{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T19:18:20Z","timestamp":1792005500829,"version":"4.4.0"},"reference-count":64,"publisher":"American Chemical Society (ACS)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Chem. Res. Toxicol."],"published-print":{"date-parts":[[2012,4,16]]},"DOI":"10.1021\/tx200529v","type":"journal-article","created":{"date-parts":[[2012,3,10]],"date-time":"2012-03-10T00:20:10Z","timestamp":1331338810000},"page":"904-919","source":"Crossref","is-referenced-by-count":159,"title":["Prooxidant and Proinflammatory Potency of Air Pollution Particulate Matter (PM<sub>2.5\u20130.3<\/sub>) Produced in Rural, Urban, or Industrial Surroundings in Human Bronchial Epithelial Cells (BEAS-2B)"],"prefix":"10.1021","volume":"25","author":[{"given":"Mona","family":"Dergham","sequence":"first","affiliation":[{"name":"Universit\u00e9 Lille Nord de France, Lille, France"},{"name":"Universit\u00e9 du Littoral-C\u00f4te d\u2019Opale, EA 4492, Dunkerque, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Capucine","family":"Lepers","sequence":"additional","affiliation":[{"name":"Universit\u00e9 Lille Nord de France, Lille, France"},{"name":"Universit\u00e9 du Littoral-C\u00f4te d\u2019Opale, EA 4492, Dunkerque, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anthony","family":"Verdin","sequence":"additional","affiliation":[{"name":"Universit\u00e9 Lille Nord de France, Lille, France"},{"name":"Universit\u00e9 du Littoral-C\u00f4te d\u2019Opale, EA 4492, Dunkerque, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sylvain","family":"Billet","sequence":"additional","affiliation":[{"name":"Universit\u00e9 Lille Nord de France, Lille, France"},{"name":"Universit\u00e9 du Littoral-C\u00f4te d\u2019Opale, EA 4492, Dunkerque, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabrice","family":"Cazier","sequence":"additional","affiliation":[{"name":"Universit\u00e9 Lille Nord de France, Lille, France"},{"name":"Centre Commun de Mesures, Universit\u00e9 du Littoral-C\u00f4te d\u2019Opale, Dunkerque, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dominique","family":"Courcot","sequence":"additional","affiliation":[{"name":"Universit\u00e9 Lille Nord de France, Lille, France"},{"name":"Universit\u00e9 du Littoral-C\u00f4te d\u2019Opale, EA 4492, Dunkerque, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pirouz","family":"Shirali","sequence":"additional","affiliation":[{"name":"Universit\u00e9 Lille Nord de France, Lille, France"},{"name":"Universit\u00e9 du Littoral-C\u00f4te d\u2019Opale, EA 4492, Dunkerque, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guillaume","family":"Gar\u00e7on","sequence":"additional","affiliation":[{"name":"Universit\u00e9 Lille Nord de France, Lille, France"},{"name":"Universit\u00e9 du Littoral-C\u00f4te d\u2019Opale, EA 4492, Dunkerque, France"},{"name":"Universit\u00e9 de Lille 2, EA 4483, Lille, France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2012,3,23]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"crossref","first-page":"941","DOI":"10.1161\/CIRCULATIONAHA.109.857888","volume":"120","author":"Pope C. A.","year":"2009","journal-title":"Circulation"},{"key":"ref2\/cit2","doi-asserted-by":"crossref","first-page":"2331","DOI":"10.1161\/CIR.0b013e3181dbece1","volume":"121","author":"Brook R. D.","year":"2010","journal-title":"Circulation"},{"key":"ref3\/cit3","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1136\/thx.2010.155358","volume":"66","author":"Peacock J. L.","year":"2011","journal-title":"Thorax"},{"key":"ref4\/cit4","doi-asserted-by":"crossref","first-page":"860","DOI":"10.1289\/ehp.1002353","volume":"19","author":"Raaschou-Nielsen O.","year":"2011","journal-title":"Environ. Health Perspect."},{"key":"ref5\/cit5","doi-asserted-by":"crossref","first-page":"84","DOI":"10.3109\/02770903.2010.538106","volume":"48","author":"Rusconi F.","year":"2011","journal-title":"J. Asthma"},{"key":"ref6\/cit6","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1289\/ehp.9537","volume":"115","author":"Maynard D.","year":"2007","journal-title":"Environ. Health Perspect."},{"key":"ref7\/cit7","doi-asserted-by":"crossref","first-page":"618","DOI":"10.1016\/j.chemosphere.2010.11.073","volume":"83","author":"Osornio-Vargas A. R.","year":"2011","journal-title":"Chemosphere"},{"key":"ref8\/cit8","doi-asserted-by":"crossref","first-page":"1368","DOI":"10.1016\/j.chemosphere.2009.12.071","volume":"78","author":"Perrone M. G.","year":"2010","journal-title":"Chemosphere"},{"key":"ref9\/cit9","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1080\/15287390903248901","volume":"73","author":"Sawyer K.","year":"2010","journal-title":"J. Toxicol. Environ. Health, Part A"},{"key":"ref10\/cit10","doi-asserted-by":"crossref","first-page":"780","DOI":"10.1248\/bpb.33.780","volume":"33","author":"Yoshida T.","year":"2010","journal-title":"Biol. Pharm. Bull."},{"key":"ref11\/cit11","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1080\/08958370701492987","volume":"19","author":"Alfaro-Moreno E.","year":"2007","journal-title":"Inhal. Toxicol."},{"key":"ref12\/cit12","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1016\/j.tox.2009.05.007","volume":"26","author":"Baulig A.","year":"2009","journal-title":"Toxicology"},{"key":"ref13\/cit13","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1021\/tx100407m","volume":"24","author":"Danielsen P. H.","year":"2011","journal-title":"Chem. Res. Toxicol."},{"key":"ref14\/cit14","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1016\/j.tiv.2005.09.012","volume":"20","author":"Gar\u00e7on G.","year":"2006","journal-title":"Toxicol. in Vitro"},{"key":"ref15\/cit15","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.tiv.2009.09.013","volume":"24","author":"Gualtieri M.","year":"2010","journal-title":"Toxicol. in Vitro"},{"key":"ref16\/cit16","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1016\/j.canlet.2008.04.044","volume":"270","author":"Billet S.","year":"2008","journal-title":"Cancer Lett."},{"key":"ref17\/cit17","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1016\/j.envres.2007.03.001","volume":"105","author":"Billet S.","year":"2007","journal-title":"Environ. Res."},{"key":"ref18\/cit18","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/j.tiv.2008.09.020","volume":"2","author":"Abbas I.","year":"2009","journal-title":"Toxicol. in Vitro"},{"key":"ref19\/cit19","doi-asserted-by":"crossref","first-page":"558","DOI":"10.1016\/j.cbi.2010.09.014","volume":"188","author":"Abbas I.","year":"2010","journal-title":"Chem.-Biol. Interact."},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1002\/jat.1722"},{"key":"ref21\/cit21","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1002\/jat.1572","volume":"31","author":"Andr\u00e9 V.","year":"2010","journal-title":"J. Appl. Toxicol."},{"key":"ref22\/cit22","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1002\/jat.1050","volume":"25","author":"Dagher Z.","year":"2005","journal-title":"J. Appl. Toxicol."},{"key":"ref23\/cit23","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/j.tox.2006.04.038","volume":"225","author":"Dagher Z.","year":"2006","journal-title":"Toxicology"},{"key":"ref24\/cit24","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1002\/jat.1211","volume":"27","author":"Dagher Z.","year":"2007","journal-title":"J. Appl. Toxicol."},{"key":"ref25\/cit25","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1016\/j.tox.2007.11.016","volume":"244","author":"Saint-Georges F.","year":"2008","journal-title":"Toxicology"},{"key":"ref26\/cit26","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1016\/j.toxlet.2009.02.016","volume":"187","author":"Saint-Georges F.","year":"2009","journal-title":"Toxicol. Lett."},{"key":"ref27\/cit27","doi-asserted-by":"crossref","first-page":"1999","DOI":"10.1002\/ijc.25815","volume":"128","author":"Lonkar P.","year":"2011","journal-title":"Int. J. Cancer."},{"key":"ref28\/cit28","first-page":"120","volume":"21","author":"Maestrelli P.","year":"2011","journal-title":"J. Invest. Allergol. Clin. Immunol."},{"key":"ref29\/cit29","first-page":"809","volume":"14","author":"Terzano C.","year":"2010","journal-title":"Eur. Rev. Med. Pharmacol. Sci."},{"key":"ref30\/cit30","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/j.tox.2011.03.001","volume":"283","author":"Jomova K.","year":"2011","journal-title":"Toxicology"},{"key":"ref31\/cit31","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/j.mrfmmm.2011.02.015","volume":"711","author":"Ziech D.","year":"2011","journal-title":"Mutat. Res."},{"key":"ref32\/cit32","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1016\/j.envint.2007.09.010","volume":"34","author":"Gualtieri M.","year":"2008","journal-title":"Environ. Int."},{"key":"ref33\/cit33","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1016\/j.mrgentox.2011.04.003","volume":"723","author":"Oh M.","year":"2011","journal-title":"Mutat. Res."},{"key":"ref34\/cit34","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1016\/j.proenv.2011.03.026","volume":"4","author":"Cazier F.","year":"2011","journal-title":"Proc. Environ. Sci."},{"key":"ref35\/cit35","doi-asserted-by":"crossref","unstructured":"Di\u00e9m\u00e9, D., Gar\u00e7on, G., Cabral-N\u2019Dior, M., Billet, S., Verdin, A., Cazier, F., Courcot, D., Diouf, A., and Shirali, P.Relationship between physicochemical characterization and toxicity of fine Particulate Matter (PM2.5) collected in Dakar City (Senegal).Environ. Res. 2011, in press.","DOI":"10.1016\/j.envres.2011.11.009"},{"key":"ref36\/cit36","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/S0300-483X(99)00134-1","volume":"139","author":"Powley M. W.","year":"1999","journal-title":"Toxicology"},{"key":"ref37\/cit37","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/S0300-483X(01)00461-9","volume":"166","author":"Gar\u00e7on G.","year":"2001","journal-title":"Toxicology"},{"key":"ref38\/cit38","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/j.toxlet.2004.01.005","volume":"150","author":"Gar\u00e7on G.","year":"2004","journal-title":"Toxicol. Lett."},{"key":"ref39\/cit39","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1002\/jat.979","volume":"24","author":"Gar\u00e7on G.","year":"2004","journal-title":"J. Appl. Toxicol."},{"key":"ref40\/cit40","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/j.taap.2010.04.014","volume":"246","author":"Naha P. C.","year":"2011","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"ref41\/cit41","first-page":"365","volume":"76","author":"Toyokuni S.","year":"1997","journal-title":"Lab. Invest."},{"key":"ref42\/cit42","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/S0378-4274(00)00231-9","volume":"117","author":"Gar\u00e7on G.","year":"2000","journal-title":"Toxicol. Lett."},{"key":"ref43\/cit43","doi-asserted-by":"crossref","first-page":"1382","DOI":"10.1016\/j.jpba.2006.11.028","volume":"43","author":"Kand\u0301ar R.","year":"2007","journal-title":"J. Pharmaceut. Biomed. Anal."},{"key":"ref44\/cit44","doi-asserted-by":"crossref","first-page":"3274","DOI":"10.1016\/j.jchromb.2009.05.046","volume":"877","author":"McMenamin M. E.","year":"2009","journal-title":"J. Chromatogr., B"},{"key":"ref45\/cit45","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1080\/08958370701490445","volume":"19","author":"Schwarze P. E.","year":"2007","journal-title":"Inhal. Toxicol."},{"key":"ref46\/cit46","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1038\/nnano.2011.58","volume":"6","author":"Cho E. C.","year":"2011","journal-title":"Nat. Nanotechnol."},{"key":"ref47\/cit47","unstructured":"European Parliament and the Council of the European Union (2008) Air Quality-Existing Legislation. Directive 2008\/50\/EC of the European Parliament and of the Council of 21 May 2008 on Ambient Air Quality and Cleaner Air for Europe,http:\/\/eur-lex.europa.eu\/LexUriServ\/LexUriServ.do?uri=CELEX:32008L0050:EN:NOT(retrieved 01.12.2011)."},{"key":"ref48\/cit48","unstructured":"US Code of Federal Regulations (2008) Title 40: Protection of Environment Chapter I, Environmental Protection Agency, continued Part 50, national primary and secondary ambient air quality standards,http:\/\/www.access.gpo.gov\/nara\/cfr\/waisidx_08\/40cfr50_08.html(retrieved 01.12.2011)."},{"key":"ref49\/cit49","unstructured":"World Health Organization (2006) World Health Organization Country Health System Fact Sheet 2006,http:\/\/www.afro.who.int\/home\/countries\/fact_sheets\/ guinea.pdf(retrieved 01.12.2011)."},{"key":"ref50\/cit50","unstructured":"World Health Organization (2006) World Health Organization, Public Health and Environment, PHE, Air Quality Guidelines: Global Update 2005, WHO Air Quality Guidelines for Particulate Matter, Ozone, Nitrogen Dioxide and Sulfur Dioxide, WHO\/SDE\/PHE\/OEH\/06.02,http:\/\/www.who.int\/phe\/health_topics\/outdoorair_aqg\/en\/(retrieved 01.12.2011)."},{"key":"ref51\/cit51","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1016\/j.atmosenv.2006.01.063","volume":"40","author":"Sillanp\u00e4\u00e4 M.","year":"2006","journal-title":"Atmos. Environ."},{"key":"ref52\/cit52","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1006\/taap.2000.9087","volume":"170","author":"Vakharia D. D.","year":"2001","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"ref53\/cit53","first-page":"999","volume":"29","author":"Vakharia D. D.","year":"2001","journal-title":"Drug Metab. Dispos."},{"key":"ref54\/cit54","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1186\/1743-8977-7-41","volume":"7","author":"Totlandsdal A. I.","year":"2010","journal-title":"Part. Fibre Toxicol."},{"key":"ref55\/cit55","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1743-8977-6-24","volume":"6","author":"Araujo J. A.","year":"2009","journal-title":"Part. Fibre Toxicol."},{"key":"ref56\/cit56","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1016\/j.mrfmmm.2010.12.005","volume":"707","author":"Rossner P.","year":"2011","journal-title":"Mutat. Res."},{"issue":"4","key":"ref57\/cit57","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1517\/17425240903579971","volume":"7","author":"Caldorera-Moore M.","year":"2010","journal-title":"Expert Opin. Drug Delivery"},{"key":"ref58\/cit58","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1016\/j.taap.2009.10.017","volume":"242","author":"\u00d8vrevik J.","year":"2010","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"ref59\/cit59","doi-asserted-by":"crossref","first-page":"5985","DOI":"10.1021\/es049476z","volume":"38","author":"Baulig A.","year":"2004","journal-title":"Environ. Sci. Technol."},{"key":"ref60\/cit60","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1080\/08958370701492987","volume":"19","author":"Alfaro-Moreno E.","year":"2007","journal-title":"Inhal. Toxicol."},{"key":"ref61\/cit61","doi-asserted-by":"crossref","first-page":"618","DOI":"10.1016\/j.chemosphere.2010.11.073","volume":"83","author":"Osornio-Vargas A. R.","year":"2011","journal-title":"Chemosphere"},{"key":"ref62\/cit62","doi-asserted-by":"crossref","first-page":"3446","DOI":"10.1016\/j.envpol.2011.08.022","volume":"159","author":"Quintana R.","year":"2011","journal-title":"Environ. Pollut."},{"key":"ref63\/cit63","doi-asserted-by":"crossref","first-page":"1218","DOI":"10.1016\/j.chemosphere.2006.10.078","volume":"67","author":"Rosas Perez I.","year":"2007","journal-title":"Chemosphere"},{"key":"ref64\/cit64","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1289\/ehp.8360","volume":"114","author":"Veranth J. M.","year":"2006","journal-title":"Environ. Health Perspect."}],"container-title":["Chemical Research in Toxicology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/tx200529v","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,4,21]],"date-time":"2024-04-21T08:09:59Z","timestamp":1713686999000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/tx200529v"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,3,23]]},"references-count":64,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2012,4,16]]}},"alternative-id":["10.1021\/tx200529v"],"URL":"https:\/\/doi.org\/10.1021\/tx200529v","relation":{},"ISSN":["0893-228X","1520-5010"],"issn-type":[{"value":"0893-228X","type":"print"},{"value":"1520-5010","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,3,23]]}}}