{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T06:34:01Z","timestamp":1790836441086,"version":"4.1.0"},"reference-count":18,"publisher":"American Chemical Society (ACS)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Chem. Res. Toxicol."],"published-print":{"date-parts":[[2007,1,1]]},"DOI":"10.1021\/tx060232x","type":"journal-article","created":{"date-parts":[[2006,12,9]],"date-time":"2006-12-09T07:01:23Z","timestamp":1165647683000},"page":"108-113","source":"Crossref","is-referenced-by-count":73,"title":["Quantitation of an Acetaldehyde Adduct in Human Leukocyte DNA and the Effect of Smoking Cessation"],"prefix":"10.1021","volume":"20","author":[{"given":"Li","family":"Chen","sequence":"first","affiliation":[{"name":"The Cancer Center and Transdisciplinary Tobacco Use Research Center, University of Minnesota, Minneapolis, Minnesota 55455"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mingyao","family":"Wang","sequence":"additional","affiliation":[{"name":"The Cancer Center and Transdisciplinary Tobacco Use Research Center, University of Minnesota, Minneapolis, Minnesota 55455"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter W.","family":"Villalta","sequence":"additional","affiliation":[{"name":"The Cancer Center and Transdisciplinary Tobacco Use Research Center, University of Minnesota, Minneapolis, Minnesota 55455"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xianghua","family":"Luo","sequence":"additional","affiliation":[{"name":"The Cancer Center and Transdisciplinary Tobacco Use Research Center, University of Minnesota, Minneapolis, Minnesota 55455"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rachel","family":"Feuer","sequence":"additional","affiliation":[{"name":"The Cancer Center and Transdisciplinary Tobacco Use Research Center, University of Minnesota, Minneapolis, Minnesota 55455"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joni","family":"Jensen","sequence":"additional","affiliation":[{"name":"The Cancer Center and Transdisciplinary Tobacco Use Research Center, University of Minnesota, Minneapolis, Minnesota 55455"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dorothy K.","family":"Hatsukami","sequence":"additional","affiliation":[{"name":"The Cancer Center and Transdisciplinary Tobacco Use Research Center, University of Minnesota, Minneapolis, Minnesota 55455"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen S.","family":"Hecht","sequence":"additional","affiliation":[{"name":"The Cancer Center and Transdisciplinary Tobacco Use Research Center, University of Minnesota, Minneapolis, Minnesota 55455"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2006,12,9]]},"reference":[{"key":"tx060232xb00001\/tx060232xb00001_1","unstructured":"U.S. Department of Health and Human Services. (2004)\n                      Report on Carcinogens\n                      , 11th ed. pp III-1\u2212III-3, Research Triangle Park, NC."},{"key":"tx060232xb00002\/tx060232xb00002_1","first-page":"132","volume-title":"Aldehydes, Epoxides and Peroxides. In IARC Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Humans","volume":"36","author":"International Agency for Research on Cancer","year":"1985"},{"key":"tx060232xb00003\/tx060232xb00003_1","first-page":"335","volume-title":"IARC Monographs on the Evaluation of Carcinogenic Risks to Humans","author":"International Agency for Research on Cancer","year":"1999"},{"key":"tx060232xb00004\/tx060232xb00004_1","volume-title":"Identification of DNA adducts of acetaldehyde. Chem. Res. Toxicol. 13, 1149\u22121157","author":"Wang M.","year":"2000"},{"key":"tx060232xb00005\/tx060232xb00005_1","volume-title":"Identification of an acetaldehyde adduct in human liver DNA and quantitation as N2-ethyldeoxyguanosine. Chem. Res. Toxicol. 19, 319\u2212324","author":"Wang M.","year":"2006"},{"key":"tx060232xb00006\/tx060232xb00006_1","doi-asserted-by":"crossref","unstructured":"Chepiga, T. A., Morton, M. J., Murphy, P. A., Avalos, J. T., Bombick, B. R., Doolittle, D. J., Borgerding, M. F., and Swauger, J. E. (2000) A comparison of the mainstream smoke chemistry and mutagenicity of a representative sample of the US cigarette market with two Kentucky reference cigarettes (K1R4F and K1R5F).\n                      Food Chem. Toxicol.\n                      38\n                      , 949\u2212962.","DOI":"10.1016\/S0278-6915(00)00086-7"},{"key":"tx060232xb00007\/tx060232xb00007_1","first-page":"102","volume-title":"IARC Monographs on the Evaluation of Carcinogenic Risks to Humans","volume":"83","author":"International Agency for Research on Cancer.","year":"2004"},{"key":"tx060232xb00008\/tx060232xb00008_1","volume-title":"Biomarkers Prev. 12, 1257\u22121261.","author":"Carmella S. G.","year":"2003"},{"key":"tx060232xb00009\/tx060232xb00009_1","volume-title":"Detection of DNA adducts of acetaldehyde in peripheral white blood cells of alcohol abusers. Carcinogenesis 18, 627\u2212632","author":"Fang J. L.","year":"1997"},{"key":"tx060232xb00010\/tx060232xb00010_1","volume-title":"Quantitation of urinary metabolites of a tobacco-specific lung carcinogen after smoking cessation. Cancer Res. 59, 590\u2212596","author":"Hecht S. S.","year":"1999"},{"key":"tx060232xb00011\/tx060232xb00011_1","first-page":"1187","volume-title":"IARC Monographs on the Evaluation of Carcinogenic Risks to Humans","volume":"83","author":"International Agency for Research on Cancer","year":"2004"},{"key":"tx060232xb00012\/tx060232xb00012_1","volume":"97","author":"Baquet C. R.","year":"2005","journal-title":"J Natl. Med. Assoc."},{"key":"tx060232xb00013\/tx060232xb00013_1","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1093\/aje\/kwh003","volume":"159","author":"Brennan P.","year":"2004","journal-title":"Am. J. Epidemiol."},{"key":"tx060232xb00014\/tx060232xb00014_1","volume-title":"Biomarkers Prev. 12, 1227\u22121233.","author":"Yokoyama T.","year":"2003"},{"key":"tx060232xb00015\/tx060232xb00015_1","volume-title":"Genetic and environmental influences on alcohol metabolism in humans. Alcohol Clin. Exp. Res. 25, 136\u2212144","author":"Li T. K.","year":"2001"},{"key":"tx060232xb00016\/tx060232xb00016_1","volume-title":"Reactions of 2,6-dimethyl-1,3-dioxane-4-ol (aldoxane) with deoxyguanosine and DNA. Chem. Res. Toxicol. 14, 1025\u22121032","author":"Wang M.","year":"2001"},{"key":"tx060232xb00017\/tx060232xb00017_1","volume-title":"Replication of N2-ethyldeoxyguanosine DNA adducts in the human embryonic kidney cell line 293. Chem. Res. Toxicol. 19, 960\u2212967","author":"Upton D. C.","year":"2006"},{"key":"tx060232xn00001\/tx060232xn00001_1","volume-title":"alcohol dehydrogenase gene","author":"Abbreviations ADH"}],"container-title":["Chemical Research in Toxicology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/tx060232x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,10,11]],"date-time":"2021-10-11T01:25:49Z","timestamp":1633915549000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/tx060232x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,12,9]]},"references-count":18,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2007,1,1]]}},"alternative-id":["10.1021\/tx060232x"],"URL":"https:\/\/doi.org\/10.1021\/tx060232x","relation":{},"ISSN":["0893-228X","1520-5010"],"issn-type":[{"value":"0893-228X","type":"print"},{"value":"1520-5010","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,12,9]]}}}