{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,4]],"date-time":"2025-11-04T16:06:19Z","timestamp":1762272379218,"version":"3.37.3"},"reference-count":54,"publisher":"American Chemical Society (ACS)","issue":"17","license":[{"start":{"date-parts":[[2019,4,9]],"date-time":"2019-04-09T00:00:00Z","timestamp":1554768000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2019,4,9]],"date-time":"2019-04-09T00:00:00Z","timestamp":1554768000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2019,4,9]],"date-time":"2019-04-09T00:00:00Z","timestamp":1554768000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/501100001871","name":"Funda??o para a Ci?ncia e a Tecnologia","doi-asserted-by":"publisher","award":["PD\/BD\/114315\/2016","UID\/EQU\/50020\/2019"],"award-info":[{"award-number":["PD\/BD\/114315\/2016","UID\/EQU\/50020\/2019"]}],"id":[{"id":"10.13039\/501100001871","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001655","name":"Deutscher Akademischer Austauschdienst","doi-asserted-by":"publisher","award":["57340264"],"award-info":[{"award-number":["57340264"]}],"id":[{"id":"10.13039\/501100001655","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002347","name":"Bundesministerium f?r Bildung und Forschung","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002347","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["EXC 1069"],"award-info":[{"award-number":["EXC 1069"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]},{"name":"AIProcMat@N2020","award":["NORTE-01-0145-FEDER-000006"],"award-info":[{"award-number":["NORTE-01-0145-FEDER-000006"]}]},{"name":"Ac??o Integrada","award":["A08\/17"],"award-info":[{"award-number":["A08\/17"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ind. Eng. Chem. Res."],"published-print":{"date-parts":[[2019,5,1]]},"DOI":"10.1021\/acs.iecr.9b00742","type":"journal-article","created":{"date-parts":[[2019,4,9]],"date-time":"2019-04-09T18:31:24Z","timestamp":1554834684000},"page":"7362-7369","source":"Crossref","is-referenced-by-count":39,"title":["Toward Thermodynamic Predictions of Aqueous Vitamin Solubility: An Activity Coefficient-Based Approach"],"prefix":"10.1021","volume":"58","author":[{"given":"Kamila","family":"Wysoczanska","sequence":"first","affiliation":[{"name":"Associate Laboratory of Separation and Reaction Engineering\u2212Laboratory of Catalysis and Materials (LSRE-LCM), Faculty of Engineering, University of Porto, Rua Dr. Roberto Frias, 4200-465 Porto, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5038-9152","authenticated-orcid":true,"given":"Gabriele","family":"Sadowski","sequence":"additional","affiliation":[{"name":"Department of Biochemical and Chemical Engineering, Laboratory of Thermodynamics, Technische Universit\u00e4t Dortmund, Emil-Figge-Strasse 70, 44227 Dortmund, Germany"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3324-4733","authenticated-orcid":true,"given":"Eug\u00e9nia A.","family":"Macedo","sequence":"additional","affiliation":[{"name":"Associate Laboratory of Separation and Reaction Engineering\u2212Laboratory of Catalysis and Materials (LSRE-LCM), Faculty of Engineering, University of Porto, Rua Dr. Roberto Frias, 4200-465 Porto, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1074-177X","authenticated-orcid":true,"given":"Christoph","family":"Held","sequence":"additional","affiliation":[{"name":"Department of Biochemical and Chemical Engineering, Laboratory of Thermodynamics, Technische Universit\u00e4t Dortmund, Emil-Figge-Strasse 70, 44227 Dortmund, Germany"}]}],"member":"316","published-online":{"date-parts":[[2019,4,9]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.2174\/138920211796429736"},{"volume-title":"The Vitamins: Fundamental Aspects in Nutrition and Health","year":"2007","author":"Combs G. F.","key":"ref2\/cit2"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1038\/ki.1993.185"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1006\/mgme.2000.3027"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1016\/j.bios.2013.11.074"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1016\/j.fluid.2010.08.025"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1021\/ja0474143"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.200500611"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.2147\/OTT.S113815"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.5402\/2012\/195727"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1002\/aic.690210607"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1002\/aic.690280410"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1021\/ie9600203"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1039\/P29930000799"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1016\/0378-3812(89)80308-5"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1016\/j.fluid.2011.01.014"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajps.2017.12.004"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1016\/j.fluid.2009.11.018"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1016\/S0378-3812(00)00302-2"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1021\/acs.iecr.5b00068"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1021\/acs.cgd.6b00024"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1002\/aic.14212"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1021\/ie100088c"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1021\/ie302064h"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1016\/j.tca.2012.10.017"},{"key":"ref26\/cit26","first-page":"311","volume":"10","author":"Seng C.","year":"1987","journal-title":"Pertanika"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1021\/je800056h"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1016\/j.jct.2011.11.023"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2007.05.008"},{"key":"ref30\/cit30","first-page":"1703","volume":"126","author":"Berthelot D.","year":"1898","journal-title":"Compt. Rendus"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1002\/andp.18812480110"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1021\/ie970781l"},{"key":"ref33\/cit33","volume-title":"Molecular Thermodynamics of Fluid-Phase Equilibria","author":"Prausnitz J. M.","year":"1998","edition":"3"},{"key":"ref34\/cit34","doi-asserted-by":"crossref","DOI":"10.1201\/EBK1439802458","volume-title":"Handbook of Aqueous Solubility Data","author":"Yalkowsky S. H.","year":"2016"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1021\/je1000268"},{"key":"ref36\/cit36","volume-title":"Profiles of Drug Substances, Excipients and Related Methodology: Critical Compilation of pKa Values for Pharmaceutical Substances","volume":"33","author":"Brittain H. G.","year":"2007"},{"key":"ref37\/cit37","volume-title":"Pyridine and its Derivatives","volume":"32","author":"Klingsberg E.","year":"2009"},{"volume-title":"Riboflavin","year":"2012","author":"Rivlin R.","key":"ref38\/cit38"},{"key":"ref39\/cit39","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1016\/S0021-9258(18)74634-6","volume":"116","author":"Michaelis L.","year":"1936","journal-title":"J. Biol. Chem."},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1002\/cber.19340670720"},{"key":"ref41\/cit41","unstructured":"Suelter, C. H., Mechanism of Oxidation of Reduced Pyridine Nucleotide Analogs by Riboflavin. Ph.D Thesis. Iowa State University, 1959."},{"key":"ref42\/cit42","unstructured":"Chemicalize Calculation\nModule; ChemAxon, 2019."},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1002\/elps.200600128"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1016\/j.xphs.2017.08.007"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1021\/ie0602097"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1016\/j.fluid.2015.07.004"},{"key":"ref47\/cit47","unstructured":"Chemicalize Calculation Module; ChemAxon, 2018."},{"key":"ref48\/cit48","unstructured":"Compound\nSummary; PubChem, 2018; https:\/\/pubchem.ncbi.nlm.nih.gov."},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.1016\/S0040-6031(99)00301-9"},{"volume-title":"CRC Handbook of Chemistry and Physics","year":"2007","author":"Lide D. R.","key":"ref50\/cit50"},{"key":"ref51\/cit51","doi-asserted-by":"publisher","DOI":"10.1016\/j.jct.2012.06.010"},{"key":"ref52\/cit52","unstructured":"Bradley, J.C.; Williams, A.; Lang, A. Jean-Claude Bradley Open Melting Point Dataset; figshare, 2014."},{"key":"ref53\/cit53","unstructured":"Cyanocobalamin: Specifications; bioWORLD, 2018; https:\/\/www.bio-world.com."},{"key":"ref54\/cit54","doi-asserted-by":"publisher","DOI":"10.1002\/jsfa.2740221011"}],"container-title":["Industrial & Engineering Chemistry Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.iecr.9b00742","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,15]],"date-time":"2023-04-15T23:59:22Z","timestamp":1681603162000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acs.iecr.9b00742"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,4,9]]},"references-count":54,"journal-issue":{"issue":"17","published-print":{"date-parts":[[2019,5,1]]}},"alternative-id":["10.1021\/acs.iecr.9b00742"],"URL":"https:\/\/doi.org\/10.1021\/acs.iecr.9b00742","relation":{},"ISSN":["0888-5885","1520-5045"],"issn-type":[{"type":"print","value":"0888-5885"},{"type":"electronic","value":"1520-5045"}],"subject":[],"published":{"date-parts":[[2019,4,9]]}}}