{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,20]],"date-time":"2026-02-20T01:27:31Z","timestamp":1771550851090,"version":"3.50.1"},"reference-count":29,"publisher":"American Chemical Society (ACS)","issue":"9","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Chem. Res. Toxicol."],"published-print":{"date-parts":[[2004,9,1]]},"DOI":"10.1021\/tx040001v","type":"journal-article","created":{"date-parts":[[2004,9,20]],"date-time":"2004-09-20T04:21:17Z","timestamp":1095654077000},"page":"1245-1250","source":"Crossref","is-referenced-by-count":64,"title":["Human Cytochrome P450 Enzyme Specificity for Bioactivation of Safrole to the Proximate Carcinogen 1\u2018-Hydroxysafrole"],"prefix":"10.1021","volume":"17","author":[{"given":"Suzanne M. 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Box 360, 3700 AJ Zeist, The Netherlands, Laboratory of Biochemistry, Wageningen University, Dreijenlaan 3, 6703 HA Wageningen, The Netherlands, WU\/TNO Centre for Food Toxicology, P.O. Box 8000, 6700 EA Wageningen, The Netherlands, and Department of Chemistry of..."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hanem M.","family":"Awad","sequence":"additional","affiliation":[{"name":"Division of Toxicology, Wageningen University, Tuinlaan 5, 6703 HE Wageningen, The Netherlands, Laboratory of Organic Chemistry, Wageningen University, Dreijenplein 8, 6703 HB Wageningen, The Netherlands, TNO Nutrition and Food Research, P. O. Box 360, 3700 AJ Zeist, The Netherlands, Laboratory of Biochemistry, Wageningen University, Dreijenlaan 3, 6703 HA Wageningen, The Netherlands, WU\/TNO Centre for Food Toxicology, P.O. 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Box 8000, 6700 EA Wageningen, The Netherlands, and Department of Chemistry of..."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gerrit M.","family":"Alink","sequence":"additional","affiliation":[{"name":"Division of Toxicology, Wageningen University, Tuinlaan 5, 6703 HE Wageningen, The Netherlands, Laboratory of Organic Chemistry, Wageningen University, Dreijenplein 8, 6703 HB Wageningen, The Netherlands, TNO Nutrition and Food Research, P. O. Box 360, 3700 AJ Zeist, The Netherlands, Laboratory of Biochemistry, Wageningen University, Dreijenlaan 3, 6703 HA Wageningen, The Netherlands, WU\/TNO Centre for Food Toxicology, P.O. Box 8000, 6700 EA Wageningen, The Netherlands, and Department of Chemistry of..."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ernst J. 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