure, function and metabolism of sialic acids. Cell. Mol. Life Sci. 54, 1330\u22121349","author":"Traving C.","year":"1998"},{"key":"tx034077nb00016\/tx034077nb00016_1","doi-asserted-by":"crossref","DOI":"10.1021\/ja0160501","volume":"123","author":"Codd R.","year":"2001","journal-title":"J. Am. Chem. Soc."},{"key":"tx034077nb00017\/tx034077nb00017_1","first-page":"50","volume-title":"Sialic Acids. Chemistry, Metabolism and Function","author":"Corfield A. P.","year":"1982"},{"key":"tx034077nb00018\/tx034077nb00018_1","volume-title":"Biology of the Sialic Acids","author":"Schauer R.","year":"1995"},{"key":"tx034077nb00019\/tx034077nb00019_1","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1002\/j.1460-2075.1992.tb05026.x","volume":"11","author":"Burmeister W. P.","year":"1992","journal-title":"EMBO J."},{"key":"tx034077nb00020\/tx034077nb00020_1","doi-asserted-by":"crossref","DOI":"10.1021\/cr000414a","volume":"102","author":"Kiefel M. J.","year":"2002","journal-title":"Chem. Rev."},{"key":"tx034077nb00021\/tx034077nb00021_1","volume-title":"The synthesis of 2,3-didehydro-2,4-dideoxy-4-guanidinyl-N-acetylneuraminic acid: a potent influenza virus sialidase inhibitor. Carbohydr. Res. 259, 301\u2212305","author":"von Itzstein M.","year":"1994"},{"key":"tx034077nb00022\/tx034077nb00022_1","doi-asserted-by":"crossref","DOI":"10.1046\/j.1365-2362.1999.00485.x","volume":"29","author":"Sillanaukee P.","year":"1999","journal-title":"Eur. J. Clin. Invest."},{"key":"tx034077nb00023\/tx034077nb00023_1","doi-asserted-by":"crossref","DOI":"10.1016\/S0021-9258(17)40194-3","volume":"252","author":"Jaques L. W.","year":"1977","journal-title":"J. Biol. Chem."},{"key":"tx034077nb00024\/tx034077nb00024_1","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1016\/S0008-6215(00)85360-4","volume":"83","author":"Jaques L. W.","year":"1980","journal-title":"Carbohydr. Res."},{"key":"tx034077nb00025\/tx034077nb00025_1","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1016\/S0162-0134(01)00322-1","volume":"88","author":"Saladini M.","year":"2002","journal-title":"J. Inorg. Biochem."},{"key":"tx034077nb00026\/tx034077nb00026_1","volume-title":"Permeability, cytotoxicity, and genotoxicity of chromium(V) and chromium(VI) complexes in V79 chinese hamster lung cells. Chem. Res. Toxicol. 11, 119\u2212129","author":"Dillon C. T.","year":"1998"},{"key":"tx034077nb00027\/tx034077nb00027_1","doi-asserted-by":"crossref","DOI":"10.1006\/jmrb.1994.1062","volume":"104","author":"Duling D. R.","year":"1994","journal-title":"J. Magn. Reson."},{"key":"tx034077nb00028\/tx034077nb00028_1","volume-title":"Version 0.96","author":"Win SIM","year":"1995"},{"key":"tx034077nb00029\/tx034077nb00029_1","volume":"217","author":"Codd R.","year":"2001","journal-title":"Coord. Chem. Rev. 216\u2212"},{"key":"tx034077nb00030\/tx034077nb00030_1","volume-title":"Role of chromium(V), glutathione thiyl radical and hydroxyl radical intermediates in chromium(VI)-induced DNA damage. Toxicol. Environ. Chem. 22, 135\u2212148","author":"Aiyar J.","year":"1989"},{"key":"tx034077nb00031\/tx034077nb00031_1","volume-title":"Structure and reactivity of a chromium(V) glutathione complex. Inorg. Chem. 42, 767\u2212784","author":"Levina A.","year":"2003"},{"key":"tx034077nb00032\/tx034077nb00032_1","doi-asserted-by":"crossref","DOI":"10.1021\/ja00300a035","volume":"107","author":"Connett P. H.","year":"1985","journal-title":"J. Am. Chem. Soc."},{"key":"tx034077nb00033\/tx034077nb00033_1","doi-asserted-by":"crossref","unstructured":"Bramley, R., Ji, J.Y., and Lay, P. A. (1991) Ligand-exchange reactions of chromium(V):\u2009 characterization of the ligand-exchange equilibria of bis(2-ethyl-2-hydroxybutanoato(2\u2212))oxochromate(V) in aqueous 1,2-ethanediol and the solution structure of bis(1,2-ethanediolato(2\u2212))oxochromate(V).Inorg. Chem.30, 1557\u22121564.","DOI":"10.1021\/ic00007a025"},{"key":"tx034077nb00034\/tx034077nb00034_1","first-page":"86","volume":"40","author":"Headlam H. A.","year":"2001","journal-title":"Inorg. Chem."},{"key":"tx034077nb00035\/tx034077nb00035_1","unstructured":"Advanced Chemistry Development (ACD) Software Solaris V4.67 (1994\u22122002). The larger pKavalue ofI, relative toII, is most likely due to the increased delocalization of the negative charge inIIover the \u03b1-keto or the \u03b1-hemiacetal group (40)."},{"key":"tx034077nb00036\/tx034077nb00036_1","volume-title":"Characterization and X-ray absorption spectroscopic studies of bis[quinato(2\u2212)]oxochromate(V). Inorg. Chem. 39, 990\u2212997","author":"Codd R.","year":"2000"},{"key":"tx034077nb00037\/tx034077nb00037_1","volume-title":"Solvent dependence of the EPR spectra of oxochromate(V) complexes:\u2009 solution structures and the effects of hydrogen bonding between the solvent and the complex. Inorg. Chem. 29, 3089\u22123094","author":"Bramley R.","year":"1990"},{"key":"tx034077nb00038\/tx034077nb00038_1","doi-asserted-by":"crossref","DOI":"10.1021\/ja00469a025","volume":"100","author":"Krumpol\u0109 M.","year":"1978","journal-title":"J. Am. Chem. Soc."},{"key":"tx034077nb00039\/tx034077nb00039_1","author":"Judd R. J.","year":"1989","journal-title":"J. Chem. Soc., Dalton Trans., 2205\u22122210."},{"key":"tx034077nb00040\/tx034077nb00040_1","volume":"47","author":"Hurd C. D.","year":"1970","journal-title":"J. Chem. Educ."},{"key":"tx034077nb00041\/tx034077nb00041_1","volume":"22","author":"Friebolin H.","year":"1981","journal-title":"Tetrahedron Lett."},{"key":"tx034077nb00042\/tx034077nb00042_1","author":"Signorella S.","year":"2001","journal-title":"Eur. J. Inorg. Chem., 1829\u22121833."},{"key":"tx034077nb00043\/tx034077nb00043_1","doi-asserted-by":"crossref","DOI":"10.1042\/bj0610298","volume":"61","author":"Gottschalk A.","year":"1955","journal-title":"Biochem. J."},{"key":"tx034077nb00044\/tx034077nb00044_1","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1007\/BF01962876","volume":"22","author":"Castells M. T.","year":"1990","journal-title":"Histochem. J."},{"key":"tx034077nb00045\/tx034077nb00045_1","doi-asserted-by":"crossref","DOI":"10.1016\/S0378-5173(99)00442-1","volume":"198","author":"Washington N.","year":"2000","journal-title":"Int. J. Pharm."},{"key":"tx034077nb00046\/tx034077nb00046_1","doi-asserted-by":"crossref","unstructured":"Westerveld, G.J., Dekker, I., Voss, H.P., Bast, A., and Scheeren, R. A. (1997) Antioxidant levels in the nasal mucosa of patients with chromic sinusitis and healthy controls.Arch. Otolaryngol.123, 201\u2212204.","DOI":"10.1001\/archotol.1997.01900020089013"},{"key":"tx034077nb00047\/tx034077nb00047_1","doi-asserted-by":"crossref","DOI":"10.1016\/S0040-4039(01)86670-3","volume":"20","author":"Dabrowski U.","year":"1979","journal-title":"Tetrahedron Lett."},{"key":"tx034077nb00048\/tx034077nb00048_1","volume":"29","author":"Flippen J. L.","year":"1973","journal-title":"Acta Crystallogr., Sect. B"},{"key":"tx034077nb00049\/tx034077nb00049_1","volume-title":"Chem. Pharm. Bull. 36","author":"Furuhata K.","year":"1988"},{"key":"tx034077nb00050\/tx034077nb00050_1","doi-asserted-by":"crossref","DOI":"10.1021\/ja00420a031","volume":"98","author":"Czarniecki M. F.","year":"1976","journal-title":"J. Am. Chem. Soc."},{"key":"tx034077nb00051\/tx034077nb00051_1","volume":"399","author":"Brown E. B.","year":"1975","journal-title":"Biochim. Biophys. Acta"},{"key":"tx034077nb00052\/tx034077nb00052_1","volume":"29","author":"O'Connell A. M.","year":"1973","journal-title":"Acta Crystallogr., Sect. B"},{"key":"tx034077nb00053\/tx034077nb00053_1","volume-title":"EPR and proton ENDOR study of the solution equilibria of bis(2-ethyl-2-hydroxybutanoato(2\u2212))oxochromate(V) and bis(2-hydroxy-2-methylbutanoato(2\u2212))oxochromate(V). Inorg. Chem. 32, 578\u2212581","author":"Branca M.","year":"1993"},{"key":"tx034077nb00054\/tx034077nb00054_1","first-page":"45","volume":"24","author":"Pool-Zobel B. L.","year":"1994","journal-title":"Environ. Mol. Mutagen."},{"key":"tx034077nb00055\/tx034077nb00055_1","volume-title":"Cleavage of human orosomucoid by a chromium(V) species:\u2009 relevance in biotoxicity of chromium. Biochem. Biophys. Res. Commun. 279, 980\u2212983","author":"Shrivastava H. Y.","year":"2000"},{"key":"tx034077nb00056\/tx034077nb00056_1","volume":"369","author":"Shrivastava H. Y.","year":"2003","journal-title":"Chem. Phys. Lett."}],"container-title":["Chemical Research in Toxicology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/tx034077n","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,6]],"date-time":"2023-04-06T17:02:11Z","timestamp":1680800531000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/tx034077n"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003,7,1]]},"references-count":56,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2003,7,1]]}},"alternative-id":["10.1021\/tx034077n"],"URL":"https:\/\/doi.org\/10.1021\/tx034077n","relation":{},"ISSN":["0893-228X","1520-5010"],"issn-type":[{"value":"0893-228X","type":"print"},{"value":"1520-5010","type":"electronic"}],"subject":[],"published":{"date-parts":[[2003,7,1]]}}}