{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,5]],"date-time":"2026-04-05T07:55:29Z","timestamp":1775375729458,"version":"3.50.1"},"reference-count":49,"publisher":"American Chemical Society (ACS)","issue":"23","funder":[{"DOI":"10.13039\/501100008530","name":"European Regional Development Fund","doi-asserted-by":"publisher","award":["031342"],"award-info":[{"award-number":["031342"]}],"id":[{"id":"10.13039\/501100008530","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100008530","name":"European Regional Development Fund","doi-asserted-by":"publisher","award":["Norte-01-0145-FEDER-000036"],"award-info":[{"award-number":["Norte-01-0145-FEDER-000036"]}],"id":[{"id":"10.13039\/501100008530","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001871","name":"Funda??o para a Ci?ncia e a Tecnologia","doi-asserted-by":"publisher","award":["SFRH\/BD\/90664\/2012"],"award-info":[{"award-number":["SFRH\/BD\/90664\/2012"]}],"id":[{"id":"10.13039\/501100001871","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001871","name":"Funda??o para a Ci?ncia e a Tecnologia","doi-asserted-by":"publisher","award":["031342"],"award-info":[{"award-number":["031342"]}],"id":[{"id":"10.13039\/501100001871","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001871","name":"Funda??o para a Ci?ncia e a Tecnologia","doi-asserted-by":"publisher","award":["SFRH\/BD\/100262\/2014"],"award-info":[{"award-number":["SFRH\/BD\/100262\/2014"]}],"id":[{"id":"10.13039\/501100001871","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001871","name":"Funda??o para a Ci?ncia e a Tecnologia","doi-asserted-by":"publisher","award":["SFRH\/BPD\/72519\/2010"],"award-info":[{"award-number":["SFRH\/BPD\/72519\/2010"]}],"id":[{"id":"10.13039\/501100001871","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Environ. Sci. Technol."],"published-print":{"date-parts":[[2018,12,4]]},"DOI":"10.1021\/acs.est.8b04399","type":"journal-article","created":{"date-parts":[[2018,11,6]],"date-time":"2018-11-06T18:12:08Z","timestamp":1541527928000},"page":"13951-13959","source":"Crossref","is-referenced-by-count":32,"title":["Evolutionary Exploitation of Vertebrate Peroxisome Proliferator-Activated Receptor \u03b3 by Organotins"],"prefix":"10.1021","volume":"52","author":[{"given":"Ana M. F.","family":"Capit\u00e3o","sequence":"first","affiliation":[{"name":"Interdisciplinary Centre of Marine and Environmental Research, University of Porto, 4450-208 Matosinhos, Portugal"},{"name":"Department of Biology, Faculty of Sciences, University of Porto, 4169-007 Porto, Portugal"}]},{"given":"M\u00f3nica S.","family":"Lopes-Marques","sequence":"additional","affiliation":[{"name":"Interdisciplinary Centre of Marine and Environmental Research, University of Porto, 4450-208 Matosinhos, Portugal"}]},{"given":"Yoichiro","family":"Ishii","sequence":"additional","affiliation":[{"name":"Laboratory of Hygienic Chemistry and Molecular Toxicology, Gifu Pharmaceutical University, 1-25-4 Daigaku-nishi, Gifu, Gifu 501-1196, Japan"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2412-8730","authenticated-orcid":true,"given":"Raquel","family":"Ruivo","sequence":"additional","affiliation":[{"name":"Interdisciplinary Centre of Marine and Environmental Research, University of Porto, 4450-208 Matosinhos, Portugal"}]},{"given":"Elza S. S.","family":"Fonseca","sequence":"additional","affiliation":[{"name":"Interdisciplinary Centre of Marine and Environmental Research, University of Porto, 4450-208 Matosinhos, Portugal"},{"name":"Department of Biology, Faculty of Sciences, University of Porto, 4169-007 Porto, Portugal"}]},{"given":"In\u00eas","family":"P\u00e1scoa","sequence":"additional","affiliation":[{"name":"Interdisciplinary Centre of Marine and Environmental Research, University of Porto, 4450-208 Matosinhos, Portugal"}]},{"given":"Rodolfo P.","family":"Jorge","sequence":"additional","affiliation":[{"name":"Interdisciplinary Centre of Marine and Environmental Research, University of Porto, 4450-208 Matosinhos, Portugal"}]},{"given":"M\u00e9lanie A. G.","family":"Barbosa","sequence":"additional","affiliation":[{"name":"Interdisciplinary Centre of Marine and Environmental Research, University of Porto, 4450-208 Matosinhos, Portugal"},{"name":"Department of Biology, Faculty of Sciences, University of Porto, 4169-007 Porto, Portugal"}]},{"given":"Youhei","family":"Hiromori","sequence":"additional","affiliation":[{"name":"Laboratory of Hygienic Chemistry and Molecular Toxicology, Gifu Pharmaceutical University, 1-25-4 Daigaku-nishi, Gifu, Gifu 501-1196, Japan"},{"name":"Faculty of Pharmaceutical Sciences, Suzuka University of Medical Science 3500-3 Minamitamagaki, Suzuka, Mie 513-8670, Japan"}]},{"given":"Takayuki","family":"Miyagi","sequence":"additional","affiliation":[{"name":"Laboratory of Hygienic Chemistry and Molecular Toxicology, Gifu Pharmaceutical University, 1-25-4 Daigaku-nishi, Gifu, Gifu 501-1196, Japan"}]},{"given":"Tsuyoshi","family":"Nakanishi","sequence":"additional","affiliation":[{"name":"Laboratory of Hygienic Chemistry and Molecular Toxicology, Gifu Pharmaceutical University, 1-25-4 Daigaku-nishi, Gifu, Gifu 501-1196, Japan"}]},{"given":"Miguel M.","family":"Santos","sequence":"additional","affiliation":[{"name":"Interdisciplinary Centre of Marine and Environmental Research, University of Porto, 4450-208 Matosinhos, Portugal"},{"name":"Department of Biology, Faculty of Sciences, University of Porto, 4169-007 Porto, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7697-386X","authenticated-orcid":true,"given":"L. Filipe C.","family":"Castro","sequence":"additional","affiliation":[{"name":"Interdisciplinary Centre of Marine and Environmental Research, University of Porto, 4450-208 Matosinhos, Portugal"},{"name":"Department of Biology, Faculty of Sciences, University of Porto, 4169-007 Porto, Portugal"}]}],"member":"316","published-online":{"date-parts":[[2018,11,6]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-018-28498-4"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1089\/107555302317371479"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1210\/en.2005-1129"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1124\/mol.104.008409"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1289\/ehp.120-a62"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1038\/nm1025"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1210\/me.2005-0367"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1016\/j.envint.2017.06.003"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0143911"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1016\/j.taap.2016.01.014"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1016\/j.cbpc.2007.04.009"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1289\/ehp.1409163"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1021\/acs.est.6b04768"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1093\/toxsci\/kfu036"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1897\/08-347.1"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1016\/j.chemosphere.2012.10.078"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1021\/es501697b"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.2174\/978160805265311201010083"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1093\/toxsci\/kfr140"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1038\/embor.2009.8"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1038\/srep08520"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1016\/j.cbpc.2010.10.008"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1016\/j.jsbmb.2011.01.005"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1016\/j.mce.2013.02.011"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gki198"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1093\/bib\/bbn013"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1093\/sysbio\/syq010"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1101\/gr.6316407"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1038\/nature06967"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkw1129"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/bti770"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gku340"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btq662"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkp322"},{"key":"ref35\/cit35","unstructured":"Schrodinger, L. The PyMOL Molecular Graphics System, Version 1.3, 2010."},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1016\/j.chemosphere.2017.05.064"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pgen.0030188"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1016\/j.cbpb.2017.04.005"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1210\/en.2004-1638"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0121259"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0176024"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1093\/gbe\/evw305"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1038\/nature03025"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1038\/ng.3526"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1016\/j.abb.2008.02.003"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1016\/S1097-2765(00)80448-7"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.1038\/srep08520"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.1016\/j.etap.2015.06.009"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.1194\/jlr.D017012"}],"container-title":["Environmental Science & Technology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.est.8b04399","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,26]],"date-time":"2023-04-26T09:41:04Z","timestamp":1682502064000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acs.est.8b04399"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,11,6]]},"references-count":49,"journal-issue":{"issue":"23","published-print":{"date-parts":[[2018,12,4]]}},"alternative-id":["10.1021\/acs.est.8b04399"],"URL":"https:\/\/doi.org\/10.1021\/acs.est.8b04399","relation":{},"ISSN":["0013-936X","1520-5851"],"issn-type":[{"value":"0013-936X","type":"print"},{"value":"1520-5851","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,11,6]]}}}