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M.","year":"2015","journal-title":"ChemPhysChem"},{"key":"ref35\/cit35","doi-asserted-by":"crossref","first-page":"5220","DOI":"10.1002\/anie.201209731","volume":"52","author":"Philippaerts A.","year":"2013","journal-title":"Angew. Chem., Int. Ed."},{"key":"ref36\/cit36a","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1016\/0140-6736(93)90350-P","volume":"341","author":"Willett W. C.","year":"1993","journal-title":"Lancet"},{"key":"ref36\/cit36b","doi-asserted-by":"crossref","first-page":"1601","DOI":"10.1056\/NEJMra054035","volume":"354","author":"Mozaffarian D.","year":"2006","journal-title":"New Engl. J. Med."},{"key":"ref37\/cit37","doi-asserted-by":"crossref","first-page":"1017S","DOI":"10.1093\/ajcn\/60.6.1017S","volume":"60","author":"Katan M. B.","year":"1994","journal-title":"Am. J. Clin. Nutr."},{"key":"ref38\/cit38","volume-title":"Guidance for Industry: Trans Fatty Acids in Nutrition Labeling, Nutrient Content Claims, Health Claims; Small Entity Compliance Guide","author":"US Food and Drug Administration","year":"2003"},{"key":"ref39\/cit39","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1038\/scientificamerican0314-13","volume":"310","author":"Willett W.","year":"2014","journal-title":"Sci. Am."},{"key":"ref40\/cit40","volume-title":"Trans Fats: The Health Burden","year":"2007"},{"key":"ref41\/cit41","doi-asserted-by":"crossref","first-page":"7219","DOI":"10.1021\/ie800663j","volume":"47","author":"Simakova L. I.","year":"2008","journal-title":"Ind. Eng. Chem. Res."},{"key":"ref42\/cit42","volume-title":"Handbook of Heterogeneous Catalytic Hydrogenation for Organic Synthesis","author":"Nishimura S.","year":"2001"},{"key":"ref43\/cit43","doi-asserted-by":"crossref","first-page":"1241","DOI":"10.1016\/S0008-6223(00)00026-9","volume":"38","author":"Gurrath M.","year":"2000","journal-title":"Carbon"},{"key":"ref44\/cit44","unstructured":"Bonrath, W.; Buss, A.WO 2013124391, 2013."},{"key":"ref45\/cit45","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1002\/cssc.200800168","volume":"2","author":"Schm\u00f6ger C.","year":"2009","journal-title":"ChemSusChem"},{"key":"ref46\/cit46a","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1039\/B815566F","volume":"11","author":"Morrissey S.","year":"2009","journal-title":"Green Chem."},{"key":"ref46\/cit46b","doi-asserted-by":"crossref","first-page":"853","DOI":"10.1038\/nmat2849","volume":"9","author":"Marshall S. T.","year":"2010","journal-title":"Nat. Mater."},{"key":"ref47\/cit47","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1002\/adsc.201100569","volume":"354","author":"Kantam M. L.","year":"2012","journal-title":"Adv. Synth. Catal."},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.1002\/cctc.201402668"},{"key":"ref49\/cit49","volume-title":"Ullmann\u2019s Encyclopedia of Industrial Chemistry","author":"Booth G.","year":"2000"},{"key":"ref50\/cit50","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1002\/cctc.200900129","volume":"1","author":"Blaser H.-U.","year":"2009","journal-title":"ChemCatChem"},{"key":"ref51\/cit51","doi-asserted-by":"crossref","first-page":"1601","DOI":"10.1021\/ol800277a","volume":"10","author":"Takasaki M.","year":"2008","journal-title":"Org. Lett."},{"key":"ref52\/cit52","doi-asserted-by":"crossref","first-page":"4250","DOI":"10.1016\/j.tetlet.2010.06.024","volume":"51","author":"Chang F.","year":"2010","journal-title":"Tetrahedron Lett."},{"key":"ref53\/cit53","doi-asserted-by":"crossref","first-page":"822","DOI":"10.1002\/adsc.200800018","volume":"350","author":"Lakshmi Kantam M.","year":"2008","journal-title":"Adv. Synth. Catal."},{"key":"ref54\/cit54","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/S1381-1169(01)00151-0","volume":"173","author":"Figueras F.","year":"2001","journal-title":"J. Mol. Catal. A: Chem."},{"key":"ref55\/cit55","doi-asserted-by":"crossref","first-page":"1306","DOI":"10.1002\/adsc.201000945","volume":"353","author":"Pandarus V.","year":"2011","journal-title":"Adv. Synth. Catal."},{"key":"ref56\/cit56","doi-asserted-by":"crossref","first-page":"1333","DOI":"10.1002\/cctc.201301037","volume":"6","author":"Li Z.","year":"2014","journal-title":"ChemCatChem."},{"key":"ref57\/cit57","doi-asserted-by":"crossref","first-page":"6227","DOI":"10.1002\/ejoc.201300290","volume":"2013","author":"Pagliaro M.","year":"2013","journal-title":"Eur. J. Org. Chem."},{"key":"ref58\/cit58","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1021\/op900059x","volume":"14","author":"Ciriminna R.","year":"2009","journal-title":"Org. Process Res. Dev."},{"key":"ref59\/cit59","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1002\/adsc.200303016","volume":"345","author":"Reetz M. T.","year":"2003","journal-title":"Adv. Synth. Catal."},{"key":"ref60\/cit60","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1002\/1615-4169(200202)344:2<159::AID-ADSC159>3.0.CO;2-Q","volume":"344","author":"Ciriminna R.","year":"2002","journal-title":"Adv. Synth. Catal."},{"key":"ref61\/cit61","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1039\/b505949f","volume":"3","author":"Gancitano P.","year":"2005","journal-title":"Org. Biomol. Chem."},{"key":"ref62\/cit62","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1002\/adsc.200303239","volume":"346","author":"Testa M. L.","year":"2004","journal-title":"Adv. Synth. Catal."},{"key":"ref63\/cit63","doi-asserted-by":"crossref","first-page":"195","DOI":"10.15227\/orgsyn.081.0195","volume":"81","author":"Zhao M. M.","year":"2005","journal-title":"Org. Synth."},{"key":"ref64\/cit64","doi-asserted-by":"crossref","first-page":"756","DOI":"10.1039\/b820197h","volume":"11","author":"Ni J.","year":"2009","journal-title":"Green Chem."},{"key":"ref65\/cit65","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1002\/cctc.201402861","volume":"7","author":"Ciriminna R.","year":"2015","journal-title":"ChemCatChem."},{"key":"ref66\/cit66","doi-asserted-by":"crossref","first-page":"756","DOI":"10.1039\/b820197h","volume":"11","author":"Ni J.","year":"2009","journal-title":"Green Chem."},{"key":"ref67\/cit67","unstructured":"Ciriminna, R.To be submitted for publication, 2015."},{"key":"ref68\/cit68","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1039\/B703488C","volume":"9","author":"Constable D. J. C.","year":"2007","journal-title":"Green Chem."},{"key":"ref69\/cit69","doi-asserted-by":"crossref","first-page":"3196","DOI":"10.1002\/anie.201410884","volume":"54","author":"Whitesides G. M.","year":"2015","journal-title":"Angew. 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